The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 91,455 2,100,000 SH   OTR   2,100,000 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 143,924 1,050,000 SH   OTR   1,050,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 40,101 550,000 SH   OTR   550,000 0 0
ALPHABET INC CAP STK CL C 02079K107 480,942 464,405 SH   OTR   464,405 0 0
ALTABA INC COM 021346101 1,599,568 27,607,317 SH   OTR   27,607,317 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 47,635 3,500,000 SH   OTR   3,500,000 0 0
ANHEUSER BUSCH INBEV SA/NV SPONSORED ADR 03524A108 18,153 275,843 SH   OTR   275,843 0 0
ANTHEM INC COM 036752103 275,762 1,050,000 SH   OTR   1,050,000 0 0
APTINYX INC COM 03836N103 11,082 670,000 SH   OTR   670,000 0 0
ARRAY BIOPHARMA INC COM 04269X105 81,938 5,750,000 SH   OTR   5,750,000 0 0
ARRIS INTL INC SHS G0551A103 109,441 3,580,000 SH   OTR   3,580,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 18,630 1,500,000 SH   OTR   1,500,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 93,931 1,499,297 SH   OTR   1,499,297 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 7,917 350,000 SH   OTR   350,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 147,552 3,885,000 SH   OTR   3,885,000 0 0
AVISTA CORP COM 05379B107 2,672 62,900 SH   OTR   62,900 0 0
AVROBIO INC COM 05455M100 10,823 650,000 SH   OTR   650,000 0 0
BELLICUM PHARMACEUTICALS INC COM 079481107 2,920 1,000,000 SH   OTR   1,000,000 0 0
BEMIS INC COM 081437105 14,512 316,160 SH   OTR   316,160 0 0
BOOKING HLDGS INC COM 09857L108 285,030 165,482 SH   OTR   165,482 0 0
BROOKFIELD PPTY PARTNERS L P UNIT LTD PARTN G16249107 33,449 2,075,000 SH   OTR   2,075,000 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 307,905 1,080,481 SH   OTR   1,080,481 0 0
CHEMOCENTRYX INC COM 16383L106 15,820 1,450,000 SH   OTR   1,450,000 0 0
CIGNA CORP NEW COM 125523100 200,366 1,055,000 SH   OTR   1,055,000 0 0
CITRIX SYS INC COM 177376100 150,435 1,468,234 SH   OTR   1,468,234 0 0
CLOVIS ONCOLOGY INC COM 189464100 17,960 1,000,000 SH   OTR   1,000,000 0 0
CLOVIS ONCOLOGY INC NOTE 1.250% 5/0 189464AC4 10,475 14,750,000 PRN   OTR   14,750,000 0 0
CODEXIS INC COM 192005106 19,289 1,155,000 SH   OTR   1,155,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 2,860 95,365 SH   OTR   95,365 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 35,713 1,250,000 SH   OTR   1,250,000 0 0
CVS HEALTH CORP COM 126650100 60,934 930,000 SH   OTR   930,000 0 0
DELL TECHNOLOGIES INC CL C 24703L202 174,567 3,572,062 SH   OTR   3,572,062 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 18,300 2,000,000 SH   OTR   2,000,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 65,518 925,000 SH   OTR   925,000 0 0
EQUIFAX INC COM 294429105 199,819 2,145,594 SH   OTR   2,145,594 0 0
EQUINIX INC COM PAR $0.001 29444U700 391,656 1,110,892 SH   OTR   1,110,892 0 0
EXELIXIS INC COM 30161Q104 39,340 2,000,000 SH   OTR   2,000,000 0 0
FACEBOOK INC CL A 30303M102 399,975 3,051,148 SH   OTR   3,051,148 0 0
FATE THERAPEUTICS INC COM 31189P102 28,226 2,200,000 SH   OTR   2,200,000 0 0
FIBROGEN INC COM 31572Q808 34,710 750,000 SH   OTR   750,000 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 194,779 1,899,355 SH   OTR   1,899,355 0 0
GENERAL DYNAMICS CORP COM 369550108 255,967 1,628,186 SH   OTR   1,628,186 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 59,523 1,450,000 SH   OTR   1,450,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 43,717 2,381,119 SH   OTR 1 2,381,119 0 0
IHS MARKIT LTD SHS G47567105 283,983 5,920,016 SH   OTR   5,920,016 0 0
INDUSTRIAL LOGISTICS PPTYS T COM SHS BEN INT 456237106 12,009 610,545 SH   OTR   610,545 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 2,848 250,000 SH   OTR   250,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 50,666 5,725,000 SH   OTR   5,725,000 0 0
IQVIA HLDGS INC COM 46266C105 373,987 3,219,308 SH   OTR   3,219,308 0 0
LIBERTY GLOBAL PLC SHS CL A G5480U104 127,452 5,972,437 SH   OTR   5,972,437 0 0
LIBERTY GLOBAL PLC SHS CL C G5480U120 101,904 4,937,202 SH   OTR   4,937,202 0 0
MELLANOX TECHNOLOGIES LTD SHS M51363113 8,776 95,000 SH   OTR   95,000 0 0
MICROSOFT CORP COM 594918104 262,952 2,588,874 SH   OTR   2,588,874 0 0
MIRATI THERAPEUTICS INC COM 60468T105 55,146 1,300,000 SH   OTR   1,300,000 0 0
MYOKARDIA INC COM 62857M105 78,190 1,600,278 SH   OTR   1,600,278 0 0
NOVOCURE LTD ORD SHS G6674U108 41,850 1,250,000 SH   OTR   1,250,000 0 0
NXP SEMICONDUCTORS N V COM N6596X109 39,205 535,000 SH   OTR   535,000 0 0
ORBOTECH LTD ORD M75253100 30,290 535,721 SH   OTR   535,721 0 0
PANDORA MEDIA INC COM 698354107 74,468 9,205,000 SH   OTR   9,205,000 0 0
PFENEX INC COM 717071104 1,914 600,000 SH   OTR   600,000 0 0
PLAYA HOTELS & RESORTS NV SHS N70544106 220,064 30,606,930 SH   OTR   30,606,930 0 0
PRINCIPIA BIOPHARMA INC COM 74257L108 9,587 350,000 SH   OTR   350,000 0 0
PROGENICS PHARMACEUTICALS IN COM 743187106 17,643 4,200,820 SH   OTR   4,200,820 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 14,804 2,199,674 SH   OTR   2,199,674 0 0
PTC THERAPEUTICS INC COM 69366J200 24,024 700,000 SH   OTR   700,000 0 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 23,602 24,130,000 PRN   OTR   24,130,000 0 0
QUOTIENT LTD SHS G73268107 14,688 2,400,000 SH   OTR   2,400,000 0 0
RA MED SYS INC COM 74933X104 305 38,313 SH   OTR   38,313 0 0
RADIUS HEALTH INC COM NEW 750469207 33,692 2,043,149 SH   OTR   2,043,149 0 0
READY CAP CORP COM 75574U101 30,471 2,203,239 SH   OTR   2,203,239 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 39,270 700,000 SH   OTR   700,000 0 0
SAGE THERAPEUTICS INC COM 78667J108 38,316 400,000 SH   OTR   400,000 0 0
SANOFI RIGHT 12/31/2020 80105N113 3,277 6,827,805 SH   OTR   6,827,805 0 0
SAREPTA THERAPEUTICS INC COM 803607100 69,843 640,000 SH   OTR   640,000 0 0
SAVARA INC COM 805111101 18,357 2,425,000 SH   OTR   2,425,000 0 0
SHIRE PLC SPONSORED ADR 82481R106 15,204 87,000 SH   OTR   87,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 1,873,150 7,495,000 SH Call OTR   7,495,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 173,195 693,000 SH Put OTR   693,000 0 0
SYNTHORX INC COM 87167A103 6,710 386,092 SH   OTR   386,092 0 0
TESARO INC COM 881569107 126,225 1,700,000 SH   OTR   1,700,000 0 0
TILRAY INC COM CL 2 88688T100 162,074 2,479,515 SH   OTR   2,479,515 0 0
TRANSLATE BIO INC COM 89374L104 3,750 500,000 SH   OTR   500,000 0 0
TRANSUNION COM 89400J107 299,264 5,268,739 SH   OTR   5,268,739 0 0
TYME TECHNOLOGIES INC COM 90238J103 1,110 300,857 SH   OTR   300,857 0 0
VANECK VECTORS ETF TR SEMICONDUCTOR ET 92189F676 187,652 2,150,000 SH Put OTR   2,150,000 0 0
VERISK ANALYTICS INC COM 92345Y106 157,148 1,441,194 SH   OTR   1,441,194 0 0
VISA INC COM CL A 92826C839 306,065 2,319,726 SH   OTR   2,319,726 0 0
VOYA FINL INC COM 929089100 7,426 185,000 SH   OTR   185,000 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 8,546 909,158 SH   OTR   909,158 0 0
WABTEC CORP COM 929740108 388,557 5,531,059 SH   OTR   5,531,059 0 0
ZAFGEN INC COM 98885E103 8,786 1,775,000 SH   OTR   1,775,000 0 0
ZEALAND PHARMA A S SPONSORED ADR 98920Y304 10,449 900,000 SH   OTR   900,000 0 0
ZOGENIX INC COM NEW 98978L204 74,761 2,050,500 SH   OTR   2,050,500 0 0
ZYMEWORKS INC COM 98985W102 23,121 1,575,000 SH   OTR   1,575,000 0 0