The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACER THERAPEUTICS INC COM 00444P108 471 19,367 SH   DFND   19,367 0 0
ADAMIS PHARMACEUTICALS CORP COM NEW 00547W208 1,794 850,000 SH   DFND   850,000 0 0
ADECOAGRO S A COM L00849106 2,412 350,000 SH   DFND   350,000 0 0
ADIENT PLC ORD SHS G0084W101 6,960 537,000 SH   DFND   537,000 0 0
ADMA BIOLOGICS INC COM 000899104 3,051 805,000 SH   DFND   805,000 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 1,899 362,386 SH   DFND   362,386 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 16,254 1,800,000 SH   DFND   1,800,000 0 0
ALLEGRO MERGER CORP *W EXP 01/06/202 01749N111 115 443,772 SH   DFND   443,772 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 30,465 326,000 SH   DFND   326,000 0 0
AMCI ACQUISITION CORP *W EXP 05/20/202 00165R119 59 200,000 SH   DFND   200,000 0 0
APHRIA INC COM 03765K104 1,398 150,000 SH   DFND   150,000 0 0
APHRIA INC COM 03765K104 1,398 150,000 SH Put DFND   150,000 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 838 200,000 SH   DFND   200,000 0 0
APTEVO THERAPEUTICS INC COM 03835L108 518 575,000 SH   DFND   575,000 0 0
ARDELYX INC COM 039697107 2,902 1,036,404 SH   DFND   1,036,404 0 0
ARYA SCIENCES ACQUISITION CO SHS CL A G3165V109 9,830 1,000,000 SH   DFND   1,000,000 0 0
ARYA SCIENCES ACQUISITION CO *W EXP 10/10/202 G3165V125 600 500,000 SH   DFND   500,000 0 0
AT&T INC COM 00206R102 38 1,200 SH Put DFND   1,200 0 0
AZURRX BIOPHARMA INC COM 05502L105 1,683 695,504 SH   DFND   695,504 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 5,022 25,000 SH Put DFND   25,000 0 0
BIG ROCK PARTNERS ACQUISI CO RIGHT 12/01/2022 089482129 43 165,000 SH   DFND   165,000 0 0
BIG ROCK PARTNERS ACQUISI CO *W EXP 12/01/202 089482111 15 82,500 SH   DFND   82,500 0 0
BIOCERES CROP SOLUTIONS CORP *W EXP 07/01/202 G1117K106 54 200,000 SH   DFND   200,000 0 0
BISON CAP ACQUISITION CORP RIGHT 03/20/2019 G1142P138 35 100,000 SH   DFND   100,000 0 0
BISON CAP ACQUISITION CORP *W EXP 06/20/202 G1142P112 10 50,000 SH   DFND   50,000 0 0
BLACK RIDGE ACQUISITION CORP RIGHT 07/10/2019 09216T123 70 200,000 SH   DFND   200,000 0 0
BLACK RIDGE ACQUISITION CORP *W EXP 07/10/202 09216T115 210 700,000 SH   DFND   700,000 0 0
BLACKSTONE GROUP L P COM UNIT LTD 09253U108 5,945 170,000 SH   DFND   170,000 0 0
BP PRUDHOE BAY RTY TR UNIT BEN INT 055630107 1,697 63,800 SH Put DFND   63,800 0 0
BRIGHTHOUSE FINL INC COM 10922N103 1,811 49,900 SH   DFND   49,900 0 0
CAPITAL ONE FINL CORP COM 14040H105 20,096 246,000 SH   DFND   246,000 0 0
CAPITAL ONE FINL CORP COM 14040H105 8,169 100,000 SH Put DFND   100,000 0 0
CAPITAL PRODUCT PARTNERS L P PARTNERSHP UNITS Y11082206 4 363 SH   DFND   363 0 0
CARVANA CO CL A 146869102 114,088 1,965,000 SH   DFND   1,965,000 0 0
CHARDAN HEALTHCARE ACQUISITI COM 15957A108 1,469 150,000 SH   DFND   150,000 0 0
CHARDAN HEALTHCARE ACQUISITI *W EXP 12/13/202 15957A116 74 150,000 SH   DFND   150,000 0 0
CHASERG TECHNLGY ACQUISITN C *W EXP 04/10/202 16166A111 49 75,000 SH   DFND   75,000 0 0
CHIMERIX INC COM 16934W106 630 300,000 SH   DFND   300,000 0 0
CM SEVEN STAR ACQUISITION CO RIGHT 08/21/2022 G2345N136 58 175,000 SH   DFND   175,000 0 0
CM SEVEN STAR ACQUISITION CO *W EXP 08/21/202 G2345N110 0 87,500 SH   DFND   87,500 0 0
COCA COLA CO COM 191216100 23,430 500,000 SH Put DFND   500,000 0 0
CONSTELLATION ALPHA CAP CORP RIGHT 99/99/9999 G2379F132 23 180,000 SH   DFND   180,000 0 0
CONSTELLATION ALPHA CAP CORP *W EXP 03/23/202 G2379F116 30 380,000 SH   DFND   380,000 0 0
CONTRAFECT CORP COM 212326102 994 2,500,000 SH   DFND   2,500,000 0 0
CONTURA ENERGY INC COM 21241B100 3,859 66,625 SH   DFND   66,625 0 0
COOPER STD HLDGS INC COM 21676P103 1,174 25,000 SH   DFND   25,000 0 0
CRESUD S A C I F Y A SPONSORED ADR 226406106 9,815 846,860 SH   DFND   846,860 0 0
DHT HOLDINGS INC SHS NEW Y2065G121 2,297 515,000 SH   DFND   515,000 0 0
DIAMOND S SHIPPING INC COM Y20676105 1,048 100,726 SH   DFND   100,726 0 0
DIANA SHIPPING INC COM Y2066G104 769 272,622 SH   DFND   272,622 0 0
EDTECHX HLDGS ACQUISITION CO *W EXP 12/31/202 28138X111 24 125,000 SH   DFND   125,000 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 22,515 1,610,529 SH   DFND   1,610,529 0 0
ELEVATE CREDIT INC COM 28621V101 1,779 410,000 SH   DFND   410,000 0 0
ENERGY RECOVERY INC COM 29270J100 9,603 1,100,000 SH   DFND   1,100,000 0 0
ENOVA INTL INC COM 29357K103 14,091 617,498 SH   DFND   617,498 0 0
ESTRE AMBIENTAL INC *W EXP 12/21/202 G3206V118 85 730,000 SH   DFND   730,000 0 0
FALCON MINERALS CORP *W EXP 07/21/202 30607B208 124 149,600 SH   DFND   149,600 0 0
FATE THERAPEUTICS INC COM 31189P102 6,940 395,000 SH   DFND   395,000 0 0
FENNEC PHARMACEUTICALS INC COM 31447P100 4,711 971,351 SH   DFND   971,351 0 0
FERRARI N V COM N3167Y103 3,345 25,000 SH Put DFND   25,000 0 0
FORUM MERGER II CORP *W EXP 09/30/202 34986F111 132 300,000 SH   DFND   300,000 0 0
GALMED PHARMACEUTICALS LTD SHS M47238106 11,030 1,350,000 SH   DFND   1,350,000 0 0
GENCO SHIPPING & TRADING LTD SHS Y2685T131 1,328 178,000 SH   DFND   178,000 0 0
GIGCAPITAL INC RIGHT 03/06/2020 37518N114 130 200,000 SH   DFND   200,000 0 0
GIGCAPITAL INC *W EXP 06/08/202 37518N122 43 150,000 SH   DFND   150,000 0 0
GLOBALSTAR INC COM 378973408 6,928 16,110,778 SH   DFND   16,110,778 0 0
GORDON POINTE ACQUISITION CO *W EXP 07/30/202 382788115 86 225,000 SH   DFND   225,000 0 0
GRAF INDL CORP *W EXP 12/31/202 384278115 74 225,000 SH   DFND   225,000 0 0
GREENLAND ACQUISITIN CORPORA RIGHT 04/27/2025 G40981113 47 150,000 SH   DFND   150,000 0 0
GREENLAND ACQUISITIN CORPORA *W EXP 03/03/202 G40981105 15 150,000 SH   DFND   150,000 0 0
GREIF INC CL B 397624206 582 11,910 SH   DFND   11,910 0 0
GRUPO FINANCIERO GALICIA S A SPONSORED ADR 399909100 2,680 105,000 SH   DFND   105,000 0 0
HL ACQUISITIONS CORP RIGHT 07/17/2023 G4603R130 52 180,000 SH   DFND   180,000 0 0
HL ACQUISITIONS CORP *W EXP 06/21/202 G4603R122 45 180,000 SH   DFND   180,000 0 0
HOSTESS BRANDS INC *W EXP 11/04/202 44109J114 3,276 2,520,000 SH   DFND   2,520,000 0 0
IFRESH INC COM 449538107 35 30,000 SH   DFND   30,000 0 0
INSPIRED ENTMT INC COM 45782N108 5,344 801,824 SH   DFND   801,824 0 0
INTEC PHARMA LTD JERUSALEM SHS M53644106 1,100 150,000 SH   DFND   150,000 0 0
INTERNATIONAL BUSINESS MACHS COM 459200101 10,583 75,000 SH Put DFND   75,000 0 0
IRSA INVERSIONES Y REP S A GLOBL DEP RCPT 450047204 9,752 894,724 SH   DFND   894,724 0 0
IRSA PROPIEDADES COMERCIALES SPONSORED ADR 463588103 3,314 159,700 SH   DFND   159,700 0 0
ISHARES TR IBOXX HI YD ETF 464288513 8,647 100,000 SH Put DFND   100,000 0 0
JOHNSON & JOHNSON COM 478160104 55,916 400,000 SH Put DFND   400,000 0 0
KADMON HLDGS INC COM 48283N106 884 334,900 SH   DFND   334,900 0 0
KROGER CO COM 501044101 5,043 205,000 SH   DFND   205,000 0 0
KROGER CO COM 501044101 9,840 400,000 SH Call DFND   400,000 0 0
LEAP THERAPEUTICS INC COM 52187K101 281 150,142 SH   DFND   150,142 0 0
LEGACY ACQUISITION CORP *W EXP 11/30/202 524643111 150 500,000 SH   DFND   500,000 0 0
LEISURE ACQUISITION CORP *W EXP 12/05/201 52539T115 75 125,000 SH   DFND   125,000 0 0
LF CAP ACQUISITION CORP *W EXP 06/22/202 50200K116 173 450,000 SH   DFND   450,000 0 0
M D C HLDGS INC COM 552676108 8,718 300,000 SH Put DFND   300,000 0 0
MACROGENICS INC COM 556099109 8,720 484,970 SH   DFND   484,970 0 0
MAGNOLIA OIL & GAS CORP *W EXP 07/31/202 559663117 1,072 316,333 SH   DFND   316,333 0 0
MAIDEN HOLDINGS LTD SHS G5753U112 5,850 7,876,964 SH   DFND   7,876,964 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 5,852 1,400,000 SH   DFND   1,400,000 0 0
MARKER THERAPEUTICS INC COM 57055L107 9,636 1,460,000 SH   DFND   1,460,000 0 0
MEDICINES CO COM 584688105 4,675 167,252 SH   DFND   167,252 0 0
MEGALITH FINL ACQUISITION CO *W EXP 08/26/202 58518F117 110 400,000 SH   DFND   400,000 0 0
MEIRAGTX HOLDINGS PLC COM G59665102 6,420 432,319 SH   DFND   432,319 0 0
MERCK & CO INC COM 58933Y105 16,634 200,000 SH Put DFND   200,000 0 0
MICRON TECHNOLOGY INC COM 595112103 14,879 360,000 SH   DFND   360,000 0 0
MIRAGEN THERAPEUTICS INC COM 60463E103 4,927 1,766,038 SH   DFND   1,766,038 0 0
MODERN MEDIA ACQUISITION RIGHT 99/99/9999 60765P129 330 1,000,000 SH   DFND   1,000,000 0 0
MODERN MEDIA ACQUISITION *W EXP 05/17/202 60765P111 155 500,000 SH   DFND   500,000 0 0
MONDELEZ INTL INC CL A 609207105 9,984 200,000 SH Put DFND   200,000 0 0
MONTAGE RES CORP COM 61179L100 174 11,571 SH   DFND   11,571 0 0
MTECH ACQUISITION CORP *W EXP 08/01/202 55378W115 48 75,000 SH   DFND   75,000 0 0
MUDRICK CAP ACQUISITION CORP COM CLASS A 624745105 19,152 1,900,000 SH   DFND   1,900,000 0 0
MUDRICK CAP ACQUISITION CORP *W EXP 02/12/202 624745113 1,375 2,500,000 SH   DFND   2,500,000 0 0
NATIONAL ENERGY SERVICES REU *W EXP 05/05/202 G6375R115 827 725,000 SH   DFND   725,000 0 0
NATIONAL OILWELL VARCO INC COM 637071101 3,463 130,000 SH   DFND   130,000 0 0
NAVIOS MARITIME CONTAINERS L COM UNIT RP LP Y62151108 4,917 2,057,185 SH   DFND   2,057,185 0 0
NAVIOS MARITIME HLDGS INC COM Y62197119 321 135,000 SH   DFND   135,000 0 0
NEW FRONTIER CORP *W EXP 99/99/999 G6485P124 35 50,000 SH   DFND   50,000 0 0
NII HLDGS INC COM PAR 62913F508 25,800 13,163,432 SH   DFND   13,163,432 0 0
NRC GROUP HLDGS CORP *W EXP 10/17/202 629375114 484 537,500 SH   DFND   537,500 0 0
ON DECK CAP INC COM 682163100 16,938 3,125,000 SH   DFND   3,125,000 0 0
ONCONOVA THERAPEUTICS INC COM PAR 68232V405 3,191 966,877 SH   DFND   966,877 0 0
ONCOSEC MED INC COM NEW 68234L207 167 300,000 SH   DFND   300,000 0 0
ONE MADISON CORP *W EXP 99/99/999 G6772P126 146 125,000 SH   DFND   125,000 0 0
OPES ACQUISITION CORP *W EXP 03/13/202 68373P118 37 150,000 SH   DFND   150,000 0 0
ORACLE CORP COM 68389X105 10,742 200,000 SH Put DFND   200,000 0 0
OTONOMY INC COM 68906L105 2,893 1,100,000 SH   DFND   1,100,000 0 0
PENSARE ACQUISITION CORP RIGHT 99/99/9999 70957E121 175 605,000 SH   DFND   605,000 0 0
PENSARE ACQUISITION CORP *W EXP 07/27/202 70957E113 23 115,000 SH   DFND   115,000 0 0
PG&E CORP COM 69331C108 46,066 2,588,000 SH   DFND   2,588,000 0 0
PHUNWARE INC *W EXP 12/26/202 71948P118 446 269,396 SH   DFND   269,396 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 503 150,257 SH   DFND   150,257 0 0
PROCTER AND GAMBLE CO COM 742718109 10,405 100,000 SH Put DFND   100,000 0 0
REDHILL BIOPHARMA LTD SPONSORED ADS 757468103 30,696 3,693,840 SH   DFND   3,693,840 0 0
SCHULTZE SPL PURP ACQUSTN CO *W EXP 12/31/202 80821R117 101 300,000 SH   DFND   300,000 0 0
SCORPIO TANKERS INC NOTE 3.000% 5/1 80918TAB5 1,748 2,000,000 PRN   DFND   2,000,000 0 0
SCORPIO TANKERS INC SHS Y7542C130 29,760 1,500,000 SH   DFND   1,500,000 0 0
SEADRILL LTD COM G7998G106 6,207 746,951 SH   DFND   746,951 0 0
SELECT SECTOR SPDR TR SBI INT-UTILS 81369Y886 29,085 500,000 SH Put DFND   500,000 0 0
SELLAS LIFE SCIENCES GROUP I COM 81642T100 1,301 1,275,000 SH   DFND   1,275,000 0 0
SEQUENTIAL BRNDS GROUP INC N COM 81734P107 3,838 2,998,060 SH   DFND   2,998,060 0 0
SIERRA ONCOLOGY INC COM 82640U107 3,956 2,313,159 SH   DFND   2,313,159 0 0
SOLENO THERAPEUTICS INC COM NEW 834203200 1,172 569,087 SH   DFND   569,087 0 0
SPDR SERIES TRUST S&P RETAIL ETF 78464A714 3,376 75,000 SH Put DFND   75,000 0 0
STRONGBRIDGE BIOPHARMA PLC SHS USD G85347105 4,227 848,700 SH   DFND   848,700 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 8,391 1,598,357 SH   DFND   1,598,357 0 0
SYNTHETIC BIOLOGICS INC COM NEW 87164U201 29 42,858 SH   DFND   42,858 0 0
TEEKAY TANKERS LTD CL A Y8565N102 970 1,000,000 SH   DFND   1,000,000 0 0
TENZING ACQUISITION CORP *W EXP 02/23/202 G8708A108 32 200,000 SH   DFND   200,000 0 0
TESLA INC COM 88160R101 139,958 500,100 SH Put DFND   500,100 0 0
TETRAPHASE PHARMACEUTICALS I COM 88165N105 1,126 840,000 SH   DFND   840,000 0 0
TG THERAPEUTICS INC COM 88322Q108 4,221 525,000 SH   DFND   525,000 0 0
TIBERIUS ACQUISITION CORP *W EXP 02/28/202 88633A115 198 450,000 SH   DFND   450,000 0 0
TKK SYMPHONY ACQUISITION COR RIGHT 02/20/2020 G88950137 56 225,000 SH   DFND   225,000 0 0
TKK SYMPHONY ACQUISITION COR *W EXP 02/20/202 G88950129 33 225,000 SH   DFND   225,000 0 0
TOCAGEN INC COM 888846102 4,076 375,000 SH   DFND   375,000 0 0
TOTTENHAM ACQUISITION I LTD RIGHT 06/05/2020 G8959N122 43 134,000 SH   DFND   134,000 0 0
TOTTENHAM ACQUISITION I LTD *W EXP 05/06/202 G8959N114 87 542,000 SH   DFND   542,000 0 0
TRACON PHARMACEUTICALS INC COM 89237H100 3,752 2,738,938 SH   DFND   2,738,938 0 0
TRIDENT ACQUISITIONS CORP *W EXP 05/09/202 89615T114 319 1,993,750 SH   DFND   1,993,750 0 0
TRINITY MERGER CORP *W EXP 05/11/202 89653L114 252 700,000 SH   DFND   700,000 0 0
TRIVAGO N V SPON ADS A SHS 89686D105 14,910 3,451,402 SH   DFND   3,451,402 0 0
TRUECAR INC COM 89785L107 14,317 2,156,191 SH   DFND   2,156,191 0 0
TWELVE SEAS INVESTMENT COMPA RIGHT 12/22/2019 G9145A131 47 175,000 SH   DFND   175,000 0 0
TWELVE SEAS INVESTMENT COMPA *W EXP 12/22/202 G9145A115 151 581,850 SH   DFND   581,850 0 0
U S WELL SVCS INC CL A 91274U101 223 28,000 SH   DFND   28,000 0 0
UNIQURE NV SHS N90064101 44,738 750,000 SH   DFND   750,000 0 0
VECTOIQ ACQUISITION CORP *W EXP 05/11/202 92243N111 215 500,000 SH   DFND   500,000 0 0
WARRIOR MET COAL INC COM 93627C101 7,448 245,000 SH   DFND   245,000 0 0
ZAFGEN INC COM 98885E103 3,658 1,335,104 SH   DFND   1,335,104 0 0
ZILLOW GROUP INC CL A 98954M101 1,710 50,000 SH   DFND   50,000 0 0
ZIOPHARM ONCOLOGY INC COM 98973P101 770 200,000 SH   DFND   200,000 0 0
ZOGENIX INC COM NEW 98978L204 2,751 50,000 SH   DFND   50,000 0 0