The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101 17,334 100,000 SH Put DFND   100,000 0 0
ADAMIS PHARMACEUTICALS CORP COM NEW 00547W208 1,105 850,000 SH   DFND   850,000 0 0
ADECOAGRO S A COM L00849106 2,499 350,000 SH   DFND   350,000 0 0
ADIENT PLC ORD SHS G0084W101 19,707 812,000 SH   DFND   812,000 0 0
ADMA BIOLOGICS INC COM 000899104 5,512 1,424,378 SH   DFND   1,424,378 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 4,268 358,986 SH   DFND   358,986 0 0
AFFIMED N V COM N01045108 575 200,000 SH   DFND   200,000 0 0
AKERNA CORP *W EXP 01/30/202 00973W110 223 75,000 SH   DFND   75,000 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 12,755 2,125,781 SH   DFND   2,125,781 0 0
ALLEGRO MERGER CORP *W EXP 01/06/202 01749N111 124 443,772 SH   DFND   443,772 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 24,670 340,000 SH   DFND   340,000 0 0
AMCI ACQUISITION CORP *W EXP 05/20/202 00165R119 64 200,000 SH   DFND   200,000 0 0
APHRIA INC COM 03765K104 1,052 150,000 SH   DFND   150,000 0 0
APHRIA INC COM 03765K104 1,052 150,000 SH Put DFND   150,000 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 758 200,000 SH   DFND   200,000 0 0
ARDELYX INC COM 039697107 3,880 1,442,346 SH   DFND   1,442,346 0 0
ARYA SCIENCES ACQUISITION CO SHS CL A G3165V109 10,010 1,000,000 SH   DFND   1,000,000 0 0
ARYA SCIENCES ACQUISITION CO *W EXP 10/10/202 G3165V125 750 500,000 SH   DFND   500,000 0 0
AT&T INC COM 00206R102 3,351 100,000 SH Put DFND   100,000 0 0
AZURRX BIOPHARMA INC COM 05502L105 1,182 695,504 SH   DFND   695,504 0 0
BIG ROCK PARTNERS ACQUISI CO *W EXP 12/01/202 089482111 18 82,500 SH   DFND   82,500 0 0
BIG ROCK PARTNERS ACQUISI CO RIGHT 12/01/2022 089482129 31 165,000 SH   DFND   165,000 0 0
BIOCERES CROP SOLUTIONS CORP *W EXP 03/14/202 G1117K106 66 200,000 SH   DFND   200,000 0 0
BLACK RIDGE ACQUISITION CORP *W EXP 07/10/202 09216T115 287 700,000 SH   DFND   700,000 0 0
BLACK RIDGE ACQUISITION CORP RIGHT 07/10/2019 09216T123 84 200,000 SH   DFND   200,000 0 0
BONANZA CREEK ENERGY INC COM NEW 097793400 1,044 50,000 SH   DFND   50,000 0 0
BRIGHTHOUSE FINL INC COM 10922N103 1,101 30,000 SH   DFND   30,000 0 0
CAPITAL ONE FINL CORP COM 14040H105 22,322 246,000 SH   DFND   246,000 0 0
CARDLYTICS INC COM 14161W105 3,064 117,891 SH   DFND   117,891 0 0
CARVANA CO CL A 146869102 122,990 1,965,000 SH   DFND   1,965,000 0 0
CHAPARRAL ENERGY INC COM CL A 15942R208 118 25,023 SH   DFND   25,023 0 0
CHARDAN HEALTHCARE ACQUISITI COM 15957A108 1,469 150,000 SH   DFND   150,000 0 0
CHARDAN HEALTHCARE ACQUISITI *W EXP 12/13/202 15957A116 66 150,000 SH   DFND   150,000 0 0
CHASERG TECHNLGY ACQUISITN C *W EXP 04/10/202 16166A111 56 75,000 SH   DFND   75,000 0 0
CHIMERIX INC COM 16934W106 1,426 330,061 SH   DFND   330,061 0 0
COCA COLA CO COM 191216100 15,276 300,000 SH Put DFND   300,000 0 0
CONCRETE PUMPING HLDGS INC COM 206704108 1,126 220,000 SH   DFND   220,000 0 0
CONSTELLATION ALPHA CAP CORP *W EXP 03/23/202 G2379F116 28 380,000 SH   DFND   380,000 0 0
CONSTELLATION ALPHA CAP CORP RIGHT 99/99/9999 G2379F132 32 180,000 SH   DFND   180,000 0 0
CONTRAFECT CORP COM 212326102 1,276 2,500,000 SH   DFND   2,500,000 0 0
CONTURA ENERGY INC COM 21241B100 3,458 66,625 SH   DFND   66,625 0 0
COOPER STD HLDGS INC COM 21676P103 1,146 25,000 SH   DFND   25,000 0 0
CRESUD S A C I F Y A SPONSORED ADR 226406106 8,875 846,860 SH   DFND   846,860 0 0
DHT HOLDINGS INC SHS NEW Y2065G121 3,044 515,000 SH   DFND   515,000 0 0
DIAMOND S SHIPPING INC COM Y20676105 3,833 300,200 SH   DFND   300,200 0 0
DIANA SHIPPING INC COM Y2066G104 902 272,622 SH   DFND   272,622 0 0
EDTECHX HLDGS ACQUISITION CO *W EXP 12/31/202 28138X111 32 125,000 SH   DFND   125,000 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 19,457 1,835,529 SH   DFND   1,835,529 0 0
ELEVATE CREDIT INC COM 28621V101 881 213,844 SH   DFND   213,844 0 0
ENERGY RECOVERY INC COM 29270J100 11,462 1,100,000 SH   DFND   1,100,000 0 0
ENOVA INTL INC COM 29357K103 15,938 691,426 SH   DFND   691,426 0 0
ESTRE AMBIENTAL INC *W EXP 12/21/202 G3206V118 22 730,000 SH   DFND   730,000 0 0
FALCON MINERALS CORP *W EXP 07/21/202 30607B208 142 149,600 SH   DFND   149,600 0 0
FATE THERAPEUTICS INC COM 31189P102 6,090 300,000 SH   DFND   300,000 0 0
FENNEC PHARMACEUTICALS INC COM 31447P100 3,885 971,351 SH   DFND   971,351 0 0
FERRARI N V COM N3167Y103 8,071 50,000 SH Put DFND   50,000 0 0
FORUM MERGER II CORP *W EXP 09/30/202 34986F111 191 300,000 SH   DFND   300,000 0 0
GALMED PHARMACEUTICALS LTD SHS M47238106 9,923 1,350,000 SH   DFND   1,350,000 0 0
GENCO SHIPPING & TRADING LTD SHS Y2685T131 1,523 180,496 SH   DFND   180,496 0 0
GENERAL MLS INC COM 370334104 5,252 100,000 SH Put DFND   100,000 0 0
GENERAL MTRS CO COM 37045V100 3,853 100,000 SH   DFND   100,000 0 0
GENERAL MTRS CO COM 37045V100 28,898 750,000 SH Call DFND   750,000 0 0
GIGCAPITAL INC RIGHT 03/06/2020 37518N114 104 200,000 SH   DFND   200,000 0 0
GIGCAPITAL INC *W EXP 06/08/202 37518N122 45 150,000 SH   DFND   150,000 0 0
GLOBALSTAR INC COM 378973408 7,400 15,415,778 SH   DFND   15,415,778 0 0
GLOBALSTAR INC NOTE 5.750% 4/0 378973AD3 432 508,004 PRN   DFND   508,004 0 0
GORDON POINTE ACQUISITION CO *W EXP 07/30/202 382788115 77 225,000 SH   DFND   225,000 0 0
GRAF INDL CORP *W EXP 12/31/202 384278115 84 225,000 SH   DFND   225,000 0 0
GREENLAND ACQUISITIN CORPORA *W EXP 03/03/202 G40981105 15 150,000 SH   DFND   150,000 0 0
GREENLAND ACQUISITIN CORPORA RIGHT 04/27/2025 G40981113 59 150,000 SH   DFND   150,000 0 0
GREIF INC CL B 397624206 520 11,910 SH   DFND   11,910 0 0
GRUPO FINANCIERO GALICIA S A SPONSORED ADR 399909100 3,728 105,000 SH   DFND   105,000 0 0
HEALTH SCIENCES ACQUSTN CORP UNIT 04/01/2024 42227C201 8,482 800,000 SH   DFND   800,000 0 0
HERSHEY CO COM 427866108 46,911 350,000 SH Put DFND   350,000 0 0
HL ACQUISITIONS CORP *W EXP 06/21/202 G4603R122 37 180,000 SH   DFND   180,000 0 0
HL ACQUISITIONS CORP RIGHT 07/17/2023 G4603R130 59 180,000 SH   DFND   180,000 0 0
HOSTESS BRANDS INC *W EXP 11/04/202 44109J114 4,788 2,520,000 SH   DFND   2,520,000 0 0
IFRESH INC COM 449538107 37 30,000 SH   DFND   30,000 0 0
INSPIRED ENTMT INC COM 45782N108 6,767 801,824 SH   DFND   801,824 0 0
INTEL CORP COM 458140100 4,787 100,000 SH Put DFND   100,000 0 0
IRSA INVERSIONES Y REP S A GLOBL DEP RCPT 450047204 8,751 894,724 SH   DFND   894,724 0 0
IRSA PROPIEDADES COMERCIALES SPONSORED ADR 463588103 3,328 162,904 SH   DFND   162,904 0 0
JOHNSON & JOHNSON COM 478160104 13,928 100,000 SH Put DFND   100,000 0 0
KADMON HLDGS INC COM 48283N106 690 334,900 SH   DFND   334,900 0 0
KAIXIN AUTO HLDGS SHS G5223X100 39 17,500 SH   DFND   17,500 0 0
KROGER CO COM 501044101 4,451 205,000 SH   DFND   205,000 0 0
KROGER CO COM 501044101 8,684 400,000 SH Call DFND   400,000 0 0
LEAP THERAPEUTICS INC COM 52187K101 268 150,142 SH   DFND   150,142 0 0
LEGACY ACQUISITION CORP *W EXP 11/30/202 524643111 160 500,000 SH   DFND   500,000 0 0
LEISURE ACQUISITION CORP *W EXP 12/05/201 52539T115 71 125,000 SH   DFND   125,000 0 0
LF CAP ACQUISITION CORP *W EXP 06/22/202 50200K116 142 450,000 SH   DFND   450,000 0 0
MACROGENICS INC COM 556099109 9,078 534,970 SH   DFND   534,970 0 0
MAIDEN HOLDINGS LTD SHS G5753U112 5,042 7,876,964 SH   DFND   7,876,964 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 5,811 1,400,000 SH   DFND   1,400,000 0 0
MARKER THERAPEUTICS INC COM 57055L107 4,435 560,000 SH   DFND   560,000 0 0
M D C HLDGS INC COM 552676108 6,556 200,000 SH Put DFND   200,000 0 0
MEDICINES CO COM 584688105 7,841 215,000 SH   DFND   215,000 0 0
MEGALITH FINL ACQUISITION CO *W EXP 08/26/202 58518F117 124 400,000 SH   DFND   400,000 0 0
MEIRAGTX HOLDINGS PLC COM G59665102 10,997 432,319 SH   DFND   432,319 0 0
MICRON TECHNOLOGY INC COM 595112103 13,892 360,000 SH   DFND   360,000 0 0
MIRAGEN THERAPEUTICS INC COM 60463E103 3,620 1,766,038 SH   DFND   1,766,038 0 0
MODERN MEDIA ACQUISITION *W EXP 05/17/202 60765P111 110 500,000 SH   DFND   500,000 0 0
MODERN MEDIA ACQUISITION RIGHT 99/99/9999 60765P129 290 1,000,000 SH   DFND   1,000,000 0 0
MUDRICK CAP ACQUISITION CORP COM CLASS A 624745105 19,342 1,900,000 SH   DFND   1,900,000 0 0
MUDRICK CAP ACQUISITION CORP *W EXP 02/12/202 624745113 1,225 2,500,000 SH   DFND   2,500,000 0 0
MUSTANG BIO INC COM 62818Q104 2,300 625,000 SH   DFND   625,000 0 0
NATIONAL ENERGY SERVICES REU *W EXP 05/05/202 G6375R115 616 725,000 SH   DFND   725,000 0 0
NATIONAL OILWELL VARCO INC COM 637071101 2,890 130,000 SH   DFND   130,000 0 0
NAVIOS MARITIME CONTAINERS L COM UNIT RP LP Y62151108 4,200 2,159,243 SH   DFND   2,159,243 0 0
NAVIOS MARITIME HLDGS INC COM Y62197119 584 130,500 SH   DFND   130,500 0 0
NEW FRONTIER CORP *W EXP 99/99/999 G6485P124 34 50,000 SH   DFND   50,000 0 0
NII HLDGS INC COM PAR 62913F508 22,246 13,163,432 SH   DFND   13,163,432 0 0
NOVUS THERAPEUTICS INC COM 67011N105 326 323,102 SH   DFND   323,102 0 0
NRC GROUP HLDGS CORP *W EXP 10/17/202 629375114 888 537,500 SH   DFND   537,500 0 0
ON DECK CAP INC COM 682163100 13,864 3,340,729 SH   DFND   3,340,729 0 0
ONCONOVA THERAPEUTICS INC COM PAR 68232V405 2,755 966,877 SH   DFND   966,877 0 0
ONCOSEC MED INC COM 68234L306 476 188,000 SH   DFND   188,000 0 0
OPES ACQUISITION CORP *W EXP 03/13/202 68373P118 36 150,000 SH   DFND   150,000 0 0
ORACLE CORP COM 68389X105 34,182 600,000 SH Put DFND   600,000 0 0
OTONOMY INC COM 68906L105 3,025 1,100,000 SH   DFND   1,100,000 0 0
PENN VA CORP NEW COM 70788V102 15,954 520,000 SH   DFND   520,000 0 0
PENSARE ACQUISITION CORP *W EXP 07/27/202 70957E113 17 115,000 SH   DFND   115,000 0 0
PENSARE ACQUISITION CORP RIGHT 99/99/9999 70957E121 91 605,000 SH   DFND   605,000 0 0
PEPSICO INC COM 713448108 13,113 100,000 SH Put DFND   100,000 0 0
PG&E CORP COM 69331C108 44,694 1,950,000 SH   DFND   1,950,000 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 706 150,257 SH   DFND   150,257 0 0
POLARITYTE INC COM 731094108 979 171,733 SH   DFND   171,733 0 0
PROCTER AND GAMBLE CO COM 742718109 10,965 100,000 SH Put DFND   100,000 0 0
RANPAK HLDGS CORP *W EXP 06/03/202 75321W111 157 125,000 SH   DFND   125,000 0 0
REDHILL BIOPHARMA LTD SPONSORED ADS 757468103 24,010 3,693,840 SH   DFND   3,693,840 0 0
ROAN RES INC CL A COM 769755109 2,568 1,475,837 SH   DFND   1,475,837 0 0
SCHULTZE SPL PURP ACQUSTN CO *W EXP 12/31/202 80821R117 90 300,000 SH   DFND   300,000 0 0
SCORPIO TANKERS INC NOTE 3.000% 5/1 80918TAB5 2,075 2,000,000 PRN   DFND   2,000,000 0 0
SCORPIO TANKERS INC SHS Y7542C130 32,030 1,085,000 SH   DFND   1,085,000 0 0
SEADRILL LTD COM G7998G106 3,108 746,951 SH   DFND   746,951 0 0
SELLAS LIFE SCIENCES GROUP I COM 81642T100 408 3,625,000 SH   DFND   3,625,000 0 0
SIERRA ONCOLOGY INC COM 82640U107 1,693 3,023,559 SH   DFND   3,023,559 0 0
SOLENO THERAPEUTICS INC COM NEW 834203200 1,593 569,087 SH   DFND   569,087 0 0
SEQUENTIAL BRNDS GROUP INC N COM 81734P107 1,705 3,100,692 SH   DFND   3,100,692 0 0
STRONGBRIDGE BIOPHARMA PLC SHS USD G85347105 2,891 923,700 SH   DFND   923,700 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 15,045 1,615,955 SH   DFND   1,615,955 0 0
SYNTHETIC BIOLOGICS INC COM NEW 87164U201 24 42,858 SH   DFND   42,858 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 3,980 429,775 SH   DFND   429,775 0 0
TEEKAY TANKERS LTD CL A Y8565N102 1,824 1,425,000 SH   DFND   1,425,000 0 0
TENZING ACQUISITION CORP *W EXP 02/23/202 G8708A108 45 200,000 SH   DFND   200,000 0 0
TESLA INC COM 88160R101 5,587 25,000 SH Call DFND   25,000 0 0
TESLA INC COM 88160R101 85,027 380,500 SH Put DFND   380,500 0 0
TETRAPHASE PHARMACEUTICALS I COM 88165N105 403 840,000 SH   DFND   840,000 0 0
TG THERAPEUTICS INC COM 88322Q108 4,282 495,000 SH   DFND   495,000 0 0
TIBERIUS ACQUISITION CORP *W EXP 02/28/202 88633A115 205 450,000 SH   DFND   450,000 0 0
TKK SYMPHONY ACQUISITION COR *W EXP 02/20/202 G88950129 29 225,000 SH   DFND   225,000 0 0
TKK SYMPHONY ACQUISITION COR RIGHT 02/20/2020 G88950137 41 225,000 SH   DFND   225,000 0 0
TOCAGEN INC COM 888846102 2,505 375,000 SH   DFND   375,000 0 0
TOTTENHAM ACQUISITION I LTD *W EXP 05/06/202 G8959N114 41 542,000 SH   DFND   542,000 0 0
TOTTENHAM ACQUISITION I LTD RIGHT 06/05/2020 G8959N122 50 134,000 SH   DFND   134,000 0 0
TRACON PHARMACEUTICALS INC COM 89237H100 1,862 2,738,938 SH   DFND   2,738,938 0 0
TRIDENT ACQUISITIONS CORP *W EXP 05/09/202 89615T114 299 1,993,750 SH   DFND   1,993,750 0 0
TRINITY MERGER CORP *W EXP 05/11/202 89653L114 230 700,000 SH   DFND   700,000 0 0
TRIVAGO N V SPON ADS A SHS 89686D105 14,530 3,451,402 SH   DFND   3,451,402 0 0
TRUECAR INC COM 89785L107 6,027 1,104,000 SH   DFND   1,104,000 0 0
TWELVE SEAS INVESTMENT COMPA *W EXP 12/22/202 G9145A115 122 581,850 SH   DFND   581,850 0 0
TWELVE SEAS INVESTMENT COMPA RIGHT 12/22/2019 G9145A131 51 175,000 SH   DFND   175,000 0 0
UNIQURE NV SHS N90064101 39,075 500,000 SH   DFND   500,000 0 0
SELECT SECTOR SPDR TR SBI INT-UTILS 81369Y886 23,852 400,000 SH Put DFND   400,000 0 0
VECTOIQ ACQUISITION CORP *W EXP 05/11/202 92243N111 238 500,000 SH   DFND   500,000 0 0
WARRIOR MET COAL INC COM 93627C101 6,399 245,000 SH   DFND   245,000 0 0
XBIOTECH INC COM 98400H102 455 60,000 SH   DFND   60,000 0 0
XYNOMIC PHARMACUTCLS HLDNG I COM 98421X102 34 10,000 SH   DFND   10,000 0 0
XYNOMIC PHARMACUTCLS HLDNG I *W EXP 05/15/202 98421X110 11 50,000 SH   DFND   50,000 0 0
ZAFGEN INC COM 98885E103 1,588 1,335,104 SH   DFND   1,335,104 0 0
ZILLOW GROUP INC CL A 98954M101 2,288 50,000 SH   DFND   50,000 0 0
ZIOPHARM ONCOLOGY INC COM 98973P101 875 150,000 SH   DFND   150,000 0 0
ZOGENIX INC COM NEW 98978L204 2,389 50,000 SH   DFND   50,000 0 0