The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
21VIANET GROUP INC SPONSORED ADS A 90138A103 83,961 10,778,004 SH   DFND 8,23 10,778,004 0 0
AC IMMUNE SA SHS H00263105 14,508 2,614,095 SH   DFND 12,22,27 2,614,095 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 4,418,438 26,075,175 SH   DFND 2,6,19,20,21 26,075,175 0 0
ALTERYX INC COM CL A 02156B103 1,617 14,821 SH   DFND 11,13 14,821 0 0
AMAZON COM INC COM 023135106 66,567 35,153 SH   DFND 2,19,21 35,153 0 0
AMYRIS INC COM NEW 03236M200 9,635 2,706,336 SH   DFND 4,12,16 2,706,336 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 4,367 1,422,475 SH   DFND 12,22,27 1,422,475 0 0
BEIGENE LTD SPONSORED ADR 07725L102 281,379 2,270,100 SH   DFND 12,22,27 2,270,100 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 203,223 2,372,712 SH   DFND 4,12,16,22,27 2,372,712 0 0
BP PLC SPONSORED ADR 055622104 37,549 900,457 SH   DFND 9,21 900,457 0 0
CENTURYLINK INC COM 156700106 1,143,771 97,259,407 SH   DFND 2,3,7,10,19,21,23 97,259,407 0 0
CHINA BIOLOGIC PRODS HLDGS I COM G21515104 94,347 990,000 SH   DFND 12,22,27 990,000 0 0
COGNEX CORP COM 192422103 6,678 139,192 SH   DFND 2,19,21 139,192 0 0
COHERUS BIOSCIENCES INC COM 19249H103 144,890 6,556,116 SH   DFND 12,22,27 6,556,116 0 0
CORTEVA INC COM 22052L104 55,395 1,873,363 SH   DFND 9,21 1,873,363 0 0
DELL TECHNOLOGIES INC CL C 24703L202 923,636 18,181,818 SH   DFND 17,23,26 18,181,818 0 0
DENALI THERAPEUTICS INC COM 24823R105 91,561 4,410,457 SH   DFND 12,22,25,27 4,410,457 0 0
DOW INC COM 260557103 92,376 1,873,363 SH   DFND 9,21 1,873,363 0 0
DUPONT DE NEMOURS INC COM 26614N102 140,633 1,873,363 SH   DFND 9,21 1,873,363 0 0
EROS INTL PLC SHS NEW G3788M114 3,720 2,755,310 SH   DFND 6,19,21 2,755,310 0 0
EVOQUA WATER TECHNOLOGIES CO COM 30057T105 85,977 6,037,705 SH   DFND 11,13 6,037,705 0 0
FARFETCH LTD ORD SH CL A 30744W107 59,058 2,839,308 SH   DFND 18,19,21 2,839,308 0 0
FTS INTERNATIONAL INC COM 30283W104 232,224 41,617,144 SH   DFND 11,15 41,617,144 0 0
GLOBAL PMTS INC COM 37940X102 140,302 876,176 SH   DFND 12,14 876,176 0 0
GRACE W R & CO DEL NEW COM 38388F108 166,491 2,187,501 SH   DFND 9,21 2,187,501 0 0
GUARDANT HEALTH INC COM 40131M109 139,251 1,613,007 SH   DFND 12,22,25 1,613,007 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 131,505 1,011,265 SH   DFND 9,21 1,011,265 0 0
HOMOLOGY MEDICINES INC COM 438083107 63,021 3,220,293 SH   DFND 12,22,25,27 3,220,293 0 0
ICICI BK LTD ADR 45104G104 108,775 8,639,819 SH   DFND 4,9,12,21 8,639,819 0 0
IHS MARKIT LTD SHS G47567105 722,315 11,335,769 SH   DFND 8,23 11,335,769 0 0
ILLUMINA INC COM 452327109 20,415 55,452 SH   DFND 2,19,21 55,452 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 12,941 790,527 SH   DFND 9,12,21,22,25 790,527 0 0
KKR REAL ESTATE FIN TR INC COM 48251K100 48,585 2,439,024 SH   DFND 2,19,21 2,439,024 0 0
MASTERCARD INC CL A 57636Q104 381,112 1,440,714 SH   DFND 2,12,14,19,21 1,440,714 0 0
NIO INC SPON ADS 62914V106 105,690 41,446,985 SH   DFND 1,23,24 41,446,985 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 13,990 1,000,000 SH   DFND 12,22,27 1,000,000 0 0
PAYPAL HLDGS INC COM 70450Y103 719,556 6,286,524 SH   DFND 6,12,14,19,21 6,286,524 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 140,375 5,174,168 SH   DFND 2,4,12,16,19,21,22,27 5,174,168 0 0
PPG INDS INC COM 693506107 201,633 1,727,645 SH   DFND 2,19,21 1,727,645 0 0
ROCKWELL AUTOMATION INC COM 773903109 7,276 44,409 SH   DFND 2,19,21 44,409 0 0
ROYAL DUTCH SHELL PLC SPON ADR B 780259107 238,967 3,635,028 SH   DFND 9,21 3,635,028 0 0
SLACK TECHNOLOGIES INC COM CL A 83088V102 412 10,984 SH   DFND 11,13 10,984 0 0
STONECO LTD COM CL A G85158106 16,831 569,000 SH   DFND 2,19,21 569,000 0 0
SVMK INC COM 78489X103 2,767 167,620 SH   DFND 11 167,620 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 441,427 1,503,087 SH   DFND 4,12,16 1,503,087 0 0
TOTAL S A SPONSORED ADS 89151E109 25,713 460,885 SH   DFND 9,21 460,885 0 0
TRADEWEB MKTS INC CL A 892672106 54,763 1,250,000 SH   DFND 2,19,21 1,250,000 0 0
TUNIU CORP SPONSORED ADS A 89977P106 26,468 8,194,444 SH   DFND 8,23 8,194,444 0 0
UNIVAR INC COM 91336L107 225,220 10,218,695 SH   DFND 5,23,24 10,218,695 0 0
VIRTU FINL INC CL A 928254101 367,657 16,880,503 SH   DFND 2,11,13,19,21 16,880,503 0 0
VISA INC COM CL A 92826C839 746,437 4,300,992 SH   DFND 2,12,14,19,21 4,300,992 0 0
WORLDPAY INC CL A 981558109 297,329 2,426,186 SH   DFND 2,12,14,19,21 2,426,186 0 0
ZTO EXPRESS CAYMAN INC SPONSORED ADS A 98980A105 232,819 12,176,750 SH   DFND 2,19,21 12,176,750 0 0