The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2U INC COM USD0.001 COM 90214J101 144,933 2,045,635 SH   DFND   0 0 2,045,635
ABIOMED INC COM USD0.01 COM 003654100 62,420 218,564 SH   DFND   0 0 218,564
ACACIA COMMUNICATIONS INC COM COM 00401C108 997 17,385 SH   DFND   0 0 17,385
ACTIVISION BLIZZARD INC COM USD0.000001 COM 00507V109 3,976 87,329 SH   DFND   0 0 87,329
ADESTO TECHNOLOGIES CORP COM COM 00687D101 9,487 1,568,132 SH   DFND   0 0 1,568,132
ADOBE INC COM COM 00724F101 45,076 169,148 SH   DFND   0 0 169,148
ADVANCED MICRO DEVICES INC COM COM 007903107 526 20,595 SH   DFND   0 0 20,595
ADYEN NV 144A COM N3501V104 84,527 107,850 SH   DFND   0 0 107,850
AEROJET ROCKETDYNE HLDGS INC COM COM 007800105 20,446 575,460 SH   DFND   0 0 575,460
ALASKA COMM SYS GRP INC COM 01167P101 3,722 1,938,300 SH   DFND   0 0 1,938,300
ALDEYRA THERAPEUTICS USD0.001 COM 01438T106 1,974 218,636 SH   DFND   0 0 218,636
ALECTOR INC COM COM 014442107 4,088 218,385 SH   DFND   0 0 218,385
ALIBABA GROUP HOLDING LTD SPON ADS EACH REP ONE ORD SHS COM 01609W102 74,343 407,469 SH   DFND   0 0 407,469
ALLAKOS INC COM COM 01671P100 1,313 32,417 SH   DFND   0 0 32,417
ALLEGIANT TRAVEL COMPANY COM USD0.001 COM 01748X102 12,243 94,561 SH   DFND   0 0 94,561
ALLOGENE THERAPEUTICS INC COM COM 019770106 63 2,182 SH   DFND   0 0 2,182
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 92,307 987,770 SH   DFND   0 0 987,770
ALPHABET INC CAP STK CL A COM 02079K305 53,639 45,577 SH   DFND   0 0 45,577
ALPHABET INC CAP STK CL C COM 02079K107 60,142 51,258 SH   DFND   0 0 51,258
ALTIUS MINERALS CORP COM ISIN #CA0209361009 SEDOL #2122355 COM 020936100 7,022 732,928 SH   DFND   0 0 732,928
ALTUS MIDSTREAM CO CL A COM 02215L100 3,221 545,938 SH   DFND   0 0 545,938
AMAZON.COM INC COM 023135106 443,595 249,106 SH   DFND   0 0 249,106
AMBER ROAD INC COM USD0.001 COM 02318Y108 625 72,030 SH   DFND   0 0 72,030
AMERICAN EAGLE OUTFITTERS INC COM COM 02553E106 65,214 2,941,559 SH   DFND   0 0 2,941,559
AMERICAN TOWER CORP COM USD0.01 COM 03027X100 16,414 83,294 SH   DFND   0 0 83,294
AMYRIS INC COM NEW COM 03236M200 113 54,044 SH   DFND   0 0 54,044
ANAPLAN INC COM COM 03272L108 191 4,849 SH   DFND   0 0 4,849
APACHE CORP COM USD0.0001 CL A COM 037411105 7,188 207,381 SH   DFND   0 0 207,381
APPFOLIO INC COM CL A COM 03783C100 147 1,852 SH   DFND   0 0 1,852
APPIAN CORP CL A COM 03782L101 5,535 160,771 SH   DFND   0 0 160,771
APPLE INC COM USD0.00001 COM 037833100 5,279 27,792 SH   DFND   0 0 27,792
APPLIED OPTOELECTRONICS INC COM COM 03823U102 93 7,637 SH   DFND   0 0 7,637
AQUANTIA CORP COM COM 03842Q108 13,890 1,533,167 SH   DFND   0 0 1,533,167
ARCO PLATFORM LTD COM USD0.00005 CL A COM G04553106 11,167 345,835 SH   DFND   0 0 345,835
ARISTA NETWORKS INC COM USD0.0001 COM 040413106 134,392 427,373 SH   DFND   0 0 427,373
ARRAY BIOPHARMA INC COM 04269X105 29,776 1,221,310 SH   DFND   0 0 1,221,310
ASV HLDGS INC COM COM 00215L104 2,117 769,914 SH   DFND   0 0 769,914
AT HOME GROUP INC COM COM 04650Y100 8,268 462,943 SH   DFND   0 0 462,943
ATLASSIAN CORPORATION PLC COM USD0.1 CL A COM G06242104 21,542 191,676 SH   DFND   0 0 191,676
AUDENTES THERAPEUTICS INC COM COM 05070R104 63,206 1,619,831 SH   DFND   0 0 1,619,831
AUTO TRADER GROUP PLC ORD GBP0.01 144A REG S ISIN #GB00BVYVFW23 COM G06708104 6,008 883,905 SH   DFND   0 0 883,905
AUTODESK INC COM COM 052769106 122,854 788,435 SH   DFND   0 0 788,435
AVEDRO INC COM COM 05355N109 209 17,058 SH   DFND   0 0 17,058
AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL # COM 05462W109 843 15,085 SH   DFND   0 0 15,085
AXOGEN INC COM COM 05463X106 9,305 441,851 SH   DFND   0 0 441,851
AZUL SA SPON ADR EACH REP 3 PFD SHS COM 05501U106 104,364 3,572,880 SH   DFND   0 0 3,572,880
AZURRX BIOPHARMA INC COM COM 05502L105 1,311 541,536 SH   DFND   0 0 541,536
BANDWIDTH INC COM CL A COM 05988J103 36,939 551,652 SH   DFND   0 0 551,652
BARCLAYS BANK PLC IPATH B SHRT TERM COM 06746P621 4,234 144,691 SH   DFND   0 0 144,691
BERKLEY W R CORP COM COM 084423102 5,073 59,876 SH   DFND   0 0 59,876
BERKSHIRE HATHAWAY INC COM USD0.0033 CLASS B COM 084670702 271 1,351 SH   DFND   0 0 1,351
BIOSCRIP INC COM 09069N108 27,224 13,611,958 SH   DFND   0 0 13,611,958
BLACK KNIGHT INC COM COM 09215C105 5,231 95,975 SH   DFND   0 0 95,975
BLUEBIRD BIO INC COM COM 09609G100 6,125 38,929 SH   DFND   0 0 38,929
BOSTON SCIENTIFIC CORP COM 101137107 1,607 41,861 SH   DFND   0 0 41,861
BRIGHTCOVE INC COM USD0.001 COM 10921T101 251 29,834 SH   DFND   0 0 29,834
CALIX INC COM COM 13100M509 981 127,409 SH   DFND   0 0 127,409
CALYXT INC COM COM 13173L107 172 9,783 SH   DFND   0 0 9,783
CAREDX INC COM COM 14167L103 3,769 119,565 SH   DFND   0 0 119,565
CARL ZEISS MEDITEC AG NPV ISIN #DE0005313704 SEDOL #5922961 COM D14895102 1,446 17,359 SH   DFND   0 0 17,359
CARROLS RESTAURANT GROUP INC COM COM 14574X104 3,869 388,058 SH   DFND   0 0 388,058
CARVANA CO CL A COM 146869102 25,741 443,358 SH   DFND   0 0 443,358
CASA SYS INC COM COM 14713L102 387 46,577 SH   DFND   0 0 46,577
CATAPULT GROUP INTERNATIONAL ISIN #AU000000CAT9 SEDOL #BTL0Y76 COM Q2159P101 141 211,309 SH   DFND   0 0 211,309
CHARLOTTES WEB HOLDINGS INC COM NPV COM 16106R109 1,444 72,376 SH   DFND   0 0 72,376
CHART INDUSTRIES INC COM USD0.01 COM 16115Q308 11,780 130,142 SH   DFND   0 0 130,142
CHEGG INC COM USD0.001 COM 163092109 187,739 4,924,952 SH   DFND   0 0 4,924,952
CHIPOTLE MEXICAN GRILL INC COM COM 169656105 31 43 SH   DFND   0 0 43
CODEXIS INC COM USD0.0001 COM 192005106 51,107 2,489,389 SH   DFND   0 0 2,489,389
CONSTRUCTION PARTNERS INC COM CL A COM 21044C107 729 57,055 SH   DFND   0 0 57,055
COUPA SOFTWARE INC COM COM 22266L106 24,872 273,376 SH   DFND   0 0 273,376
COVANTA HLDG CORP COM COM 22282E102 8,102 468,071 SH   DFND   0 0 468,071
CRIMSON WINE GROUP COM USD0.01 COM 22662X100 658 79,997 SH   DFND   0 0 79,997
DEERE & COMPANY COM 244199105 16 100 SH   DFND   0 0 100
DENALI THERAPEUTICS INC COM COM 24823R105 14 596 SH   DFND   0 0 596
DEXCOM INC COM 252131107 80,960 679,765 SH   DFND   0 0 679,765
DIGI INTL INC COM COM 253798102 5,926 467,720 SH   DFND   0 0 467,720
DISNEY WALT CO COM 254687106 131 1,176 SH   DFND   0 0 1,176
DOCUSIGN INC COM COM 256163106 3,041 58,670 SH   DFND   0 0 58,670
EHEALTH INC COM COM 28238P109 34,493 553,298 SH   DFND   0 0 553,298
ELASTIC N V COM EUR0.01 COM N14506104 9,459 118,428 SH   DFND   0 0 118,428
ELECTRONIC ARTS COM 285512109 187 1,838 SH   DFND   0 0 1,838
ENPHASE ENERGY INC COM USD0.00001 COM 29355A107 41,667 4,514,342 SH   DFND   0 0 4,514,342
ENTERCOM COMMUNICATIONS CORP CL A COM 293639100 5,909 1,125,574 SH   DFND   0 0 1,125,574
EPAM SYS INC COM USD0.001 COM 29414B104 97,568 576,883 SH   DFND   0 0 576,883
EROS INTERNATIONAL COM GBP0.30 COM G3788M114 19,226 2,103,464 SH   DFND   0 0 2,103,464
ESPERION THERAPEUTICS INC COM USD0.001 COM 29664W105 45 1,132 SH   DFND   0 0 1,132
ETSY INC COM COM 29786A106 242,827 3,612,418 SH   DFND   0 0 3,612,418
EVERBRIDGE INC COM COM 29978A104 35,823 477,570 SH   DFND   0 0 477,570
EXACT SCIENCES CORP COM 30063P105 173,707 2,005,394 SH   DFND   0 0 2,005,394
EXTRACTION OIL AND GAS INC COM COM 30227M105 633 149,568 SH   DFND   0 0 149,568
FACEBOOK INC-CLASS A COM 30303M102 179,493 1,076,808 SH   DFND   0 0 1,076,808
FARFETCH LTD COM USD0.04 CLASS A COM 30744W107 93,882 3,488,749 SH   DFND   0 0 3,488,749
FIVE BELOW INC COM COM 33829M101 87,677 705,650 SH   DFND   0 0 705,650
FLEX LNG LTD (BM) USD0.10 ISIN #BMG359472021 SEDOL #BJJMGB2 COM G35947202 6,604 510,490 SH   DFND   0 0 510,490
FLEXION THERAPEUTICS INC COM COM 33938J106 17,003 1,362,386 SH   DFND   0 0 1,362,386
FLOOR &DECOR HLDGS INC CL A COM 339750101 25,050 607,711 SH   DFND   0 0 607,711
FORESCOUT TECHNOLOGIES INC COM COM 34553D101 17,935 427,929 SH   DFND   0 0 427,929
FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31 COM 351858105 5,817 77,503 SH   DFND   0 0 77,503
FRESHPET INC COM COM 358039105 108,750 2,571,525 SH   DFND   0 0 2,571,525
FUSION CONNECT INC COM COM 36116X102 46 35,000 SH   DFND   0 0 35,000
GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5 COM B44170106 47,633 408,289 SH   DFND   0 0 408,289
GASLOG LTD COM USD0.01 COM G37585109 3,121 178,767 SH   DFND   0 0 178,767
GEOPARK LIMITED COM USD0.001 COM G38327105 3,834 221,722 SH   DFND   0 0 221,722
GLAUKOS CORP COM COM 377322102 97,653 1,246,053 SH   DFND   0 0 1,246,053
GLOBANT SA USD1.20 COM L44385109 55,364 775,413 SH   DFND   0 0 775,413
GOGO INC COM COM 38046C109 316 70,320 SH   DFND   0 0 70,320
GOL LINHAS AEREAS INTELIGENTES SA PFD COM 38045R206 5,584 427,916 SH   DFND   0 0 427,916
GOLAR LNG LIMITED COM STK USD1.00 COM G9456A100 10,026 475,405 SH   DFND   0 0 475,405
GOLDMAN SACHS GROUP INC COM USD0.01 COM 38141G104 74,519 388,142 SH   DFND   0 0 388,142
GOOSEHEAD INS INC COM CL A COM 38267D109 43,801 1,571,037 SH   DFND   0 0 1,571,037
GRACE(W.R.)&CO COM USD0.01 COM 38388F108 17,232 220,806 SH   DFND   0 0 220,806
GRUPO FINANCIERO GALICIA SA SPON ADR EACH REP 10 CL B SHS COM 399909100 1,972 77,268 SH   DFND   0 0 77,268
GTT COMMUNICATIONS INC COM USD0.0001 COM 362393100 68,837 1,983,779 SH   DFND   0 0 1,983,779
GUARDANT HEALTH INC COM COM 40131M109 53 686 SH   DFND   0 0 686
GUIDEWIRE SOFTWARE INC COM USD0.0001 COM 40171V100 488 5,021 SH   DFND   0 0 5,021
HDFC BANK LTD SPON ADS EACH REP 3 ORD SHS COM 40415F101 49,005 422,789 SH   DFND   0 0 422,789
HEALTHEQUITY INC COM COM 42226A107 5,545 74,949 SH   DFND   0 0 74,949
HEICO CORP COM 422806109 125 1,322 SH   DFND   0 0 1,322
HEICO CORP COM USD0.01 COM 422806208 210 2,500 SH   DFND   0 0 2,500
HOWARD HUGHES CORP COM COM 44267D107 246 2,239 SH   DFND   0 0 2,239
HUBSPOT INC COM COM 443573100 130,197 783,329 SH   DFND   0 0 783,329
ICICI BANK LIMITED SPON ADR EACH REPR 2 ORD SHS COM 45104G104 4,246 370,539 SH   DFND   0 0 370,539
ILLUMINA INC COM USD0.001 COM 452327109 32,772 105,480 SH   DFND   0 0 105,480
IMPINJ INC COM COM 453204109 778 46,410 SH   DFND   0 0 46,410
INFINERA CORPORATION COM COM 45667G103 472 108,682 SH   DFND   0 0 108,682
INSPIRE MED SYS INC COM COM 457730109 8,495 149,612 SH   DFND   0 0 149,612
INSULET CORP COM COM 45784P101 2,159 22,709 SH   DFND   0 0 22,709
INTUITIVE SURGICAL INC COM NEW COM 46120E602 116,201 203,655 SH   DFND   0 0 203,655
INVITAE CORP COM COM 46185L103 129,513 5,530,037 SH   DFND   0 0 5,530,037
IQIYI INC SPON EACH ADS REP 7 ORD SHS CLASS A COM 46267X108 50 2,097 SH   DFND   0 0 2,097
IRHYTHM TECHNOLOGIES INC COM COM 450056106 8,378 111,761 SH   DFND   0 0 111,761
IROBOT CORP COM COM 462726100 99,376 844,390 SH   DFND   0 0 844,390
JD.COM INC SPON ADS EACH REPR 2 ORD SHS CLASS A COM 47215P106 24,815 823,060 SH   DFND   0 0 823,060
JPMORGAN CHASE &CO. COM USD1.00 COM 46625H100 7,608 75,152 SH   DFND   0 0 75,152
KANSAS CITY SOUTHERN COM COM 485170302 4,640 40,005 SH   DFND   0 0 40,005
KB HOME COM COM 48666K109 191 7,908 SH   DFND   0 0 7,908
KIRKLAND LAKE GOLD COM NPV ISIN #CA49741E1007 SEDOL #BD4G349 COM 49741E100 12,330 405,465 SH   DFND   0 0 405,465
KORNIT DIGITAL LTD ORD ILS0.01 COM M6372Q113 24,737 1,039,382 SH   DFND   0 0 1,039,382
LGI HOMES INC COM COM 50187T106 86,056 1,428,557 SH   DFND   0 0 1,428,557
LHC GROUP INC COM COM 50187A107 10,799 97,407 SH   DFND   0 0 97,407
LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP COM 531229706 4,679 167,471 SH   DFND   0 0 167,471
LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP COM 531229888 17,273 622,017 SH   DFND   0 0 622,017
LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA COM 531229854 4,967 141,698 SH   DFND   0 0 141,698
LILIS ENERGY INC COM NEW COM 532403201 94 80,000 SH   DFND   0 0 80,000
LIVEPERSON INC COM USD0.001 COM 538146101 98,138 3,381,722 SH   DFND   0 0 3,381,722
LONZA GROUP AG-REG ISIN #CH0013841017 SEDOL #7333378 COM H50524133 34,312 110,660 SH   DFND   0 0 110,660
LOVESAC COMPANY COM COM 54738L109 16,298 586,049 SH   DFND   0 0 586,049
LULULEMON ATHLETICA INC COM USD0.005 COM 550021109 5,184 31,632 SH   DFND   0 0 31,632
LUMENTUM HLDGS INC COM COM 55024U109 1,202 21,254 SH   DFND   0 0 21,254
LYFT INC CL A COM COM 55087P104 42,175 538,707 SH   DFND   0 0 538,707
MADISON SQUARE GARDEN CO NEW CL A COM 55825T103 7,314 24,950 SH   DFND   0 0 24,950
MAG SILVER CORP COM NPV ISIN #CA55903Q1046 SEDOL #2581332 COM 55903Q104 17,145 1,608,390 SH   DFND   0 0 1,608,390
MAGENTA THERAPEUTICS INC COM COM 55910K108 30,127 1,829,228 SH   DFND   0 0 1,829,228
MAGNOLIA OIL &GAS CORP CL A COM 559663109 7,546 628,872 SH   DFND   0 0 628,872
MAKEMYTRIP LTD USD0.0005 COM V5633W109 2,770 100,378 SH   DFND   0 0 100,378
MARTIN MARIETTA MATERIALS INC COM USD0.01 COM 573284106 92,039 457,498 SH   DFND   0 0 457,498
MASTERCARD INC CL A COM 57636Q104 22,268 94,578 SH   DFND   0 0 94,578
MATCH GROUP INC COM COM 57665R106 62,917 1,111,407 SH   DFND   0 0 1,111,407
MERCADOLIBRE INC COM USD0.001 COM 58733R102 81,931 161,368 SH   DFND   0 0 161,368
MERCURY SYS INC COM COM 589378108 215 3,350 SH   DFND   0 0 3,350
MESA AIR GROUP INC COM NEW COM 590479135 7,718 925,438 SH   DFND   0 0 925,438
MICROSOFT CORP COM 594918104 68,497 580,778 SH   DFND   0 0 580,778
MIMECAST LIMITED COM USD0.012 COM G14838109 1,584 33,456 SH   DFND   0 0 33,456
MISONIX INC COM 604871103 3,960 205,906 SH   DFND   0 0 205,906
MOLECULAR TEMPLATES INC COM COM 608550109 5,691 979,502 SH   DFND   0 0 979,502
MONGODB INC CL A COM 60937P106 199,641 1,357,916 SH   DFND   0 0 1,357,916
MONOLITHIC PWR SYS INC COM COM 609839105 13,705 101,152 SH   DFND   0 0 101,152
NETFLIX COM INC COM COM 64110L106 561,517 1,574,818 SH   DFND   0 0 1,574,818
NEW PACIFIC METALS CORP COM NPV ISIN #CA6478241012 SEDOL #BF4CP8 COM 647824101 2,225 1,254,245 SH   DFND   0 0 1,254,245
NEW RELIC INC COM COM 64829B100 10,355 104,916 SH   DFND   0 0 104,916
NEW YORK TIMES CO CL A COM 650111107 171,241 5,212,809 SH   DFND   0 0 5,212,809
NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV COM 654445303 16,902 474,214 SH   DFND   0 0 474,214
NIU TECHNOLOGIES SPON ADS EACH REP 2 ORD SHS CL A COM 65481N100 24 2,910 SH   DFND   0 0 2,910
NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST COM 65506L105 37 1,014 SH   DFND   0 0 1,014
NRG ENERGY INC COM NEW COM 629377508 624 14,698 SH   DFND   0 0 14,698
NUVECTRA CORP COM COM 67075N108 11,266 1,023,223 SH   DFND   0 0 1,023,223
NV5 GLOBAL INC COM COM 62945V109 8,502 143,233 SH   DFND   0 0 143,233
NVIDIA CORP COM 67066G104 32,912 183,292 SH   DFND   0 0 183,292
OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74 COM G6718L106 253,430 14,191,164 SH   DFND   0 0 14,191,164
OKTA INC CL A COM 679295105 173,003 2,091,177 SH   DFND   0 0 2,091,177
OVERSTOCK COM INC DEL COM COM 690370101 27 1,623 SH   DFND   0 0 1,623
PALO ALTO NETWORKS INC COM USD0.0001 COM 697435105 18,187 74,879 SH   DFND   0 0 74,879
PARAMOUNT RESOURCES LIMITED COM NPV CLASS A ISIN #CA6993202069 S COM 699320206 909 170,502 SH   DFND   0 0 170,502
PAYPAL HLDGS INC COM COM 70450Y103 23,140 222,845 SH   DFND   0 0 222,845
PDF SOLUTIONS INC COM 693282105 659 53,354 SH   DFND   0 0 53,354
PDVWIRELESS INC COM COM 69290R104 312 8,865 SH   DFND   0 0 8,865
PENSKE AUTOMOTIVE GROUP INC COM 70959W103 3,175 71,109 SH   DFND   0 0 71,109
PENUMBRA INC COM COM 70975L107 6,776 46,094 SH   DFND   0 0 46,094
PINDUODUO INC SPON ADS EACH REP 4 ORD SHS COM 722304102 129 5,200 SH   DFND   0 0 5,200
PIVOTAL SOFTWARE INC COM CL A COM 72582H107 6,882 330,075 SH   DFND   0 0 330,075
PLANET FITNESS INC CL A COM 72703H101 3,094 45,018 SH   DFND   0 0 45,018
PLURALSIGHT INC COM CL A COM 72941B106 4,697 147,989 SH   DFND   0 0 147,989
POOL CORP COM COM 73278L105 63,593 385,482 SH   DFND   0 0 385,482
PROOFPOINT INC COM USD0.0001 COM 743424103 6,064 49,935 SH   DFND   0 0 49,935
Q2 HLDGS INC COM COM 74736L109 21,645 312,511 SH   DFND   0 0 312,511
QUANTERIX CORP COM COM 74766Q101 25,484 986,587 SH   DFND   0 0 986,587
R1 RCM INC COM COM 749397105 5,401 558,487 SH   DFND   0 0 558,487
REECE LIMITED NPV ISIN #AU000000REH4 SEDOL #6728801 COM Q80528138 4,104 585,888 SH   DFND   0 0 585,888
RELIANCE INDUSTRIES SPON GDR EACH REP 2 ORD SHS 144A ISIN #US759 COM ZZC27DZQ8 580 14,454 SH   DFND   0 0 14,454
RIGHTMOVE ORD GBP0.001 ISIN #GB00BGDT3G23 SEDOL #BGDT3G2 COM G7565D106 17,326 2,607,187 SH   DFND   0 0 2,607,187
RINGCENTRAL INC-CLASS A COM 76680R206 230,504 2,138,253 SH   DFND   0 0 2,138,253
ROKU INC COM CL A COM 77543R102 228,477 3,541,731 SH   DFND   0 0 3,541,731
ROYAL GOLD INC COM ISIN #US7802871084 SEDOL #2430553 COM 780287108 18 198 SH   DFND   0 0 198
SAFETY INS GROUP INC COM 78648T100 411 4,720 SH   DFND   0 0 4,720
SALESFORCE.COM INC COM USD0.001 COM 79466L302 99,374 627,482 SH   DFND   0 0 627,482
SAREPTA THERAPEUTICS INC COM COM 803607100 118,281 992,371 SH   DFND   0 0 992,371
SEASPINE HLDGS CORP COM COM 81255T108 361 23,940 SH   DFND   0 0 23,940
SEMLER SCIENTIFIC INC COM USD0.001 COM 81684M104 4,043 94,539 SH   DFND   0 0 94,539
SENESTECH INC COM COM 81720R109 1,511 1,238,750 SH   DFND   0 0 1,238,750
SENSEONICS HLDGS INC COM COM 81727U105 43,469 17,742,518 SH   DFND   0 0 17,742,518
SERVICENOW INC COM USD0.001 COM 81762P102 34,923 141,683 SH   DFND   0 0 141,683
SHAKE SHACK INC CL A COM 819047101 119,736 2,024,283 SH   DFND   0 0 2,024,283
SHERWIN WILLIAMS CO COM 824348106 912 2,117 SH   DFND   0 0 2,117
SHOCKWAVE MED INC COM COM 82489T104 44,601 1,332,559 SH   DFND   0 0 1,332,559
SHOPIFY INC COM NPV CL A ISIN #CA82509L1076 SEDOL #BX865C7 COM 82509L107 59,354 287,263 SH   DFND   0 0 287,263
SHOTSPOTTER INC COM COM 82536T107 84,019 2,176,651 SH   DFND   0 0 2,176,651
SI BONE INC COM COM 825704109 6,682 354,663 SH   DFND   0 0 354,663
SIENTRA INC COM USD0.01 COM 82621J105 3,525 410,827 SH   DFND   0 0 410,827
SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2 COM 828363101 16,648 5,083,284 SH   DFND   0 0 5,083,284
SITEONE LANDSCAPE SUPPLY INC COM COM 82982L103 17,846 312,263 SH   DFND   0 0 312,263
SIX FLAGS ENTMT CORP NEW COM COM 83001A102 4,136 83,816 SH   DFND   0 0 83,816
SKYLINE CHAMPION CORPORATION COM COM 830830105 13 674 SH   DFND   0 0 674
SNAP INC CL A COM 83304A106 1,600 145,175 SH   DFND   0 0 145,175
SOCIAL CAP HEDOSOPHIA HLDGS CORP UNIT 1 CL A & 1/3 WT EXP ISIN # COM G8250R111 1,812 175,605 SH   DFND   0 0 175,605
SOLARIS OILFIELD INFRSTR INC COM CL A COM 83418M103 10,517 639,703 SH   DFND   0 0 639,703
SPLUNK INC COM USD0.001 COM 848637104 6,105 48,995 SH   DFND   0 0 48,995
SPOTIFY TECHNOLOGY S.A. COM EUR0.000625 COM L8681T102 240 1,730 SH   DFND   0 0 1,730
SQUARE INC CL A COM 852234103 136,213 1,818,106 SH   DFND   0 0 1,818,106
SS&C TECHNOLOGIES HLDGS INC COM COM 78467J100 61,814 970,538 SH   DFND   0 0 970,538
STAAR SURGICAL CO COM NEW PAR $0.01 COM 852312305 4,098 119,869 SH   DFND   0 0 119,869
STAR BULK CARRIERS CORP COM USD0.01(POST REV SPLIT) COM Y8162K204 631 95,902 SH   DFND   0 0 95,902
STARS GROUP INC(THE) COM NPV ISIN #CA85570W1005 SEDOL #BDG1MJ0 COM 85570W100 488 27,852 SH   DFND   0 0 27,852
STITCH FIX INC COM CL A COM 860897107 7,799 276,284 SH   DFND   0 0 276,284
STONECO LTD COM USD0.000079365 CLASS A COM G85158106 626 15,218 SH   DFND   0 0 15,218
SUNRUN INC COM COM 86771W105 589 41,859 SH   DFND   0 0 41,859
SVB FINL GROUP COM 78486Q101 13,781 61,975 SH   DFND   0 0 61,975
T MOBILE US INC COM USD0.00001 COM 872590104 89,559 1,296,081 SH   DFND   0 0 1,296,081
TACTILE SYS TECHNOLOGY INC COM COM 87357P100 5,879 111,515 SH   DFND   0 0 111,515
TAKEAWAY.COM N.V. EUR0.04 144A ISIN #NL0012015705 SEDOL #BYQ7HZ6 COM N84437107 226 2,973 SH   DFND   0 0 2,973
TAL EDUCATION GROUP SPON ADS EACH REP 0.3333 CL A ORD SHS COM 874080104 44,408 1,230,829 SH   DFND   0 0 1,230,829
TALEND SA ADS EACH REP 1 ORD SHS COM 874224207 1,753 34,669 SH   DFND   0 0 34,669
TANDEM DIABETES CARE INC COM NEW COM 875372203 34,078 536,654 SH   DFND   0 0 536,654
TELADOC HEALTH INC COM COM 87918A105 82,269 1,479,659 SH   DFND   0 0 1,479,659
TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM COM G87572163 64,797 1,409,006 SH   DFND   0 0 1,409,006
TESLA INC COM COM 88160R101 154,707 552,801 SH   DFND   0 0 552,801
THE A2 MILK COMPANY LTD NPV ISIN #NZATME0002S8 SEDOL #BWSRTS7 COM ZZCXTSUT2 18,558 1,918,118 SH   DFND   0 0 1,918,118
THOR INDS INC COM 885160101 3,129 50,165 SH   DFND   0 0 50,165
TMAC RESOURCES INC COM NPV ISIN #CA8725771015 SEDOL #BYT0622 COM 872577101 1,077 330,611 SH   DFND   0 0 330,611
TRANSDIGM GROUP INC COM COM 893641100 7,303 16,086 SH   DFND   0 0 16,086
TRUPANION INC COM USD0.00001 COM 898202106 5,702 174,169 SH   DFND   0 0 174,169
TWILIO INC CL A COM 90138F102 8,359 64,710 SH   DFND   0 0 64,710
TWITTER INC COM USD0.000005 COM 90184L102 98,995 3,010,798 SH   DFND   0 0 3,010,798
UBIQUITI NETWORKS INC COM USD0.001 COM 90347A100 228 1,525 SH   DFND   0 0 1,525
UNDER ARMOUR INC COM STK USD0.000333 CLASS A COM 904311107 210 9,920 SH   DFND   0 0 9,920
UNITY BIOTECHNOLOGY INC COM COM 91381U101 151 18,598 SH   DFND   0 0 18,598
USA TECHNOLOGIES INC COM NO PAR COM 90328S500 57 13,633 SH   DFND   0 0 13,633
VANECK VECTORS ETF TR GOLD MINERS ETF COM 92189F106 10,095 450,246 SH   DFND   0 0 450,246
VAPOTHERM INC COM COM 922107107 1,328 67,584 SH   DFND   0 0 67,584
VEEVA SYS INC CL A COM COM 922475108 17,942 141,430 SH   DFND   0 0 141,430
VERACYTE INC COM COM 92337F107 86,400 3,453,224 SH   DFND   0 0 3,453,224
VERIZON COMMUNICATIONS COM 92343V104 12,743 215,501 SH   DFND   0 0 215,501
VERRICA PHARMACEUTICALS INC COM COM 92511W108 2,531 234,116 SH   DFND   0 0 234,116
VIEWRAY INC COM COM 92672L107 4,344 587,784 SH   DFND   0 0 587,784
VULCAN MATERIALS CO COM 929160109 4,921 41,566 SH   DFND   0 0 41,566
WHEATON PRECIOUS METALS CORP COM NPV ISIN #CA9628791027 SEDOL #B COM 962879102 1,926 80,843 SH   DFND   0 0 80,843
WILLSCOT CORP COM COM 971375126 992 89,433 SH   DFND   0 0 89,433
WORKDAY INC COM USD0.001 CL A COM 98138H101 30,828 159,855 SH   DFND   0 0 159,855
WORLD WRESTLING ENTERTAINMENT INC CL A COM 98156Q108 114,686 1,321,573 SH   DFND   0 0 1,321,573
WUXI BIOLOGICS (CAYMAN) INC USD0.000025 144A REG S ISIN #KYG9700 COM G97008109 14,267 1,466,856 SH   DFND   0 0 1,466,856
XILINX INC COM 983919101 30,857 243,374 SH   DFND   0 0 243,374
ZAI LAB LIMITED ADS EACH REP 1 ORD SHS COM 98887Q104 26,652 903,159 SH   DFND   0 0 903,159
ZAYO GROUP HLDGS INC COM COM 98919V105 11,395 400,946 SH   DFND   0 0 400,946
ZENDESK INC COM USD0.01 COM 98936J101 12,001 141,192 SH   DFND   0 0 141,192
ZILLOW GROUP INC CL A COM 98954M101 361 10,554 SH   DFND   0 0 10,554
ZUORA INC COM CL A COM 98983V106 39,578 1,975,935 SH   DFND   0 0 1,975,935