The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLION PHARMACEUTICALS COM 00448Q201 1,839 621,182 SH   SOLE 621,182 0 0
ADVAXIS INC COM NEW 007624307 1,195 202,222 SH   SOLE 202,222 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 7,209 151,770 SH   SOLE 151,770 0 0
AILERON THERAPEUTICS INC COM 00887A105 194 99,502 SH   SOLE 99,502 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 5,860 715,538 SH   SOLE 715,538 0 0
ALDER BIOPHARMACEUTICALS INC NOTE 2.500% 2/0 014339AA3 240 250,000 PRN   SOLE 250,000 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 7,794 571,013 SH   SOLE 571,013 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 452 50,000 SH   SOLE 50,000 0 0
ALECTOR INC COM 014442107 918 49,063 SH   SOLE 49,063 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 1,505 359,190 SH   SOLE 359,190 0 0
ARBUTUS BIOPHARMA CORP COM 03879J100 884 246,900 SH   SOLE 246,900 0 0
ARCTURUS THERAPEUTICS LTD SHS M1492T105 323 47,255 SH   SOLE 47,255 0 0
ARDELYX INC COM 039697107 1,895 676,759 SH   SOLE 676,759 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 4,211 93,942 SH   SOLE 93,942 0 0
ARGENX SE SPONSORED ADR 04016X101 4,451 35,650 SH   SOLE 35,650 0 0
ARQULE INC COM 04269E107 1,787 373,164 SH   SOLE 373,164 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 5,224 44,380 SH   SOLE 44,380 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 996 50,573 SH   SOLE 50,573 0 0
ATRICURE INC COM 04963C209 8,539 318,729 SH   SOLE 318,729 0 0
BELLICUM PHARMACEUTICALS INC COM 079481107 101 30,000 SH   SOLE 30,000 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 4,057 498,415 SH   SOLE 498,415 0 0
BIOHAVEN PHARMACEUTICALS HOLD COM G11196105 4,118 80,000 SH   SOLE 80,000 0 0
BIOTELEMETRY INC COM 090672106 2,179 34,800 SH   SOLE 34,800 0 0
BIOTIME INC COM 09066L105 124 95,000 SH   SOLE 95,000 0 0
BLUEBIRD BIO INC COM 09609G100 4,248 27,000 SH   SOLE 27,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 9,583 119,718 SH   SOLE 119,718 0 0
CARA THERAPEUTICS INC COM 140755109 2,818 143,611 SH   SOLE 143,611 0 0
CARDIOVASCULAR SYSTEMS INC COM 141619106 2,173 56,200 SH   SOLE 56,200 0 0
CIDARA THERAPEUTICS INC COM 171757107 564 212,766 SH   SOLE 212,766 0 0
CORBUS PHARMACEUTICALS HLDGS COM 21833P103 2,120 305,000 SH   SOLE 305,000 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 3,703 278,811 SH   SOLE 278,811 0 0
CYTOKINETICS INC COM NEW 23282W605 3,238 400,294 SH   SOLE 400,294 0 0
DERMIRA INC COM 24983L104 969 71,500 SH   SOLE 71,500 0 0
DEXCOM INC COM 252131107 3,851 32,338 SH   SOLE 32,338 0 0
DEXCOM INC NOTE 0.750% 5/1 252131AF4 336 250,000 PRN   SOLE 250,000 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 1,807 123,314 SH   SOLE 123,314 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 3,030 808,000 SH   SOLE 808,000 0 0
GALAPAGOS NV SPON ADR 36315X101 5,843 49,609 SH   SOLE 49,609 0 0
GENOCEA BIOSCIENCES INC COM 372427104 1,174 1,989,653 SH   SOLE 1,989,653 0 0
IMMUNOMEDICS INC COM 452907108 97 5,052 SH   SOLE 5,052 0 0
INOGEN INC COM 45780L104 944 9,900 SH   SOLE 9,900 0 0
INSULET CORP NOTE 1.375% 45784PAG6 1,811 1,500,000 PRN   SOLE 1,500,000 0 0
INTEC PHARMA LTD JERUSALEM SHS M53644106 2,799 381,789 SH   SOLE 381,789 0 0
ISHARES TR NASDAQ BIOTECH ETF 464287556 6,865 61,400 SH   SOLE 61,400 0 0
JOHNSON AND JOHNSON COM 478160104 1,314 9,400 SH   SOLE 9,400 0 0
KADMON HOLDINGS INC COM 48283N106 1,999 757,177 SH   SOLE 757,177 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 665 23,225 SH   SOLE 23,225 0 0
KURA ONCOLOGY INC COM 50127T109 606 36,558 SH   SOLE 36,558 0 0
LUMINEX CORP COM 55027E102 3,184 138,391 SH   SOLE 138,391 0 0
MACROGENICS INC COM 556099109 899 50,000 SH   SOLE 50,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 827 6,600 SH   SOLE 6,600 0 0
MASIMO CORPORATION COM 574795100 415 3,000 SH   SOLE 3,000 0 0
MENLO THERAPEUTICS INC COM 586858102 4,710 600,030 SH   SOLE 600,030 0 0
MERSANA THERAPEUTICS INC COM 59045L106 2,121 403,300 SH   SOLE 403,300 0 0
MINERVA NEUROSCIENCES INC COM 603380106 284 36,084 SH   SOLE 36,084 0 0
NATUS MEDICAL INC COM 639050103 1,089 42,900 SH   SOLE 42,900 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 4,846 55,008 SH   SOLE 55,008 0 0
NEVRO CORP COM 64157F103 1,951 31,210 SH   SOLE 31,210 0 0
OBSEVA SA COM H5861P103 555 43,408 SH   SOLE 43,408 0 0
ORAMED PHARMACEUTICALS INC COM NEW 68403P203 95 26,000 SH   SOLE 26,000 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 689 72,500 SH   SOLE 72,500 0 0
PROQR THERAPEUTICS N V SHS EURO N71542109 3,627 261,521 SH   SOLE 261,521 0 0
RADIUS HEALTH INC COM NEW 750469207 837 42,000 SH   SOLE 42,000 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 3,336 4,000,000 PRN   SOLE 4,000,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 354 137,600 SH   SOLE 137,600 0 0
SAGE THERAPEUTICS INC COM 78667J108 19,691 123,806 SH   SOLE 123,806 0 0
SAVARA INC COM 805111101 813 110,275 SH   SOLE 110,275 0 0
SCYNEXIS INC COM 811292101 1,922 1,272,927 SH   SOLE 1,272,927 0 0
SOL GEL TECHNOLOGIES LTD SHS M8694L103 237 35,000 SH   SOLE 35,000 0 0
SPERO THERAPEUTICS INC COM 84833T103 897 70,000 SH   SOLE 70,000 0 0
STEREOTAXIS INC COM 85916J409 26,677 13,680,554 SH   SOLE 13,680,554 0 0
SUTRO BIOPHARMA INC COM 869367102 359 31,494 SH   SOLE 31,494 0 0
UROGEN PHARMA LTD COM M96088105 554 15,000 SH   SOLE 15,000 0 0
VBI VACCINES INC COM NEW 91822J103 1,590 850,000 SH   SOLE 850,000 0 0
VIKING THERAPEUTICS INC COM 92686J106 1,781 179,200 SH   SOLE 179,200 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 7,403 190,554 SH   SOLE 190,554 0 0
XENON PHARMACEUTICALS INC COM 98420N105 3,360 330,667 SH   SOLE 330,667 0 0
ZAFGEN INC COM 98885E103 910 332,000 SH   SOLE 332,000 0 0
ZOGENIX INC COM NEW 98978L204 7,138 129,764 SH   SOLE 129,764 0 0