The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Acer Therapeutics Inc | Common | 00444P108 | 11,651 | 579,051 | SH | SOLE | 579,051 | 0 | 0 | ||
| Aclaris Therapeutics, Inc. | Common | 00461U105 | 12,173 | 1,647,214 | SH | SOLE | 1,647,214 | 0 | 0 | ||
| Agile Therapeutics, Inc. | Common | 00847L100 | 872 | 1,513,975 | SH | SOLE | 1,513,975 | 0 | 0 | ||
| Akari Therapeutics Plc | ADR | 00972G108 | 543 | 345,850 | SH | SOLE | 345,850 | 0 | 0 | ||
| Amyris, Inc | Common | 03236M200 | 18,623 | 5,575,785 | SH | SOLE | 5,575,785 | 0 | 0 | ||
| Apellis Pharmaceuticals, Inc. | Common | 03753U106 | 11,536 | 874,573 | SH | SOLE | 874,573 | 0 | 0 | ||
| Arrowhead Pharmaceuticals Inc | Common | 04280A100 | 28,920 | 2,328,475 | SH | SOLE | 2,328,475 | 0 | 0 | ||
| Arvinas Holding Co LLC | Common | 04335A105 | 2,694 | 209,666 | SH | SOLE | 209,666 | 0 | 0 | ||
| Ascendis Pharma A/S | ADR | 04351P101 | 135,752 | 2,166,832 | SH | SOLE | 2,166,832 | 0 | 0 | ||
| Aurinia Pharmaceuticals Inc. | Common | 05156V102 | 8,275 | 1,213,290 | SH | SOLE | 1,213,290 | 0 | 0 | ||
| Biohaven Pharmaceutical Holding Company Ltd | Common | G11196105 | 67,057 | 1,813,340 | SH | SOLE | 1,813,340 | 0 | 0 | ||
| BioPharmX Corporation | Common | 09072X101 | 1,740 | 16,128,515 | SH | SOLE | 16,128,515 | 0 | 0 | ||
| Codexis, Inc | Common | 192005106 | 45,331 | 2,714,458 | SH | SOLE | 2,714,458 | 0 | 0 | ||
| Crinetics Pharmaceuticals Inc | Common | 22663K107 | 113,727 | 3,792,169 | SH | SOLE | 3,792,169 | 0 | 0 | ||
| Cymabay Therapeutics Inc | Common | 23257D103 | 7,130 | 906,000 | SH | SOLE | 906,000 | 0 | 0 | ||
| DBV Technologies S.A. | ADR | 23306J101 | 1,733 | 269,995 | SH | SOLE | 269,995 | 0 | 0 | ||
| Eiger BioPharmaceuticals Inc | Common | 28249U105 | 18,199 | 1,791,257 | SH | SOLE | 1,791,257 | 0 | 0 | ||
| Foamix Pharmaceuticals Ltd. | SHS | M46135105 | 723 | 201,478 | SH | SOLE | 201,478 | 0 | 0 | ||
| Galmed Pharmaceuticals Ltd | SHS | M47238106 | 6,634 | 971,337 | SH | SOLE | 971,337 | 0 | 0 | ||
| Genocea Biosciences Inc | Common | 372427104 | 2,346 | 8,180,000 | SH | SOLE | 8,180,000 | 0 | 0 | ||
| Homology Medicines, Inc. | Common | 438083107 | 25,932 | 1,159,742 | SH | SOLE | 1,159,742 | 0 | 0 | ||
| Iovance Biotherapeutics, Inc. | Common | 462260100 | 14,160 | 1,600,000 | SH | SOLE | 1,600,000 | 0 | 0 | ||
| Kadmon Holdings Inc | Common | 48283N106 | 21,745 | 10,454,545 | SH | SOLE | 10,454,545 | 0 | 0 | ||
| Kala Pharmaceuticals, Inc. | Common | 483119103 | 5,100 | 1,043,020 | SH | SOLE | 1,043,020 | 0 | 0 | ||
| KalVista Pharmaceuticals Inc. | Common | 483497103 | 26,843 | 1,359,149 | SH | SOLE | 1,359,149 | 0 | 0 | ||
| Kiniksa Pharmaceuticals | Common | G5269C101 | 7,440 | 264,878 | SH | SOLE | 264,878 | 0 | 0 | ||
| MEI Pharma Inc | Common | 55279B202 | 15,254 | 5,778,106 | SH | SOLE | 5,778,106 | 0 | 0 | ||
| Menlo Therapeutics Inc. | Common | 586858102 | 16,526 | 4,011,236 | SH | SOLE | 4,011,236 | 0 | 0 | ||
| Mirati Therapeutics Inc. | Common | 60468T105 | 10,652 | 251,107 | SH | SOLE | 251,107 | 0 | 0 | ||
| Nabriva Therapeutics AG | SHS | G63637105 | 9,664 | 6,619,190 | SH | SOLE | 6,619,190 | 0 | 0 | ||
| Obseva SA | Common | H5861P103 | 11,864 | 937,147 | SH | SOLE | 937,147 | 0 | 0 | ||
| Orchard Therapeutics plc | ADS | 68570P101 | 12,771 | 811,894 | SH | SOLE | 811,894 | 0 | 0 | ||
| Selecta Biosciences Inc | Common | 816212104 | 1,453 | 546,054 | SH | SOLE | 546,054 | 0 | 0 | ||
| Sierra Oncology, Inc | Common | 82640U107 | 3,219 | 2,438,270 | SH | SOLE | 2,438,270 | 0 | 0 | ||
| Sinovac Biotech Ltd. | SHS | P8696W104 | 40,946 | 5,900,000 | SH | SOLE | 5,900,000 | 0 | 0 | ||
| Soleno Therapeutics, Inc. | Common | 834203200 | 7,455 | 4,359,683 | SH | SOLE | 4,359,683 | 0 | 0 | ||
| Soleno Therapeutics, Inc. | Warrant | 834203135 | 19 | 188,772 | SH | SOLE | 188,772 | 0 | 0 | ||
| Sunesis Pharmaceuticals, Inc. | Common PAR | 867328700 | 81 | 195,474 | SH | SOLE | 195,474 | 0 | 0 | ||
| Trevena, Inc. | Common | 89532E109 | 743 | 1,728,000 | SH | SOLE | 1,728,000 | 0 | 0 | ||
| Tricida, Inc. | Common | 89610F101 | 18,413 | 781,185 | SH | SOLE | 781,185 | 0 | 0 | ||
| Verona Pharma PLC | ADS | 925050106 | 13,437 | 1,492,951 | SH | SOLE | 1,492,951 | 0 | 0 | ||
| Xenon Pharmaceuticals Inc | Common | 98420N105 | 8,869 | 1,405,476 | SH | SOLE | 1,405,476 | 0 | 0 | ||
| Zai Lab Limited | ADR | 98887Q104 | 1,900 | 81,819 | SH | SOLE | 81,819 | 0 | 0 | ||
| Zogenix, Inc. | Common | 98978L204 | 3,828 | 105,000 | SH | SOLE | 105,000 | 0 | 0 | ||
| Zymeworks Inc | Common | 98985W102 | 9,104 | 620,134 | SH | SOLE | 620,134 | 0 | 0 | ||