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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
SERES THERAPEUTICS INC COM 81750R102 87,131 12,682,876 SH   DFND 2 0 12,682,876 0
SYROS PHARMACEUTICALS INC COM 87184Q107 29,289 3,204,437 SH   DFND 2 0 3,204,437 0
QUANTERIX CORP COM 74766Q101 52,448 2,030,495 SH   DFND   0 2,030,495 0
DENALI THERAPEUTICS INC COM 24823R105 185,893 8,005,747 SH   DFND 1 0 8,005,747 0
EVELO BIOSCIENCES INC COM 299734103 23,761 2,970,119 SH   DFND 2 0 2,970,119 0
EVELO BIOSCIENCES INC COM 299734103 102,807 12,850,919 SH   DFND 1 0 12,850,919 0
EVELO BIOSCIENCES INC COM 299734103 19,299 2,412,365 SH   DFND   0 2,412,365 0
RUBIUS THERAPEUTICS INC COM 78116T103 437,187 24,153,995 SH   DFND 2 0 24,153,995 0
RUBIUS THERAPEUTICS INC COM 78116T103 209,577 11,578,828 SH   DFND 1 0 11,578,828 0
RUBIUS THERAPEUTICS INC COM 78116T103 46,403 2,563,703 SH   DFND   0 2,563,703 0
MODERNA INC COM 60770K107 1,196,650 58,803,455 SH   DFND 2 0 58,803,455 0
MODERNA INC COM 60770K107 80 3,924 SH   DFND   0 3,924 0
KALEIDO BIOSCIENCES INC COM 483347100 14,355 989,976 SH   DFND 2 0 989,976 0
KALEIDO BIOSCIENCES INC COM 483347100 177,770 12,259,979 SH   DFND 1 0 12,259,979 0
KALEIDO BIOSCIENCES INC COM 483347100 59,606 4,110,755 SH   DFND   0 4,110,755 0