The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U | COM | 90214J101 | 19,123 | 797,137 | SH | DFND | 1 | 797,137 | 0 | 0 | |
| 2U | COM | 90214J101 | 6,532 | 272,299 | SH | SOLE | 0 | 272,299 | 0 | 0 | |
| 2U | COM | 90214J101 | 265 | 11,056 | SH | DFND | 3 | 11,056 | 0 | 0 | |
| 2U | COM | 90214J101 | 21,096 | 879,385 | SH | DFND | 2 | 879,385 | 0 | 0 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 36,690 | 566,817 | SH | DFND | 1 | 566,817 | 0 | 0 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 90,988 | 1,405,652 | SH | SOLE | 0 | 1,300,965 | 0 | 104,687 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 25,877 | 399,768 | SH | DFND | 3 | 261,855 | 0 | 137,913 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 134,183 | 2,072,972 | SH | DFND | 2 | 1,849,787 | 0 | 223,185 | |
| AJ Gallagher & Co | COM | 363576109 | 55,329 | 581,003 | SH | DFND | 3 | 386,227 | 0 | 194,776 | |
| AJ Gallagher & Co | COM | 363576109 | 91,637 | 962,274 | SH | DFND | 1 | 962,274 | 0 | 0 | |
| AJ Gallagher & Co | COM | 363576109 | 295,603 | 3,104,093 | SH | DFND | 2 | 2,776,125 | 0 | 327,968 | |
| AJ Gallagher & Co | COM | 363576109 | 201,818 | 2,119,272 | SH | SOLE | 0 | 1,967,067 | 0 | 152,205 | |
| Abiomed | COM | 003654100 | 126,089 | 739,137 | SH | DFND | 1 | 739,137 | 0 | 0 | |
| Abiomed | COM | 003654100 | 100,472 | 588,967 | SH | SOLE | 0 | 558,183 | 0 | 30,784 | |
| Abiomed | COM | 003654100 | 212,707 | 1,246,888 | SH | DFND | 2 | 1,169,662 | 0 | 77,226 | |
| Abiomed | COM | 003654100 | 24,717 | 144,889 | SH | DFND | 3 | 98,146 | 0 | 46,743 | |
| Acacia Research Corp | ACACIA TCH COM | 003881307 | 382 | 143,640 | SH | DFND | 1 | 143,640 | 0 | 0 | |
| Acacia Research Corp | ACACIA TCH COM | 003881307 | 591 | 222,180 | SH | SOLE | 0 | 222,180 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 587 | 9,871 | SH | DFND | 3 | 9,871 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 55,997 | 942,396 | SH | DFND | 2 | 842,636 | 0 | 99,760 | |
| Activision Blizzard Inc | COM | 00507V109 | 41,412 | 696,939 | SH | DFND | 1 | 696,939 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 11,927 | 200,716 | SH | SOLE | 0 | 200,716 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 1,392 | 1,160,156 | SH | DFND | 2 | 402,147 | 0 | 758,009 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 2,443 | 2,035,855 | SH | DFND | 1 | 2,035,855 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 469 | 390,837 | SH | DFND | 3 | 390,837 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 841 | 700,697 | SH | SOLE | 0 | 700,697 | 0 | 0 | |
| Aduro Biotechnology | COM | 00739L101 | 1,471 | 1,246,208 | SH | DFND | 2 | 421,520 | 0 | 824,688 | |
| Aduro Biotechnology | COM | 00739L101 | 2,338 | 1,980,937 | SH | DFND | 1 | 1,980,937 | 0 | 0 | |
| Aduro Biotechnology | COM | 00739L101 | 495 | 419,818 | SH | DFND | 3 | 419,818 | 0 | 0 | |
| Aduro Biotechnology | COM | 00739L101 | 691 | 585,293 | SH | SOLE | 0 | 585,293 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 17,887 | 289,717 | SH | DFND | 1 | 289,717 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 14,175 | 229,594 | SH | DFND | 2 | 80,861 | 0 | 148,733 | |
| Aerovironment | COM | 008073108 | 4,804 | 77,817 | SH | DFND | 3 | 77,817 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 13,618 | 220,567 | SH | SOLE | 0 | 220,567 | 0 | 0 | |
| Agios Pharmaceuticals | COM | 00847X104 | 82 | 1,709 | SH | DFND | 3 | 1,709 | 0 | 0 | |
| Albemarle Corp | COM | 012653101 | 143,490 | 1,964,535 | SH | DFND | 2 | 1,759,032 | 0 | 205,503 | |
| Albemarle Corp | COM | 012653101 | 49,435 | 676,823 | SH | DFND | 1 | 676,823 | 0 | 0 | |
| Albemarle Corp | COM | 012653101 | 26,501 | 362,834 | SH | DFND | 3 | 240,657 | 0 | 122,177 | |
| Albemarle Corp | COM | 012653101 | 104,945 | 1,436,815 | SH | SOLE | 0 | 1,341,731 | 0 | 95,084 | |
| Alector Inc | COM | 014442107 | 36 | 2,072 | SH | DFND | 3 | 2,072 | 0 | 0 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 810,357 | 3,820,635 | SH | DFND | 1 | 3,820,635 | 0 | 0 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 7,503,110 | 35,375,344 | SH | DFND | 2 | 23,995,112 | 0 | 11,380,232 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 629,122 | 2,966,158 | SH | DFND | 3 | 932,378 | 0 | 2,033,780 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 2,023,095 | 9,538,400 | SH | SOLE | 0 | 7,975,244 | 0 | 1,563,156 | |
| Align Technology Inc | COM | 016255101 | 12,592 | 45,125 | SH | DFND | 2 | 45,125 | 0 | 0 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 209,030 | 1,814,972 | SH | DFND | 1 | 1,814,972 | 0 | 0 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 261,659 | 2,271,939 | SH | SOLE | 0 | 2,166,284 | 0 | 105,655 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 68,503 | 594,797 | SH | DFND | 3 | 458,875 | 0 | 135,922 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 403,673 | 3,505,015 | SH | DFND | 2 | 2,924,448 | 0 | 580,567 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 6,429 | 4,800 | SH | DFND | 3 | 3,165 | 0 | 1,635 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 53,829 | 40,189 | SH | DFND | 2 | 37,296 | 0 | 2,893 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 28,887 | 21,567 | SH | DFND | 1 | 21,567 | 0 | 0 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 101,761 | 75,976 | SH | SOLE | 0 | 75,976 | 0 | 0 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 508,822 | 380,564 | SH | DFND | 1 | 380,564 | 0 | 0 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 882,304 | 659,903 | SH | SOLE | 0 | 525,338 | 0 | 134,565 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 187,413 | 140,172 | SH | DFND | 3 | 91,681 | 0 | 48,491 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 1,784,347 | 1,334,570 | SH | DFND | 2 | 820,034 | 0 | 514,536 | |
| Amazon.Com | COM | 023135106 | 916,118 | 495,778 | SH | DFND | 1 | 495,778 | 0 | 0 | |
| Amazon.Com | COM | 023135106 | 4,790,813 | 2,592,656 | SH | DFND | 2 | 1,798,203 | 0 | 794,453 | |
| Amazon.Com | COM | 023135106 | 297,643 | 161,076 | SH | DFND | 3 | 103,648 | 0 | 57,428 | |
| Amazon.Com | COM | 023135106 | 2,297,974 | 1,243,600 | SH | SOLE | 0 | 1,054,140 | 0 | 189,460 | |
| Ambarella | SHS | G037AX101 | 8,933 | 147,500 | SH | DFND | 1 | 147,500 | 0 | 0 | |
| Ambarella | SHS | G037AX101 | 7,541 | 124,522 | SH | DFND | 2 | 43,905 | 0 | 80,617 | |
| Ambarella | SHS | G037AX101 | 5,911 | 97,605 | SH | SOLE | 0 | 97,605 | 0 | 0 | |
| Ambarella | SHS | G037AX101 | 2,617 | 43,218 | SH | DFND | 3 | 43,218 | 0 | 0 | |
| Ambev ADR | SPONSORED ADR | 02319V103 | 11 | 2,458 | SH | DFND | 3 | 2,458 | 0 | 0 | |
| Ameren | COM | 023608102 | 545 | 7,100 | SH | DFND | 1 | 7,100 | 0 | 0 | |
| American Express | COM | 025816109 | 18,463 | 148,313 | SH | DFND | 2 | 148,313 | 0 | 0 | |
| Analog Devices | COM | 032654105 | 16,191 | 136,240 | SH | DFND | 1 | 136,240 | 0 | 0 | |
| Analog Devices | COM | 032654105 | 1,059 | 8,915 | SH | DFND | 2 | 0 | 0 | 8,915 | |
| Analog Devices | COM | 032654105 | 20 | 170 | SH | DFND | 3 | 170 | 0 | 0 | |
| Analog Devices | COM | 032654105 | 19,477 | 163,895 | SH | SOLE | 0 | 163,895 | 0 | 0 | |
| Anaplan Inc Common | COM | 03272L108 | 98,074 | 1,871,644 | SH | SOLE | 0 | 1,871,644 | 0 | 0 | |
| Annaly Capital Man. | COM | 035710409 | 167 | 17,762 | SH | DFND | 1 | 17,762 | 0 | 0 | |
| Anthem Inc | COM | 036752103 | 161,794 | 535,687 | SH | DFND | 1 | 535,687 | 0 | 0 | |
| Anthem Inc | COM | 036752103 | 583,129 | 1,930,699 | SH | DFND | 2 | 1,724,420 | 0 | 206,279 | |
| Anthem Inc | COM | 036752103 | 111,745 | 369,979 | SH | DFND | 3 | 245,955 | 0 | 124,024 | |
| Anthem Inc | COM | 036752103 | 392,922 | 1,300,938 | SH | SOLE | 0 | 1,204,113 | 0 | 96,825 | |
| Apache Corp | COM | 037411105 | 57,547 | 2,248,813 | SH | DFND | 1 | 2,248,813 | 0 | 0 | |
| Apache Corp | COM | 037411105 | 203,801 | 7,964,093 | SH | DFND | 2 | 7,112,728 | 0 | 851,365 | |
| Apache Corp | COM | 037411105 | 136,556 | 5,336,298 | SH | SOLE | 0 | 4,934,666 | 0 | 401,632 | |
| Apache Corp | COM | 037411105 | 28,776 | 1,124,501 | SH | DFND | 3 | 607,569 | 0 | 516,932 | |
| Apollo Commercial Real Estate Finance REIT | COM | 03762U105 | 221 | 12,100 | SH | DFND | 1 | 12,100 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 47,749 | 1,249,645 | SH | DFND | 1 | 1,249,645 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 6,238 | 163,267 | SH | DFND | 3 | 163,267 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 52,070 | 1,362,723 | SH | DFND | 2 | 1,080,568 | 0 | 282,155 | |
| Appian Corp | CL A | 03782L101 | 30,679 | 802,905 | SH | SOLE | 0 | 802,905 | 0 | 0 | |
| Apple | COM | 037833100 | 909 | 3,096 | SH | DFND | 2 | 0 | 0 | 3,096 | |
| Apple | COM | 037833100 | 12,147 | 41,367 | SH | DFND | 1 | 41,367 | 0 | 0 | |
| Apple | COM | 037833100 | 16 | 53 | SH | DFND | 3 | 53 | 0 | 0 | |
| Apple | COM | 037833100 | 14,816 | 50,456 | SH | SOLE | 0 | 50,456 | 0 | 0 | |
| Atlassian Corp Plc | CL A | G06242104 | 42,391 | 352,259 | SH | DFND | 3 | 217,588 | 0 | 134,671 | |
| Atlassian Corp Plc | CL A | G06242104 | 592,621 | 4,924,558 | SH | DFND | 2 | 1,722,802 | 0 | 3,201,756 | |
| Atlassian Corp Plc | CL A | G06242104 | 87,909 | 730,503 | SH | DFND | 1 | 730,503 | 0 | 0 | |
| Atlassian Corp Plc | CL A | G06242104 | 190,897 | 1,586,311 | SH | SOLE | 0 | 822,674 | 0 | 763,637 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 22,263 | 278,251 | SH | DFND | 3 | 183,728 | 0 | 94,523 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 117,276 | 1,465,761 | SH | DFND | 2 | 1,308,376 | 0 | 157,385 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 33,681 | 420,965 | SH | DFND | 1 | 420,965 | 0 | 0 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 82,672 | 1,033,274 | SH | SOLE | 0 | 960,077 | 0 | 73,197 | |
| Axogen Inc | COM | 05463X106 | 6,424 | 359,100 | SH | DFND | 1 | 359,100 | 0 | 0 | |
| Axogen Inc | COM | 05463X106 | 6,693 | 374,100 | SH | DFND | 2 | 131,200 | 0 | 242,900 | |
| Axogen Inc | COM | 05463X106 | 2,306 | 128,917 | SH | DFND | 3 | 128,917 | 0 | 0 | |
| Axogen Inc | COM | 05463X106 | 3,034 | 169,600 | SH | SOLE | 0 | 169,600 | 0 | 0 | |
| Axon Enterprise Inc | COM | 05464C101 | 48,376 | 660,157 | SH | DFND | 1 | 660,157 | 0 | 0 | |
| Axon Enterprise Inc | COM | 05464C101 | 137,912 | 1,881,991 | SH | DFND | 2 | 1,574,571 | 0 | 307,420 | |
| Axon Enterprise Inc | COM | 05464C101 | 28,803 | 393,060 | SH | DFND | 3 | 284,199 | 0 | 108,861 | |
| Axon Enterprise Inc | COM | 05464C101 | 91,872 | 1,253,710 | SH | SOLE | 0 | 1,169,340 | 0 | 84,370 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 9,887 | 78,220 | SH | DFND | 1 | 78,220 | 0 | 0 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 622,130 | 4,921,917 | SH | DFND | 2 | 4,405,567 | 0 | 516,350 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 23,176 | 183,358 | SH | DFND | 3 | 12,315 | 0 | 171,043 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 939 | 7,428 | SH | SOLE | 0 | 7,428 | 0 | 0 | |
| BanColombia Pref ADR | SPON ADR PREF | 05968L102 | 14,090 | 257,155 | SH | DFND | 2 | 0 | 0 | 257,155 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 203,346 | 22,720,251 | SH | DFND | 2 | 10,673,124 | 0 | 12,047,127 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 31,505 | 3,520,071 | SH | DFND | 1 | 3,520,071 | 0 | 0 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 24,156 | 2,698,968 | SH | DFND | 3 | 2,605,654 | 0 | 93,314 | |
| Banco Macro ADR | SPON ADR B | 05961W105 | 3,989 | 110,039 | SH | DFND | 1 | 110,039 | 0 | 0 | |
| Banco Macro ADR | SPON ADR B | 05961W105 | 23,432 | 646,399 | SH | DFND | 2 | 310,120 | 0 | 336,279 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 17,610 | 531,708 | SH | DFND | 1 | 531,708 | 0 | 0 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 13,772 | 415,835 | SH | DFND | 2 | 146,289 | 0 | 269,546 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 4,719 | 142,474 | SH | DFND | 3 | 142,474 | 0 | 0 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 9,741 | 294,100 | SH | SOLE | 0 | 294,100 | 0 | 0 | |
| Beigene Ltd | SPONSORED ADR | 07725L102 | 8,785 | 52,999 | SH | DFND | 1 | 52,999 | 0 | 0 | |
| Beigene Ltd | SPONSORED ADR | 07725L102 | 39,066 | 235,676 | SH | DFND | 2 | 115,933 | 0 | 119,743 | |
| Benefitfocus Inc | COM | 08180D106 | 5,854 | 266,817 | SH | DFND | 2 | 74,720 | 0 | 192,097 | |
| Benefitfocus Inc | COM | 08180D106 | 6,723 | 306,448 | SH | DFND | 1 | 306,448 | 0 | 0 | |
| Benefitfocus Inc | COM | 08180D106 | 2,249 | 102,529 | SH | DFND | 3 | 102,529 | 0 | 0 | |
| Benefitfocus Inc | COM | 08180D106 | 4,967 | 226,368 | SH | SOLE | 0 | 226,368 | 0 | 0 | |
| BitAuto Holdings Ltd - ADR | SPONSORED ADS | 091727107 | 249 | 16,750 | SH | SOLE | 0 | 16,750 | 0 | 0 | |
| BlackRock Floating Rate Income | COM | 091941104 | 10,139 | 787,770 | SH | DFND | 1 | 787,770 | 0 | 0 | |
| Blackline | COM | 09239B109 | 13,545 | 262,705 | SH | DFND | 1 | 262,705 | 0 | 0 | |
| Blackline | COM | 09239B109 | 10,935 | 212,077 | SH | DFND | 2 | 74,552 | 0 | 137,525 | |
| Blackline | COM | 09239B109 | 3,728 | 72,304 | SH | DFND | 3 | 72,304 | 0 | 0 | |
| Blackline | COM | 09239B109 | 7,176 | 139,175 | SH | SOLE | 0 | 139,175 | 0 | 0 | |
| Blue Apron Holdings Inc | CL A | 09523Q101 | 977 | 148,506 | SH | DFND | 1 | 148,506 | 0 | 0 | |
| Blue Capital Reinsurance Holdings Fund (USD) | COM | G1190F107 | 4,242 | 618,438 | SH | DFND | 1 | 618,438 | 0 | 0 | |
| Bluebird Bio Inc | COM | 09609G100 | 53 | 608 | SH | DFND | 3 | 608 | 0 | 0 | |
| Bluebird Bio Inc | COM | 09609G100 | 60,986 | 695,000 | SH | SOLE | 0 | 695,000 | 0 | 0 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 4,162 | 98,030 | SH | DFND | 1 | 98,030 | 0 | 0 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 229 | 5,401 | SH | DFND | 2 | 0 | 0 | 5,401 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 6 | 148 | SH | DFND | 3 | 148 | 0 | 0 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 4,926 | 116,021 | SH | SOLE | 0 | 116,021 | 0 | 0 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 58,107 | 470,351 | SH | DFND | 1 | 470,351 | 0 | 0 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 206,524 | 1,671,716 | SH | DFND | 2 | 1,494,504 | 0 | 177,212 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 39,686 | 321,237 | SH | DFND | 3 | 214,255 | 0 | 106,982 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 139,738 | 1,131,119 | SH | SOLE | 0 | 1,047,554 | 0 | 83,565 | |
| CEVA Inc | COM | 157210105 | 4,232 | 156,980 | SH | DFND | 1 | 156,980 | 0 | 0 | |
| CEVA Inc | COM | 157210105 | 3,979 | 147,595 | SH | DFND | 2 | 51,655 | 0 | 95,940 | |
| CEVA Inc | COM | 157210105 | 1,459 | 54,100 | SH | DFND | 3 | 54,100 | 0 | 0 | |
| CEVA Inc | COM | 157210105 | 2,224 | 82,500 | SH | SOLE | 0 | 82,500 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 17,982 | 229,951 | SH | DFND | 1 | 229,951 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 1,204 | 15,400 | SH | DFND | 2 | 0 | 0 | 15,400 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 21,655 | 276,923 | SH | SOLE | 0 | 276,923 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 23 | 289 | SH | DFND | 3 | 289 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 5,402 | 61,618 | SH | DFND | 1 | 61,618 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 2,885 | 32,903 | SH | DFND | 3 | 20,331 | 0 | 12,572 | |
| CarMax Inc | COM | 143130102 | 25,056 | 285,799 | SH | DFND | 2 | 285,799 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 2,412 | 27,510 | SH | SOLE | 0 | 27,510 | 0 | 0 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 27,731 | 7,336,322 | SH | DFND | 1 | 7,336,322 | 0 | 0 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 89,833 | 23,765,326 | SH | DFND | 2 | 9,005,588 | 0 | 14,759,738 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 4,503 | 1,191,205 | SH | SOLE | 0 | 1,191,205 | 0 | 0 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 33,540 | 8,873,124 | SH | DFND | 3 | 349,678 | 0 | 8,523,446 | |
| Chegg | COM | 163092109 | 167,428 | 4,416,454 | SH | DFND | 1 | 4,416,454 | 0 | 0 | |
| Chegg | COM | 163092109 | 225,989 | 5,961,205 | SH | DFND | 2 | 5,218,160 | 0 | 743,045 | |
| Chegg | COM | 163092109 | 34,514 | 910,417 | SH | DFND | 3 | 699,597 | 0 | 210,820 | |
| Chegg | COM | 163092109 | 121,556 | 3,206,445 | SH | SOLE | 0 | 3,087,231 | 0 | 119,214 | |
| Chewy Inc | CL A | 16679L109 | 64,966 | 2,240,191 | SH | DFND | 1 | 2,240,191 | 0 | 0 | |
| Chewy Inc | CL A | 16679L109 | 65,539 | 2,259,964 | SH | DFND | 2 | 2,259,964 | 0 | 0 | |
| Chewy Inc | CL A | 16679L109 | 20,243 | 698,020 | SH | SOLE | 0 | 698,020 | 0 | 0 | |
| Chewy Inc | CL A | 16679L109 | 888 | 30,634 | SH | DFND | 3 | 30,634 | 0 | 0 | |
| Chipotle Mexican Grill | COM | 169656105 | 52,143 | 62,289 | SH | DFND | 1 | 62,289 | 0 | 0 | |
| Chipotle Mexican Grill | COM | 169656105 | 184,242 | 220,093 | SH | DFND | 2 | 196,895 | 0 | 23,198 | |
| Chipotle Mexican Grill | COM | 169656105 | 34,970 | 41,775 | SH | DFND | 3 | 27,687 | 0 | 14,088 | |
| Chipotle Mexican Grill | COM | 169656105 | 119,301 | 142,515 | SH | SOLE | 0 | 131,897 | 0 | 10,618 | |
| CoStar Group | COM | 22160N109 | 97,158 | 162,390 | SH | DFND | 1 | 162,390 | 0 | 0 | |
| CoStar Group | COM | 22160N109 | 32,206 | 53,829 | SH | SOLE | 0 | 53,829 | 0 | 0 | |
| CoStar Group | COM | 22160N109 | 1,362 | 2,276 | SH | DFND | 3 | 2,276 | 0 | 0 | |
| CoStar Group | COM | 22160N109 | 114,896 | 192,037 | SH | DFND | 2 | 192,037 | 0 | 0 | |
| Coca Cola | COM | 191216100 | 36 | 649 | SH | DFND | 3 | 649 | 0 | 0 | |
| Coca Cola | COM | 191216100 | 1,816 | 32,801 | SH | DFND | 2 | 0 | 0 | 32,801 | |
| Coca Cola | COM | 191216100 | 28,540 | 515,629 | SH | DFND | 1 | 515,629 | 0 | 0 | |
| Coca Cola | COM | 191216100 | 34,117 | 616,393 | SH | SOLE | 0 | 616,393 | 0 | 0 | |
| Codexis | COM | 192005106 | 20,011 | 1,251,484 | SH | DFND | 1 | 1,251,484 | 0 | 0 | |
| Codexis | COM | 192005106 | 19,821 | 1,239,559 | SH | DFND | 2 | 435,730 | 0 | 803,829 | |
| Codexis | COM | 192005106 | 6,775 | 423,731 | SH | DFND | 3 | 423,731 | 0 | 0 | |
| Codexis | COM | 192005106 | 13,963 | 873,260 | SH | SOLE | 0 | 873,260 | 0 | 0 | |
| Consolidated Edison | COM | 209115104 | 798 | 8,820 | SH | DFND | 1 | 8,820 | 0 | 0 | |
| Copa Holdings S A | CL A | P31076105 | 57,744 | 534,270 | SH | DFND | 3 | 21,956 | 0 | 512,314 | |
| Copa Holdings S A | CL A | P31076105 | 239,321 | 2,214,299 | SH | DFND | 2 | 1,530,363 | 0 | 683,936 | |
| Copa Holdings S A | CL A | P31076105 | 13,118 | 121,373 | SH | DFND | 1 | 121,373 | 0 | 0 | |
| Copa Holdings S A | CL A | P31076105 | 30,028 | 277,829 | SH | SOLE | 0 | 277,829 | 0 | 0 | |
| Credicorp | COM | G2519Y108 | 20,253 | 95,027 | SH | DFND | 1 | 95,027 | 0 | 0 | |
| Credicorp | COM | G2519Y108 | 311,726 | 1,462,612 | SH | DFND | 2 | 816,490 | 0 | 646,122 | |
| Credicorp | COM | G2519Y108 | 42,531 | 199,554 | SH | DFND | 3 | 8,120 | 0 | 191,434 | |
| Credicorp | COM | G2519Y108 | 25,907 | 121,553 | SH | SOLE | 0 | 121,553 | 0 | 0 | |
| Cullen/Frost Bankers | COM | 229899109 | 9,801 | 100,240 | SH | DFND | 1 | 100,240 | 0 | 0 | |
| Cullen/Frost Bankers | COM | 229899109 | 686 | 7,018 | SH | DFND | 2 | 0 | 0 | 7,018 | |
| Cullen/Frost Bankers | COM | 229899109 | 11,982 | 122,538 | SH | SOLE | 0 | 122,538 | 0 | 0 | |
| Cullen/Frost Bankers | COM | 229899109 | 13 | 128 | SH | DFND | 3 | 128 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 4,759 | 40,823 | SH | DFND | 3 | 40,823 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 12,835 | 110,100 | SH | DFND | 1 | 110,100 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 13,663 | 117,200 | SH | DFND | 2 | 41,400 | 0 | 75,800 | |
| CyberArk Software Ltd | SHS | M2862V108 | 9,385 | 80,500 | SH | SOLE | 0 | 80,500 | 0 | 0 | |
| Denali Therapeutics | COM | 24823R105 | 1,903 | 109,265 | SH | DFND | 3 | 77,488 | 0 | 31,777 | |
| Denali Therapeutics | COM | 24823R105 | 33,667 | 1,932,690 | SH | DFND | 2 | 1,932,690 | 0 | 0 | |
| Denali Therapeutics | COM | 24823R105 | 34,453 | 1,977,791 | SH | DFND | 1 | 1,977,791 | 0 | 0 | |
| Denali Therapeutics | COM | 24823R105 | 62,198 | 3,570,501 | SH | SOLE | 0 | 3,570,501 | 0 | 0 | |
| Dexcom Inc | COM | 252131107 | 51,679 | 236,259 | SH | DFND | 3 | 157,259 | 0 | 79,000 | |
| Dexcom Inc | COM | 252131107 | 665,497 | 3,042,411 | SH | DFND | 2 | 1,085,479 | 0 | 1,956,932 | |
| Dexcom Inc | COM | 252131107 | 122,578 | 560,381 | SH | DFND | 1 | 560,381 | 0 | 0 | |
| Dexcom Inc | COM | 252131107 | 213,544 | 976,248 | SH | SOLE | 0 | 527,814 | 0 | 448,434 | |
| Digimarc | COM | 25381B101 | 6,247 | 186,145 | SH | DFND | 1 | 186,145 | 0 | 0 | |
| Digimarc | COM | 25381B101 | 9,552 | 284,634 | SH | DFND | 2 | 100,343 | 0 | 184,291 | |
| Digimarc | COM | 25381B101 | 3,255 | 96,997 | SH | DFND | 3 | 96,997 | 0 | 0 | |
| Digimarc | COM | 25381B101 | 5,192 | 154,711 | SH | SOLE | 0 | 154,711 | 0 | 0 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 8,152 | 118,495 | SH | DFND | 1 | 118,495 | 0 | 0 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 565 | 8,210 | SH | DFND | 2 | 0 | 0 | 8,210 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 10 | 148 | SH | DFND | 3 | 148 | 0 | 0 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 9,820 | 142,735 | SH | SOLE | 0 | 142,735 | 0 | 0 | |
| EOG Resources | COM | 26875P101 | 309,096 | 3,690,263 | SH | DFND | 2 | 3,313,973 | 0 | 376,290 | |
| EOG Resources | COM | 26875P101 | 83,467 | 996,503 | SH | DFND | 1 | 996,503 | 0 | 0 | |
| EOG Resources | COM | 26875P101 | 41,253 | 492,509 | SH | DFND | 3 | 266,578 | 0 | 225,931 | |
| EOG Resources | COM | 26875P101 | 195,164 | 2,330,039 | SH | SOLE | 0 | 2,154,031 | 0 | 176,008 | |
| Ecolab | COM | 278865100 | 5,601 | 29,020 | SH | DFND | 1 | 29,020 | 0 | 0 | |
| Ecolab | COM | 278865100 | 427 | 2,212 | SH | DFND | 3 | 2,212 | 0 | 0 | |
| Ecolab | COM | 278865100 | 6,198 | 32,114 | SH | DFND | 2 | 20,647 | 0 | 11,467 | |
| Edwards Lifesciences Corp | COM | 28176E108 | 293 | 1,256 | SH | DFND | 3 | 1,256 | 0 | 0 | |
| Estee Lauder 'A' | COM | 518439104 | 33,942 | 164,334 | SH | DFND | 2 | 164,334 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 28,998 | 1,437,675 | SH | DFND | 2 | 1,437,675 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 27,054 | 1,341,312 | SH | DFND | 1 | 1,341,312 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 364 | 18,029 | SH | DFND | 3 | 18,029 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 6,466 | 320,595 | SH | SOLE | 0 | 320,595 | 0 | 0 | |
| EverQuote Inc | COM CL A | 30041R108 | 6,547 | 190,608 | SH | DFND | 1 | 190,608 | 0 | 0 | |
| EverQuote Inc | COM CL A | 30041R108 | 7,338 | 213,616 | SH | DFND | 2 | 74,968 | 0 | 138,648 | |
| EverQuote Inc | COM CL A | 30041R108 | 2,512 | 73,143 | SH | DFND | 3 | 73,143 | 0 | 0 | |
| EverQuote Inc | COM CL A | 30041R108 | 5,146 | 149,814 | SH | SOLE | 0 | 149,814 | 0 | 0 | |
| Eversource Energy | COM | 30040W108 | 889 | 10,450 | SH | DFND | 1 | 10,450 | 0 | 0 | |
| Exact Sciences | COM | 30063P105 | 21,518 | 232,681 | SH | DFND | 1 | 232,681 | 0 | 0 | |
| Exact Sciences | COM | 30063P105 | 20,498 | 221,653 | SH | DFND | 2 | 82,465 | 0 | 139,188 | |
| Exact Sciences | COM | 30063P105 | 8,810 | 95,269 | SH | DFND | 3 | 87,672 | 0 | 7,597 | |
| Exact Sciences | COM | 30063P105 | 15,804 | 170,891 | SH | SOLE | 0 | 170,891 | 0 | 0 | |
| Exelon Corporation | COM | 30161N101 | 709 | 15,550 | SH | DFND | 1 | 15,550 | 0 | 0 | |
| Facebook Cl.A | CL A | 30303M102 | 1,777,830 | 8,661,779 | SH | DFND | 2 | 4,399,708 | 0 | 4,262,071 | |
| Facebook Cl.A | CL A | 30303M102 | 406,710 | 1,981,535 | SH | DFND | 1 | 1,981,535 | 0 | 0 | |
| Facebook Cl.A | CL A | 30303M102 | 159,489 | 777,046 | SH | DFND | 3 | 494,921 | 0 | 282,125 | |
| Facebook Cl.A | CL A | 30303M102 | 819,820 | 3,994,253 | SH | SOLE | 0 | 2,937,844 | 0 | 1,056,409 | |
| Farfetch | ORD SHS CL A | 30744W107 | 1,904 | 183,980 | SH | DFND | 1 | 183,980 | 0 | 0 | |
| Farfetch | ORD SHS CL A | 30744W107 | 1,129 | 109,046 | SH | DFND | 3 | 109,046 | 0 | 0 | |
| Farfetch | ORD SHS CL A | 30744W107 | 18,151 | 1,753,695 | SH | SOLE | 0 | 1,401,206 | 0 | 352,489 | |
| Faro Technologies | COM | 311642102 | 5,121 | 101,715 | SH | DFND | 1 | 101,715 | 0 | 0 | |
| Faro Technologies | COM | 311642102 | 7,851 | 155,921 | SH | DFND | 2 | 55,490 | 0 | 100,431 | |
| Faro Technologies | COM | 311642102 | 2,751 | 54,646 | SH | DFND | 3 | 54,646 | 0 | 0 | |
| Faro Technologies | COM | 311642102 | 5,432 | 107,880 | SH | SOLE | 0 | 107,880 | 0 | 0 | |
| Fastenal | COM | 311900104 | 17,686 | 478,660 | SH | DFND | 2 | 435,892 | 0 | 42,768 | |
| Fastenal | COM | 311900104 | 28,462 | 770,293 | SH | DFND | 1 | 770,293 | 0 | 0 | |
| Fastenal | COM | 311900104 | 2,974 | 80,495 | SH | DFND | 3 | 49,584 | 0 | 30,911 | |
| Fastenal | COM | 311900104 | 30,153 | 816,054 | SH | SOLE | 0 | 816,054 | 0 | 0 | |
| Ferrari NV | COM | N3167Y103 | 1,917,245 | 11,548,433 | SH | DFND | 2 | 8,734,239 | 0 | 2,814,194 | |
| Ferrari NV | COM | N3167Y103 | 332,534 | 2,003,000 | SH | SOLE | 0 | 2,003,000 | 0 | 0 | |
| Fiat Chrysler Automobiles | SHS | N31738102 | 516,207 | 34,854,707 | SH | DFND | 2 | 25,329,577 | 0 | 9,525,130 | |
| First Republic Bank | COM | 33616C100 | 156,401 | 1,331,637 | SH | DFND | 1 | 1,331,637 | 0 | 0 | |
| First Republic Bank | COM | 33616C100 | 8,085 | 68,841 | SH | DFND | 3 | 48,728 | 0 | 20,113 | |
| First Republic Bank | COM | 33616C100 | 52,257 | 444,931 | SH | SOLE | 0 | 444,931 | 0 | 0 | |
| First Republic Bank | COM | 33616C100 | 190,880 | 1,625,198 | SH | DFND | 2 | 1,625,198 | 0 | 0 | |
| Foamix Pharmaceuticals | SHS | M46135105 | 370 | 111,200 | SH | SOLE | 0 | 111,200 | 0 | 0 | |
| Foamix Pharmaceuticals | SHS | M46135105 | 360 | 108,200 | SH | DFND | 1 | 108,200 | 0 | 0 | |
| Fortive Corp | COM | 34959J108 | 19,346 | 253,249 | SH | SOLE | 0 | 253,249 | 0 | 0 | |
| Fortive Corp | COM | 34959J108 | 2,951 | 38,633 | SH | DFND | 3 | 27,485 | 0 | 11,148 | |
| Fortive Corp | COM | 34959J108 | 68,503 | 896,748 | SH | DFND | 2 | 896,748 | 0 | 0 | |
| Fortive Corp | COM | 34959J108 | 57,991 | 759,150 | SH | DFND | 1 | 759,150 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 81,997 | 1,505,354 | SH | DFND | 1 | 1,505,354 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 84,506 | 1,551,420 | SH | DFND | 2 | 1,512,837 | 0 | 38,583 | |
| Glaukos Corp | COM | 377322102 | 2,950 | 54,153 | SH | DFND | 3 | 44,204 | 0 | 9,949 | |
| Glaukos Corp | COM | 377322102 | 25,391 | 466,142 | SH | SOLE | 0 | 466,142 | 0 | 0 | |
| Grubhub Inc | COM | 400110102 | 134,064 | 2,756,258 | SH | DFND | 1 | 2,756,258 | 0 | 0 | |
| Grubhub Inc | COM | 400110102 | 210,226 | 4,322,078 | SH | DFND | 2 | 3,875,121 | 0 | 446,957 | |
| Grubhub Inc | COM | 400110102 | 103,454 | 2,126,934 | SH | SOLE | 0 | 2,026,222 | 0 | 100,712 | |
| Grubhub Inc | COM | 400110102 | 27,342 | 562,123 | SH | DFND | 3 | 423,291 | 0 | 138,832 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 6,550 | 403,569 | SH | DFND | 2 | 71,617 | 0 | 331,952 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 1,914 | 117,932 | SH | DFND | 1 | 117,932 | 0 | 0 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 8,157 | 502,610 | SH | DFND | 3 | 19,686 | 0 | 482,924 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 50,551 | 797,708 | SH | DFND | 2 | 603,578 | 0 | 194,130 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 9,264 | 146,183 | SH | DFND | 3 | 79,023 | 0 | 67,160 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 90,853 | 1,433,688 | SH | SOLE | 0 | 1,317,134 | 0 | 116,554 | |
| HEICO | COM | 422806109 | 17,460 | 152,960 | SH | DFND | 1 | 152,960 | 0 | 0 | |
| HEICO | COM | 422806109 | 8,364 | 73,276 | SH | SOLE | 0 | 73,276 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 36,237 | 404,749 | SH | DFND | 1 | 404,749 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 66,185 | 739,245 | SH | DFND | 2 | 739,245 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 668 | 7,463 | SH | DFND | 3 | 7,463 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 7,854 | 87,727 | SH | SOLE | 0 | 87,727 | 0 | 0 | |
| Health Catalyst Inc | COM | 42225T107 | 86 | 2,492 | SH | DFND | 3 | 2,492 | 0 | 0 | |
| Howard Hughes | COM | 44267D107 | 26,347 | 207,781 | SH | DFND | 1 | 207,781 | 0 | 0 | |
| Howard Hughes | COM | 44267D107 | 93,801 | 739,758 | SH | DFND | 2 | 662,077 | 0 | 77,681 | |
| Howard Hughes | COM | 44267D107 | 18,036 | 142,240 | SH | DFND | 3 | 93,267 | 0 | 48,973 | |
| Howard Hughes | COM | 44267D107 | 65,845 | 519,279 | SH | SOLE | 0 | 482,515 | 0 | 36,764 | |
| Hutchison China Meditech | SPONSORED ADR | 44842L103 | 4,792 | 191,146 | SH | DFND | 3 | 0 | 0 | 191,146 | |
| Hutchison China Meditech | SPONSORED ADR | 44842L103 | 671 | 26,765 | SH | DFND | 1 | 26,765 | 0 | 0 | |
| ICICI Bank ADR | ADR | 45104G104 | 68,385 | 4,531,807 | SH | DFND | 3 | 3,061,232 | 0 | 1,470,575 | |
| ICICI Bank ADR | ADR | 45104G104 | 158,324 | 10,492,003 | SH | DFND | 2 | 8,826,890 | 0 | 1,665,113 | |
| ICICI Bank ADR | ADR | 45104G104 | 149,130 | 9,882,734 | SH | DFND | 1 | 9,882,734 | 0 | 0 | |
| ICICI Bank ADR | ADR | 45104G104 | 221,159 | 14,655,976 | SH | SOLE | 0 | 13,799,576 | 0 | 856,400 | |
| IPG Photonics Corp | COM | 44980X109 | 4,999 | 34,492 | SH | DFND | 3 | 34,492 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 14,786 | 102,032 | SH | DFND | 2 | 35,921 | 0 | 66,111 | |
| IPG Photonics Corp | COM | 44980X109 | 11,586 | 79,947 | SH | DFND | 1 | 79,947 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 10,671 | 73,636 | SH | SOLE | 0 | 73,636 | 0 | 0 | |
| Illumina | COM | 452327109 | 542,895 | 1,636,506 | SH | DFND | 1 | 1,636,506 | 0 | 0 | |
| Illumina | COM | 452327109 | 3,525,762 | 10,628,088 | SH | DFND | 2 | 6,579,049 | 0 | 4,049,039 | |
| Illumina | COM | 452327109 | 174,237 | 525,222 | SH | DFND | 3 | 330,946 | 0 | 194,276 | |
| Illumina | COM | 452327109 | 1,642,077 | 4,949,891 | SH | SOLE | 0 | 4,041,196 | 0 | 908,695 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 8,951 | 867,316 | SH | DFND | 1 | 867,316 | 0 | 0 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 4,732 | 458,486 | SH | DFND | 2 | 371,200 | 0 | 87,286 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 2,848 | 276,005 | SH | DFND | 3 | 153,588 | 0 | 122,417 | |
| Interactive Brokers Group | COM | 45841N107 | 81,797 | 1,754,556 | SH | DFND | 1 | 1,754,556 | 0 | 0 | |
| Interactive Brokers Group | COM | 45841N107 | 155,327 | 3,331,762 | SH | DFND | 2 | 3,125,091 | 0 | 206,671 | |
| Interactive Brokers Group | COM | 45841N107 | 79,230 | 1,699,485 | SH | SOLE | 0 | 1,604,026 | 0 | 95,459 | |
| Interactive Brokers Group | COM | 45841N107 | 21,157 | 453,827 | SH | DFND | 3 | 304,611 | 0 | 149,216 | |
| Intuitive Surgical | COM NEW | 46120E602 | 109,779 | 185,704 | SH | DFND | 1 | 185,704 | 0 | 0 | |
| Intuitive Surgical | COM NEW | 46120E602 | 740,727 | 1,253,027 | SH | DFND | 2 | 438,653 | 0 | 814,374 | |
| Intuitive Surgical | COM NEW | 46120E602 | 52,952 | 89,575 | SH | DFND | 3 | 55,433 | 0 | 34,142 | |
| Intuitive Surgical | COM NEW | 46120E602 | 383,643 | 648,978 | SH | SOLE | 0 | 454,172 | 0 | 194,806 | |
| Invesco Senior Income Trust | COM | 46131H107 | 9,438 | 2,200,091 | SH | DFND | 1 | 2,200,091 | 0 | 0 | |
| Invesco Senior Income Trust | COM | 46131H107 | 996 | 232,277 | SH | DFND | 3 | 232,277 | 0 | 0 | |
| Ionis Pharmaceuticals | COM | 462222100 | 51,303 | 849,248 | SH | DFND | 1 | 849,248 | 0 | 0 | |
| Ionis Pharmaceuticals | COM | 462222100 | 110,957 | 1,836,725 | SH | SOLE | 0 | 947,713 | 0 | 889,012 | |
| Ionis Pharmaceuticals | COM | 462222100 | 24,437 | 404,521 | SH | DFND | 3 | 248,515 | 0 | 156,006 | |
| Ionis Pharmaceuticals | COM | 462222100 | 344,309 | 5,699,531 | SH | DFND | 2 | 2,000,565 | 0 | 3,698,966 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 233,322 | 25,499,650 | SH | DFND | 2 | 12,659,071 | 0 | 12,840,579 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 110,585 | 12,085,780 | SH | DFND | 3 | 404,978 | 0 | 11,680,802 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 20,413 | 2,230,937 | SH | DFND | 1 | 2,230,937 | 0 | 0 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 19,201 | 2,098,498 | SH | SOLE | 0 | 2,098,498 | 0 | 0 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 51,235 | 1,454,309 | SH | DFND | 1 | 1,454,309 | 0 | 0 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 50,120 | 1,422,638 | SH | DFND | 2 | 269,213 | 0 | 1,153,425 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 61,697 | 1,751,256 | SH | DFND | 3 | 126,933 | 0 | 1,624,323 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 13,137 | 372,889 | SH | SOLE | 0 | 372,889 | 0 | 0 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 37,023 | 1,732,474 | SH | DFND | 1 | 1,732,474 | 0 | 0 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 127,610 | 5,971,433 | SH | DFND | 2 | 5,324,434 | 0 | 646,999 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 88,555 | 4,143,883 | SH | SOLE | 0 | 3,845,645 | 0 | 298,238 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 24,666 | 1,154,235 | SH | DFND | 3 | 763,375 | 0 | 390,860 | |
| Jianpu Technology Inc- ADR | ADR | 47738D101 | 1,442 | 967,818 | SH | SOLE | 0 | 967,818 | 0 | 0 | |
| Jianpu Technology Inc- ADR | ADR | 47738D101 | 1,665 | 1,117,238 | SH | DFND | 1 | 1,117,238 | 0 | 0 | |
| Jumia Technologies Ag ADR | SPONSORED ADS | 48138M105 | 62,199 | 9,242,106 | SH | DFND | 2 | 8,993,950 | 0 | 248,156 | |
| Kaleido Biosciences Inc | COM | 483347100 | 1,237 | 246,500 | SH | DFND | 1 | 246,500 | 0 | 0 | |
| Kaleido Biosciences Inc | COM | 483347100 | 971 | 193,500 | SH | SOLE | 0 | 193,500 | 0 | 0 | |
| Kirby | COM | 497266106 | 86,027 | 960,871 | SH | DFND | 1 | 960,871 | 0 | 0 | |
| Kirby | COM | 497266106 | 303,639 | 3,391,480 | SH | DFND | 2 | 3,039,222 | 0 | 352,258 | |
| Kirby | COM | 497266106 | 205,086 | 2,290,696 | SH | SOLE | 0 | 2,120,045 | 0 | 170,651 | |
| Kirby | COM | 497266106 | 58,725 | 655,930 | SH | DFND | 3 | 438,531 | 0 | 217,399 | |
| Korea Electric Power ADR | SPONSORED ADR | 500631106 | 20 | 1,700 | SH | DFND | 2 | 1,700 | 0 | 0 | |
| Korea Electric Power ADR | SPONSORED ADR | 500631106 | 1,131 | 95,600 | SH | DFND | 3 | 95,600 | 0 | 0 | |
| LIBERTY MEDIA CORP | DEB 4.00011/1 | 530715AG6 | 21,204 | 32,556,000 | SH | DFND | 1 | 32,556,000 | 0 | 0 | |
| LIBERTY MEDIA CORP | DEB 4.00011/1 | 530715AG6 | 6 | 9,000 | SH | DFND | 2 | 9,000 | 0 | 0 | |
| LIBERTY MEDIA CORP | DEB 4.00011/1 | 530715AG6 | 1,112 | 1,708,000 | SH | DFND | 3 | 1,708,000 | 0 | 0 | |
| LendingTree | COM | 52603B107 | 79,288 | 261,298 | SH | DFND | 1 | 261,298 | 0 | 0 | |
| LendingTree | COM | 52603B107 | 174,506 | 575,091 | SH | DFND | 2 | 410,679 | 0 | 164,412 | |
| LendingTree | COM | 52603B107 | 46,377 | 152,836 | SH | DFND | 3 | 122,653 | 0 | 30,183 | |
| LendingTree | COM | 52603B107 | 109,792 | 361,826 | SH | SOLE | 0 | 343,510 | 0 | 18,316 | |
| Lindblad Expeditions Holdings | COM | 535219109 | 11,445 | 700,000 | SH | SOLE | 0 | 700,000 | 0 | 0 | |
| Line Corp Sponsored Adr | SPONSORED ADR | 53567X101 | 15,490 | 316,052 | SH | DFND | 2 | 12,867 | 0 | 303,185 | |
| Liveramp Holdings Inc | COM | 53815P108 | 11,359 | 236,300 | SH | DFND | 1 | 236,300 | 0 | 0 | |
| Liveramp Holdings Inc | COM | 53815P108 | 13,652 | 284,000 | SH | DFND | 2 | 99,700 | 0 | 184,300 | |
| Liveramp Holdings Inc | COM | 53815P108 | 4,677 | 97,300 | SH | DFND | 3 | 97,300 | 0 | 0 | |
| Liveramp Holdings Inc | COM | 53815P108 | 8,922 | 185,600 | SH | SOLE | 0 | 185,600 | 0 | 0 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 29,127 | 677,052 | SH | DFND | 1 | 677,052 | 0 | 0 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 47,754 | 1,110,044 | SH | DFND | 2 | 921,575 | 0 | 188,469 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 1,838 | 42,721 | SH | DFND | 3 | 29,421 | 0 | 13,300 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 79,800 | 1,854,945 | SH | SOLE | 0 | 1,854,945 | 0 | 0 | |
| M&T Bank | COM | 55261F104 | 14,850 | 87,482 | SH | DFND | 2 | 87,482 | 0 | 0 | |
| MRC Global | COM | 55345K103 | 8,866 | 650,000 | SH | SOLE | 0 | 650,000 | 0 | 0 | |
| MakeMyTrip | SHS | V5633W109 | 75,725 | 3,306,787 | SH | DFND | 2 | 2,214,013 | 0 | 1,092,774 | |
| Markel Corp | COM | 570535104 | 293,088 | 256,382 | SH | DFND | 2 | 235,260 | 0 | 21,122 | |
| Markel Corp | COM | 570535104 | 109,093 | 95,430 | SH | DFND | 1 | 95,430 | 0 | 0 | |
| Markel Corp | COM | 570535104 | 46,981 | 41,097 | SH | DFND | 3 | 27,365 | 0 | 13,732 | |
| Markel Corp | COM | 570535104 | 171,123 | 149,692 | SH | SOLE | 0 | 139,848 | 0 | 9,844 | |
| MarketAxess Holdings | COM | 57060D108 | 349,230 | 921,184 | SH | DFND | 1 | 921,184 | 0 | 0 | |
| MarketAxess Holdings | COM | 57060D108 | 505,049 | 1,332,196 | SH | DFND | 2 | 1,183,460 | 0 | 148,736 | |
| MarketAxess Holdings | COM | 57060D108 | 64,480 | 170,082 | SH | DFND | 3 | 133,124 | 0 | 36,958 | |
| MarketAxess Holdings | COM | 57060D108 | 226,762 | 598,144 | SH | SOLE | 0 | 577,712 | 0 | 20,432 | |
| Martin Marietta Materials | COM | 573284106 | 98,757 | 353,157 | SH | DFND | 1 | 353,157 | 0 | 0 | |
| Martin Marietta Materials | COM | 573284106 | 236,810 | 846,840 | SH | SOLE | 0 | 785,462 | 0 | 61,378 | |
| Martin Marietta Materials | COM | 573284106 | 66,877 | 239,155 | SH | DFND | 3 | 160,101 | 0 | 79,054 | |
| Martin Marietta Materials | COM | 573284106 | 359,951 | 1,287,196 | SH | DFND | 2 | 1,154,146 | 0 | 133,050 | |
| Masimo Corp | COM | 574795100 | 69 | 438 | SH | DFND | 3 | 438 | 0 | 0 | |
| Mastercard Inc-Class A | CL A | 57636Q104 | 837,741 | 2,805,658 | SH | DFND | 2 | 2,594,765 | 0 | 210,893 | |
| Mastercard Inc-Class A | CL A | 57636Q104 | 119,612 | 400,589 | SH | DFND | 3 | 269,814 | 0 | 130,775 | |
| Mastercard Inc-Class A | CL A | 57636Q104 | 359,894 | 1,205,312 | SH | DFND | 1 | 1,205,312 | 0 | 0 | |
| Mastercard Inc-Class A | CL A | 57636Q104 | 454,586 | 1,522,442 | SH | SOLE | 0 | 1,425,228 | 0 | 97,214 | |
| McDonald's | COM | 580135101 | 18 | 90 | SH | DFND | 3 | 90 | 0 | 0 | |
| McDonald's | COM | 580135101 | 1,003 | 5,074 | SH | DFND | 2 | 0 | 0 | 5,074 | |
| McDonald's | COM | 580135101 | 14,431 | 73,028 | SH | DFND | 1 | 73,028 | 0 | 0 | |
| McDonald's | COM | 580135101 | 17,501 | 88,564 | SH | SOLE | 0 | 88,564 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 95,773 | 167,453 | SH | DFND | 1 | 167,453 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 96,903 | 169,428 | SH | SOLE | 0 | 169,428 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 11,857 | 20,731 | SH | DFND | 3 | 20,731 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 2,313,059 | 4,044,233 | SH | DFND | 2 | 3,226,133 | 0 | 818,100 | |
| Mettler-Toledo | COM | 592688105 | 78,137 | 98,499 | SH | DFND | 1 | 98,499 | 0 | 0 | |
| Mettler-Toledo | COM | 592688105 | 391,638 | 493,695 | SH | DFND | 2 | 344,246 | 0 | 149,449 | |
| Mettler-Toledo | COM | 592688105 | 1,799 | 2,268 | SH | DFND | 3 | 2,268 | 0 | 0 | |
| Mettler-Toledo | COM | 592688105 | 46,061 | 58,064 | SH | SOLE | 0 | 58,064 | 0 | 0 | |
| Microsoft | COM | 594918104 | 158,892 | 1,007,556 | SH | DFND | 1 | 1,007,556 | 0 | 0 | |
| Microsoft | COM | 594918104 | 537,835 | 3,410,494 | SH | DFND | 2 | 3,079,209 | 0 | 331,285 | |
| Microsoft | COM | 594918104 | 91,901 | 582,758 | SH | DFND | 3 | 388,025 | 0 | 194,733 | |
| Microsoft | COM | 594918104 | 348,552 | 2,210,223 | SH | SOLE | 0 | 2,059,912 | 0 | 150,311 | |
| Mobile Telesystems ADR | SPONSORED ADR | 607409109 | 214 | 21,100 | SH | DFND | 1 | 21,100 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 28,792 | 1,471,961 | SH | DFND | 1 | 1,471,961 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 29,327 | 1,499,317 | SH | DFND | 2 | 1,427,340 | 0 | 71,977 | |
| Moderna Inc | COM | 60770K107 | 7,979 | 407,911 | SH | SOLE | 0 | 407,911 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 722 | 36,924 | SH | DFND | 3 | 36,924 | 0 | 0 | |
| Moody's Corp | COM | 615369105 | 174,911 | 736,746 | SH | DFND | 1 | 736,746 | 0 | 0 | |
| Moody's Corp | COM | 615369105 | 636,047 | 2,679,108 | SH | DFND | 2 | 2,402,102 | 0 | 277,006 | |
| Moody's Corp | COM | 615369105 | 118,732 | 500,115 | SH | DFND | 3 | 333,721 | 0 | 166,394 | |
| Moody's Corp | COM | 615369105 | 410,498 | 1,729,068 | SH | SOLE | 0 | 1,599,373 | 0 | 129,695 | |
| Myriad Genetics Inc | COM | 62855J104 | 22,277 | 818,112 | SH | DFND | 3 | 543,265 | 0 | 274,847 | |
| Myriad Genetics Inc | COM | 62855J104 | 32,811 | 1,204,954 | SH | DFND | 1 | 1,204,954 | 0 | 0 | |
| Myriad Genetics Inc | COM | 62855J104 | 112,957 | 4,148,257 | SH | DFND | 2 | 3,698,268 | 0 | 449,989 | |
| Myriad Genetics Inc | COM | 62855J104 | 76,077 | 2,793,855 | SH | SOLE | 0 | 2,584,694 | 0 | 209,161 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 9,034 | 2,247,309 | SH | DFND | 3 | 1,389,226 | 0 | 858,083 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 250,905 | 62,414,227 | SH | DFND | 2 | 38,010,827 | 0 | 24,403,400 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 18,177 | 4,521,662 | SH | DFND | 1 | 4,521,662 | 0 | 0 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 129,393 | 32,187,233 | SH | SOLE | 0 | 27,472,924 | 0 | 4,714,309 | |
| NVIDIA | COM | 67066G104 | 69,580 | 295,706 | SH | DFND | 3 | 184,109 | 0 | 111,597 | |
| NVIDIA | COM | 67066G104 | 1,029,939 | 4,377,131 | SH | DFND | 2 | 1,765,161 | 0 | 2,611,970 | |
| NVIDIA | COM | 67066G104 | 194,551 | 826,822 | SH | DFND | 1 | 826,822 | 0 | 0 | |
| NVIDIA | COM | 67066G104 | 520,410 | 2,211,688 | SH | SOLE | 0 | 1,602,376 | 0 | 609,312 | |
| National Instruments Corp | COM | 636518102 | 13,411 | 316,757 | SH | DFND | 1 | 316,757 | 0 | 0 | |
| National Instruments Corp | COM | 636518102 | 6,678 | 157,734 | SH | DFND | 2 | 50,678 | 0 | 107,056 | |
| National Instruments Corp | COM | 636518102 | 2,128 | 50,271 | SH | DFND | 3 | 50,271 | 0 | 0 | |
| National Instruments Corp | COM | 636518102 | 15,436 | 364,562 | SH | SOLE | 0 | 364,562 | 0 | 0 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 68,447 | 223,216 | SH | DFND | 1 | 223,216 | 0 | 0 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 425,718 | 1,388,332 | SH | DFND | 2 | 477,217 | 0 | 911,115 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 30,580 | 99,725 | SH | DFND | 3 | 61,004 | 0 | 38,721 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 139,644 | 455,399 | SH | SOLE | 0 | 236,673 | 0 | 218,726 | |
| Netflix Inc | COM | 64110L106 | 403,007 | 1,245,501 | SH | DFND | 1 | 1,245,501 | 0 | 0 | |
| Netflix Inc | COM | 64110L106 | 1,331,398 | 4,114,714 | SH | DFND | 2 | 2,186,868 | 0 | 1,927,846 | |
| Netflix Inc | COM | 64110L106 | 766,448 | 2,368,725 | SH | SOLE | 0 | 1,900,020 | 0 | 468,705 | |
| Netflix Inc | COM | 64110L106 | 101,923 | 314,995 | SH | DFND | 3 | 201,594 | 0 | 113,401 | |
| New Relic | COM | 64829B100 | 481 | 7,325 | SH | DFND | 3 | 7,325 | 0 | 0 | |
| New Relic | COM | 64829B100 | 37,588 | 572,024 | SH | DFND | 2 | 572,024 | 0 | 0 | |
| New Relic | COM | 64829B100 | 36,238 | 551,482 | SH | DFND | 1 | 551,482 | 0 | 0 | |
| New Relic | COM | 64829B100 | 11,753 | 178,864 | SH | SOLE | 0 | 178,864 | 0 | 0 | |
| Novocure Ltd | ORD SHS | G6674U108 | 37,116 | 440,443 | SH | DFND | 3 | 344,822 | 0 | 95,621 | |
| Novocure Ltd | ORD SHS | G6674U108 | 291,246 | 3,456,110 | SH | DFND | 2 | 3,063,290 | 0 | 392,820 | |
| Novocure Ltd | ORD SHS | G6674U108 | 196,890 | 2,336,416 | SH | DFND | 1 | 2,336,416 | 0 | 0 | |
| Novocure Ltd | ORD SHS | G6674U108 | 149,665 | 1,776,013 | SH | SOLE | 0 | 1,699,382 | 0 | 76,631 | |
| Now Inc/DE | COM | 67011P100 | 14,327 | 1,274,625 | SH | DFND | 1 | 1,274,625 | 0 | 0 | |
| Now Inc/DE | COM | 67011P100 | 54,431 | 4,842,576 | SH | DFND | 2 | 4,378,270 | 0 | 464,306 | |
| Now Inc/DE | COM | 67011P100 | 9,350 | 831,833 | SH | DFND | 3 | 566,649 | 0 | 265,184 | |
| Now Inc/DE | COM | 67011P100 | 40,128 | 3,570,136 | SH | SOLE | 0 | 3,351,808 | 0 | 218,328 | |
| Nucana Plc ADR | SPONSORED ADR | 67022C106 | 2,050 | 336,100 | SH | SOLE | 0 | 336,100 | 0 | 0 | |
| Nucana Plc ADR | SPONSORED ADR | 67022C106 | 2,996 | 491,208 | SH | DFND | 1 | 491,208 | 0 | 0 | |
| Nuveen Senior Income Fund | COM | 67067Y104 | 2,245 | 376,702 | SH | DFND | 1 | 376,702 | 0 | 0 | |
| Orchard Therapeutics PLC ADR | ADS | 68570P101 | 37,675 | 2,740,000 | SH | SOLE | 0 | 2,740,000 | 0 | 0 | |
| Pacira BioSciences | COM | 695127100 | 18,218 | 402,169 | SH | DFND | 2 | 154,874 | 0 | 247,295 | |
| Pacira BioSciences | COM | 695127100 | 21,904 | 483,526 | SH | DFND | 1 | 483,526 | 0 | 0 | |
| Pacira BioSciences | COM | 695127100 | 8,684 | 191,691 | SH | DFND | 3 | 169,100 | 0 | 22,591 | |
| Pacira BioSciences | COM | 695127100 | 14,046 | 310,059 | SH | SOLE | 0 | 310,059 | 0 | 0 | |
| Peloton Interactive Inc | CL A COM | 70614W100 | 38,462 | 1,354,290 | SH | DFND | 1 | 1,354,290 | 0 | 0 | |
| Peloton Interactive Inc | CL A COM | 70614W100 | 251,254 | 8,846,964 | SH | DFND | 2 | 3,074,669 | 0 | 5,772,295 | |
| Peloton Interactive Inc | CL A COM | 70614W100 | 81,902 | 2,883,865 | SH | SOLE | 0 | 1,444,921 | 0 | 1,438,944 | |
| Peloton Interactive Inc | CL A COM | 70614W100 | 18,623 | 655,727 | SH | DFND | 3 | 407,100 | 0 | 248,627 | |
| Penumbra Inc | COM | 70975L107 | 68,068 | 414,367 | SH | DFND | 1 | 414,367 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 1,130 | 6,878 | SH | DFND | 3 | 6,878 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 68,826 | 418,983 | SH | DFND | 2 | 418,983 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 21,831 | 132,898 | SH | SOLE | 0 | 132,898 | 0 | 0 | |
| Pepsico | COM | 713448108 | 1,475 | 10,794 | SH | DFND | 2 | 0 | 0 | 10,794 | |
| Pepsico | COM | 713448108 | 22,285 | 163,059 | SH | DFND | 1 | 163,059 | 0 | 0 | |
| Pepsico | COM | 713448108 | 28 | 206 | SH | DFND | 3 | 206 | 0 | 0 | |
| Pepsico | COM | 713448108 | 26,689 | 195,281 | SH | SOLE | 0 | 195,281 | 0 | 0 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 70,238 | 4,406,379 | SH | DFND | 1 | 4,406,379 | 0 | 0 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 356,700 | 22,377,664 | SH | DFND | 2 | 7,584,710 | 0 | 14,792,954 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 11,884 | 745,563 | SH | SOLE | 0 | 745,563 | 0 | 0 | |
| Petrobras Pref ADR | SP ADR NON VTG | 71654V101 | 9,043 | 606,122 | SH | DFND | 1 | 606,122 | 0 | 0 | |
| Petrobras Pref ADR | SP ADR NON VTG | 71654V101 | 61,734 | 4,137,651 | SH | DFND | 2 | 1,818,029 | 0 | 2,319,622 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 54,268 | 1,434,906 | SH | DFND | 1 | 1,434,906 | 0 | 0 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 362,384 | 9,581,814 | SH | DFND | 2 | 3,337,198 | 0 | 6,244,616 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 198,351 | 5,244,596 | SH | SOLE | 0 | 3,727,801 | 0 | 1,516,795 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 26,199 | 692,732 | SH | DFND | 3 | 425,041 | 0 | 267,691 | |
| Pioneer Floating Rate Trust | COM | 72369J102 | 5,935 | 541,036 | SH | DFND | 1 | 541,036 | 0 | 0 | |
| Procter & Gamble | COM | 742718109 | 26,974 | 215,967 | SH | DFND | 1 | 215,967 | 0 | 0 | |
| Procter & Gamble | COM | 742718109 | 34 | 271 | SH | DFND | 3 | 271 | 0 | 0 | |
| Procter & Gamble | COM | 742718109 | 1,809 | 14,481 | SH | DFND | 2 | 0 | 0 | 14,481 | |
| Procter & Gamble | COM | 742718109 | 31,879 | 255,233 | SH | SOLE | 0 | 255,233 | 0 | 0 | |
| Redfin | COM | 75737F108 | 3,480 | 164,606 | SH | DFND | 3 | 117,917 | 0 | 46,689 | |
| Redfin | COM | 75737F108 | 71,585 | 3,386,241 | SH | DFND | 2 | 3,386,241 | 0 | 0 | |
| Redfin | COM | 75737F108 | 70,509 | 3,335,323 | SH | DFND | 1 | 3,335,323 | 0 | 0 | |
| Redfin | COM | 75737F108 | 23,584 | 1,115,599 | SH | SOLE | 0 | 1,115,599 | 0 | 0 | |
| ResMed | COM | 761152107 | 93,117 | 600,869 | SH | DFND | 1 | 600,869 | 0 | 0 | |
| ResMed | COM | 761152107 | 220,980 | 1,425,956 | SH | SOLE | 0 | 1,322,329 | 0 | 103,627 | |
| ResMed | COM | 761152107 | 329,036 | 2,123,221 | SH | DFND | 2 | 1,899,944 | 0 | 223,277 | |
| ResMed | COM | 761152107 | 63,335 | 408,690 | SH | DFND | 3 | 273,378 | 0 | 135,312 | |
| ResTORbio Inc | COM | 76133L103 | 975 | 654,147 | SH | DFND | 1 | 654,147 | 0 | 0 | |
| ResTORbio Inc | COM | 76133L103 | 920 | 617,240 | SH | SOLE | 0 | 617,240 | 0 | 0 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 26,026 | 605,968 | SH | DFND | 3 | 402,342 | 0 | 203,626 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 219,148 | 5,102,387 | SH | DFND | 2 | 4,339,825 | 0 | 762,562 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 38,294 | 891,597 | SH | DFND | 1 | 891,597 | 0 | 0 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 89,593 | 2,085,977 | SH | SOLE | 0 | 1,930,247 | 0 | 155,730 | |
| Ritchie Bros. Auctioneers | COM | 767744105 | 54,596 | 1,270,590 | SH | DFND | 2 | 714,626 | 0 | 555,964 | |
| Ritchie Bros. Auctioneers | COM | 767744105 | 18,646 | 433,928 | SH | SOLE | 0 | 433,928 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 132,319 | 988,191 | SH | DFND | 1 | 988,191 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 139,481 | 1,041,683 | SH | DFND | 2 | 1,041,683 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 1,818 | 13,575 | SH | DFND | 3 | 13,575 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 43,334 | 323,629 | SH | SOLE | 0 | 323,629 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 4,283 | 450,800 | SH | DFND | 1 | 450,800 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 34,006 | 3,579,565 | SH | SOLE | 0 | 3,579,565 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 533 | 56,095 | SH | DFND | 3 | 56,095 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 1,568 | 165,010 | SH | DFND | 2 | 57,732 | 0 | 107,278 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 586,433 | 6,693,676 | SH | DFND | 2 | 5,206,288 | 0 | 1,487,388 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 4,696 | 53,605 | SH | DFND | 3 | 6,539 | 0 | 47,066 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 4,400 | 50,222 | SH | SOLE | 0 | 50,222 | 0 | 0 | |
| SEA Ltd ADR | ADR | 81141R100 | 28,888 | 718,249 | SH | DFND | 1 | 718,249 | 0 | 0 | |
| SEA Ltd ADR | ADR | 81141R100 | 27,522 | 684,293 | SH | DFND | 2 | 0 | 0 | 684,293 | |
| SEA Ltd ADR | ADR | 81141R100 | 25,785 | 641,104 | SH | SOLE | 0 | 641,104 | 0 | 0 | |
| SINA Corp | ORD | G81477104 | 5,253 | 131,550 | SH | DFND | 3 | 0 | 0 | 131,550 | |
| SUNPOWER CORP | DBCV 4.000 1/1 | 867652AL3 | 4,489 | 5,343,000 | SH | DFND | 1 | 5,343,000 | 0 | 0 | |
| SUNPOWER CORP | DBCV 4.000 1/1 | 867652AL3 | 686 | 817,000 | SH | DFND | 3 | 817,000 | 0 | 0 | |
| Sage Therapeutics Inc | COM | 78667J108 | 35 | 490 | SH | DFND | 3 | 490 | 0 | 0 | |
| Salesforce.com | COM | 79466L302 | 183,776 | 1,129,958 | SH | SOLE | 0 | 584,455 | 0 | 545,503 | |
| Salesforce.com | COM | 79466L302 | 567,709 | 3,490,587 | SH | DFND | 2 | 1,222,746 | 0 | 2,267,841 | |
| Salesforce.com | COM | 79466L302 | 40,423 | 248,544 | SH | DFND | 3 | 153,257 | 0 | 95,287 | |
| Salesforce.com | COM | 79466L302 | 84,650 | 520,474 | SH | DFND | 1 | 520,474 | 0 | 0 | |
| Schlumberger | COM | 806857108 | 3,999 | 99,477 | SH | DFND | 2 | 99,477 | 0 | 0 | |
| Seattle Genetics | COM | 812578102 | 150,778 | 1,319,606 | SH | SOLE | 0 | 1,229,531 | 0 | 90,075 | |
| Seattle Genetics | COM | 812578102 | 221,416 | 1,937,826 | SH | DFND | 2 | 1,682,321 | 0 | 255,505 | |
| Seattle Genetics | COM | 812578102 | 44,089 | 385,866 | SH | DFND | 3 | 268,306 | 0 | 117,560 | |
| Seattle Genetics | COM | 812578102 | 70,079 | 613,331 | SH | DFND | 1 | 613,331 | 0 | 0 | |
| Service Corp.Intl. | COM | 817565104 | 46,129 | 1,002,151 | SH | DFND | 3 | 667,292 | 0 | 334,859 | |
| Service Corp.Intl. | COM | 817565104 | 67,502 | 1,466,479 | SH | DFND | 1 | 1,466,479 | 0 | 0 | |
| Service Corp.Intl. | COM | 817565104 | 162,024 | 3,519,957 | SH | SOLE | 0 | 3,259,409 | 0 | 260,548 | |
| Service Corp.Intl. | COM | 817565104 | 240,031 | 5,214,664 | SH | DFND | 2 | 4,656,833 | 0 | 557,831 | |
| Severstal GDR Reg S | COM | 818150302 | 156 | 10,286 | SH | DFND | 1 | 10,286 | 0 | 0 | |
| Sherwin-Williams Co | COM | 824348106 | 11,428 | 19,584 | SH | DFND | 2 | 19,584 | 0 | 0 | |
| ShockWave Medical Inc | COM | 82489T104 | 39 | 891 | SH | DFND | 3 | 891 | 0 | 0 | |
| Shopify 'A' | CL A | 82509L107 | 521,548 | 1,311,806 | SH | SOLE | 0 | 1,081,063 | 0 | 230,743 | |
| Shopify 'A' | CL A | 82509L107 | 93,044 | 234,027 | SH | DFND | 3 | 153,630 | 0 | 80,397 | |
| Shopify 'A' | CL A | 82509L107 | 1,343,200 | 3,378,439 | SH | DFND | 2 | 2,391,298 | 0 | 987,141 | |
| Shopify 'A' | CL A | 82509L107 | 442,917 | 1,114,032 | SH | DFND | 1 | 1,114,032 | 0 | 0 | |
| SiteOne Landscape Supply | COM | 82982L103 | 30,663 | 338,255 | SH | DFND | 3 | 226,307 | 0 | 111,948 | |
| SiteOne Landscape Supply | COM | 82982L103 | 159,856 | 1,763,438 | SH | DFND | 2 | 1,575,027 | 0 | 188,411 | |
| SiteOne Landscape Supply | COM | 82982L103 | 108,351 | 1,195,264 | SH | SOLE | 0 | 1,107,227 | 0 | 88,037 | |
| SiteOne Landscape Supply | COM | 82982L103 | 47,225 | 520,960 | SH | DFND | 1 | 520,960 | 0 | 0 | |
| Slack Technologies Inc | COM CL A | 83088V102 | 7,672 | 341,276 | SH | DFND | 2 | 0 | 0 | 341,276 | |
| Slack Technologies Inc | COM CL A | 83088V102 | 2,823 | 125,568 | SH | SOLE | 0 | 125,568 | 0 | 0 | |
| Snap Inc | CL A | 83304A106 | 3,024 | 185,160 | SH | DFND | 2 | 185,160 | 0 | 0 | |
| Sohu.com | COM | 83410S108 | 2,238 | 200,140 | SH | DFND | 3 | 0 | 0 | 200,140 | |
| Splunk Inc | COM | 848637104 | 6,899 | 46,066 | SH | DFND | 3 | 46,066 | 0 | 0 | |
| Splunk Inc | COM | 848637104 | 19,843 | 132,487 | SH | DFND | 2 | 46,792 | 0 | 85,695 | |
| Splunk Inc | COM | 848637104 | 11,066 | 73,884 | SH | SOLE | 0 | 73,884 | 0 | 0 | |
| Splunk Inc | COM | 848637104 | 15,118 | 100,940 | SH | DFND | 1 | 100,940 | 0 | 0 | |
| Spotify Technology SA | SHS | L8681T102 | 64,883 | 433,858 | SH | DFND | 3 | 279,231 | 0 | 154,627 | |
| Spotify Technology SA | SHS | L8681T102 | 177,162 | 1,184,633 | SH | DFND | 1 | 1,184,633 | 0 | 0 | |
| Spotify Technology SA | SHS | L8681T102 | 573,682 | 3,836,056 | SH | SOLE | 0 | 3,188,535 | 0 | 647,521 | |
| Spotify Technology SA | SHS | L8681T102 | 2,432,499 | 16,265,454 | SH | DFND | 2 | 11,163,470 | 0 | 5,101,984 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 8,502 | 241,730 | SH | DFND | 3 | 214,122 | 0 | 27,608 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 26,501 | 753,502 | SH | DFND | 1 | 753,502 | 0 | 0 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 14,873 | 422,881 | SH | SOLE | 0 | 422,881 | 0 | 0 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 18,458 | 524,816 | SH | DFND | 2 | 202,242 | 0 | 322,574 | |
| Stericycle Inc | COM | 858912108 | 28,451 | 445,866 | SH | DFND | 3 | 292,866 | 0 | 153,000 | |
| Stericycle Inc | COM | 858912108 | 101,283 | 1,587,262 | SH | SOLE | 0 | 1,468,312 | 0 | 118,950 | |
| Stericycle Inc | COM | 858912108 | 41,330 | 647,697 | SH | DFND | 1 | 647,697 | 0 | 0 | |
| Stericycle Inc | COM | 858912108 | 148,780 | 2,331,606 | SH | DFND | 2 | 2,083,130 | 0 | 248,476 | |
| Stitch Fix | COM CL A | 860897107 | 50,788 | 1,979,282 | SH | DFND | 1 | 1,979,282 | 0 | 0 | |
| Stitch Fix | COM CL A | 860897107 | 52,979 | 2,064,637 | SH | DFND | 2 | 2,064,637 | 0 | 0 | |
| Stitch Fix | COM CL A | 860897107 | 707 | 27,536 | SH | DFND | 3 | 27,536 | 0 | 0 | |
| Stitch Fix | COM CL A | 860897107 | 16,754 | 652,936 | SH | SOLE | 0 | 652,936 | 0 | 0 | |
| StoneCo | COM CL A | G85158106 | 4,396 | 110,200 | SH | DFND | 2 | 110,200 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 2,504 | 123,802 | SH | DFND | 3 | 123,802 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 2,925 | 144,600 | SH | SOLE | 0 | 144,600 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 4,577 | 226,300 | SH | DFND | 1 | 226,300 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 7,287 | 360,307 | SH | DFND | 2 | 126,679 | 0 | 233,628 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 90,728 | 1,882,329 | SH | DFND | 1 | 1,882,329 | 0 | 0 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 1,946,667 | 40,387,276 | SH | DFND | 2 | 29,764,109 | 0 | 10,623,167 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 43,086 | 893,895 | SH | DFND | 3 | 548,817 | 0 | 345,078 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 196,275 | 4,072,105 | SH | SOLE | 0 | 2,123,063 | 0 | 1,949,042 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 46,252 | 930,625 | SH | DFND | 1 | 930,625 | 0 | 0 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 176,290 | 3,547,092 | SH | DFND | 2 | 3,214,031 | 0 | 333,061 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 105,346 | 2,119,635 | SH | SOLE | 0 | 1,965,676 | 0 | 153,959 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 30,221 | 608,064 | SH | DFND | 3 | 406,066 | 0 | 201,998 | |
| TJX Companies | COM | 872540109 | 13,690 | 224,203 | SH | DFND | 1 | 224,203 | 0 | 0 | |
| TJX Companies | COM | 872540109 | 1,864 | 30,526 | SH | DFND | 3 | 18,959 | 0 | 11,567 | |
| TJX Companies | COM | 872540109 | 23,197 | 379,907 | SH | DFND | 2 | 368,597 | 0 | 11,310 | |
| TJX Companies | COM | 872540109 | 4,795 | 78,530 | SH | SOLE | 0 | 78,530 | 0 | 0 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 123,109 | 2,118,921 | SH | DFND | 1 | 2,118,921 | 0 | 0 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 248,819 | 4,282,604 | SH | SOLE | 0 | 3,987,965 | 0 | 294,639 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 68,596 | 1,180,657 | SH | DFND | 3 | 795,923 | 0 | 384,734 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 1,070,557 | 18,426,110 | SH | DFND | 2 | 12,471,741 | 0 | 5,954,369 | |
| Tandem Diabetes Care | COM NEW | 875372203 | 13,418 | 225,100 | SH | DFND | 1 | 225,100 | 0 | 0 | |
| Tandem Diabetes Care | COM NEW | 875372203 | 12,494 | 209,600 | SH | SOLE | 0 | 209,600 | 0 | 0 | |
| Targa Resources | COM | 87612G101 | 106 | 2,599 | SH | DFND | 1 | 2,599 | 0 | 0 | |
| Teladoc | COM | 87918A105 | 113,048 | 1,350,310 | SH | DFND | 1 | 1,350,310 | 0 | 0 | |
| Teladoc | COM | 87918A105 | 211,687 | 2,528,512 | SH | DFND | 2 | 2,129,637 | 0 | 398,875 | |
| Teladoc | COM | 87918A105 | 119,154 | 1,423,250 | SH | SOLE | 0 | 1,343,972 | 0 | 79,278 | |
| Teladoc | COM | 87918A105 | 36,012 | 430,151 | SH | DFND | 3 | 327,253 | 0 | 102,898 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 166,606 | 14,191,328 | SH | DFND | 2 | 9,337,457 | 0 | 4,853,871 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 5,533 | 471,279 | SH | DFND | 1 | 471,279 | 0 | 0 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 17,557 | 1,495,469 | SH | SOLE | 0 | 1,495,469 | 0 | 0 | |
| Teradyne | COM | 880770102 | 60,820 | 891,919 | SH | DFND | 1 | 891,919 | 0 | 0 | |
| Teradyne | COM | 880770102 | 140,818 | 2,065,078 | SH | SOLE | 0 | 1,912,590 | 0 | 152,488 | |
| Teradyne | COM | 880770102 | 41,178 | 603,869 | SH | DFND | 3 | 401,824 | 0 | 202,045 | |
| Teradyne | COM | 880770102 | 315,254 | 4,623,170 | SH | DFND | 2 | 4,287,881 | 0 | 335,289 | |
| TerraForm Power | CL A COM | 88104R209 | 36 | 2,360 | SH | DFND | 2 | 2,360 | 0 | 0 | |
| TerraForm Power | CL A COM | 88104R209 | 34,803 | 2,261,400 | SH | DFND | 1 | 2,261,400 | 0 | 0 | |
| TerraForm Power | CL A COM | 88104R209 | 1,745 | 113,393 | SH | DFND | 3 | 113,393 | 0 | 0 | |
| Tesla Inc | COM | 88160R101 | 3,333,905 | 7,969,558 | SH | DFND | 2 | 5,088,131 | 0 | 2,881,427 | |
| Tesla Inc | COM | 88160R101 | 647,352 | 1,547,468 | SH | DFND | 1 | 1,547,468 | 0 | 0 | |
| Tesla Inc | COM | 88160R101 | 179,867 | 429,965 | SH | DFND | 3 | 284,918 | 0 | 145,047 | |
| Tesla Inc | COM | 88160R101 | 1,623,115 | 3,879,988 | SH | SOLE | 0 | 3,251,048 | 0 | 628,940 | |
| The Trade Desk | COM CL A | 88339J105 | 224,274 | 863,322 | SH | DFND | 1 | 863,322 | 0 | 0 | |
| The Trade Desk | COM CL A | 88339J105 | 317,436 | 1,221,943 | SH | DFND | 2 | 1,166,867 | 0 | 55,076 | |
| The Trade Desk | COM CL A | 88339J105 | 30,928 | 119,055 | SH | DFND | 3 | 81,583 | 0 | 37,472 | |
| The Trade Desk | COM CL A | 88339J105 | 151,401 | 582,805 | SH | SOLE | 0 | 557,107 | 0 | 25,698 | |
| Thermo Fisher Scientific | COM | 883556102 | 95,312 | 293,384 | SH | DFND | 1 | 293,384 | 0 | 0 | |
| Thermo Fisher Scientific | COM | 883556102 | 223,594 | 688,258 | SH | SOLE | 0 | 638,445 | 0 | 49,813 | |
| Thermo Fisher Scientific | COM | 883556102 | 63,694 | 196,061 | SH | DFND | 3 | 130,831 | 0 | 65,230 | |
| Thermo Fisher Scientific | COM | 883556102 | 339,181 | 1,044,053 | SH | DFND | 2 | 936,422 | 0 | 107,631 | |
| Trip.com Group Sponsored ADR | AMERICAN DEP SHS | 89677Q107 | 99,581 | 2,969,027 | SH | DFND | 1 | 2,969,027 | 0 | 0 | |
| Trip.com Group Sponsored ADR | AMERICAN DEP SHS | 89677Q107 | 1,013,367 | 30,213,678 | SH | DFND | 2 | 20,061,224 | 0 | 10,152,454 | |
| Trip.com Group Sponsored ADR | AMERICAN DEP SHS | 89677Q107 | 82,558 | 2,461,473 | SH | DFND | 3 | 992,230 | 0 | 1,469,243 | |
| Trip.com Group Sponsored ADR | AMERICAN DEP SHS | 89677Q107 | 345,704 | 10,307,228 | SH | SOLE | 0 | 8,307,501 | 0 | 1,999,727 | |
| Trupanion | COM | 898202106 | 7,402 | 197,600 | SH | DFND | 1 | 197,600 | 0 | 0 | |
| Trupanion | COM | 898202106 | 12,415 | 331,410 | SH | DFND | 2 | 116,587 | 0 | 214,823 | |
| Trupanion | COM | 898202106 | 4,237 | 113,120 | SH | DFND | 3 | 113,120 | 0 | 0 | |
| Trupanion | COM | 898202106 | 27,533 | 735,000 | SH | SOLE | 0 | 735,000 | 0 | 0 | |
| United Parcel Service | CL B | 911312106 | 17,675 | 150,993 | SH | DFND | 1 | 150,993 | 0 | 0 | |
| United Parcel Service | CL B | 911312106 | 1,180 | 10,080 | SH | DFND | 2 | 0 | 0 | 10,080 | |
| United Parcel Service | CL B | 911312106 | 22 | 190 | SH | DFND | 3 | 190 | 0 | 0 | |
| United Parcel Service | CL B | 911312106 | 21,322 | 182,150 | SH | SOLE | 0 | 182,150 | 0 | 0 | |
| Unity Biotechnology Inc | COM | 91381U101 | 1,788 | 248,000 | SH | DFND | 1 | 248,000 | 0 | 0 | |
| Unity Biotechnology Inc | COM | 91381U101 | 25,632 | 3,555,014 | SH | SOLE | 0 | 3,555,014 | 0 | 0 | |
| Upwork Inc | COM | 91688F104 | 5,059 | 474,100 | SH | DFND | 1 | 474,100 | 0 | 0 | |
| Upwork Inc | COM | 91688F104 | 4,561 | 427,500 | SH | DFND | 2 | 149,300 | 0 | 278,200 | |
| Upwork Inc | COM | 91688F104 | 1,502 | 140,800 | SH | DFND | 3 | 140,800 | 0 | 0 | |
| Upwork Inc | COM | 91688F104 | 3,200 | 299,900 | SH | SOLE | 0 | 299,900 | 0 | 0 | |
| Uxin ADR | ADS | 91818X108 | 2,738 | 1,211,500 | SH | DFND | 1 | 1,211,500 | 0 | 0 | |
| Uxin ADR | ADS | 91818X108 | 1,276 | 564,600 | SH | SOLE | 0 | 564,600 | 0 | 0 | |
| Vale SA ADR | ADR | 91912E105 | 46,467 | 3,520,200 | SH | DFND | 1 | 3,520,200 | 0 | 0 | |
| Vale SA ADR | ADR | 91912E105 | 345,286 | 26,158,000 | SH | DFND | 2 | 10,700,800 | 0 | 15,457,200 | |
| Varian Medical Systems Inc | COM | 92220P105 | 9,518 | 67,021 | SH | DFND | 2 | 67,021 | 0 | 0 | |
| Veeco Instruments | COM | 922417100 | 8,618 | 586,854 | SH | DFND | 1 | 586,854 | 0 | 0 | |
| Veeco Instruments | COM | 922417100 | 7,104 | 483,782 | SH | DFND | 2 | 170,662 | 0 | 313,120 | |
| Veeco Instruments | COM | 922417100 | 2,435 | 165,843 | SH | DFND | 3 | 165,843 | 0 | 0 | |
| Verisk Analytics | COM | 92345Y106 | 10,314 | 69,061 | SH | DFND | 2 | 69,061 | 0 | 0 | |
| Vir Biotechnology Inc | COM | 92764N102 | 6,287 | 500,000 | SH | SOLE | 0 | 500,000 | 0 | 0 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 107,994 | 574,744 | SH | DFND | 1 | 574,744 | 0 | 0 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 380,220 | 2,023,523 | SH | DFND | 2 | 1,810,156 | 0 | 213,367 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 72,670 | 386,748 | SH | DFND | 3 | 257,457 | 0 | 129,291 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 253,151 | 1,347,265 | SH | SOLE | 0 | 1,247,898 | 0 | 99,367 | |
| Voya Prime Rate Trust | SH BEN INT | 92913A100 | 2,861 | 571,000 | SH | DFND | 1 | 571,000 | 0 | 0 | |
| Voya Prime Rate Trust | SH BEN INT | 92913A100 | 969 | 193,400 | SH | DFND | 3 | 193,400 | 0 | 0 | |
| WEC Energy Group | COM | 92939U106 | 896 | 9,720 | SH | DFND | 1 | 9,720 | 0 | 0 | |
| Wabtec | COM | 929740108 | 143,507 | 1,844,560 | SH | DFND | 2 | 1,664,210 | 0 | 180,350 | |
| Wabtec | COM | 929740108 | 25,639 | 329,551 | SH | DFND | 3 | 216,425 | 0 | 113,126 | |
| Wabtec | COM | 929740108 | 37,284 | 479,223 | SH | DFND | 1 | 479,223 | 0 | 0 | |
| Wabtec | COM | 929740108 | 88,934 | 1,143,106 | SH | SOLE | 0 | 1,058,258 | 0 | 84,848 | |
| Waters | COM | 941848103 | 76,062 | 325,539 | SH | DFND | 1 | 325,539 | 0 | 0 | |
| Waters | COM | 941848103 | 263,565 | 1,128,035 | SH | DFND | 2 | 1,016,869 | 0 | 111,166 | |
| Waters | COM | 941848103 | 50,133 | 214,565 | SH | DFND | 3 | 142,112 | 0 | 72,453 | |
| Waters | COM | 941848103 | 163,856 | 701,290 | SH | SOLE | 0 | 647,711 | 0 | 53,579 | |
| Watsco Inc | COM | 942622200 | 120,608 | 669,489 | SH | DFND | 2 | 664,162 | 0 | 5,327 | |
| Watsco Inc | COM | 942622200 | 114,478 | 635,462 | SH | DFND | 1 | 635,462 | 0 | 0 | |
| Watsco Inc | COM | 942622200 | 4,490 | 24,925 | SH | DFND | 3 | 18,071 | 0 | 6,854 | |
| Watsco Inc | COM | 942622200 | 49,108 | 272,595 | SH | SOLE | 0 | 272,595 | 0 | 0 | |
| Wayfair Inc Class A | CL A | 94419L101 | 187,064 | 2,069,978 | SH | DFND | 1 | 2,069,978 | 0 | 0 | |
| Wayfair Inc Class A | CL A | 94419L101 | 196,130 | 2,170,296 | SH | DFND | 2 | 2,001,951 | 0 | 168,345 | |
| Wayfair Inc Class A | CL A | 94419L101 | 13,373 | 147,980 | SH | DFND | 3 | 135,290 | 0 | 12,690 | |
| Wayfair Inc Class A | CL A | 94419L101 | 162,185 | 1,794,674 | SH | SOLE | 0 | 1,794,674 | 0 | 0 | |
| Wheaton Precious Metals | COM | 962879102 | 158 | 5,310 | SH | DFND | 1 | 5,310 | 0 | 0 | |
| Wipro Ltd ADR | SPON ADR 1 SH | 97651M109 | 744 | 198,489 | SH | DFND | 2 | 198,489 | 0 | 0 | |
| Wix Com | SHS | M98068105 | 482,184 | 3,940,059 | SH | DFND | 2 | 2,131,092 | 0 | 1,808,967 | |
| Workday Inc | CL A | 98138H101 | 69,413 | 422,089 | SH | DFND | 1 | 422,089 | 0 | 0 | |
| Workday Inc | CL A | 98138H101 | 464,184 | 2,822,647 | SH | DFND | 2 | 987,329 | 0 | 1,835,318 | |
| Workday Inc | CL A | 98138H101 | 33,139 | 201,517 | SH | DFND | 3 | 124,527 | 0 | 76,990 | |
| Workday Inc | CL A | 98138H101 | 288,939 | 1,757,004 | SH | SOLE | 0 | 1,314,233 | 0 | 442,771 | |
| Xylem | COM | 98419M100 | 8,481 | 107,646 | SH | DFND | 1 | 107,646 | 0 | 0 | |
| Xylem | COM | 98419M100 | 633 | 8,036 | SH | DFND | 3 | 8,036 | 0 | 0 | |
| Xylem | COM | 98419M100 | 9,319 | 118,272 | SH | DFND | 2 | 75,713 | 0 | 42,559 | |
| Yext Inc | COM | 98585N106 | 58,793 | 4,077,187 | SH | DFND | 1 | 4,077,187 | 0 | 0 | |
| Yext Inc | COM | 98585N106 | 25,986 | 1,802,109 | SH | SOLE | 0 | 1,802,109 | 0 | 0 | |
| Yext Inc | COM | 98585N106 | 8,258 | 572,687 | SH | DFND | 3 | 543,912 | 0 | 28,775 | |
| Yext Inc | COM | 98585N106 | 59,620 | 4,134,509 | SH | DFND | 2 | 3,273,760 | 0 | 860,749 | |
| Zai Lab ADR | ADR | 98887Q104 | 33,817 | 813,100 | SH | DFND | 1 | 813,100 | 0 | 0 | |
| Zai Lab ADR | ADR | 98887Q104 | 63,275 | 1,521,400 | SH | DFND | 2 | 710,700 | 0 | 810,700 | |
| Zai Lab ADR | ADR | 98887Q104 | 14,573 | 350,400 | SH | DFND | 3 | 131,000 | 0 | 219,400 | |
| Zai Lab ADR | ADR | 98887Q104 | 14,756 | 354,800 | SH | SOLE | 0 | 354,800 | 0 | 0 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 46,410 | 1,014,643 | SH | DFND | 1 | 1,014,643 | 0 | 0 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 85,141 | 1,861,404 | SH | DFND | 2 | 1,729,712 | 0 | 131,692 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 4,193 | 91,676 | SH | DFND | 3 | 67,706 | 0 | 23,970 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 29,450 | 643,860 | SH | SOLE | 0 | 627,710 | 0 | 16,150 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 97,114 | 2,113,942 | SH | DFND | 1 | 2,113,942 | 0 | 0 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 221,188 | 4,814,717 | SH | DFND | 2 | 3,800,675 | 0 | 1,014,042 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 151,240 | 3,292,116 | SH | SOLE | 0 | 3,080,801 | 0 | 211,315 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 49,733 | 1,082,573 | SH | DFND | 3 | 811,201 | 0 | 271,372 | |
| Zoom Video Communications Inc | CL A | 98980L101 | 51,768 | 760,846 | SH | DFND | 1 | 760,846 | 0 | 0 | |
| Zoom Video Communications Inc | CL A | 98980L101 | 49,484 | 727,279 | SH | DFND | 2 | 727,279 | 0 | 0 | |
| Zoom Video Communications Inc | CL A | 98980L101 | 2,156 | 31,693 | SH | DFND | 3 | 23,365 | 0 | 8,328 | |
| Zoom Video Communications Inc | CL A | 98980L101 | 64,198 | 943,527 | SH | SOLE | 0 | 943,527 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 6,938 | 484,179 | SH | DFND | 1 | 484,179 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 1,768 | 123,399 | SH | DFND | 3 | 123,399 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 4,977 | 347,303 | SH | DFND | 2 | 122,819 | 0 | 224,484 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 3,515 | 245,311 | SH | SOLE | 0 | 245,311 | 0 | 0 | |
| iRobot | COM | 462726100 | 9,018 | 178,121 | SH | DFND | 1 | 178,121 | 0 | 0 | |
| iRobot | COM | 462726100 | 16,257 | 321,092 | SH | SOLE | 0 | 321,092 | 0 | 0 | |
| iRobot | COM | 462726100 | 5,145 | 101,611 | SH | DFND | 3 | 89,498 | 0 | 12,113 | |
| iRobot | COM | 462726100 | 10,887 | 215,040 | SH | DFND | 2 | 82,952 | 0 | 132,088 | |