The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1LIFE HEALTHCARE INC COM 68269G107 56,689 3,123,384 SH   SOLE   3,123,384 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 11,512 414,400 SH   SOLE   414,400 0 0
AKERO THERAPEUTICS INC COM 00973Y108 12,074 569,513 SH   SOLE   569,513 0 0
ALLAKOS INC COM 01671P100 132,444 2,976,928 SH   SOLE   2,976,928 0 0
AMEDISYS INC COM 023436108 32,590 177,565 SH   SOLE   177,565 0 0
AMICUS THERAPEUTICS INC COM 03152W109 232,677 25,181,500 SH   SOLE   25,181,500 0 0
APREA THERAPEUTICS INC COM 03836J102 78,861 2,268,718 SH   SOLE   2,268,718 0 0
ARDELYX INC COM 039697107 22,195 3,904,100 SH   SOLE   3,904,100 0 0
ARGENX SE SPONSORED ADR 04016X101 142,541 1,082,070 SH   SOLE   1,082,070 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 45,047 5,293,370 SH   SOLE   5,293,370 0 0
ATRECA INC CL A COM 04965G109 18,682 1,128,806 SH   SOLE   1,128,806 0 0
AXONICS MODULATION TECHNOLOG COM 05465P101 38,303 1,507,400 SH   SOLE   1,507,400 0 0
BEAM THERAPEUTICS INC COM 07373V105 60,467 3,359,258 SH   SOLE   3,359,258 0 0
BIOGEN INC COM 09062X103 186,443 589,300 SH   SOLE   589,300 0 0
BIONTECH SE SPONSORED ADS 09075V102 9,940 170,200 SH   SOLE   170,200 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 99/99/9999 110122157 9,078 2,389,000 SH   SOLE   2,389,000 0 0
CABALETTA BIO INC COM 12674W109 10,409 1,425,896 SH   SOLE   1,425,896 0 0
CASTLIGHT HEALTH INC CL B 14862Q100 7 10,229 SH   SOLE   10,229 0 0
CATALENT INC COM 148806102 26,302 506,300 SH   SOLE   506,300 0 0
CENTENE CORP DEL COM 15135B101 48,959 824,090 SH   SOLE   824,090 0 0
CIGNA CORP NEW COM 125523100 53,260 300,600 SH   SOLE   300,600 0 0
CLOVIS ONCOLOGY INC COM 189464100 633 99,485 SH   SOLE   99,485 0 0
CRYOPORT INC COM PAR $0.001 229050307 31,028 1,817,663 SH   SOLE   1,817,663 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 4,071 2,750,616 SH   SOLE   2,750,616 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 210,637 5,116,263 SH   SOLE   5,116,263 0 0
DEXCOM INC COM 252131107 34,817 129,300 SH   SOLE   129,300 0 0
EIDOS THERAPEUTICS INC COM 28249H104 33,778 689,478 SH   SOLE   689,478 0 0
ENDOLOGIX INC COM NEW 29266S304 54 78,755 SH   SOLE   78,755 0 0
EPIZYME INC COM 29428V104 135,999 8,768,475 SH   SOLE   8,768,475 0 0
FATE THERAPEUTICS INC COM 31189P102 249,125 11,216,809 SH   SOLE   11,216,809 0 0
GENMAB A/S SPONSORED ADS 372303206 32,823 1,549,000 SH   SOLE   1,549,000 0 0
GLYCOMIMETICS INC COM 38000Q102 578 253,516 SH   SOLE   253,516 0 0
GOSSAMER BIO INC COM 38341P102 2,636 259,700 SH   SOLE   259,700 0 0
GRITSTONE ONCOLOGY INC COM 39868T105 17,857 3,068,194 SH   SOLE   3,068,194 0 0
HOOKIPA PHARMA INC COM 43906K100 15,366 1,862,510 SH   SOLE   1,862,510 0 0
IGM BIOSCIENCES INC COM 449585108 176,536 3,144,000 SH   SOLE   3,144,000 0 0
IMMUNOGEN INC COM 45253H101 57,063 16,733,879 SH   SOLE   16,733,879 0 0
ITAMAR MED LTD SPONSORED ADS 465437101 7,363 625,000 SH   SOLE   625,000 0 0
KRYSTAL BIOTECH INC COM 501147102 45,480 1,051,800 SH   SOLE   1,051,800 0 0
MERCK & CO. INC COM 58933Y105 60,667 788,500 SH   SOLE   788,500 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 140,760 5,175,008 SH   SOLE   5,175,008 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 45,989 4,041,211 SH   SOLE   4,041,211 0 0
NEVRO CORP COM 64157F103 70,628 706,426 SH   SOLE   706,426 0 0
NOVARTIS A G SPONSORED ADR 66987V109 53,889 653,600 SH   SOLE   653,600 0 0
ODONATE THERAPEUTICS INC COM 676079106 19,549 708,038 SH   SOLE   708,038 0 0
OVID THERAPEUTICS INC COM 690469101 363 121,950 SH   SOLE   121,950 0 0
PPD INC COM 69355F102 22,990 1,290,832 SH   SOLE   1,290,832 0 0
PRA HEALTH SCIENCES INC COM 69354M108 36,762 442,700 SH   SOLE   442,700 0 0
PRINCIPIA BIOPHARMA INC COM 74257L108 134,263 2,261,088 SH   SOLE   2,261,088 0 0
PROFOUND MED CORP COM NEW 74319B502 3,896 400,000 SH   SOLE   400,000 0 0
REGENXBIO INC COM 75901B107 75,720 2,338,466 SH   SOLE   2,338,466 0 0
REPLIMUNE GROUP INC COM 76029N106 29,716 2,980,493 SH   SOLE   2,980,493 0 0
REVOLUTION MEDICINES INC COM 76155X100 6,647 303,371 SH   SOLE   303,371 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 34,999 2,890,089 SH   SOLE   2,890,089 0 0
SEATTLE GENETICS INC COM 812578102 75,655 655,700 SH   SOLE   655,700 0 0
SHOCKWAVE MED INC COM 82489T104 18,508 557,800 SH   SOLE   557,800 0 0
STEREOTAXIS INC COM NEW 85916J409 9,372 3,103,327 SH   SOLE   3,103,327 0 0
STOKE THERAPEUTICS INC COM 86150R107 49,600 2,165,938 SH   SOLE   2,165,938 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 1,259 212,291 SH   SOLE   212,291 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 56,709 881,266 SH   SOLE   881,266 0 0
TCR2 THERAPEUTICS INC COM 87808K106 13,679 1,767,288 SH   SOLE   1,767,288 0 0
TRICIDA INC COM 89610F101 46,785 2,126,600 SH   SOLE   2,126,600 0 0
TWIST BIOSCIENCE CORP COM 90184D100 18,048 590,200 SH   SOLE   590,200 0 0
UNIQURE NV SHS N90064101 131,604 2,773,525 SH   SOLE   2,773,525 0 0
UNITEDHEALTH GROUP INC COM 91324P102 60,126 241,100 SH   SOLE   241,100 0 0
VAPOTHERM INC COM 922107107 471 25,000 SH   SOLE   25,000 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 27,429 2,927,352 SH   SOLE   2,927,352 0 0
XERIS PHARMACEUTICALS INC COM 98422L107 5,767 2,957,441 SH   SOLE   2,957,441 0 0
ZYMEWORKS INC COM 98985W102 30,809 868,600 SH   SOLE   868,600 0 0