The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 20,048 750,000 SH   SOLE   750,000 0 0
ALLAKOS INC COM 01671P100 455 10,500 SH   SOLE   10,500 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 10,884 150,000 SH   SOLE   150,000 0 0
ARGENX SE SPONSORED ADR 04016X101 14,158 100,000 SH   SOLE   100,000 0 0
ARQULE INC COM 04269E107 2,202 200,000 SH   SOLE   200,000 0 0
ARVINAS INC COM 04335A105 4,948 225,000 SH   SOLE   225,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 25,909 225,000 SH   SOLE   225,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104 21,888 850,000 SH   SOLE   850,000 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 9,475 2,500,000 SH   SOLE   2,500,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 4,379 100,000 SH   SOLE   100,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 35,374 375,000 SH   SOLE   375,000 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 7,160 1,000,000 SH   SOLE   1,000,000 0 0
CHIASMA INC COM 16706W102 2,988 400,000 SH   SOLE   400,000 0 0
COHERUS BIOSCIENCES INC COM 19249H103 3,868 175,000 SH   SOLE   175,000 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 3,701 235,000 SH   SOLE   235,000 0 0
EPIZYME INC COM 29428V104 5,836 465,000 SH   SOLE   465,000 0 0
HOMOLOGY MEDICINES INC COM 438083107 2,446 125,000 SH   SOLE   125,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 18,096 1,450,000 SH   SOLE   1,450,000 0 0
INVESCO CURNCYSHS SWISS FRAN SWISS FRANC 46138R108 8,751 92,200 SH   SOLE   92,200 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 15,780 300,000 SH   SOLE   300,000 0 0
IMMUNOMEDICS INC COM 452907108 8,322 600,000 SH   SOLE   600,000 0 0
IMMUNOMEDICS INC COM 452907108 11,096 800,000 SH Call SOLE   800,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 3,678 150,000 SH   SOLE   150,000 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 6,645 300,000 SH   SOLE   300,000 0 0
KADMON HLDGS INC COM 48283N106 4,326 2,100,000 SH   SOLE   2,100,000 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107 6,516 240,000 SH   SOLE   240,000 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 6,225 500,000 SH   SOLE   500,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 34,505 335,000 SH   SOLE   335,000 0 0
ODONATE THERAPEUTICS INC COM 676079106 2,385 65,000 SH   SOLE   65,000 0 0
SPARK THERAPEUTICS INC COM 84652J103 5,119 50,000 SH   SOLE   50,000 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 3,399 242,950 SH   SOLE   242,950 0 0
PFIZER INC COM 717081103 6,498 150,000 SH Put SOLE   150,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 2,422 200,000 SH   SOLE   200,000 0 0
INVESCO QQQ TR UNIT SER 1 46090E103 37,348 200,000 SH Put SOLE   200,000 0 0
UNIQURE NV SHS N90064101 2,735 35,000 SH   SOLE   35,000 0 0
RA PHARMACEUTICALS INC COM 74933V108 9,021 300,000 SH   SOLE   300,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 6,900 460,000 SH   SOLE   460,000 0 0
SAGE THERAPEUTICS INC COM 78667J108 5,493 30,000 SH   SOLE   30,000 0 0
SOLID BIOSCIENCES INC COM 83422E105 575 100,000 SH   SOLE   100,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 44,066 290,000 SH   SOLE   290,000 0 0
VIEWRAY INC COM 92672L107 6,608 750,000 SH   SOLE   750,000 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 43,855 500,000 SH Put SOLE   500,000 0 0
ZYMEWORKS INC COM 98985W102 6,050 275,000 SH   SOLE   275,000 0 0