The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 12,737 425,700 SH   SOLE   425,700 0 0
AKERO THERAPEUTICS INC COM 00973Y108 25,835 1,164,002 SH   SOLE   1,164,002 0 0
ALLAKOS INC COM 01671P100 289,277 3,033,526 SH   SOLE   3,033,526 0 0
AMEDISYS INC COM 023436108 30,223 181,065 SH   SOLE   181,065 0 0
AMICUS THERAPEUTICS INC COM 03152W109 245,545 25,209,964 SH   SOLE   25,209,964 0 0
ANTHEM INC COM 036752103 30,445 100,800 SH   SOLE   100,800 0 0
APREA THERAPEUTICS INC COM 03836J102 104,111 2,268,718 SH   SOLE   2,268,718 0 0
ARDELYX INC COM 039697107 30,020 4,000,000 SH   SOLE   4,000,000 0 0
ARGENX SE SPONSORED ADR 04016X101 185,117 1,153,232 SH   SOLE   1,153,232 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 76,562 4,648,570 SH   SOLE   4,648,570 0 0
ATRECA INC CL A COM 04965G109 17,586 1,136,806 SH   SOLE   1,136,806 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 38,243 639,095 SH   SOLE   639,095 0 0
AXONICS MODULATION TECH INC COM 05465P101 42,452 1,532,000 SH   SOLE   1,532,000 0 0
BIOGEN INC COM 09062X103 135,754 457,500 SH   SOLE   457,500 0 0
BIONTECH SE SPONSORED ADS 09075V102 5,878 173,500 SH   SOLE   173,500 0 0
BOSTON SCIENTIFIC CORP COM 101137107 73,763 1,631,200 SH   SOLE   1,631,200 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 115,593 1,800,800 SH   SOLE   1,800,800 0 0
CABALETTA BIO INC COM 12674W109 20,001 1,431,696 SH   SOLE   1,431,696 0 0
CASTLIGHT HEALTH INC CL B 14862Q100 14 10,229 SH   SOLE   10,229 0 0
CENTENE CORP DEL COM 15135B101 97,612 1,552,598 SH   SOLE   1,552,598 0 0
CIGNA CORP NEW COM 125523100 30,162 147,500 SH   SOLE   147,500 0 0
CRYOPORT INC COM PAR $0.001 229050307 13,865 842,363 SH   SOLE   842,363 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 5,515 2,813,565 SH   SOLE   2,813,565 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 293,119 4,709,498 SH   SOLE   4,709,498 0 0
EIDOS THERAPEUTICS INC COM 28249H104 40,241 701,178 SH   SOLE   701,178 0 0
ENDOLOGIX INC COM NEW 29266S304 124 78,755 SH   SOLE   78,755 0 0
EPIZYME INC COM 29428V104 215,152 8,746,033 SH   SOLE   8,746,033 0 0
FATE THERAPEUTICS INC COM 31189P102 219,513 11,216,809 SH   SOLE   11,216,809 0 0
FORTY SEVEN INC COM 34983P104 109,088 2,770,842 SH   SOLE   2,770,842 0 0
G1 THERAPEUTICS INC COM 3621LQ109 16,221 613,734 SH   SOLE   613,734 0 0
GENMAB A S SPONSORED ADS 372303206 20,917 936,700 SH   SOLE   936,700 0 0
GLYCOMIMETICS INC COM 38000Q102 7,109 1,343,845 SH   SOLE   1,343,845 0 0
GOSSAMER BIO INC COM 38341P102 4,068 260,300 SH   SOLE   260,300 0 0
GRITSTONE ONCOLOGY INC COM 39868T105 27,956 3,116,594 SH   SOLE   3,116,594 0 0
GUARDANT HEALTH INC COM 40131M109 30,451 389,700 SH   SOLE   389,700 0 0
HCA HEALTHCARE INC COM 40412C101 42,155 285,200 SH   SOLE   285,200 0 0
HOOKIPA PHARMA INC COM 43906K100 23,146 1,892,521 SH   SOLE   1,892,521 0 0
IGM BIOSCIENCES INC COM 449585108 119,975 3,144,000 SH   SOLE   3,144,000 0 0
IMMUNOGEN INC COM 45253H101 74,737 14,639,960 SH   SOLE   14,639,960 0 0
KRYSTAL BIOTECH INC COM 501147102 60,375 1,090,200 SH   SOLE   1,090,200 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 63,880 3,237,700 SH   SOLE   3,237,700 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 23,665 1,920,831 SH   SOLE   1,920,831 0 0
NEVRO CORP COM 64157F103 110,389 939,164 SH   SOLE   939,164 0 0
NOVARTIS A G SPONSORED ADR 66987V109 54,267 573,100 SH   SOLE   573,100 0 0
ODONATE THERAPEUTICS INC COM 676079106 25,638 790,071 SH   SOLE   790,071 0 0
OVID THERAPEUTICS INC COM 690469101 506 121,950 SH   SOLE   121,950 0 0
PRA HEALTH SCIENCES INC COM 69354M108 49,995 449,800 SH   SOLE   449,800 0 0
PRINCIPIA BIOPHARMA INC COM 74257L108 149,132 2,722,388 SH   SOLE   2,722,388 0 0
PTC THERAPEUTICS INC COM 69366J200 41,283 859,526 SH   SOLE   859,526 0 0
REGENXBIO INC COM 75901B107 102,769 2,508,386 SH   SOLE   2,508,386 0 0
REPLIMUNE GROUP INC COM 76029N106 39,698 2,766,407 SH   SOLE   2,766,407 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 38,761 2,940,889 SH   SOLE   2,940,889 0 0
SHOCKWAVE MED INC COM 82489T104 24,942 567,900 SH   SOLE   567,900 0 0
STEREOTAXIS INC COM NEW 85916J409 16,766 3,169,308 SH   SOLE   3,169,308 0 0
STOKE THERAPEUTICS INC COM 86150R107 28,908 1,020,778 SH   SOLE   1,020,778 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 1,467 212,291 SH   SOLE   212,291 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 69,877 1,172,232 SH   SOLE   1,172,232 0 0
TCR2 THERAPEUTICS INC COM 87808K106 25,692 1,799,188 SH   SOLE   1,799,188 0 0
TRICIDA INC COM 89610F101 80,352 2,129,100 SH   SOLE   2,129,100 0 0
UNIQURE NV SHS N90064101 182,971 2,553,325 SH   SOLE   2,553,325 0 0
UNITEDHEALTH GROUP INC COM 91324P102 59,707 203,100 SH   SOLE   203,100 0 0
VAPOTHERM INC COM 922107107 11,668 959,539 SH   SOLE   959,539 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 26,662 3,326,493 SH   SOLE   3,326,493 0 0
XERIS PHARMACEUTICALS INC COM 98422L107 21,155 3,000,641 SH   SOLE   3,000,641 0 0