The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ADVERUM BIOTECHNOLOGIES INC | COM | 00773U108 | 13,536 | 1,175,000 | SH | SOLE | 1,175,000 | 0 | 0 | ||
| AERIE PHARMACEUTICALS INC | COM | 00771V108 | 13,898 | 575,000 | SH | SOLE | 575,000 | 0 | 0 | ||
| AMARIN CORP PLC | SPONS ADR NEW | 023111206 | 5,360 | 250,000 | SH | Call | SOLE | 250,000 | 0 | 0 | |
| ANAPTYSBIO INC | COM | 032724106 | 187 | 11,500 | SH | SOLE | 11,500 | 0 | 0 | ||
| APELLIS PHARMACEUTICALS INC | COM | 03753U106 | 5,359 | 175,000 | SH | SOLE | 175,000 | 0 | 0 | ||
| APELLIS PHARMACEUTICALS INC | COM | 03753U106 | 7,655 | 250,000 | SH | Call | SOLE | 250,000 | 0 | 0 | |
| APELLIS PHARMACEUTICALS INC | COM | 03753U106 | 9,186 | 300,000 | SH | Put | SOLE | 300,000 | 0 | 0 | |
| ARQULE INC | COM | 04269E107 | 5,988 | 300,000 | SH | SOLE | 300,000 | 0 | 0 | ||
| ARVINAS INC | COM | 04335A105 | 9,245 | 225,000 | SH | SOLE | 225,000 | 0 | 0 | ||
| ASCENDIS PHARMA A S | SPONSORED ADR | 04351P101 | 27,824 | 200,000 | SH | SOLE | 200,000 | 0 | 0 | ||
| AURINIA PHARMACEUTICALS INC | COM | 05156V102 | 12,156 | 600,000 | SH | SOLE | 600,000 | 0 | 0 | ||
| AXSOME THERAPEUTICS INC | COM | 05464T104 | 20,672 | 200,000 | SH | SOLE | 200,000 | 0 | 0 | ||
| BIOCRYST PHARMACEUTICALS | COM | 09058V103 | 10,350 | 3,000,000 | SH | SOLE | 3,000,000 | 0 | 0 | ||
| BIOHAVEN PHARMACTL HLDG CO L | COM | G11196105 | 2,178 | 40,000 | SH | SOLE | 40,000 | 0 | 0 | ||
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 12,017 | 150,000 | SH | SOLE | 150,000 | 0 | 0 | ||
| CHIASMA INC | COM | 16706W102 | 2,108 | 425,000 | SH | SOLE | 425,000 | 0 | 0 | ||
| COHERUS BIOSCIENCES INC | COM | 19249H103 | 7,742 | 430,000 | SH | SOLE | 430,000 | 0 | 0 | ||
| CONSTELLATION PHARMCETICLS I | COM | 210373106 | 27,112 | 575,500 | SH | SOLE | 575,500 | 0 | 0 | ||
| DBV TECHNOLOGIES S A | SPONSORED ADR | 23306J101 | 8,025 | 750,000 | SH | SOLE | 750,000 | 0 | 0 | ||
| FATE THERAPEUTICS INC | COM | 31189P102 | 5,382 | 275,000 | SH | SOLE | 275,000 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | COM | 03152W109 | 12,175 | 1,250,000 | SH | SOLE | 1,250,000 | 0 | 0 | ||
| INVESCO CURNCYSHS BRIT PND S | BRIT POUN STRL | 46138M109 | 1,490 | 11,600 | SH | SOLE | 11,600 | 0 | 0 | ||
| INVESCO CURNCYSHS SWISS FRAN | SWISS FRANC | 46138R108 | 4,949 | 52,000 | SH | SOLE | 52,000 | 0 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 2,655 | 33,400 | SH | SOLE | 33,400 | 0 | 0 | ||
| IMMUNOMEDICS INC | COM | 452907108 | 10,580 | 500,000 | SH | SOLE | 500,000 | 0 | 0 | ||
| IMMUNOVANT INC | COM | 45258J102 | 12,696 | 800,000 | SH | SOLE | 800,000 | 0 | 0 | ||
| INSMED INC | COM PAR $.01 | 457669307 | 4,776 | 200,000 | SH | SOLE | 200,000 | 0 | 0 | ||
| IOVANCE BIOTHERAPEUTICS INC | COM | 462260100 | 17,992 | 650,000 | SH | SOLE | 650,000 | 0 | 0 | ||
| IOVANCE BIOTHERAPEUTICS INC | COM | 462260100 | 9,688 | 350,000 | SH | Call | SOLE | 350,000 | 0 | 0 | |
| IVERIC BIO INC | COM | 46583P102 | 6,435 | 750,000 | SH | SOLE | 750,000 | 0 | 0 | ||
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 | 7,391 | 415,000 | SH | SOLE | 415,000 | 0 | 0 | ||
| KADMON HLDGS INC | COM | 48283N106 | 2,095 | 462,500 | SH | SOLE | 462,500 | 0 | 0 | ||
| KINIKSA PHARMACEUTICALS LTD | COM CL A | G5269C101 | 3,871 | 350,000 | SH | SOLE | 350,000 | 0 | 0 | ||
| KARYOPHARM THERAPEUTICS INC | COM | 48576U106 | 968 | 50,500 | SH | SOLE | 50,500 | 0 | 0 | ||
| MILESTONE PHARMACEUTICALS IN | COM | 59935V107 | 3,762 | 235,000 | SH | SOLE | 235,000 | 0 | 0 | ||
| MOMENTA PHARMACEUTICALS INC | COM | 60877T100 | 7,892 | 400,000 | SH | SOLE | 400,000 | 0 | 0 | ||
| MERSANA THERAPEUTICS INC | COM | 59045L106 | 4,584 | 800,000 | SH | SOLE | 800,000 | 0 | 0 | ||
| MIRATI THERAPEUTICS INC | COM | 60468T105 | 19,329 | 150,000 | SH | SOLE | 150,000 | 0 | 0 | ||
| MYOVANT SCIENCES LTD | COM | G637AM102 | 6,984 | 450,000 | SH | SOLE | 450,000 | 0 | 0 | ||
| ORCHARD THERAPEUTICS PLC | ADS | 68570P101 | 3,085 | 224,359 | SH | SOLE | 224,359 | 0 | 0 | ||
| PHASEBIO PHARMACEUTICALS INC | COM | 717224109 | 2,750 | 450,000 | SH | SOLE | 450,000 | 0 | 0 | ||
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 1,939 | 275,000 | SH | SOLE | 275,000 | 0 | 0 | ||
| ROCKET PHARMACEUTICALS INC | COM | 77313F106 | 15,932 | 700,000 | SH | SOLE | 700,000 | 0 | 0 | ||
| REATA PHARMACEUTICALS INC | CL A | 75615P103 | 15,332 | 75,000 | SH | SOLE | 75,000 | 0 | 0 | ||
| SAGE THERAPEUTICS INC | COM | 78667J108 | 10,829 | 150,000 | SH | Call | SOLE | 150,000 | 0 | 0 | |
| SELECTA BIOSCIENCES INC | COM | 816212104 | 2,737 | 1,150,000 | SH | SOLE | 1,150,000 | 0 | 0 | ||
| SPECTRUM PHARMACEUTICALS INC | COM | 84763A108 | 140 | 38,340 | SH | SOLE | 38,340 | 0 | 0 | ||
| SPDR S&P 500 ETF TR | TR UNIT | 78462F103 | 64,372 | 200,000 | SH | Put | SOLE | 200,000 | 0 | 0 | |
| SAREPTA THERAPEUTICS INC | COM | 803607100 | 8,388 | 65,000 | SH | SOLE | 65,000 | 0 | 0 | ||
| TG THERAPEUTICS INC | COM | 88322Q108 | 699 | 63,000 | SH | SOLE | 63,000 | 0 | 0 | ||
| VIEWRAY INC | COM | 92672L107 | 5,064 | 1,200,000 | SH | SOLE | 1,200,000 | 0 | 0 | ||
| SPDR SERIES TRUST | S&P BIOTECH | 78464A870 | 47,556 | 500,000 | SH | Put | SOLE | 500,000 | 0 | 0 | |