The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abbott Laboratories COM 002824100 18,417 220,114 SH   SOLE   0 0 220,114
AbbVie Inc COM 00287Y109 12,872 170,000 SH   SOLE   0 0 170,000
Abeona Therapeutics Inc Reg COM 00289Y107 2,260 1,000,000 SH   SOLE   0 0 1,000,000
Abiomed Inc COM 003654100 21,347 120,000 SH   SOLE   0 0 120,000
Acceleron Pharma Inc Reg COM 00434H108 2,766 70,000 SH   SOLE   0 0 70,000
Achillion Pharmaceuticals Inc COM 00448Q201 1,000 277,800 SH   SOLE   0 0 277,800
Adverum Biotechnologies Inc COM 00773U108 652 119,673 SH   SOLE   0 0 119,673
Aerie Pharmaceuticals Inc COM 00771V108 9,130 475,000 SH   SOLE   0 0 475,000
Agios Pharmaceuticals Inc COM 00847X104 7,938 245,002 SH   SOLE   0 0 245,002
Aimmune Therapeutics Inc Reg COM 00900T107 3,124 149,201 SH   SOLE   0 0 149,201
Alexion Pharmaceuticals Inc COM 015351109 24,221 247,303 SH   SOLE   0 0 247,303
Alkermes Plc SHS G01767105 4,292 220,000 SH   SOLE   0 0 220,000
Alnylam Pharmaceuticals Inc COM 02043Q107 5,549 69,000 SH   SOLE   0 0 69,000
Amarin Corp Plc spons ADR repr 1 Share SPONS ADR NEW 023111206 6,064 400,000 SH   SOLE   0 0 400,000
AmerisourceBergen Corp COM 03073E105 8,151 99,000 SH   SOLE   0 0 99,000
Anheuser-Busch InBev SA ADR spons repr 1 Share SPONSORED ADR 03524A108 324 3,409 SH   SOLE   0 0 3,409
Anthem Inc COM 036752103 14,406 60,000 SH   SOLE   0 0 60,000
Arena Pharmaceuticals Inc Reg COM NEW 040047607 7,094 155,000 SH   SOLE   0 0 155,000
ArQule Inc Reg COM 04269E107 1,434 200,000 SH   SOLE   0 0 200,000
Becton Dickinson & Co COM 075887109 15,936 63,000 SH   SOLE   0 0 63,000
BioMarin Pharmaceutical Inc COM 09061G101 19,579 290,491 SH   SOLE   0 0 290,491
Bluebird Bio Inc COM 09609G100 4,775 52,000 SH   SOLE   0 0 52,000
Boston Scientific Corp COM 101137107 15,055 370,000 SH   SOLE   0 0 370,000
Bristol Myers Squibb Co COM 110122108 21,045 415,000 SH   SOLE   0 0 415,000
Centene Corp COM 15135B101 7,571 175,000 SH   SOLE   0 0 175,000
Chevron Corp COM 166764100 353 2,974 SH   SOLE   0 0 2,974
Cigna Corp Reg COM 125523100 12,143 80,000 SH   SOLE   0 0 80,000
Coherus BioSciences Inc COM 19249H103 5,875 290,000 SH   SOLE   0 0 290,000
CVS Health Corp COM 126650100 19,159 303,768 SH   SOLE   0 0 303,768
Dermira Inc Reg COM 24983L104 3,510 549,300 SH   SOLE   0 0 549,300
Diplomat Pharmacy Inc Reg COM 25456K101 5,194 1,060,000 SH   SOLE   0 0 1,060,000
Dynavax Technologies Corp COM NEW 268158201 4,413 1,234,335 SH   SOLE   0 0 1,234,335
Edwards Lifesciences Corp COM 28176E108 8,045 36,585 SH   SOLE   0 0 36,585
Eli Lilly & Co COM 532457108 16,775 150,000 SH   SOLE   0 0 150,000
Epizyme Inc Reg COM 29428V104 4,642 450,028 SH   SOLE   0 0 450,028
Esperion Therapeutics Inc COM 29664W105 24,044 655,854 SH   SOLE   0 0 655,854
Exact Sciences Corp Reg COM 30063P105 9,741 107,786 SH   SOLE   0 0 107,786
Exelixis Inc COM 30161Q104 5,659 320,000 SH   SOLE   0 0 320,000
Exxon Mobil Corp COM 30231G102 272 3,854 SH   SOLE   0 0 3,854
FibroGen Inc COM 31572Q808 10,909 295,000 SH   SOLE   0 0 295,000
Ford Motor Co COM 345370860 267 29,164 SH   SOLE   0 0 29,164
G1 Therapeutics Inc Reg COM 3621LQ109 12,202 535,657 SH   SOLE   0 0 535,657
Glaukos Corp COM 377322102 14,352 229,600 SH   SOLE   0 0 229,600
Guardant Health Inc Reg COM 40131M109 2,234 35,000 SH   SOLE   0 0 35,000
HCA Healthcare Inc COM 40412C101 9,032 75,000 SH   SOLE   0 0 75,000
HMS Holdings Corp Reg COM 40425J101 3,388 98,300 SH   SOLE   0 0 98,300
Horizon Therapeutics Plc SHS G46188101 27,911 1,025,000 SH   SOLE   0 0 1,025,000
Humana Inc COM 444859102 15,340 60,000 SH   SOLE   0 0 60,000
IBM Corp COM 459200101 322 2,215 SH   SOLE   0 0 2,215
Immunomedics Inc COM 452907108 11,271 850,000 SH   SOLE   0 0 850,000
Incyte Corp Ltd COM 45337CAN2 5,938 80,000 SH   SOLE   0 0 80,000
Intercept Pharmaceuticals Inc COM 45845P108 3,159 47,600 SH   SOLE   0 0 47,600
Intra-Cellular Therapies Inc COM 46116X101 6,350 850,000 SH   SOLE   0 0 850,000
Iovance Biotherapeutics Inc Reg COM 462260100 9,464 520,000 SH   SOLE   0 0 520,000
Janus Henderson Group Plc Reg ORD SHS G4474Y214 239 10,645 SH   SOLE   0 0 10,645
Jazz Pharmaceuticals Plc SHS USD G50871105 19,221 150,000 SH   SOLE   0 0 150,000
JPMorgan Chase & Co COM 46625H100 291 2,472 SH   SOLE   0 0 2,472
Livanova Plc SHS G5509L101 8,855 120,000 SH   SOLE   0 0 120,000
Macrogenics Inc COM 556099109 10,200 799,373 SH   SOLE   0 0 799,373
Madrigal Pharmaceuticals Inc Reg COM 558868105 2,587 30,000 SH   SOLE   0 0 30,000
Medicines Co COM 584688105 7,650 153,000 SH   SOLE   0 0 153,000
Medtronic Plc Reg SHS G5960L103 20,118 185,218 SH   SOLE   0 0 185,218
Merck & Co Inc COM 58933Y105 18,099 215,000 SH   SOLE   0 0 215,000
Microsoft Corp COM 594918104 213 1,532 SH   SOLE   0 0 1,532
Mirati Therapeutics Inc Reg COM 60468T105 7,791 100,000 SH   SOLE   0 0 100,000
MyoKardia Inc Reg COM 62857M105 10,430 200,000 SH   SOLE   0 0 200,000
NanoString Technologies Inc Reg COM 63009R109 3,069 142,126 SH   SOLE   0 0 142,126
Nektar Therapeutics COM 640268108 21,858 1,200,000 SH   SOLE   0 0 1,200,000
Neurocrine Biosciences Inc COM 64125C109 13,480 149,600 SH   SOLE   0 0 149,600
NovoCure Ltd Reg ORD SHS G6674U108 25,425 340,000 SH   SOLE   0 0 340,000
Omnicell Inc COM 68213N109 6,504 90,000 SH   SOLE   0 0 90,000
Pieris Pharmaceuticals Inc Reg COM 720795103 1,023 300,000 SH   SOLE   0 0 300,000
Qualcomm Inc COM 747525103 259 3,391 SH   SOLE   0 0 3,391
Ra Pharmaceuticals Inc Reg COM 74933V108 5,771 244,000 SH   SOLE   0 0 244,000
Radius Health Inc Reg COM NEW 750469207 3,863 150,000 SH   SOLE   0 0 150,000
Regeneron Pharmaceuticals Inc COM 75886F107 12,492 45,031 SH   SOLE   0 0 45,031
Revance Therapeutics Inc COM 761330109 2,261 173,917 SH   SOLE   0 0 173,917
Rigel Pharmaceuticals Inc COM NEW 766559603 3,740 2,000,000 SH   SOLE   0 0 2,000,000
Sage Therapeutics Inc COM 78667J108 2,806 20,000 SH   SOLE   0 0 20,000
Sangamo Therapeutics Inc Reg COM 800677106 6,650 734,811 SH   SOLE   0 0 734,811
Seattle Genetics Inc Reg COM 812578102 12,699 148,700 SH   SOLE   0 0 148,700
Silk Road Medical Inc Reg COM 82710M100 4,066 125,000 SH   SOLE   0 0 125,000
Stemline Therapeutics Inc Reg COM 85858C107 5,320 511,023 SH   SOLE   0 0 511,023
Sunesis Pharmaceuticals Inc Reg COM 867328700 272 377,244 SH   SOLE   0 0 377,244
Symantec Corp COM 871503108 207 8,761 SH   SOLE   0 0 8,761
The Walt Disney Co COM DISNEY 254687106 271 2,083 SH   SOLE   0 0 2,083
Thermo Fisher Scientific Inc COM 883556102 11,068 38,000 SH   SOLE   0 0 38,000
United Health Group Inc COM 91324P102 16,734 77,000 SH   SOLE   0 0 77,000
Wells Fargo & Co COM 949746101 266 5,272 SH   SOLE   0 0 5,272
Vertex Pharmaceuticals Inc COM 92532F100 31,512 186,000 SH   SOLE   0 0 186,000
ViewRay Inc Reg COM 92672L107 1,843 635,434 SH   SOLE   0 0 635,434
Viking Therapeutics Inc Reg COM 92686J106 1,376 200,000 SH   SOLE   0 0 200,000
Xencor Inc COM 98401F105 10,204 302,523 SH   SOLE   0 0 302,523