The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100 28,031 322,713 SH   DFND   0 322,713 0
ABBVIE INC COM 00287Y109 14,719 166,239 SH   DFND   0 166,239 0
ACORDA THERAPEUTICS INC COM 00484M106 3,863 1,893,400 SH   DFND   0 1,893,400 0
AERIE PHARMACEUTICALS INC COM 00771V108 58,333 2,413,464 SH   DFND   0 2,413,464 0
ALEXION PHARMACEUTICALS INC COM 015351109 116,417 1,076,442 SH   DFND   0 1,076,442 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 9,420 44,411 SH   DFND   0 44,411 0
ALLERGAN PLC SHS G0177J108 53,824 281,548 SH   DFND   0 281,548 0
AMARIN CORP PLC SPONS ADR NEW 023111206 11,437 533,421 SH   DFND   0 533,421 0
ANTHEM INC COM 036752103 59,967 198,548 SH   DFND   0 198,548 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 48,627 1,070,616 SH   DFND   0 1,070,616 0
AUDENTES THERAPEUTICS INC COM 05070R104 73,775 1,232,873 SH   DFND   0 1,232,873 0
AXONICS MODULATION TECH INC COM 05465P101 15,241 550,026 SH   DFND   0 550,026 0
BIOGEN INC COM 09062X103 8,991 30,300 SH Call DFND   0 30,300 0
BIOGEN INC COM 09062X103 67,752 228,328 SH   DFND   0 228,328 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 46,810 553,634 SH   DFND   0 553,634 0
BIOMARIN PHARMACEUTICAL INC NOTE 1.500%10/1 09061GAF8 19,842 18,275,000 PRN   DFND   0 18,275,000 0
BLUEPRINT MEDICINES CORP COM 09627Y109 26,981 336,800 SH Put DFND   0 336,800 0
CARDIOVASCULAR SYS INC DEL COM 141619106 13,347 274,689 SH   DFND   0 274,689 0
CATALENT INC COM 148806102 17,845 316,962 SH   DFND   0 316,962 0
CENTENE CORP DEL COM 15135B101 51,505 819,229 SH   DFND   0 819,229 0
CIGNA CORP NEW COM 125523100 106,233 519,500 SH Call DFND   0 519,500 0
CIGNA CORP NEW COM 125523100 54,336 265,717 SH   DFND   0 265,717 0
COHERUS BIOSCIENCES INC COM 19249H103 9,634 535,086 SH   DFND   0 535,086 0
COUPA SOFTWARE INC COM 22266L106 1,423 9,731 SH   DFND   0 9,731 0
DERMIRA INC COM 24983L104 34,431 2,271,180 SH   DFND   0 2,271,180 0
DERMIRA INC NOTE 3.000% 5/1 24983LAB0 28,270 30,558,000 PRN   DFND   0 30,558,000 0
EDWARDS LIFESCIENCES CORP COM 28176E108 24,094 103,279 SH   DFND   0 103,279 0
ENDOLOGIX INC COM NEW 29266S304 252 159,285 SH   DFND   0 159,285 0
ENVISTA HLDGS CORP COM 29415F104 24,475 825,732 SH   DFND   0 825,732 0
EXACT SCIENCES CORP COM 30063P105 19,406 209,839 SH   DFND   0 209,839 0
FLUIDIGM CORP DEL COM 34385P108 11,258 3,234,984 SH   DFND   0 3,234,984 0
GILEAD SCIENCES INC COM 375558103 196,513 3,024,200 SH Call DFND   0 3,024,200 0
GILEAD SCIENCES INC COM 375558103 87,836 1,351,736 SH   DFND   0 1,351,736 0
HALOZYME THERAPEUTICS INC COM 40637H109 10,522 593,480 SH   DFND   0 593,480 0
HCA HEALTHCARE INC COM 40412C101 41,300 279,411 SH   DFND   0 279,411 0
HUMANA INC COM 444859102 29,155 79,546 SH   DFND   0 79,546 0
ICON PLC SHS G4705A100 33,340 193,577 SH   DFND   0 193,577 0
ICU MED INC COM 44930G107 30,999 165,665 SH   DFND   0 165,665 0
IMMUNOMEDICS INC COM 452907108 31,724 1,499,239 SH   DFND   0 1,499,239 0
INTUIT COM 461202103 4,387 16,747 SH   DFND   0 16,747 0
IQVIA HLDGS INC COM 46266C105 53,085 343,567 SH   DFND   0 343,567 0
IRHYTHM TECHNOLOGIES INC COM 450056106 31,202 458,241 SH   DFND   0 458,241 0
KARUNA THERAPEUTICS INC COM 48576A100 45,396 602,551 SH   DFND   0 602,551 0
MICROCHIP TECHNOLOGY INC COM 595017104 8,553 81,671 SH   DFND   0 81,671 0
MICROSOFT CORP COM 594918104 11,255 71,367 SH   DFND   0 71,367 0
MOLINA HEALTHCARE INC COM 60855R100 24,012 176,964 SH   DFND   0 176,964 0
MORPHOSYS AG SPONSORED ADS D55040105 15,504 122,275 SH   DFND   0 122,275 0
NEVRO CORP COM 64157F103 67,840 577,163 SH   DFND   0 577,163 0
NOVARTIS A G SPONSORED ADR 66987V109 40,679 442,640 SH   DFND   0 442,640 0
NVIDIA CORP COM 67066G104 9,386 39,889 SH   DFND   0 39,889 0
NXP SEMICONDUCTORS N V COM N6596X109 7,922 62,249 SH   DFND   0 62,249 0
PAYPAL HLDGS INC COM 70450Y103 2,063 19,076 SH   DFND   0 19,076 0
PENUMBRA INC COM 70975L107 68,795 418,792 SH   DFND   0 418,792 0
PFIZER INC COM 717081103 36,168 923,126 SH   DFND   0 923,126 0
SALESFORCE COM INC COM 79466L302 10,311 63,398 SH   DFND   0 63,398 0
SQUARE INC CL A 852234103 5,032 80,427 SH   DFND   0 80,427 0
UNITEDHEALTH GROUP INC COM 91324P102 27,840 94,699 SH   DFND   0 94,699 0
VERTEX PHARMACEUTICALS INC COM 92532F100 27,631 126,200 SH Call DFND   0 126,200 0
VERTEX PHARMACEUTICALS INC COM 92532F100 12,463 56,922 SH   DFND   0 56,922 0
VISTEON CORP COM NEW 92839U206 1,759 20,313 SH   DFND   0 20,313 0
ZIMMER BIOMET HLDGS INC COM 98956P102 66,252 442,627 SH   DFND   0 442,627 0