The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACADIA PHARMACEUTICALS INC | Common | 004225108 | 31,941 | 887,500 | SH | SOLE | 887,500 | 0 | 0 | ||
| ADVERUM BIOTECHNOLOGIES INC | Common | 00773U108 | 23,163 | 4,250,000 | SH | SOLE | 4,250,000 | 0 | 0 | ||
| ALIMERA SCIENCES INC | Common | 016259103 | 3,534 | 6,240,000 | SH | SOLE | 6,240,000 | 0 | 0 | ||
| ALLOGENE THERAPEUTICS INC | Common | 019770106 | 30,760 | 1,128,594 | SH | SOLE | 1,128,594 | 0 | 0 | ||
| AMARIN CORP PLC | Sponsored ADR | 023111206 | 129,163 | 8,520,000 | SH | SOLE | 8,520,000 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | Common | 03152W109 | 89,022 | 11,100,000 | SH | SOLE | 11,100,000 | 0 | 0 | ||
| ARGENX SE | Sponsored ADR | 04016X101 | 95,157 | 835,000 | SH | SOLE | 835,000 | 0 | 0 | ||
| ASCENDIS PHARMA | Sponsored ADR | 04351P101 | 189,750 | 1,970,000 | SH | SOLE | 1,970,000 | 0 | 0 | ||
| ATHENEX INC | Common | 04685N103 | 71,652 | 5,890,000 | SH | SOLE | 5,890,000 | 0 | 0 | ||
| BIODELIVERY SCIENCES INTL | Common | 09060J106 | 31,259 | 7,424,867 | SH | SOLE | 7,424,867 | 0 | 0 | ||
| BIOMARIN PHARMACEUTICAL INC | Common | 09061G101 | 164,261 | 2,437,100 | SH | SOLE | 2,437,100 | 0 | 0 | ||
| CYMABAY THERAPEUTICS INC | Common | 23257D103 | 13,824 | 2,700,000 | SH | SOLE | 2,700,000 | 0 | 0 | ||
| FENNEC PHARMACEUTICALS INC | Common | 31447P100 | 5,320 | 1,105,999 | SH | SOLE | 1,105,999 | 0 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS INC | Common | 37890U108 | 48,520 | 1,000,000 | SH | SOLE | 1,000,000 | 0 | 0 | ||
| HORIZON THERAPEUTICS PLC | Common | G46188101 | 108,920 | 4,000,000 | SH | SOLE | 4,000,000 | 0 | 0 | ||
| IMMUNOMEDICS INC | Common | 452907108 | 278,460 | 21,000,000 | SH | SOLE | 21,000,000 | 0 | 0 | ||
| IOVANCE BIOTHERAPEUTICS INC | Common | 462260100 | 192,939 | 10,601,039 | SH | SOLE | 10,601,039 | 0 | 0 | ||
| KARYOPHARM THERAPEUTICS INC | Common | 48576U106 | 58,201 | 6,050,000 | SH | SOLE | 6,050,000 | 0 | 0 | ||
| KODIAK SCIENCES INC | Common | 50015M109 | 7,190 | 500,000 | SH | SOLE | 500,000 | 0 | 0 | ||
| MADRIGAL PHARMACEUTICALS INC | Common | 558868105 | 31,039 | 360,000 | SH | SOLE | 360,000 | 0 | 0 | ||
| MEDICINES CO | Common | 584688105 | 18,581 | 371,623 | SH | SOLE | 371,623 | 0 | 0 | ||
| MIRATI THERAPEUTICS INC | Common | 60468T105 | 292,163 | 3,750,000 | SH | SOLE | 3,750,000 | 0 | 0 | ||
| MYOKARDIA INC | Common | 62857M105 | 80,973 | 1,552,700 | SH | SOLE | 1,552,700 | 0 | 0 | ||
| PACIRA BIOSCIENCES INC | Common | 695127100 | 60,912 | 1,600,000 | SH | SOLE | 1,600,000 | 0 | 0 | ||
| PTC THERAPEUTICS INC | Common | 69366J200 | 23,133 | 684,000 | SH | SOLE | 684,000 | 0 | 0 | ||
| ROCKET PHARMACEUTICALS INC | Common | 77313F106 | 3,329 | 285,714 | SH | SOLE | 285,714 | 0 | 0 | ||
| SAREPTA THERAPEUTICS INC | Common | 803607100 | 126,387 | 1,678,000 | SH | SOLE | 1,678,000 | 0 | 0 | ||
| TELIGENT INC | Common | 87960W104 | 4,970 | 5,231,206 | SH | SOLE | 5,231,206 | 0 | 0 | ||
| TRICIDA INC | Common | 89610F101 | 67,914 | 2,200,000 | SH | SOLE | 2,200,000 | 0 | 0 | ||
| TURNING POINT THERAPEUTICS INC | Common | 90041T108 | 3,760 | 100,000 | SH | SOLE | 100,000 | 0 | 0 | ||
| UNIQURE NV | Common | N90064101 | 14,366 | 365,000 | SH | SOLE | 365,000 | 0 | 0 | ||
| XENON PHARMACEUTICALS INC | Common | 98420N105 | 21,624 | 2,400,000 | SH | SOLE | 2,400,000 | 0 | 0 | ||
| ZOGENIX INC | Common | 98978L204 | 75,075 | 1,875,000 | SH | SOLE | 1,875,000 | 0 | 0 | ||