The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abbott Laboratories COM 002824100 51,651 646,119 SH   SOLE 0 528,886 0 117,233
Abbott Laboratories COM 002824100 26,841 335,760 SH   DFND 1 335,760 0 0
Abbott Laboratories COM 002824100 173,510 2,170,500 SH   OTR 2 0 2,170,500 0
Adobe Inc COM 00724F101 101,712 381,674 SH   SOLE 0 312,662 0 69,012
Adobe Inc COM 00724F101 51,906 194,776 SH   DFND 1 194,776 0 0
Adobe Inc COM 00724F101 338,869 1,271,600 SH   OTR 2 0 1,271,600 0
Agilent Technologies Inc COM 00846U101 44,762 556,886 SH   SOLE 0 455,286 0 101,600
Agilent Technologies Inc COM 00846U101 24,899 309,760 SH   DFND 1 309,760 0 0
Agilent Technologies Inc COM 00846U101 155,708 1,937,150 SH   OTR 2 0 1,937,150 0
Alibaba Group Holding Ltd Sp A COM 01609W102 82,767 453,642 SH   SOLE 0 370,728 0 82,914
Alibaba Group Holding Ltd Sp A COM 01609W102 43,660 239,300 SH   DFND 1 239,300 0 0
Alibaba Group Holding Ltd Sp A COM 01609W102 284,093 1,557,100 SH   OTR 2 0 1,557,100 0
Align Technology Inc COM 016255101 48,706 171,304 SH   SOLE 0 140,464 0 30,840
Align Technology Inc COM 016255101 25,217 88,690 SH   DFND 1 88,690 0 0
Align Technology Inc COM 016255101 163,120 573,700 SH   OTR 2 0 573,700 0
Alphabet Inc Cl A COM 02079K305 113,100 96,101 SH   SOLE 0 78,731 0 17,370
Alphabet Inc Cl A COM 02079K305 59,442 50,508 SH   DFND 1 50,508 0 0
Alphabet Inc Cl A COM 02079K305 387,544 329,295 SH   OTR 2 0 329,295 0
Alphabet Inc Cl C COM 02079K107 114,261 97,383 SH   SOLE 0 79,718 0 17,665
Alphabet Inc Cl C COM 02079K107 60,069 51,196 SH   DFND 1 51,196 0 0
Alphabet Inc Cl C COM 02079K107 391,381 333,570 SH   OTR 2 0 333,570 0
Amazon Com Inc COM 023135106 238,275 133,806 SH   SOLE 0 109,329 0 24,477
Amazon Com Inc COM 023135106 125,614 70,540 SH   DFND 1 70,540 0 0
Amazon Com Inc COM 023135106 820,018 460,490 SH   OTR 2 0 460,490 0
AstraZeneca PLC Sp ADR COM 046353108 46,664 1,154,186 SH   SOLE 0 917,111 0 237,075
AstraZeneca PLC Sp ADR COM 046353108 27,430 678,460 SH   DFND 1 678,460 0 0
AstraZeneca PLC Sp ADR COM 046353108 178,680 4,419,500 SH   OTR 2 0 4,419,500 0
Automatic Data Process COM 053015103 61,352 384,075 SH   SOLE 0 315,172 0 68,903
Automatic Data Process COM 053015103 31,835 199,290 SH   DFND 1 199,290 0 0
Automatic Data Process COM 053015103 206,688 1,293,900 SH   OTR 2 0 1,293,900 0
Becton Dickinson & Co COM 075887109 44,561 178,436 SH   SOLE 0 147,874 0 30,562
Becton Dickinson & Co COM 075887109 23,260 93,140 SH   DFND 1 93,140 0 0
Becton Dickinson & Co COM 075887109 144,906 580,250 SH   OTR 2 0 580,250 0
Costar Group Inc COM 22160N109 44,648 95,726 SH   SOLE 0 78,726 0 17,000
Costar Group Inc COM 22160N109 21,925 47,007 SH   DFND 1 47,007 0 0
Costar Group Inc COM 22160N109 149,075 319,615 SH   OTR 2 0 319,615 0
Electronic Arts Inc COM 285512109 45,283 445,572 SH   SOLE 0 364,023 0 81,549
Electronic Arts Inc COM 285512109 23,811 234,290 SH   DFND 1 234,290 0 0
Electronic Arts Inc COM 285512109 156,139 1,536,350 SH   OTR 2 0 1,536,350 0
Exact Sciences Corp COM 30063P105 40,339 465,691 SH   SOLE 0 379,864 0 85,827
Exact Sciences Corp COM 30063P105 20,603 237,850 SH   DFND 1 237,850 0 0
Exact Sciences Corp COM 30063P105 140,446 1,621,400 SH   OTR 2 0 1,621,400 0
Expedia Inc COM 30212P303 38,261 321,521 SH   SOLE 0 264,411 0 57,110
Expedia Inc COM 30212P303 19,587 164,600 SH   DFND 1 164,600 0 0
Expedia Inc COM 30212P303 127,791 1,073,870 SH   OTR 2 0 1,073,870 0
Facebook Inc COM 30303M102 118,558 711,247 SH   SOLE 0 582,591 0 128,656
Facebook Inc COM 30303M102 61,742 370,400 SH   DFND 1 370,400 0 0
Facebook Inc COM 30303M102 402,781 2,416,350 SH   OTR 2 0 2,416,350 0
Ferrari NV COM N3167Y103 62,935 470,371 SH   SOLE 0 386,549 0 83,822
Ferrari NV COM N3167Y103 32,263 241,130 SH   DFND 1 241,130 0 0
Ferrari NV COM N3167Y103 210,340 1,572,050 SH   OTR 2 0 1,572,050 0
Fiserv Inc COM 337738108 47,663 539,910 SH   SOLE 0 442,606 0 97,304
Fiserv Inc COM 337738108 24,642 279,140 SH   DFND 1 279,140 0 0
Fiserv Inc COM 337738108 160,043 1,812,900 SH   OTR 2 0 1,812,900 0
Fortive Corporation COM 34959J108 38,862 463,254 SH   SOLE 0 380,907 0 82,347
Fortive Corporation COM 34959J108 19,841 236,514 SH   DFND 1 236,514 0 0
Fortive Corporation COM 34959J108 128,125 1,527,300 SH   OTR 2 0 1,527,300 0
Godaddy Inc Cl A COM 380237107 60,207 800,732 SH   SOLE 0 657,271 0 143,461
Godaddy Inc Cl A COM 380237107 30,990 412,150 SH   DFND 1 412,150 0 0
Godaddy Inc Cl A COM 380237107 202,972 2,699,450 SH   OTR 2 0 2,699,450 0
Honeywell International COM 438516106 42,817 269,427 SH   SOLE 0 219,884 0 49,543
Honeywell International COM 438516106 23,436 147,470 SH   DFND 1 147,470 0 0
Honeywell International COM 438516106 150,369 946,190 SH   OTR 2 0 946,190 0
Illumina Inc COM 452327109 58,423 188,042 SH   SOLE 0 154,491 0 33,551
Illumina Inc COM 452327109 30,830 99,230 SH   DFND 1 99,230 0 0
Illumina Inc COM 452327109 199,221 641,220 SH   OTR 2 0 641,220 0
Intercontinental Exch COM 45866F104 41,430 544,126 SH   SOLE 0 446,118 0 98,008
Intercontinental Exch COM 45866F104 20,611 270,700 SH   DFND 1 270,700 0 0
Intercontinental Exch COM 45866F104 140,299 1,842,650 SH   OTR 2 0 1,842,650 0
Intuit COM 461202103 88,110 337,058 SH   SOLE 0 277,092 0 59,966
Intuit COM 461202103 45,200 172,910 SH   DFND 1 172,910 0 0
Intuit COM 461202103 294,086 1,125,000 SH   OTR 2 0 1,125,000 0
Intuitive Surgical Inc COM 46120E602 57,134 100,134 SH   SOLE 0 82,000 0 18,134
Intuitive Surgical Inc COM 46120E602 28,580 50,090 SH   DFND 1 50,090 0 0
Intuitive Surgical Inc COM 46120E602 194,414 340,730 SH   OTR 2 0 340,730 0
Lilly Eli & Co COM 532457108 47,629 367,054 SH   SOLE 0 304,701 0 62,353
Lilly Eli & Co COM 532457108 23,926 184,390 SH   DFND 1 184,390 0 0
Lilly Eli & Co COM 532457108 154,382 1,189,750 SH   OTR 2 0 1,189,750 0
Linde PLC COM G5494J103 55,748 316,875 SH   SOLE 0 260,490 0 56,385
Linde PLC COM G5494J103 28,524 162,130 SH   DFND 1 162,130 0 0
Linde PLC COM G5494J103 186,055 1,057,550 SH   OTR 2 0 1,057,550 0
Lowes Cos Inc COM 548661107 94,976 867,595 SH   SOLE 0 709,404 0 158,191
Lowes Cos Inc COM 548661107 49,885 455,700 SH   DFND 1 455,700 0 0
Lowes Cos Inc COM 548661107 325,192 2,970,600 SH   OTR 2 0 2,970,600 0
Lyft Inc Cl A COM 55087P104 4,024 51,400 SH   SOLE 0 35,500 0 15,900
Lyft Inc Cl A COM 55087P104 3,492 44,600 SH   DFND 1 44,600 0 0
Lyft Inc Cl A COM 55087P104 23,800 304,000 SH   OTR 2 0 304,000 0
Mastercard Inc COM 57636Q104 118,588 503,664 SH   SOLE 0 414,912 0 88,752
Mastercard Inc COM 57636Q104 60,259 255,930 SH   DFND 1 255,930 0 0
Mastercard Inc COM 57636Q104 392,943 1,668,900 SH   OTR 2 0 1,668,900 0
MercadoLibre Inc COM 58733R102 38,705 76,232 SH   SOLE 0 62,588 0 13,644
MercadoLibre Inc COM 58733R102 20,101 39,590 SH   DFND 1 39,590 0 0
MercadoLibre Inc COM 58733R102 130,086 256,210 SH   OTR 2 0 256,210 0
Microsoft Corp COM 594918104 267,638 2,269,271 SH   SOLE 0 1,864,802 0 404,469
Microsoft Corp COM 594918104 139,736 1,184,810 SH   DFND 1 1,184,810 0 0
Microsoft Corp COM 594918104 907,401 7,693,750 SH   OTR 2 0 7,693,750 0
Moodys Corp COM 615369105 70,081 386,991 SH   SOLE 0 317,294 0 69,697
Moodys Corp COM 615369105 36,352 200,740 SH   DFND 1 200,740 0 0
Moodys Corp COM 615369105 236,837 1,307,840 SH   OTR 2 0 1,307,840 0
Netflix Inc COM 64110L106 79,313 222,440 SH   SOLE 0 182,768 0 39,672
Netflix Inc COM 64110L106 40,865 114,610 SH   DFND 1 114,610 0 0
Netflix Inc COM 64110L106 265,637 745,000 SH   OTR 2 0 745,000 0
Nike Inc COM 654106103 100,257 1,190,557 SH   SOLE 0 975,684 0 214,873
Nike Inc COM 654106103 52,089 618,562 SH   DFND 1 618,562 0 0
Nike Inc COM 654106103 340,048 4,038,100 SH   OTR 2 0 4,038,100 0
Northrop Grumman Corp COM 666807102 44,201 163,949 SH   SOLE 0 131,904 0 32,045
Northrop Grumman Corp COM 666807102 24,197 89,750 SH   DFND 1 89,750 0 0
Northrop Grumman Corp COM 666807102 164,726 611,000 SH   OTR 2 0 611,000 0
Pagseguro Digital Ltd Cl A COM G68707101 49,094 1,644,666 SH   SOLE 0 1,350,203 0 294,463
Pagseguro Digital Ltd Cl A COM G68707101 24,270 813,050 SH   DFND 1 813,050 0 0
Pagseguro Digital Ltd Cl A COM G68707101 165,163 5,533,100 SH   OTR 2 0 5,533,100 0
Paypal Holdings Inc COM 70450Y103 105,762 1,018,509 SH   SOLE 0 835,487 0 183,022
Paypal Holdings Inc COM 70450Y103 54,782 527,560 SH   DFND 1 527,560 0 0
Paypal Holdings Inc COM 70450Y103 356,602 3,434,150 SH   OTR 2 0 3,434,150 0
Raytheon Co COM 755111507 35,862 196,958 SH   SOLE 0 157,768 0 39,190
Raytheon Co COM 755111507 19,938 109,500 SH   DFND 1 109,500 0 0
Raytheon Co COM 755111507 135,650 745,000 SH   OTR 2 0 745,000 0
Salesforce Com Inc COM 79466L302 125,643 793,348 SH   SOLE 0 652,249 0 141,099
Salesforce Com Inc COM 79466L302 64,530 407,465 SH   DFND 1 407,465 0 0
Salesforce Com Inc COM 79466L302 420,061 2,652,400 SH   OTR 2 0 2,652,400 0
Sherwin Williams Co COM 824348106 36,842 85,536 SH   SOLE 0 70,650 0 14,886
Sherwin Williams Co COM 824348106 18,663 43,330 SH   DFND 1 43,330 0 0
Sherwin Williams Co COM 824348106 120,252 279,195 SH   OTR 2 0 279,195 0
Stryker Corp COM 863667101 71,868 363,853 SH   SOLE 0 297,397 0 66,456
Stryker Corp COM 863667101 35,810 181,300 SH   DFND 1 181,300 0 0
Stryker Corp COM 863667101 243,779 1,234,200 SH   OTR 2 0 1,234,200 0
Thermo Fisher Scientific COM 883556102 67,837 247,832 SH   SOLE 0 204,760 0 43,072
Thermo Fisher Scientific COM 883556102 33,065 120,800 SH   DFND 1 120,800 0 0
Thermo Fisher Scientific COM 883556102 224,998 822,000 SH   OTR 2 0 822,000 0
Union Pacific Corp COM 907818108 59,572 356,288 SH   SOLE 0 293,428 0 62,860
Union Pacific Corp COM 907818108 30,537 182,640 SH   DFND 1 182,640 0 0
Union Pacific Corp COM 907818108 196,401 1,174,650 SH   OTR 2 0 1,174,650 0
Unitedhealth Group Inc COM 91324P102 121,208 490,205 SH   SOLE 0 396,457 0 93,748
Unitedhealth Group Inc COM 91324P102 65,013 262,932 SH   DFND 1 262,932 0 0
Unitedhealth Group Inc COM 91324P102 442,363 1,789,060 SH   OTR 2 0 1,789,060 0
Veeva Systems Inc Cl A COM 922475108 43,902 346,066 SH   SOLE 0 283,083 0 62,983
Veeva Systems Inc Cl A COM 922475108 22,774 179,520 SH   DFND 1 179,520 0 0
Veeva Systems Inc Cl A COM 922475108 147,760 1,164,750 SH   OTR 2 0 1,164,750 0
Visa Inc COM 92826C839 189,736 1,214,780 SH   SOLE 0 1,000,431 0 214,349
Visa Inc COM 92826C839 96,474 617,668 SH   DFND 1 617,668 0 0
Visa Inc COM 92826C839 629,938 4,033,150 SH   OTR 2 0 4,033,150 0
Workday Inc COM 98138H101 25,285 131,115 SH   SOLE 0 107,268 0 23,847
Workday Inc COM 98138H101 13,598 70,510 SH   DFND 1 70,510 0 0
Workday Inc COM 98138H101 86,204 447,000 SH   OTR 2 0 447,000 0
Xilinx Inc COM 983919101 50,105 395,188 SH   SOLE 0 324,939 0 70,249
Xilinx Inc COM 983919101 25,780 203,330 SH   DFND 1 203,330 0 0
Xilinx Inc COM 983919101 167,198 1,318,700 SH   OTR 2 0 1,318,700 0
Zoetis Inc COM 98978V103 72,022 715,424 SH   SOLE 0 586,571 0 128,853
Zoetis Inc COM 98978V103 37,063 368,160 SH   DFND 1 368,160 0 0
Zoetis Inc COM 98978V103 240,012 2,384,150 SH   OTR 2 0 2,384,150 0
American Tower Corp REIT 03027X100 36,711 186,295 SH   SOLE 0 152,343 0 33,952
American Tower Corp REIT 03027X100 19,669 99,812 SH   DFND 1 99,812 0 0
American Tower Corp REIT 03027X100 125,783 638,300 SH   OTR 2 0 638,300 0
Centene Corp COM 15135B101 3,648 68,700 SH   SOLE 0 62,550 0 6,150
Centene Corp COM 15135B101 1,448 27,270 SH   DFND 1 27,270 0 0
Ecolab Inc COM 278865100 2,133 12,084 SH   SOLE 0 11,499 0 585
Ecolab Inc COM 278865100 1,056 5,980 SH   DFND 1 5,980 0 0
Seaspan Corp COM Y75638109 911 104,700 SH   SOLE 0 104,700 0 0
Seaspan Corp COM Y75638109 476 54,700 SH   DFND 1 54,700 0 0
CME Group Inc COM 12572Q105 861 5,230 SH   SOLE 0 5,230 0 0
CAE Inc COM 124765108 1,287 58,050 SH   DFND 1 58,050 0 0
CAE Inc COM 124765108 673 30,350 SH   SOLE 0 30,350 0 0
Kirkland Lake Gold Ltd COM 49741E100 1,095 36,010 SH   DFND 1 36,010 0 0
Kirkland Lake Gold Ltd COM 49741E100 576 18,950 SH   DFND 1 18,950 0 0
ICL-Israel Chem ILS COM M5920A109 829 156,800 SH   SOLE 0 156,800 0 0
ICL-Israel Chem ILS COM M5920A109 436 82,370 SH   DFND 1 82,370 0 0
Eventbrite Inc Cl A COM 29975E109 18,123 945,407 SH   SOLE 0 945,407 0 0
ISHARES TR RSSLL 1000 GRWT ETF-EQUITY 464287614 10,494 69,332 SH   SOLE 0 69,332 0 0