The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 97,565 2,375,000 SH   OTR   2,375,000 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 1,208 25,000 SH   OTR   25,000 0 0
AKERO THERAPEUTICS INC COM 00973Y108 2,873 150,000 SH   OTR   150,000 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 84,725 500,000 SH   OTR   500,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 79,816 1,100,000 SH   OTR   1,100,000 0 0
ALPHABET INC CAP STK CL C 02079K107 153,730 142,223 SH   OTR   142,223 0 0
ALTABA INC COM 021346101 1,967,494 28,362,317 SH   OTR   28,362,317 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 82,408 4,250,000 SH   OTR   4,250,000 0 0
ANADARKO PETE CORP COM 032511107 738,410 10,465,000 SH   OTR   10,465,000 0 0
ANTHEM INC COM 036752103 296,321 1,050,000 SH   OTR   1,050,000 0 0
APTINYX INC COM 03836N103 2,238 670,000 SH   OTR   670,000 0 0
ARRAY BIOPHARMA INC COM 04269X105 393,805 8,500,000 SH   OTR   8,500,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 53,000 2,000,000 SH   OTR   2,000,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 177,331 1,540,000 SH   OTR   1,540,000 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 1,349 100,000 SH   OTR   100,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 169,248 4,100,000 SH   OTR   4,100,000 0 0
AVROBIO INC COM 05455M100 16,848 1,036,147 SH   OTR   1,036,147 0 0
BOOKING HLDGS INC COM 09857L108 182,689 97,449 SH   OTR   97,449 0 0
CARA THERAPEUTICS INC COM 140755109 20,454 951,326 SH   OTR   951,326 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 276,786 700,405 SH   OTR   700,405 0 0
CHEMOCENTRYX INC COM 16383L106 18,600 2,000,000 SH   OTR   2,000,000 0 0
CIGNA CORP NEW COM 125523100 165,428 1,050,000 SH   OTR   1,050,000 0 0
CITRIX SYS INC COM 177376100 188,041 1,916,051 SH   OTR   1,916,051 0 0
CLOVIS ONCOLOGY INC NOTE 1.250% 5/0 189464AC4 11,684 18,750,000 PRN   OTR   18,750,000 0 0
CODEXIS INC COM 192005106 23,038 1,250,000 SH   OTR   1,250,000 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 23,550 500,000 SH   OTR   500,000 0 0
CVS HEALTH CORP COM 126650100 44,818 822,500 SH   OTR   822,500 0 0
CYCLERION THERAPEUTICS INC COM 23255M105 6,230 544,085 SH   OTR   544,085 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 10,600 1,000,000 SH   OTR   1,000,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 81,005 960,000 SH   OTR   960,000 0 0
EQUIFAX INC COM 294429105 197,961 1,463,779 SH   OTR   1,463,779 0 0
EQUINIX INC COM 29444U700 193,210 383,132 SH   OTR   383,132 0 0
EXELIXIS INC COM 30161Q104 64,110 3,000,000 SH   OTR   3,000,000 0 0
FACEBOOK INC CL A 30303M102 174,527 904,284 SH   OTR   904,284 0 0
FATE THERAPEUTICS INC COM 31189P102 50,750 2,500,000 SH   OTR   2,500,000 0 0
FIBROGEN INC COM 31572Q808 76,806 1,700,000 SH   OTR   1,700,000 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 348,735 2,842,640 SH   OTR   2,842,640 0 0
FIRST DATA CORP NEW COM CL A 32008D106 38,575 1,425,000 SH   OTR   1,425,000 0 0
FOX CORP CL A COM 35137L105 30,646 836,400 SH   OTR   836,400 0 0
FOX CORP CL B COM 35137L204 43,197 1,182,500 SH   OTR   1,182,500 0 0
GENERAL DYNAMICS CORP COM 369550108 242,769 1,335,214 SH   OTR   1,335,214 0 0
GENESEE & WYO INC CL A 371559105 77,500 775,000 SH   OTR   775,000 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 59,175 1,125,000 SH   OTR   1,125,000 0 0
GOSSAMER BIO INC COM 38341P102 2,218 100,000 SH   OTR   100,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 64,990 3,080,083 SH   OTR 1 3,080,083 0 0
IHS MARKIT LTD SHS G47567105 229,710 3,604,997 SH   OTR   3,604,997 0 0
INVITAE CORP COM 46185L103 21,150 900,000 SH   OTR   900,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 140,377 5,725,000 SH   OTR   5,725,000 0 0
IQVIA HLDGS INC COM 46266C105 414,963 2,579,011 SH   OTR   2,579,011 0 0
LIBERTY GLOBAL PLC SHS CL A G5480U104 56,247 2,083,977 SH   OTR   2,083,977 0 0
LIBERTY GLOBAL PLC SHS CL C G5480U120 97,524 3,675,974 SH   OTR   3,675,974 0 0
MICROSOFT CORP COM 594918104 168,455 1,257,503 SH   OTR   1,257,503 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107 6,788 250,000 SH   OTR   250,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 102,485 995,000 SH   OTR   995,000 0 0
MYOKARDIA INC COM 62857M105 100,280 2,000,000 SH   OTR   2,000,000 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 10,623 350,000 SH   OTR   350,000 0 0
NOVOCURE LTD ORD SHS G6674U108 75,876 1,200,000 SH   OTR   1,200,000 0 0
NXP SEMICONDUCTORS N V COM N6596X109 41,972 430,000 SH   OTR   430,000 0 0
OCCIDENTAL PETE CORP COM 674599105 1,006 20,000 SH   OTR   20,000 0 0
PERSONALIS INC COM 71535D106 5,021 184,932 SH   OTR   184,932 0 0
PFENEX INC COM 717071104 4,044 600,000 SH   OTR   600,000 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 9,931 756,961 SH   OTR   756,961 0 0
PLAYA HOTELS & RESORTS NV SHS N70544106 235,979 30,606,930 SH   OTR   30,606,930 0 0
PROGENICS PHARMACEUTICALS IN COM 743187106 34,203 5,543,386 SH   OTR   5,543,386 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 18,165 1,500,000 SH   OTR   1,500,000 0 0
PTC THERAPEUTICS INC COM 69366J200 27,000 600,000 SH   OTR   600,000 0 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 26,705 24,130,000 PRN   OTR   24,130,000 0 0
QUOTIENT LTD SHS G73268107 23,375 2,500,000 SH   OTR   2,500,000 0 0
RADIUS HEALTH INC COM NEW 750469207 49,771 2,043,149 SH   OTR   2,043,149 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 1,132 1,250,000 PRN   OTR   1,250,000 0 0
READY CAP CORP COM 75574U101 33,424 2,243,239 SH   OTR   2,243,239 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 75,480 800,000 SH   OTR   800,000 0 0
S&P GLOBAL INC COM 78409V104 191,523 840,786 SH   OTR   840,786 0 0
SAGE THERAPEUTICS INC COM 78667J108 91,545 500,000 SH   OTR   500,000 0 0
SANOFI RIGHT 12/31/2020 80105N113 3,550 6,827,805 SH   OTR   6,827,805 0 0
SAREPTA THERAPEUTICS INC COM 803607100 75,975 500,000 SH   OTR   500,000 0 0
SAVARA INC COM 805111101 8,236 3,475,000 SH   OTR   3,475,000 0 0
SEA LTD SPONSORED ADS 81141R100 112,118 3,375,000 SH   OTR   3,375,000 0 0
SHERWIN WILLIAMS CO COM 824348106 213,425 465,699 SH   OTR   465,699 0 0
SINA CORP ORD G81477104 21,996 510,000 SH   OTR   510,000 0 0
SOLARCITY CORP NOTE 1.625%11/0 83416TAC4 5,304 5,500,000 PRN   OTR   5,500,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 1,068,718 3,647,500 SH Put OTR   3,647,500 0 0
SPRINT CORPORATION COM 85207U105 70,135 10,675,000 SH   OTR   10,675,000 0 0
STEMLINE THERAPEUTICS INC COM 85858C107 22,980 1,500,000 SH   OTR   1,500,000 0 0
T MOBILE US INC COM 872590104 31,567 425,780 SH   OTR   425,780 0 0
TRANSUNION COM 89400J107 122,934 1,672,343 SH   OTR   1,672,343 0 0
TWIST BIOSCIENCE CORP COM 90184D100 8,908 307,055 SH   OTR   307,055 0 0
UNIQURE NV SHS N90064101 7,815 100,000 SH   OTR   100,000 0 0
VERACYTE INC COM 92337F107 9,979 350,000 SH   OTR   350,000 0 0
VISA INC COM CL A 92826C839 206,139 1,187,779 SH   OTR   1,187,779 0 0
VOYA FINL INC COM 929089100 10,231 185,000 SH   OTR   185,000 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 20,415 750,000 SH   OTR   750,000 0 0
WABTEC CORP COM 929740108 471,346 6,568,373 SH   OTR   6,568,373 0 0
ZAFGEN INC COM 98885E103 2,142 1,800,000 SH   OTR   1,800,000 0 0
ZAYO GROUP HLDGS INC COM 98919V105 92,806 2,820,000 SH   OTR   2,820,000 0 0
ZEALAND PHARMA A S SPONSORED ADR 98920Y304 21,550 1,000,000 SH   OTR   1,000,000 0 0
ZOGENIX INC COM NEW 98978L204 95,560 2,000,000 SH   OTR   2,000,000 0 0
ZYMEWORKS INC COM 98985W102 38,642 1,756,470 SH   OTR   1,756,470 0 0