The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100 7,296 87,198 SH   SOLE   87,198 0 0
ACCELERON PHARMA COM 00434H108 8,992 227,596 SH   SOLE   78,899 0 148,697
AERIE PHARMACEUTIC COM 00771V108 20,979 1,091,534 SH   SOLE   532,750 0 558,784
AGIOS PHARMACEUTIC COM 00847X104 1,471 45,400 SH   SOLE   45,400 0 0
ALBIREO PHARMA INC COM 01345P106 2,944 147,211 SH   SOLE   83,249 0 63,962
ALEXION PHARM INC COM 015351109 3,594 36,699 SH   SOLE   36,699 0 0
ALNYLAM PHARMACUETCL COM 02043Q107 14,825 184,341 SH   SOLE   61,141 0 123,200
AMICUS THERAPEUTICS COM 03152W109 27,604 3,441,922 SH   SOLE   1,264,865 0 2,177,057
APELLIS PHARMACEUTIC COM 03753U106 24,017 996,983 SH   SOLE   696,220 0 300,763
ASSEMBLY BIOSCIENCES COM 045396108 7,077 719,896 SH   SOLE   459,496 0 260,400
ATRICURE INC COM 04963C209 11,160 447,455 SH   SOLE   103,761 0 343,694
BIOMARIN PHARMAC INC COM 09061G101 9,557 141,801 SH   SOLE   141,801 0 0
BOSTON SCIENTIFIC COM 101137107 9,040 222,176 SH   SOLE   222,176 0 0
BRISTOL MYERS SQUIBB COM 110122108 14,229 280,597 SH   SOLE   280,597 0 0
CIGNA CORP COM 125523100 9,474 62,413 SH   SOLE   62,413 0 0
CHANGE HEALTHCARE IN COM 15912K100 4,901 405,750 SH   SOLE   190,042 0 215,708
COLLEGIUM PHARMACEUT COM 19459J104 10,392 905,247 SH   SOLE   404,091 0 501,156
DR REDDYS LABS LTD ADR 256135203 1,493 39,397 SH   SOLE   39,397 0 0
EVELO BIOSCIENCES COM 299734103 4,469 732,582 SH   SOLE   276,029 0 456,553
EVOLENT HEALTH INC COM 30050B101 11,402 1,585,752 SH   SOLE   639,500 0 946,252
FIBROGEN INC COM 31572Q808 12,331 333,460 SH   SOLE   130,000 0 203,460
FORTY SEVEN INC COM 34983P104 5,229 814,414 SH   SOLE   387,464 0 426,950
GILEAD SCIENCES INC COM 375558103 15,651 246,940 SH   SOLE   246,940 0 0
GLOBAL BLOOD THERA COM 37890U108 11,695 241,040 SH   SOLE   80,287 0 160,753
HMS HOLDINGS CORP COM 40425J101 2,679 77,725 SH   SOLE   225 0 77,500
HILL-ROM HLDS INC COM 431475102 9,271 88,099 SH   SOLE   0 0 88,099
HOMOLOGY MEDICINES COM 438083107 1,346 74,381 SH   SOLE   74,381 0 0
IRHYTHM TECHNOLOGIES COM 450056106 13,914 187,750 SH   SOLE   53,550 0 134,200
IMMUNOMEDICS INC COM 452907108 12,064 909,822 SH   SOLE   277,603 0 632,219
INSPIRE MED SYS INC COM 457730109 16,054 263,100 SH   SOLE   102,400 0 160,700
LA JOLLA PHARMACLS COM 503459604 10,193 1,158,271 SH   SOLE   483,327 0 674,944
LILLY ELI & CO COM 532457108 6,236 55,765 SH   SOLE   55,765 0 0
MERCK & CO INC COM 58933Y105 9,900 117,600 SH   SOLE   117,600 0 0
MOLECULAR TEMPLATES COM 608550109 1,942 294,615 SH   SOLE   294,615 0 0
NOVARTIS AG SPONSORED ADR 66987V109 12,848 147,846 SH   SOLE   147,846 0 0
PTC THERAPEUTICS I COM 69366J200 12,758 377,238 SH   SOLE   162,181 0 215,057
PFIZER INC COM 717081103 6,594 183,528 SH   SOLE   183,528 0 0
PHASEBIO PHARMACEU COM 717224109 817 196,000 SH   SOLE   196,000 0 0
PORTOLA PHARMACEUTIC COM 737010108 14,657 546,489 SH   SOLE   148,047 0 398,442
RA PHARMACEUTICALS COM 74933V108 10,672 451,247 SH   SOLE   189,324 0 261,923
R1 RCM INC COM 749397105 8,837 989,572 SH   SOLE   218,772 0 770,800
SAGE THERAPEUTICS COM 78667J108 1,473 10,500 SH   SOLE   10,500 0 0
SAREPTA THERAPEUTICS COM 803607100 6,357 84,398 SH   SOLE   48,300 0 36,098
SAVARA INC COM 805111101 1,882 710,310 SH   SOLE   443,902 0 266,408
SHOCKWAVE MEDICAL COM 82489T104 17,163 573,434 SH   SOLE   573,434 0 0
SPRING BK PHARMACE COM 849431101 952 276,656 SH   SOLE   276,656 0 0
STEMLINE THERAPEUT COM 85858C107 7,055 677,759 SH   SOLE   372,559 0 305,200
TABULA RASA HEALTH COM 873379101 6,626 120,600 SH   SOLE   200 0 120,400
TANDEM DIABETES CARE COM 875372203 25,527 432,815 SH   SOLE   130,315 0 302,500
TELADOC HEALTH COM 87918A105 35,588 525,511 SH   SOLE   140,755 0 384,756
THERMO FISHER SCI COM 883556102 5,301 18,200 SH   SOLE   18,200 0 0
UNUM THERAPEUTICS COM 903214104 2,188 1,519,174 SH   SOLE   793,746 0 725,428
VERTEX PHARMACEUTICL COM 92532F100 2,401 14,171 SH   SOLE   14,171 0 0
VIEWRAY INC COM 92672L107 3,599 1,240,865 SH   SOLE   381,070 0 859,795
VOCERA COMMUNICATI COM 92857F107 11,801 478,728 SH   SOLE   133,146 0 345,582
ZIMMER BIOMET HLDS COM 98956P102 9,142 66,598 SH   SOLE   66,598 0 0
ALLERGAN PLC SHS G0177J108 808 4,800 SH   SOLE   4,800 0 0
MEDTRONIC PLC SHS G5960L103 7,891 72,651 SH   SOLE   72,651 0 0
MEIRAGTX HLDINGS PLC COM G59665102 3,275 205,306 SH   SOLE   205,306 0 0
OBSEVA SA COM H5861P103 5,357 643,151 SH   SOLE   643,151 0 0
UROGEN PHARMA LTD COM M96088105 1,550 65,063 SH   SOLE   65,063 0 0
UNIQURE N.V. SHS N90064101 1,161 29,500 SH   SOLE   29,500 0 0
WRIGHT MED GROUP N V ORD SHS N96617118 21,948 1,063,872 SH   SOLE   376,100 0 687,772