The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACADIA PHARMACEUTICALS INC | Common | 004225108 | 6,126 | 145,000 | SH | SOLE | 145,000 | 0 | 0 | ||
| ACCELERON PHARMA INC | Common | 00434H108 | 77,288 | 860,000 | SH | SOLE | 860,000 | 0 | 0 | ||
| ADVERUM BIOTECHNOLOGIES INC | Common | 00773U108 | 69,856 | 7,150,000 | SH | SOLE | 7,150,000 | 0 | 0 | ||
| AGENUS INC | Common | 00847G705 | 6,738 | 2,750,000 | SH | SOLE | 2,750,000 | 0 | 0 | ||
| ALIMERA SCIENCES INC | Common | 016259202 | 1,597 | 415,999 | SH | SOLE | 415,999 | 0 | 0 | ||
| ALLOGENE THERAPEUTICS INC | Common | 019770106 | 21,940 | 1,128,594 | SH | SOLE | 1,128,594 | 0 | 0 | ||
| AMARIN CORP PLC | Sponsored ADR | 023111206 | 8,000 | 2,000,000 | SH | SOLE | 2,000,000 | 0 | 0 | ||
| AMARIN CORP PLC | Sponsored ADR | 023111206 | 10 | 1,000,000 | SH | Call | SOLE | 1,000,000 | 0 | 0 | |
| AMICUS THERAPEUTICS INC | Common | 03152W109 | 101,178 | 10,950,000 | SH | SOLE | 10,950,000 | 0 | 0 | ||
| ARGENX SE | Sponsored ADR | 04016X101 | 123,365 | 936,500 | SH | SOLE | 936,500 | 0 | 0 | ||
| ASCENDIS PHARMA | Sponsored ADR | 04351P101 | 201,234 | 1,787,000 | SH | SOLE | 1,787,000 | 0 | 0 | ||
| ATHENEX INC | Common | 04685N103 | 37,733 | 4,875,000 | SH | SOLE | 4,875,000 | 0 | 0 | ||
| AURINIA PHARMACEUTICALS INC | Common | 05156V102 | 25,030 | 1,725,000 | SH | SOLE | 1,725,000 | 0 | 0 | ||
| AVADEL PHARMACEUTICALS PLC | Sponsored ADR | 05337M104 | 34,663 | 4,365,655 | SH | SOLE | 4,365,655 | 0 | 0 | ||
| BIODELIVERY SCIENCES INTL | Common | 09060J106 | 11,370 | 3,000,000 | SH | SOLE | 3,000,000 | 0 | 0 | ||
| BIOMARIN PHARMACEUTICAL INC | Common | 09061G101 | 163,085 | 1,930,000 | SH | SOLE | 1,930,000 | 0 | 0 | ||
| BLACK DIAMOND THERAPEUTICS INC | Common | 09203E105 | 13,018 | 521,750 | SH | SOLE | 521,750 | 0 | 0 | ||
| CONSTELLATION PHARMACEUTICALS INC | Common | 210373106 | 114,720 | 3,650,000 | SH | SOLE | 3,650,000 | 0 | 0 | ||
| CUE BIOPHARMA INC | Common | 22978P106 | 26,535 | 1,870,000 | SH | SOLE | 1,870,000 | 0 | 0 | ||
| CYMABAY THERAPEUTICS INC | Common | 23257D103 | 8,140 | 5,500,000 | SH | SOLE | 5,500,000 | 0 | 0 | ||
| DECIPHERA PHARMACEUTICALS INC | Common | 24344T101 | 82,340 | 2,000,000 | SH | SOLE | 2,000,000 | 0 | 0 | ||
| FENNEC PHARMACEUTICALS INC | Common | 31447P100 | 6,570 | 1,105,999 | SH | SOLE | 1,105,999 | 0 | 0 | ||
| HORIZON THERAPEUTICS PLC | Common | G46188101 | 135,512 | 4,575,000 | SH | SOLE | 4,575,000 | 0 | 0 | ||
| IMMUNOGEN INC | Common | 45253H101 | 6,479 | 1,900,000 | SH | SOLE | 1,900,000 | 0 | 0 | ||
| IMMUNOMEDICS INC | Common | 452907108 | 330,260 | 24,500,000 | SH | SOLE | 24,500,000 | 0 | 0 | ||
| IOVANCE BIOTHERAPEUTICS INC | Common | 462260100 | 269,727 | 9,010,413 | SH | SOLE | 9,010,413 | 0 | 0 | ||
| IOVANCE BIOTHERAPEUTICS INC | Common | 462260100 | 3,125 | 1,250,000 | SH | Call | SOLE | 1,250,000 | 0 | 0 | |
| KARYOPHARM THERAPEUTICS INC | Common | 48576U106 | 134,470 | 7,000,000 | SH | SOLE | 7,000,000 | 0 | 0 | ||
| MADRIGAL PHARMACEUTICALS INC | Common | 558868105 | 23,299 | 349,000 | SH | SOLE | 349,000 | 0 | 0 | ||
| MARINUS PHARMACEUTICALS INC | Common | 56854Q101 | 12,586 | 6,200,000 | SH | SOLE | 6,200,000 | 0 | 0 | ||
| MIRATI THERAPEUTICS INC | Common | 60468T105 | 316,143 | 4,112,700 | SH | SOLE | 4,112,700 | 0 | 0 | ||
| MYOKARDIA INC | Common | 62857M105 | 67,273 | 1,435,000 | SH | SOLE | 1,435,000 | 0 | 0 | ||
| PTC THERAPEUTICS INC | Common | 69366J200 | 53,532 | 1,200,000 | SH | SOLE | 1,200,000 | 0 | 0 | ||
| RELMADA THERAPEUTICS INC | Common | 75955J402 | 39,227 | 1,150,000 | SH | SOLE | 1,150,000 | 0 | 0 | ||
| REVOLUTION MEDICINES INC | Common | 76155X100 | 9,860 | 450,000 | SH | SOLE | 450,000 | 0 | 0 | ||
| SAGE THERAPEUTICS INC | Common | 78667J108 | 28,720 | 1,000,000 | SH | SOLE | 1,000,000 | 0 | 0 | ||
| SAREPTA THERAPEUTICS INC | Common | 803607100 | 155,045 | 1,585,000 | SH | SOLE | 1,585,000 | 0 | 0 | ||
| TG THERAPEUTICS INC | Common | 88322Q108 | 7,872 | 800,000 | SH | SOLE | 800,000 | 0 | 0 | ||
| TRICIDA INC | Common | 89610F101 | 30,030 | 1,365,000 | SH | SOLE | 1,365,000 | 0 | 0 | ||
| TRILLIUM THERAPEUTICS INC | Common | 89620X506 | 19,998 | 4,950,000 | SH | SOLE | 4,950,000 | 0 | 0 | ||
| UNIQURE NV | Common | N90064101 | 78,293 | 1,650,000 | SH | SOLE | 1,650,000 | 0 | 0 | ||
| XENON PHARMACEUTICALS INC | Common | 98420N105 | 31,434 | 2,772,000 | SH | SOLE | 2,772,000 | 0 | 0 | ||
| ZOGENIX INC | Common | 98978L204 | 69,244 | 2,800,000 | SH | SOLE | 2,800,000 | 0 | 0 | ||