The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
58 COM INC SPON ADR REP A 31680Q104 73,042 1,174,879 SH   SOLE 1,174,879 0 0
ACCELERON PHARMA INC COM 00434H108 2,115 51,489 SH   SOLE 51,489 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 1,607 54,384 SH   SOLE 54,384 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 1,867 37,436 SH   SOLE 37,436 0 0
ALECTOR INC COM 014442107 2,296 120,859 SH   SOLE 120,859 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 208,825 1,232,370 SH   SOLE 1,232,370 0 0
ALLY FINL INC COM 02005N100 117,133 3,779,719 SH   SOLE 3,320,419 0 459,300
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 1,644 22,655 SH   SOLE 22,655 0 0
ALPHABET INC CAP STK CL A 02079K305 216,626 200,061 SH   SOLE 179,809 0 20,252
ALPHABET INC CAP STK CL C 02079K107 121,941 112,813 SH   SOLE 103,703 0 9,110
AMERICAN EAGLE OUTFITTERS IN COM 02553E106 41,140 2,434,299 SH   SOLE 2,111,301 0 322,998
ANALOG DEVICES INC COM 032654105 1,210 10,720 SH   SOLE 10,720 0 0
APPLE INC COM 037833100 1,520 7,680 SH   SOLE 7,680 0 0
ARCUS BIOSCIENCES INC COM 03969F109 1,162 146,193 SH   SOLE 146,193 0 0
ARLO TECHNOLOGIES INC COM 04206A101 56 14,060 SH   SOLE 14,060 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 1,275 415,450 SH   SOLE 415,450 0 0
AT HOME GROUP INC COM 04650Y100 2,766 415,383 SH   SOLE 415,383 0 0
AUTOHOME INC SP ADR RP CL A 05278C107 114,186 1,333,635 SH   SOLE 1,333,635 0 0
BAIDU INC SPON ADR REP A 056752108 7,542 64,264 SH   SOLE 64,264 0 0
BARRICK GOLD CORPORATION COM 067901108 883 56,000 SH   SOLE 56,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 1,184 13,820 SH   SOLE 13,820 0 0
BITAUTO HLDGS LTD SPONSORED ADS 091727107 1,706 162,911 SH   SOLE 162,911 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 1,202 12,746 SH   SOLE 12,746 0 0
BOOKING HLDGS INC COM 09857L108 194,329 103,658 SH   SOLE 93,806 0 9,852
BRF SA SPONSORED ADR 10552T107 10,914 1,436,005 SH   SOLE 1,206,928 0 229,077
CALLAWAY GOLF CO COM 131193104 7,105 414,060 SH   SOLE 414,060 0 0
CARNIVAL CORP UNIT 99/99/9999 143658300 1,362 29,260 SH   SOLE 29,260 0 0
CARVANA CO CL A 146869102 9,607 153,487 SH   SOLE 153,487 0 0
CELLULAR BIOMEDICINE GROUP I COM NEW 15117P102 11,123 672,885 SH   SOLE 672,885 0 0
CENTURYLINK INC COM 156700106 5,084 432,343 SH   SOLE 432,343 0 0
CF INDS HLDGS INC COM 125269100 116,502 2,494,161 SH   SOLE 2,163,055 0 331,106
CISCO SYS INC COM 17275R102 1,954 35,700 SH   SOLE 35,700 0 0
COHERUS BIOSCIENCES INC COM 19249H103 3,718 168,237 SH   SOLE 168,237 0 0
CRITEO S A SPONS ADS 226718104 354 20,551 SH   SOLE 20,551 0 0
DERMIRA INC COM 24983L104 1,112 116,325 SH   SOLE 116,325 0 0
EBAY INC COM 278642103 1,122 28,417 SH   SOLE 28,417 0 0
EQUIFAX INC COM 294429105 32,713 241,892 SH   SOLE 241,892 0 0
FACEBOOK INC CL A 30303M102 425,472 2,204,516 SH   SOLE 1,975,667 0 228,849
FIVE PRIME THERAPEUTICS INC COM 33830X104 1,153 191,237 SH   SOLE 191,237 0 0
GENERAL ELECTRIC CO COM 369604103 107,245 10,213,829 SH   SOLE 9,317,390 0 896,439
GILEAD SCIENCES INC COM 375558103 136,200 2,015,993 SH   SOLE 1,831,993 0 184,000
GOLDEN OCEAN GROUP LTD SHS NEW G39637205 165,356 3,350,000 SH   SOLE 3,350,000 0 0
HANESBRANDS INC COM 410345102 10,215 593,205 SH   SOLE 593,205 0 0
IHS MARKIT LTD SHS G47567105 30,961 485,898 SH   SOLE 485,898 0 0
INCYTE CORP COM 45337C102 2,042 24,033 SH   SOLE 24,033 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 2,048 1,137,647 SH   SOLE 1,137,647 0 0
INTEL CORP COM 458140100 264,189 5,518,881 SH   SOLE 4,942,692 0 576,189
INTELLIA THERAPEUTICS INC COM 45826J105 1,978 120,854 SH   SOLE 120,854 0 0
JD COM INC SPON ADR CL A 47215P106 1,084 35,800 SH   SOLE 35,800 0 0
JOHNSON & JOHNSON COM 478160104 1,849 13,279 SH   SOLE 13,279 0 0
LAM RESEARCH CORP COM 512807108 2,079 11,069 SH   SOLE 11,069 0 0
LIBERTY GLOBAL PLC SHS CL A G5480U104 399 14,800 SH   SOLE 14,800 0 0
LIVANOVA PLC SHS G5509L101 1,633 22,698 SH   SOLE 22,698 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 3,342 226,558 SH   SOLE 226,558 0 0
MEDICINES CO COM 584688105 1,707 46,813 SH   SOLE 46,813 0 0
MELCO RESORTS AND ENTMT LTD ADR 585464100 79,674 3,668,215 SH   SOLE 3,668,215 0 0
MERCK & CO INC COM 58933Y105 1,852 22,093 SH   SOLE 22,093 0 0
MERUS N V COM N5749R100 2,591 176,835 SH   SOLE 176,835 0 0
MICROCHIP TECHNOLOGY INC COM 595017104 178,806 2,062,349 SH   SOLE 1,832,168 0 230,181
MICRON TECHNOLOGY INC COM 595112103 193,765 5,021,110 SH   SOLE 4,397,047 0 624,063
MICROSOFT CORP COM 594918104 3,461 25,835 SH   SOLE 25,835 0 0
MODERNA INC COM 60770K107 21,704 1,482,545 SH   SOLE 1,310,687 0 171,858
MOMO INC ADR 60879B107 95,834 2,676,938 SH   SOLE 2,676,938 0 0
MYOVANT SCIENCES LTD COM G637AM102 2,158 238,398 SH   SOLE 238,398 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 4,192 138,115 SH   SOLE 138,115 0 0
NETGEAR INC COM 64111Q104 180 7,100 SH   SOLE 7,100 0 0
NIELSEN HLDGS PLC SHS EUR G6518L108 5,435 240,481 SH   SOLE 240,481 0 0
ORACLE CORP COM 68389X105 1,676 29,418 SH   SOLE 29,418 0 0
OWENS CORNING NEW COM 690742101 91,906 1,579,148 SH   SOLE 1,434,045 0 145,103
PAYPAL HLDGS INC COM 70450Y103 1,881 16,437 SH   SOLE 16,437 0 0
PEABODY ENERGY CORP NEW COM 704551100 58,662 2,434,111 SH   SOLE 2,236,019 0 198,092
PERKINELMER INC COM 714046109 3,177 32,975 SH   SOLE 32,975 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 1,872 398,228 SH   SOLE 398,228 0 0
PROTHENA CORP PLC SHS G72800108 2,008 189,991 SH   SOLE 189,991 0 0
QIAGEN NV SHS NEW N72482123 1,682 47,117 SH   SOLE 47,117 0 0
QIWI PLC SPON ADR REP B 74735M108 18,985 970,122 SH   SOLE 970,122 0 0
QUANTERIX CORP COM 74766Q101 4,772 141,220 SH   SOLE 141,220 0 0
ROKU INC COM CL A 77543R102 915 10,101 SH   SOLE 10,101 0 0
SANGAMO THERAPEUTICS INC COM 800677106 1,816 168,585 SH   SOLE 168,585 0 0
SEATTLE GENETICS INC COM 812578102 1,153 16,660 SH   SOLE 16,660 0 0
SINA CORP ORD G81477104 36,468 845,530 SH   SOLE 845,530 0 0
SKYWORKS SOLUTIONS INC COM 83088M102 197,303 2,553,417 SH   SOLE 2,277,558 0 275,859
STAMPS COM INC COM NEW 852857200 118 2,600 SH   SOLE 2,600 0 0
STARS GROUP INC COM 85570W100 11,718 686,487 SH   SOLE 686,487 0 0
STOKE THERAPEUTICS INC COM 86150R107 29 1,000 SH   SOLE 1,000 0 0
TECHNIPFMC PLC COM G87110105 235,292 9,070,608 SH   SOLE 7,917,308 0 1,153,300
TRANSOCEAN LTD REG SHS H8817H100 116,686 18,203,700 SH   SOLE 16,220,961 0 1,982,739
TWILIO INC CL A 90138F102 577 4,229 SH   SOLE 4,229 0 0
UNUM THERAPEUTICS INC COM 903214104 447 170,700 SH   SOLE 170,700 0 0
WABTEC CORP COM 929740108 3,936 54,855 SH   SOLE 50,041 0 4,814
WARRIOR MET COAL INC COM 93627C101 21,225 812,600 SH   SOLE 679,300 0 133,300
WAVE LIFE SCIENCES LTD SHS Y95308105 1,851 70,942 SH   SOLE 70,942 0 0
WEIBO CORP SPONSORED ADR 948596101 134,863 3,096,729 SH   SOLE 2,660,023 0 436,706
XILINX INC COM 983919101 1,086 9,209 SH   SOLE 9,209 0 0
YUM CHINA HLDGS INC COM 98850P109 38,087 824,389 SH   SOLE 824,389 0 0
ZAI LAB LTD ADR 98887Q104 4,224 121,122 SH   SOLE 121,122 0 0
ZTO EXPRESS CAYMAN INC SPONSORED ADS A 98980A105 191,987 10,041,186 SH   SOLE 8,900,781 0 1,140,405