The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACORDA THERAPEUTICS INC COM 00484M106 6,275 2,186,257 SH   DFND   0 2,186,257 0
ACORDA THERAPEUTICS INC NOTE 1.750% 6/1 00484MAA4 39,319 49,764,825 PRN   DFND   0 49,764,825 0
ADVANCED MICRO DEVICES INC COM 007903107 25,803 890,079 SH   DFND   0 890,079 0
AERIE PHARMACEUTICALS INC COM 00771V108 35,190 1,830,924 SH   DFND   0 1,830,924 0
ALEXION PHARMACEUTICALS INC COM 015351109 141,681 1,446,612 SH   DFND   0 1,446,612 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 13,580 81,204 SH   DFND   0 81,204 0
ALLENA PHARMACEUTICALS INC COM 018119107 1,919 486,978 SH   DFND   0 486,978 0
ALLERGAN PLC SHS G0177J108 76,673 455,598 SH   DFND   0 455,598 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 103,968 2,271,536 SH   DFND   0 2,271,536 0
ASSETMARK FINL HLDGS INC COM 04546L106 762 29,259 SH   DFND   0 29,259 0
AUDENTES THERAPEUTICS INC COM 05070R104 65,055 2,315,938 SH   DFND   0 2,315,938 0
AVROBIO INC COM 05455M100 11,070 783,975 SH   DFND   0 783,975 0
AXONICS MODULATION TECH INC COM 05465P101 6,769 251,461 SH   DFND   0 251,461 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 144,846 2,149,051 SH   DFND   0 2,149,051 0
CARDIOVASCULAR SYS INC DEL COM 141619106 22,099 465,045 SH   DFND   0 465,045 0
CATALENT INC COM 148806102 52,749 1,106,773 SH   DFND   0 1,106,773 0
CIGNA CORP NEW COM 125523100 60,364 397,684 SH   DFND   0 397,684 0
COHERUS BIOSCIENCES INC COM 19249H103 13,976 689,825 SH   DFND   0 689,825 0
COUPA SOFTWARE INC COM 22266L106 21,680 167,323 SH   DFND   0 167,323 0
DELPHI TECHNOLOGIES PLC SHS G2709G107 5,755 429,452 SH   DFND   0 429,452 0
DERMIRA INC COM 24983L104 24,471 3,829,536 SH   DFND   0 3,829,536 0
DERMIRA INC NOTE 3.000% 5/1 24983LAB0 25,585 30,558,000 PRN   DFND   0 30,558,000 0
DEXCOM INC COM 252131107 63,911 428,242 SH   DFND   0 428,242 0
EDWARDS LIFESCIENCES CORP COM 28176E108 55,363 251,754 SH   DFND   0 251,754 0
EIDOS THERAPEUTICS INC COM 28249H104 4,539 126,181 SH   DFND   0 126,181 0
ENDOLOGIX INC COM NEW 29266S304 1,008 253,890 SH   DFND   0 253,890 0
EQUILLIUM INC COM 29446K106 4,047 1,064,979 SH   DFND   0 1,064,979 0
FATE THERAPEUTICS INC COM 31189P102 13,682 881,002 SH   DFND   0 881,002 0
FLUIDIGM CORP DEL COM 34385P108 14,395 3,109,179 SH   DFND   0 3,109,179 0
GILEAD SCIENCES INC COM 375558103 116,864 1,843,860 SH   DFND   0 1,843,860 0
GODADDY INC CL A 380237107 47,753 723,756 SH   DFND   0 723,756 0
GOLDMAN SACHS GROUP INC COM 38141G104 9,806 47,320 SH   DFND   0 47,320 0
HCA HEALTHCARE INC COM 40412C101 50,183 416,733 SH   DFND   0 416,733 0
ICON PLC SHS G4705A100 34,945 237,175 SH   DFND   0 237,175 0
INSPIRE MED SYS INC COM 457730109 21,410 350,870 SH   DFND   0 350,870 0
INTUIT COM 461202103 47,896 180,102 SH   DFND   0 180,102 0
IQVIA HLDGS INC COM 46266C105 71,255 477,002 SH   DFND   0 477,002 0
IRHYTHM TECHNOLOGIES INC COM 450056106 80,117 1,081,059 SH   DFND   0 1,081,059 0
KARUNA THERAPEUTICS INC COM 48576A100 6,702 410,643 SH   DFND   0 410,643 0
LIVE NATION ENTERTAINMENT IN COM 538034109 13,092 197,341 SH   DFND   0 197,341 0
LIVONGO HEALTH INC COM 539183103 1,855 106,380 SH   DFND   0 106,380 0
MCKESSON CORP COM 58155Q103 22,877 167,400 SH Call DFND   0 167,400 0
MICROCHIP TECHNOLOGY INC COM 595017104 77,161 830,494 SH   DFND   0 830,494 0
MICROSOFT CORP COM 594918104 34,841 250,603 SH   DFND   0 250,603 0
MIRATI THERAPEUTICS INC COM 60468T105 33,589 431,123 SH   DFND   0 431,123 0
MKS INSTRUMENT INC COM 55306N104 27,833 301,611 SH   DFND   0 301,611 0
MOLINA HEALTHCARE INC COM 60855R100 53,960 491,797 SH   DFND   0 491,797 0
MYOKARDIA INC COM 62857M105 64,007 1,227,371 SH   DFND   0 1,227,371 0
NEVRO CORP COM 64157F103 34,067 396,270 SH   DFND   0 396,270 0
NOVARTIS A G SPONSORED ADR 66987V109 59,678 689,600 SH   DFND   0 689,600 0
NOVO-NORDISK A S ADR K72807132 399,188 1,133,574 SH   DFND   0 1,133,574 0
NXP SEMICONDUCTORS N V COM N6596X109 77,468 709,930 SH   DFND   0 709,930 0
PAYPAL HLDGS INC COM 70450Y103 1,578 15,236 SH   DFND   0 15,236 0
PENUMBRA INC COM 70975L107 138,466 1,029,564 SH   DFND   0 1,029,564 0
PRINCIPIA BIOPHARMA INC COM 74257L108 15,802 559,553 SH   DFND   0 559,553 0
PTC THERAPEUTICS INC COM 69366J200 55,946 1,654,225 SH   DFND   0 1,654,225 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 20,605 19,807,000 PRN   DFND   0 19,807,000 0
PUMA BIOTECHNOLOGY INC COM 74587V107 39,718 3,689,538 SH   DFND   0 3,689,538 0
SAGE THERAPEUTICS INC COM 78667J108 52,444 373,828 SH   DFND   0 373,828 0
SALESFORCE COM INC COM 79466L302 52,017 350,422 SH   DFND   0 350,422 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 87,200 1,143,600 SH Put DFND   0 1,143,600 0
STRYKER CORP COM 863667101 44,966 207,887 SH   DFND   0 207,887 0
TRADEWEB MKTS INC CL A 892672106 2,483 67,157 SH   DFND   0 67,157 0
TWILIO INC CL A 90138F102 58,816 534,889 SH   DFND   0 534,889 0
TWITTER INC COM 90184L102 19,685 477,780 SH   DFND   0 477,780 0
UNIQURE NV SHS N90064101 45,606 1,158,694 SH   DFND   0 1,158,694 0
VISA INC COM CL A 92826C839 23,082 134,188 SH   DFND   0 134,188 0
VISTEON CORP COM NEW 92839U206 12,347 149,584 SH   DFND   0 149,584 0
VOYAGER THERAPEUTICS INC COM 92915B106 21,202 1,231,954 SH   DFND   0 1,231,954 0
WELLCARE HEALTH PLANS INC COM 94946T106 68,324 263,626 SH   DFND   0 263,626 0
WESTERN DIGITAL CORP COM 958102105 47,469 795,919 SH   DFND   0 795,919 0
ZIMMER BIOMET HLDGS INC COM 98956P102 135,601 987,842 SH   DFND   0 987,842 0