The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abbott Laboratories COM 002824100 21,828 259,552 SH   SOLE   0 0 259,552
Abeona Therapeutics Inc Reg COM 00289Y107 3,103 649,123 SH   SOLE   0 0 649,123
Abiomed Inc COM 003654100 24,200 92,900 SH   SOLE   0 0 92,900
Acceleron Pharma Inc Reg COM 00434H108 2,876 70,000 SH   SOLE   0 0 70,000
Achillion Pharmaceuticals Inc COM 00448Q201 745 277,800 SH   SOLE   0 0 277,800
Adverum Biotechnologies Inc COM 00773U108 1,423 119,673 SH   SOLE   0 0 119,673
Aerie Pharmaceuticals Inc COM 00771V108 7,683 260,000 SH   SOLE   0 0 260,000
Agios Pharmaceuticals Inc COM 00847X104 9,976 200,000 SH   SOLE   0 0 200,000
Aimmune Therapeutics Inc Reg COM 00900T107 3,106 149,201 SH   SOLE   0 0 149,201
Alexion Pharmaceuticals Inc COM 015351109 26,591 203,017 SH   SOLE   0 0 203,017
Alkermes Plc SHS G01767105 2,714 120,399 SH   SOLE   0 0 120,399
Alnylam Pharmaceuticals Inc COM 02043Q107 5,917 81,550 SH   SOLE   0 0 81,550
Amarin Corp Plc spons ADR repr 1 Share SPONS ADR NEW 023111206 6,802 350,800 SH   SOLE   0 0 350,800
AmerisourceBergen Corp COM 03073E105 12,066 141,520 SH   SOLE   0 0 141,520
Anheuser-Busch InBev SA ADR spons repr 1 Share SPONSORED ADR 03524A108 302 3,409 SH   SOLE   0 0 3,409
Anthem Inc COM 036752103 25,399 90,000 SH   SOLE   0 0 90,000
Arena Pharmaceuticals Inc Reg COM 040047607 9,967 170,000 SH   SOLE   0 0 170,000
Becton Dickinson & Co COM 075887109 20,161 80,000 SH   SOLE   0 0 80,000
BioMarin Pharmaceutical Inc COM 09061G101 24,098 281,349 SH   SOLE   0 0 281,349
Bluebird Bio Inc COM 09609G100 8,904 70,000 SH   SOLE   0 0 70,000
Boston Scientific Corp COM 101137107 16,672 387,908 SH   SOLE   0 0 387,908
Bristol Myers Squibb Co COM 110122108 15,346 338,386 SH   SOLE   0 0 338,386
Centene Corp COM 15135B101 15,470 295,000 SH   SOLE   0 0 295,000
Chevron Corp COM 166764100 370 2,974 SH   SOLE   0 0 2,974
Cigna Corp Reg COM 125523100 15,155 96,191 SH   SOLE   0 0 96,191
Coherus BioSciences Inc COM 19249H103 8,619 390,000 SH   SOLE   0 0 390,000
CVS Health Corp COM 126650100 18,732 343,768 SH   SOLE   0 0 343,768
Dermira Inc Reg COM 24983L104 4,783 500,329 SH   SOLE   0 0 500,329
Diplomat Pharmacy Inc Reg COM 25456K101 7,329 1,203,405 SH   SOLE   0 0 1,203,405
Dynavax Technologies Corp COM NEW 268158201 4,925 1,234,335 SH   SOLE   0 0 1,234,335
Edwards Lifesciences Corp COM 28176E108 5,835 31,585 SH   SOLE   0 0 31,585
Eli Lilly & Co COM 532457108 17,726 160,000 SH   SOLE   0 0 160,000
Epizyme Inc Reg COM 29428V104 6,196 493,679 SH   SOLE   0 0 493,679
Esperion Therapeutics Inc COM 29664W105 19,171 412,093 SH   SOLE   0 0 412,093
Exact Sciences Corp Reg COM 30063P105 10,624 90,000 SH   SOLE   0 0 90,000
Exelixis Inc COM 30161Q104 9,830 460,000 SH   SOLE   0 0 460,000
Exxon Mobil Corp COM 30231G102 295 3,854 SH   SOLE   0 0 3,854
FibroGen Inc COM 31572Q808 15,697 347,439 SH   SOLE   0 0 347,439
Ford Motor Co COM 345370860 298 29,164 SH   SOLE   0 0 29,164
G1 Therapeutics Inc Reg COM 3621LQ109 8,409 274,274 SH   SOLE   0 0 274,274
Glaukos Corp COM 377322102 17,788 235,911 SH   SOLE   0 0 235,911
HCA Healthcare Inc COM 40412C101 18,405 136,164 SH   SOLE   0 0 136,164
HMS Holdings Corp Reg COM 40425J101 3,239 100,000 SH   SOLE   0 0 100,000
Horizon Therapeutics Plc COM 440407104 26,169 1,087,656 SH   SOLE   0 0 1,087,656
Humana Inc COM 444859102 27,857 105,000 SH   SOLE   0 0 105,000
IBM Corp COM 459200101 305 2,215 SH   SOLE   0 0 2,215
Immunomedics Inc COM 452907108 11,808 851,367 SH   SOLE   0 0 851,367
Incyte Corp Ltd COM 45337C102 8,496 100,000 SH   SOLE   0 0 100,000
Intercept Pharmaceuticals Inc COM 45845P108 2,992 37,600 SH   SOLE   0 0 37,600
Intra-Cellular Therapies Inc COM 46116X101 12,329 949,833 SH   SOLE   0 0 949,833
Iovance Biotherapeutics Inc Reg COM 462260100 18,407 750,700 SH   SOLE   0 0 750,700
Janus Henderson Group Plc Reg ORD SHS G4474Y214 228 10,645 SH   SOLE   0 0 10,645
Jazz Pharmaceuticals Plc SHS USD G50871105 26,683 187,171 SH   SOLE   0 0 187,171
JPMorgan Chase & Co COM 46625H100 276 2,472 SH   SOLE   0 0 2,472
Livanova Plc SHS G5509L101 10,794 150,000 SH   SOLE   0 0 150,000
Macrogenics Inc COM 556099109 14,546 857,169 SH   SOLE   0 0 857,169
Madrigal Pharmaceuticals Inc Reg COM 558868105 3,902 37,225 SH   SOLE   0 0 37,225
Medicines Co COM 584688105 7,294 200,000 SH   SOLE   0 0 200,000
Medtronic Plc Reg SHS G5960L103 15,863 162,883 SH   SOLE   0 0 162,883
Microsoft Corp COM 594918104 205 1,532 SH   SOLE   0 0 1,532
Mirati Therapeutics Inc Reg COM 60468T105 18,747 182,008 SH   SOLE   0 0 182,008
MyoKardia Inc Reg COM 62857M105 11,283 225,024 SH   SOLE   0 0 225,024
NanoString Technologies Inc Reg COM 63009R109 3,642 120,000 SH   SOLE   0 0 120,000
Nektar Therapeutics COM 640268108 25,796 725,000 SH   SOLE   0 0 725,000
Neurocrine Biosciences Inc COM 64125C109 15,197 180,000 SH   SOLE   0 0 180,000
NovoCure Ltd Reg ORD SHS G6674U108 23,136 365,899 SH   SOLE   0 0 365,899
Omnicell Inc COM 68213N109 8,635 100,375 SH   SOLE   0 0 100,375
Pieris Pharmaceuticals Inc Reg COM 720795103 1,410 300,000 SH   SOLE   0 0 300,000
Qiagen NV Reg SHS NEW N72482123 2,438 60,000 SH   SOLE   0 0 60,000
Qualcomm Inc COM 747525103 258 3,391 SH   SOLE   0 0 3,391
Ra Pharmaceuticals Inc Reg COM 74933V108 6,886 229,000 SH   SOLE   0 0 229,000
Regeneron Pharmaceuticals Inc COM 75886F107 14,089 45,014 SH   SOLE   0 0 45,014
Revance Therapeutics Inc COM 761330109 2,506 193,181 SH   SOLE   0 0 193,181
Rigel Pharmaceuticals Inc COM NEW 766559603 5,911 2,264,942 SH   SOLE   0 0 2,264,942
Sage Therapeutics Inc COM 78667J108 3,962 21,639 SH   SOLE   0 0 21,639
Sangamo Therapeutics Inc Reg COM 800677106 8,551 793,957 SH   SOLE   0 0 793,957
Seattle Genetics Inc Reg COM 812578102 9,369 135,374 SH   SOLE   0 0 135,374
Spark Therapeutics Inc COM 84652J103 1,024 10,000 SH   SOLE   0 0 10,000
Stemline Therapeutics Inc Reg COM 85858C107 7,568 493,999 SH   SOLE   0 0 493,999
Sunesis Pharmaceuticals Inc Reg COM PAR 867328700 274 377,244 SH   SOLE   0 0 377,244
The Walt Disney Co COM DISNEY 254687106 291 2,083 SH   SOLE   0 0 2,083
Thermo Fisher Scientific Inc COM 883556102 8,752 29,800 SH   SOLE   0 0 29,800
United Health Group Inc COM 91324P102 25,621 105,000 SH   SOLE   0 0 105,000
Wells Fargo & Co COM 949746101 249 5,272 SH   SOLE   0 0 5,272
Vertex Pharmaceuticals Inc COM 92532F100 33,968 185,232 SH   SOLE   0 0 185,232
ViewRay Inc Reg COM 92672L107 5,850 664,023 SH   SOLE   0 0 664,023
Viking Therapeutics Inc Reg COM 92686J106 2,419 291,499 SH   SOLE   0 0 291,499
Xencor Inc COM 98401F105 13,089 319,792 SH   SOLE   0 0 319,792