The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101 12,480 65,500 SH Put DFND   65,500 0 0
ACER THERAPEUTICS INC COM 00444P108 390 19,367 SH   DFND   19,367 0 0
ACHILLION PHARMACEUTICALS IN COM 00448Q201 1,590 1,000,000 SH   DFND   1,000,000 0 0
ADAMIS PHARMACEUTICALS CORP COM NEW 00547W208 1,913 850,000 SH   DFND   850,000 0 0
ADECOAGRO S A COM L00849106 2,436 350,000 SH   DFND   350,000 0 0
ADIENT PLC ORD SHS G0084W101 17,952 1,192,000 SH   DFND   1,192,000 0 0
ADMA BIOLOGICS INC COM 000899104 1,924 805,000 SH   DFND   805,000 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 1,142 362,386 SH   DFND   362,386 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 11,568 1,393,700 SH   DFND   1,393,700 0 0
ALLEGRO MERGER CORP *W EXP 01/06/202 01749N111 133 443,772 SH   DFND   443,772 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 23,769 326,000 SH   DFND   326,000 0 0
ALTRIA GROUP INC COM 02209S103 4,939 100,000 SH Put DFND   100,000 0 0
AMCI ACQUISITION CORP UNIT 01/07/2019 00165R200 1,990 200,000 SH   DFND   200,000 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 498 200,000 SH   DFND   200,000 0 0
ARDELYX INC COM 039697107 1,624 907,114 SH   DFND   907,114 0 0
ARYA SCIENCES ACQUISITION CO SHS CL A G3165V109 9,800 1,000,000 SH   DFND   1,000,000 0 0
ARYA SCIENCES ACQUISITION CO *W EXP 10/10/202 G3165V125 800 500,000 SH   DFND   500,000 0 0
AT&T INC COM 00206R102 4,281 150,000 SH Put DFND   150,000 0 0
AVEO PHARMACEUTICALS INC COM 053588109 3,000 1,875,000 SH   DFND   1,875,000 0 0
AZURRX BIOPHARMA INC COM 05502L105 842 695,504 SH   DFND   695,504 0 0
BIG ROCK PARTNERS ACQUISI CO RIGHT 12/01/2022 089482129 59 165,000 SH   DFND   165,000 0 0
BIG ROCK PARTNERS ACQUISI CO *W EXP 12/01/202 089482111 32 82,500 SH   DFND   82,500 0 0
BISON CAP ACQUISITION CORP RIGHT 03/20/2019 G1142P138 28 100,000 SH   DFND   100,000 0 0
BISON CAP ACQUISITION CORP *W EXP 06/20/202 G1142P112 12 50,000 SH   DFND   50,000 0 0
BLACK RIDGE ACQUISITION CORP RIGHT 07/10/2019 09216T123 60 200,000 SH   DFND   200,000 0 0
BLACK RIDGE ACQUISITION CORP *W EXP 07/10/202 09216T115 224 700,000 SH   DFND   700,000 0 0
BLACKSTONE GROUP L P COM UNIT LTD 09253U108 5,068 170,000 SH   DFND   170,000 0 0
BRIGHTHOUSE FINL INC COM 10922N103 1,588 52,100 SH   DFND   52,100 0 0
CAPITAL ONE FINL CORP COM 14040H105 18,595 246,000 SH   DFND   246,000 0 0
CAPITAL ONE FINL CORP COM 14040H105 7,559 100,000 SH Put DFND   100,000 0 0
CARVANA CO CL A 146869102 60,841 1,860,000 SH   DFND   1,860,000 0 0
CATERPILLAR INC DEL COM 149123101 9,530 75,000 SH Put DFND   75,000 0 0
CHARDAN HEALTHCARE ACQUISITI UNIT 12/13/2023 15957A207 1,511 150,000 SH   DFND   150,000 0 0
CHASERG TECHNLGY ACQUISITN C *W EXP 04/10/202 16166A111 55 75,000 SH   DFND   75,000 0 0
CHIMERIX INC COM 16934W106 771 300,000 SH   DFND   300,000 0 0
CM SEVEN STAR ACQUISITION CO RIGHT 08/21/2022 G2345N136 70 175,000 SH   DFND   175,000 0 0
CM SEVEN STAR ACQUISITION CO *W EXP 08/21/202 G2345N110 22 75,000 SH   DFND   75,000 0 0
COCA COLA CO COM 191216100 28,410 600,000 SH Put DFND   600,000 0 0
CONCRETE PUMPING HLDGS INC *W EXP 08/01/202 206704116 963 1,234,606 SH   DFND   1,234,606 0 0
CONSTELLATION ALPHA CAP CORP RIGHT 99/99/9999 G2379F132 34 180,000 SH   DFND   180,000 0 0
CONSTELLATION ALPHA CAP CORP *W EXP 03/23/202 G2379F116 50 380,000 SH   DFND   380,000 0 0
CONTRAFECT CORP COM 212326102 3,488 2,280,000 SH   DFND   2,280,000 0 0
CONTURA ENERGY INC COM 21241B100 4,380 66,625 SH   DFND   66,625 0 0
CRESUD S A C I F Y A SPONSORED ADR 226406106 10,570 870,000 SH   DFND   870,000 0 0
DESPEGAR COM CORP ORD SHS G27358103 4,344 350,000 SH   DFND   350,000 0 0
DHT HOLDINGS INC SHS NEW Y2065G121 1,823 465,000 SH   DFND   465,000 0 0
DIANA SHIPPING INC COM Y2066G104 867 272,622 SH   DFND   272,622 0 0
DRAPER OAKWOOD TECHNOLOGY *W EXP 09/19/202 26146L111 17 85,200 SH   DFND   85,200 0 0
EDTECHX HLDGS ACQUISITION CO *W EXP 12/31/202 28138X111 44 125,000 SH   DFND   125,000 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 16,363 1,610,529 SH   DFND   1,610,529 0 0
ELEVATE CREDIT INC COM 28621V101 4,683 1,045,305 SH   DFND   1,045,305 0 0
ENERGY RECOVERY INC COM 29270J100 7,403 1,100,000 SH   DFND   1,100,000 0 0
ENOVA INTL INC COM 29357K103 11,481 590,000 SH   DFND   590,000 0 0
ESTRE AMBIENTAL INC *W EXP 12/21/202 G3206V118 60 750,000 SH   DFND   750,000 0 0
EVOKE PHARMA INC COM 30049G104 283 114,300 SH   DFND   114,300 0 0
EXACT SCIENCES CORP COM 30063P105 6,310 100,000 SH Put DFND   100,000 0 0
EXPEDIA GROUP INC COM NEW 30212P303 4,506 40,000 SH Put DFND   40,000 0 0
FACEBOOK INC CL A 30303M102 6,555 50,000 SH Put DFND   50,000 0 0
FALCON MINERALS CORP *W EXP 07/21/202 30607B208 90 149,600 SH   DFND   149,600 0 0
FATE THERAPEUTICS INC COM 31189P102 5,196 405,000 SH   DFND   405,000 0 0
FENNEC PHARMACEUTICALS INC COM 31447P100 6,197 971,351 SH   DFND   971,351 0 0
FERRARI N V COM N3167Y103 159 1,600 SH   DFND   1,600 0 0
FERRARI N V COM N3167Y103 12,430 125,000 SH Call DFND   125,000 0 0
FERRARI N V COM N3167Y103 33,810 340,000 SH Put DFND   340,000 0 0
FORUM MERGER II CORP *W EXP 09/30/202 34986F111 135 300,000 SH   DFND   300,000 0 0
GALMED PHARMACEUTICALS LTD SHS M47238106 9,221 1,350,000 SH   DFND   1,350,000 0 0
GENCO SHIPPING & TRADING LTD SHS Y2685T131 933 118,200 SH   DFND   118,200 0 0
GIGCAPITAL INC RIGHT 03/06/2020 37518N114 55 200,000 SH   DFND   200,000 0 0
GIGCAPITAL INC *W EXP 06/08/202 37518N122 38 150,000 SH   DFND   150,000 0 0
GLOBALSTAR INC COM 378973408 10,306 16,110,778 SH   DFND   16,110,778 0 0
GORDON POINTE ACQUISITION CO *W EXP 07/30/202 382788115 88 225,000 SH   DFND   225,000 0 0
GRAF INDL CORP *W EXP 12/31/202 384278115 90 225,000 SH   DFND   225,000 0 0
GREENLAND ACQUISITIN CORPORA RIGHT 04/27/2025 G40981113 68 150,000 SH   DFND   150,000 0 0
GREENLAND ACQUISITIN CORPORA *W EXP 03/03/202 G40981105 30 150,000 SH   DFND   150,000 0 0
GREIF INC CL B 397624206 529 11,910 SH   DFND   11,910 0 0
GRUBHUB INC COM 400110102 7,681 100,000 SH Put DFND   100,000 0 0
GRUPO FINANCIERO GALICIA-ADR SP ADR 10 SH B 399909100 2,895 105,000 SH   DFND   105,000 0 0
HAYMAKER ACQUISITION CORP *W EXP 10/27/202 420870115 312 380,000 SH   DFND   380,000 0 0
HERBALIFE NUTRITION LTD COM SHS G4412G101 17,685 300,000 SH Put DFND   300,000 0 0
HL ACQUISITIONS CORP RIGHT 07/17/2023 G4603R130 136 180,000 SH   DFND   180,000 0 0
HL ACQUISITIONS CORP *W EXP 06/21/202 G4603R122 54 180,000 SH   DFND   180,000 0 0
HOSTESS BRANDS INC *W EXP 11/04/202 44109J114 2,341 2,520,000 SH   DFND   2,520,000 0 0
IFRESH INC COM 449538107 26 30,000 SH   DFND   30,000 0 0
INSPIRED ENTMT INC COM 45782N108 3,849 801,824 SH   DFND   801,824 0 0
INTEC PHARMA LTD JERUSALEM SHS M53644106 1,131 150,000 SH   DFND   150,000 0 0
INVESCO SR INCOME TR COM 46131H107 21,780 1,000,000 SH Put DFND   1,000,000 0 0
IRSA INVERSIONES Y REP S A GLOBL DEP RCPT 450047204 11,685 894,724 SH   DFND   894,724 0 0
IRSA PROPIEDADES COMERCIALES SPONSORED ADR 463588103 1,299 72,050 SH   DFND   72,050 0 0
ISHARES TR IBOXX HI YD ETF 464288513 16,220 200,000 SH Put DFND   200,000 0 0
JOHNSON & JOHNSON COM 478160104 83,883 650,000 SH Put DFND   650,000 0 0
KADMON HLDGS INC COM 48283N106 697 334,900 SH   DFND   334,900 0 0
KELLOGG CO COM 487836108 21,379 375,000 SH Put DFND   375,000 0 0
KROGER CO COM 501044101 8,388 305,000 SH   DFND   305,000 0 0
KROGER CO COM 501044101 11,000 400,000 SH Call DFND   400,000 0 0
LEAP THERAPEUTICS INC COM 52187K101 300 150,000 SH   DFND   150,000 0 0
LEGACY ACQUISITION CORP *W EXP 11/30/202 524643111 166 500,000 SH   DFND   500,000 0 0
LEISURE ACQUISITION CORP *W EXP 12/05/201 52539T115 99 125,000 SH   DFND   125,000 0 0
LF CAP ACQUISITION CORP *W EXP 06/22/202 50200K116 194 450,000 SH   DFND   450,000 0 0
M D C HLDGS INC COM 552676108 2,811 100,000 SH Put DFND   100,000 0 0
MACROGENICS INC COM 556099109 4,889 384,970 SH   DFND   384,970 0 0
MAGNOLIA OIL & GAS CORP *W EXP 07/31/202 559663117 1,034 341,333 SH   DFND   341,333 0 0
MAIDEN HOLDINGS LTD SHS G5753U112 701 425,000 SH   DFND   425,000 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 3,875 1,350,000 SH   DFND   1,350,000 0 0
MARKER THERAPEUTICS INC COM 57055L107 8,103 1,460,000 SH   DFND   1,460,000 0 0
MEDICINES CO COM 584688105 3,201 167,252 SH   DFND   167,252 0 0
MEGALITH FINL ACQUISITION CO CL A COM 58518F109 1,940 200,000 SH   DFND   200,000 0 0
MEGALITH FINL ACQUISITION CO *W EXP 08/26/202 58518F117 160 400,000 SH   DFND   400,000 0 0
MEIRAGTX HOLDINGS PLC COM G59665102 675 70,000 SH   DFND   70,000 0 0
MICRON TECHNOLOGY INC COM 595112103 11,423 360,000 SH   DFND   360,000 0 0
MIRAGEN THERAPEUTICS INC COM 60463E103 5,142 1,697,038 SH   DFND   1,697,038 0 0
MODERN MEDIA ACQUISITION RIGHT 99/99/9999 60765P129 250 1,000,000 SH   DFND   1,000,000 0 0
MODERN MEDIA ACQUISITION *W EXP 05/17/202 60765P111 135 500,000 SH   DFND   500,000 0 0
MONDELEZ INTL INC CL A 609207105 4,003 100,000 SH Put DFND   100,000 0 0
MTECH ACQUISITION CORP *W EXP 08/01/202 55378W115 45 75,000 SH   DFND   75,000 0 0
MUDRICK CAP ACQUISITION CORP COM CLASS A 624745105 18,772 1,900,000 SH   DFND   1,900,000 0 0
MUDRICK CAP ACQUISITION CORP *W EXP 02/12/202 624745113 1,125 2,500,000 SH   DFND   2,500,000 0 0
NATIONAL ENERGY SERVICES REU *W EXP 05/05/202 G6375R115 870 725,000 SH   DFND   725,000 0 0
NATIONAL OILWELL VARCO INC COM 637071101 3,341 130,000 SH   DFND   130,000 0 0
NAVIOS MARITIME CONTAINERS L COM UNIT RP LP Y62151108 5,553 1,962,199 SH   DFND   1,962,199 0 0
NAVIOS MARITIME HOLDINGS INC COM Y62196103 82 300,000 SH   DFND   300,000 0 0
NETFLIX INC COM 64110L106 53,532 200,000 SH Put DFND   200,000 0 0
NEW FRONTIER CORP *W EXP 99/99/999 G6485P124 45 50,000 SH   DFND   50,000 0 0
NEXEO SOLUTIONS INC *W EXP 06/09/202 65342H110 420 1,050,000 SH   DFND   1,050,000 0 0
NII HLDGS INC COM PAR 62913F508 58,051 13,163,432 SH   DFND   13,163,432 0 0
NRC GROUP HLDGS CORP *W EXP 10/17/202 629375114 435 537,500 SH   DFND   537,500 0 0
ON DECK CAP INC COM 682163100 17,995 3,050,000 SH   DFND   3,050,000 0 0
ONCONOVA THERAPEUTICS INC COM PAR 68232V405 2,040 966,877 SH   DFND   966,877 0 0
ONCOSEC MED INC COM NEW 68234L207 192 300,000 SH   DFND   300,000 0 0
ONE MADISON CORP *W EXP 99/99/999 G6772P126 97 125,000 SH   DFND   125,000 0 0
OPES ACQUISITION CORP *W EXP 03/13/202 68373P118 44 150,000 SH   DFND   150,000 0 0
ORACLE CORP COM 68389X105 4,515 100,000 SH Put DFND   100,000 0 0
OTONOMY INC COM 68906L105 2,035 1,100,000 SH   DFND   1,100,000 0 0
PENSARE ACQUISITION CORP RIGHT 99/99/9999 70957E121 175 605,000 SH   DFND   605,000 0 0
PENSARE ACQUISITION CORP *W EXP 07/27/202 70957E113 23 115,000 SH   DFND   115,000 0 0
PERNIX THERAPEUTICS HLDGS IN DBCV 4.250% 4/0 71426VAK4 68 9,000,000 PRN   DFND   9,000,000 0 0
PFIZER INC COM 717081103 13,095 300,000 SH Put DFND   300,000 0 0
PG&E CORP COM 69331C108 15,796 665,101 SH   DFND   665,101 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 400 150,257 SH   DFND   150,257 0 0
POLARITYTE INC COM 731094108 9,185 680,900 SH   DFND   680,900 0 0
PROCTER AND GAMBLE CO COM 742718109 27,576 300,000 SH Put DFND   300,000 0 0
REDHILL BIOPHARMA LTD SPONSORED ADS 757468103 20,501 3,693,840 SH   DFND   3,693,840 0 0
RUMBLEON INC CL B 781386206 1,413 300,000 SH   DFND   300,000 0 0
SCHULTZE SPL PURP ACQUISITIO UNIT 12/31/2023 80821R208 2,985 300,000 SH   DFND   300,000 0 0
SCORPIO TANKERS INC NOTE 3.000% 5/1 80918TAB5 1,563 2,000,000 PRN   DFND   2,000,000 0 0
SCORPIO TANKERS INC SHS Y7542C106 21,878 12,430,435 SH   DFND   12,430,435 0 0
SEADRILL LTD COM G7998G106 697 69,649 SH   DFND   69,649 0 0
SELECT SECTOR SPDR TR SBI CONS STPLS 81369Y308 19,043 375,000 SH Put DFND   375,000 0 0
SELECT SECTOR SPDR TR SBI INT-UTILS 81369Y886 41,278 780,000 SH Put DFND   780,000 0 0
SELLAS LIFE SCIENCES GROUP I COM 81642T100 2,337 1,900,000 SH   DFND   1,900,000 0 0
SEQUENTIAL BRNDS GROUP INC N COM 81734P107 2,685 3,356,200 SH   DFND   3,356,200 0 0
SIERRA ONCOLOGY INC COM 82640U107 2,869 2,173,620 SH   DFND   2,173,620 0 0
SMAAASH ENTERTAINMENT INC COM 831550108 41 20,000 SH   DFND   20,000 0 0
SMAAASH ENTERTAINMENT INC *W EXP 05/22/202 831550116 122 700,000 SH   DFND   700,000 0 0
SOLENO THERAPEUTICS INC COM NEW 834203200 1,443 844,112 SH   DFND   844,112 0 0
SOLENO THERAPEUTICS INC *W EXP 11/12/201 834203135 186 602,443 SH   DFND   602,443 0 0
SPDR SERIES TRUST S&P REGL BKG 78464A698 4,679 100,000 SH Put DFND   100,000 0 0
SPDR SERIES TRUST S&P RETAIL ETF 78464A714 4,099 100,000 SH Call DFND   100,000 0 0
SPDR SERIES TRUST S&P RETAIL ETF 78464A714 12,297 300,000 SH Put DFND   300,000 0 0
STRONGBRIDGE BIOPHARMA PLC SHS USD G85347105 3,802 848,700 SH   DFND   848,700 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 5,976 1,342,839 SH   DFND   1,342,839 0 0
SYNTHETIC BIOLOGICS INC COM NEW 87164U201 24 42,858 SH   DFND   42,858 0 0
TEEKAY TANKERS LTD CL A Y8565N102 464 500,000 SH   DFND   500,000 0 0
TENZING ACQUISITION CORP *W EXP 02/23/202 G8708A108 66 200,000 SH   DFND   200,000 0 0
TESLA INC COM 88160R101 464,456 1,395,600 SH Put DFND   1,395,600 0 0
TETRAPHASE PHARMACEUTICALS I COM 88165N105 893 790,571 SH   DFND   790,571 0 0
TG THERAPEUTICS INC COM 88322Q108 2,050 500,000 SH   DFND   500,000 0 0
TIBERIUS ACQUISITION CORP *W EXP 02/28/202 88633A115 176 450,000 SH   DFND   450,000 0 0
TIFFANY & CO NEW COM 886547108 16,102 200,000 SH Put DFND   200,000 0 0
TKK SYMPHONY ACQUISITION COR ORD SHS G88950103 2,171 225,000 SH   DFND   225,000 0 0
TKK SYMPHONY ACQUISITION COR RIGHT 02/20/2020 G88950137 79 225,000 SH   DFND   225,000 0 0
TKK SYMPHONY ACQUISITION COR *W EXP 02/20/202 G88950129 34 225,000 SH   DFND   225,000 0 0
TOCAGEN INC COM 888846102 3,079 375,000 SH   DFND   375,000 0 0
TOTTENHAM ACQUISITION I LTD RIGHT 06/05/2020 G8959N122 54 134,000 SH   DFND   134,000 0 0
TOTTENHAM ACQUISITION I LTD *W EXP 05/06/202 G8959N114 108 542,000 SH   DFND   542,000 0 0
TRACON PHARMACEUTICALS INC COM 89237H100 1,726 2,738,938 SH   DFND   2,738,938 0 0
TRIDENT ACQUISITIONS CORP *W EXP 05/09/202 89615T114 598 1,993,750 SH   DFND   1,993,750 0 0
TRINITY MERGER CORP *W EXP 05/11/202 89653L114 277 700,000 SH   DFND   700,000 0 0
TRIVAGO N V SPON ADS A SHS 89686D105 31,528 5,600,000 SH   DFND   5,600,000 0 0
TRUECAR INC COM 89785L107 31,333 3,458,358 SH   DFND   3,458,358 0 0
TWELVE SEAS INVESTMENT COMPA RIGHT 12/22/2019 G9145A131 61 175,000 SH   DFND   175,000 0 0
TWELVE SEAS INVESTMENT COMPA *W EXP 12/22/202 G9145A115 151 581,850 SH   DFND   581,850 0 0
U S WELL SVCS INC *W EXP 03/15/202 91274U119 480 800,000 SH   DFND   800,000 0 0
UNION ACQUISITION CORP RIGHT 12/02/2019 G9366W135 76 200,000 SH   DFND   200,000 0 0
UNION ACQUISITION CORP *W EXP 07/01/202 G9366W127 50 200,000 SH   DFND   200,000 0 0
UNIQURE NV SHS N90064101 31,270 1,085,000 SH   DFND   1,085,000 0 0
VECTOIQ ACQUISITION CORP *W EXP 05/11/202 92243N111 250 500,000 SH   DFND   500,000 0 0
WARRIOR MET COAL INC COM 93627C101 5,907 245,000 SH   DFND   245,000 0 0
WRIGHT MED GROUP N V RIGHT 03/01/2019 N96617126 2 169,532 SH   DFND   169,532 0 0
ZAFGEN INC COM 98885E103 6,930 1,400,000 SH   DFND   1,400,000 0 0
ZOGENIX INC COM NEW 98978L204 1,823 50,000 SH   DFND   50,000 0 0