The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 432 12,005 SH   SOLE   12,005 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 973 9,933 SH   SOLE   9,933 0 0
ALKERMES PLC SHS G01767105 227 11,632 SH   SOLE   11,632 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 1,100 13,684 SH   SOLE   13,684 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 510 33,641 SH   SOLE   33,641 0 0
AMGEN INC COM 031162100 294 1,518 SH   SOLE   1,518 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 447 9,770 SH   SOLE   9,770 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 596 6,190 SH   SOLE   6,190 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 487 17,339 SH   SOLE   17,339 0 0
BIO TECHNE CORP COM 09073M104 303 1,551 SH   SOLE   1,551 0 0
BIOGEN INC COM 09062X103 261 1,123 SH   SOLE   1,123 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 453 10,852 SH   SOLE   10,852 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 654 9,700 SH   SOLE   9,700 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 498 6,780 SH   SOLE   6,780 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 1,673 33,000 SH   SOLE   33,000 0 0
ISHARES TR NASDAQ BIOTECH 464287556 8,458 85,000 SH Call SOLE   85,000 0 0
CELGENE CORP COM 151020104 559 5,625 SH   SOLE   5,625 0 0
CHARLES RIV LABS INTL INC COM 159864107 280 2,112 SH   SOLE   2,112 0 0
CHECKPOINT THERAPEUTICS INC COM 162828107 281 112,760 SH   SOLE   112,760 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 542 13,214 SH   SOLE   13,214 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 632 18,631 SH   SOLE   18,631 0 0
DIREXION SHS ETF TR SP BIOTCH BL NEW 25490K323 3,086 99,855 SH   SOLE   99,855 0 0
EPIZYME INC COM 29428V104 520 50,378 SH   SOLE   50,378 0 0
EXACT SCIENCES CORP COM 30063P105 771 8,534 SH   SOLE   8,534 0 0
EXELIXIS INC COM 30161Q104 232 13,132 SH   SOLE   13,132 0 0
FIBROGEN INC COM 31572Q808 212 5,742 SH   SOLE   5,742 0 0
FORTRESS BIOTECH INC COM 34960Q109 865 613,551 SH   SOLE   613,551 0 0
G1 THERAPEUTICS INC COM 3621LQ109 475 20,844 SH   SOLE   20,844 0 0
GILEAD SCIENCES INC COM 375558103 259 4,082 SH   SOLE   4,082 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 460 9,479 SH   SOLE   9,479 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 264 13,196 SH   SOLE   13,196 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 423 3,674 SH   SOLE   3,674 0 0
ILLUMINA INC COM 452327109 1,436 4,721 SH   SOLE   4,721 0 0
INCYTE CORP COM 45337C102 791 10,659 SH   SOLE   10,659 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 380 28,490 SH   SOLE   28,490 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 261 3,926 SH   SOLE   3,926 0 0
IONIS PHARMACEUTICALS INC COM 462222100 1,206 20,124 SH   SOLE   20,124 0 0
IQVIA HLDGS INC COM 46266C105 297 1,985 SH   SOLE   1,985 0 0
ISHARES TR NASDAQ BIOTECH 464287556 12,438 125,000 SH   SOLE   125,000 0 0
LIGAND PHARMACEUTICALS INC COM NEW 53220K504 242 2,428 SH   SOLE   2,428 0 0
MACROGENICS INC COM 556099109 384 30,075 SH   SOLE   30,075 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 2,279 3,235 SH   SOLE   3,235 0 0
NEKTAR THERAPEUTICS COM 640268108 235 12,927 SH   SOLE   12,927 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 282 3,127 SH   SOLE   3,127 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109 798 138,461 SH   SOLE   138,461 0 0
QIAGEN NV SHS NEW N72482123 951 28,858 SH   SOLE   28,858 0 0
RECRO PHARMA INC COM 75629F109 126 11,353 SH   SOLE   11,353 0 0
REGENERON PHARMACEUTICALS COM 75886F107 677 2,439 SH   SOLE   2,439 0 0
SEATTLE GENETICS INC COM 812578102 1,539 18,020 SH   SOLE   18,020 0 0
SPARK THERAPEUTICS INC COM 84652J103 941 9,699 SH   SOLE   9,699 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 217 5,064 SH   SOLE   5,064 0 0
UNIQURE NV SHS N90064101 560 14,215 SH   SOLE   14,215 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 279 3,498 SH   SOLE   3,498 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 1,403 8,279 SH   SOLE   8,279 0 0
ZOGENIX INC COM NEW 98978L204 389 9,725 SH   SOLE   9,725 0 0