The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101 21,176 100,500 SH Put DFND 1 100,500 0 0
ACER THERAPEUTICS INC COM 00444P108 597 19,367 SH   DFND 1 19,367 0 0
ADAMIS PHARMACEUTICALS CORP COM NEW 00547W208 2,975 850,000 SH   DFND 1 850,000 0 0
ADECOAGRO S A COM L00849106 2,573 350,000 SH   DFND 1 350,000 0 0
ADIENT PLC ORD SHS G0084W101 39,310 1,000,000 SH   DFND 1 1,000,000 0 0
ADMA BIOLOGICS INC COM 000899104 4,999 805,000 SH   DFND 1 805,000 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 173 28,544 SH   DFND 1 28,544 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 18,630 1,350,000 SH   DFND 1 1,350,000 0 0
ALLEGRO MERGER CORP *W EXP 01/06/202 01749N111 155 443,772 SH   DFND 1 443,772 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 26,256 300,000 SH   DFND 1 300,000 0 0
ALTRIA GROUP INC COM 02209S103 6,031 100,000 SH Put DFND 1 100,000 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 1,460 200,000 SH   DFND 1 200,000 0 0
ARDELYX INC COM 039697107 2,828 650,000 SH   DFND 1 650,000 0 0
AVEO PHARMACEUTICALS INC COM 053588109 8,109 2,449,800 SH   DFND 1 2,449,800 0 0
AZURRX BIOPHARMA INC COM 05502L105 1,028 400,000 SH   DFND 1 400,000 0 0
BIG ROCK PARTNERS ACQUISI CO RIGHT 12/01/2022 089482129 83 165,000 SH   DFND 1 165,000 0 0
BIG ROCK PARTNERS ACQUISI CO *W EXP 12/01/202 089482111 37 82,500 SH   DFND 1 82,500 0 0
BISON CAP ACQUISITION CORP RIGHT 03/20/2019 G1142P138 53 100,000 SH   DFND 1 100,000 0 0
BISON CAP ACQUISITION CORP *W EXP 06/20/202 G1142P112 26 50,000 SH   DFND 1 50,000 0 0
BLACK RIDGE ACQUISITION CORP RIGHT 07/10/2019 09216T123 74 200,000 SH   DFND 1 200,000 0 0
BLACK RIDGE ACQUISITION CORP *W EXP 07/10/202 09216T115 315 700,000 SH   DFND 1 700,000 0 0
BLACKSTONE GROUP L P COM UNIT LTD 09253U108 6,474 170,000 SH   DFND 1 170,000 0 0
CARVANA CO CL A 146869102 92,277 1,561,634 SH   DFND 1 1,561,634 0 0
CATERPILLAR INC DEL COM 149123101 11,437 75,000 SH Put DFND 1 75,000 0 0
CM SEVEN STAR ACQUISITION CO RIGHT 08/21/2022 G2345N136 96 175,000 SH   DFND 1 175,000 0 0
CM SEVEN STAR ACQUISITION CO *W EXP 08/21/202 G2345N110 44 87,500 SH   DFND 1 87,500 0 0
COCA COLA CO COM 191216100 18,476 400,000 SH Put DFND 1 400,000 0 0
CONSTELLATION ALPHA CAP CORP RIGHT 99/99/9999 G2379F132 72 180,000 SH   DFND 1 180,000 0 0
CONSTELLATION ALPHA CAP CORP *W EXP 03/23/202 G2379F116 84 380,000 SH   DFND 1 380,000 0 0
CONTRAFECT CORP COM 212326102 4,720 2,280,000 SH   DFND 1 2,280,000 0 0
CRESUD S A C I F Y A SPONSORED ADR 226406106 11,672 824,314 SH   DFND 1 824,314 0 0
DHT HOLDINGS INC SHS NEW Y2065G121 1,622 345,000 SH   DFND 1 345,000 0 0
DIANA SHIPPING INC COM Y2066G104 1,806 438,364 SH   DFND 1 438,364 0 0
DRAPER OAKWOOD TECHNOLOGY *W EXP 09/19/202 26146L111 50 85,200 SH   DFND 1 85,200 0 0
EASTERLY ACQUISITION CORP *W EXP 07/29/202 27616L110 550 500,000 SH   DFND 1 500,000 0 0
EDISON INTL COM 281020107 8,122 120,000 SH   DFND 1 120,000 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 7,575 631,233 SH   DFND 1 631,233 0 0
ELLIE MAE INC COM 28849P100 2,369 25,000 SH Put DFND 1 25,000 0 0
ENERGY RECOVERY INC COM 29270J100 9,845 1,100,000 SH   DFND 1 1,100,000 0 0
ENOVA INTL INC COM 29357K103 13,392 465,000 SH   DFND 1 465,000 0 0
ESTRE AMBIENTAL INC *W EXP 12/21/202 G3206V118 262 750,000 SH   DFND 1 750,000 0 0
EVOKE PHARMA INC COM 30049G104 341 114,300 SH   DFND 1 114,300 0 0
EXACT SCIENCES CORP COM 30063P105 7,892 100,000 SH Put DFND 1 100,000 0 0
FACEBOOK INC CL A 30303M102 8,223 50,000 SH Put DFND 1 50,000 0 0
FALCON MINERALS CORP *W EXP 07/21/202 30607B208 255 149,600 SH   DFND 1 149,600 0 0
FATE THERAPEUTICS INC COM 31189P102 10,585 649,800 SH   DFND 1 649,800 0 0
FENNEC PHARMACEUTICALS INC COM 31447P100 7,965 971,351 SH   DFND 1 971,351 0 0
FERRARI N V COM N3167Y103 27,382 200,000 SH Put DFND 1 200,000 0 0
FORUM MERGER II CORP UNIT 09/30/2025 34986F202 3,039 300,000 SH   DFND 1 300,000 0 0
GALMED PHARMACEUTICALS LTD SHS M47238106 18,333 1,350,000 SH   DFND 1 1,350,000 0 0
GENCO SHIPPING & TRADING LTD SHS Y2685T131 955 68,200 SH   DFND 1 68,200 0 0
GIGCAPITAL INC RIGHT 03/06/2020 37518N114 106 200,000 SH   DFND 1 200,000 0 0
GIGCAPITAL INC *W EXP 06/08/202 37518N122 75 150,000 SH   DFND 1 150,000 0 0
GLOBALSTAR INC COM 378973408 2,032 4,000,000 SH   DFND 1 4,000,000 0 0
GORDON POINTE ACQUISITION CO *W EXP 07/30/202 382788115 146 225,000 SH   DFND 1 225,000 0 0
GREENLAND ACQUISITIN CORPORA RIGHT 04/27/2025 G40981113 54 150,000 SH   DFND 1 150,000 0 0
GREIF INC CL B 397624206 687 11,910 SH   DFND 1 11,910 0 0
GRUBHUB INC COM 400110102 13,862 100,000 SH Put DFND 1 100,000 0 0
GRUPO FINANCIERO GALICIA S A SP ADR 10 SH B 399909100 2,670 105,000 SH   DFND 1 105,000 0 0
HAYMAKER ACQUISITION CORP *W EXP 10/27/202 420870115 390 300,000 SH   DFND 1 300,000 0 0
HENNESSY CAP ACQUSTON CORP I *W EXP 06/15/202 42588L113 806 537,500 SH   DFND 1 537,500 0 0
HERBALIFE NUTRITION LTD COM SHS G4412G101 16,365 300,000 SH Put DFND 1 300,000 0 0
HL ACQUISITIONS CORP RIGHT 07/17/2023 G4603R130 72 180,000 SH   DFND 1 180,000 0 0
HL ACQUISITIONS CORP *W EXP 06/21/202 G4603R122 65 180,000 SH   DFND 1 180,000 0 0
HOSTESS BRANDS INC *W EXP 11/04/202 44109J114 2,839 2,680,000 SH   DFND 1 2,680,000 0 0
I AM CAP ACQUISITION CO RIGHT 05/22/2019 45074Q124 100 200,000 SH   DFND 1 200,000 0 0
I AM CAP ACQUISITION CO *W EXP 05/22/202 45074Q116 245 700,000 SH   DFND 1 700,000 0 0
IFRESH INC COM 449538107 56 25,000 SH   DFND 1 25,000 0 0
INDUSTREA ACQUISITION CORP *W EXP 08/01/202 45579J112 1,235 1,234,606 SH   DFND 1 1,234,606 0 0
INSPIRED ENTMT INC COM 45782N108 4,626 758,430 SH   DFND 1 758,430 0 0
INTEC PHARMA LTD JERUSALEM SHS M53644106 848 150,000 SH   DFND 1 150,000 0 0
INTERNATIONAL BUSINESS MACHS COM 459200101 15,121 100,000 SH Put DFND 1 100,000 0 0
IRSA INVERSIONES Y REP S A GLOBL DEP RCPT 450047204 14,256 841,071 SH   DFND 1 841,071 0 0
IRSA PROPIEDADES COMERCIALES SPONSORED ADR 463588103 973 40,747 SH   DFND 1 40,747 0 0
JOHNSON & JOHNSON COM 478160104 34,543 250,000 SH Put DFND 1 250,000 0 0
KELLOGG CO COM 487836108 14,004 200,000 SH Put DFND 1 200,000 0 0
KROGER CO COM 501044101 16,738 575,000 SH   DFND 1 575,000 0 0
KROGER CO COM 501044101 11,644 400,000 SH Call DFND 1 400,000 0 0
LEAP THERAPEUTICS INC COM 52187K101 1,169 150,000 SH   DFND 1 150,000 0 0
LEGACY ACQUISITION CORP *W EXP 11/30/202 524643111 223 500,000 SH   DFND 1 500,000 0 0
LEISURE ACQUISITION CORP *W EXP 12/05/201 52539T115 134 125,000 SH   DFND 1 125,000 0 0
LF CAP ACQUISITION CORP *W EXP 06/22/202 50200K116 248 450,000 SH   DFND 1 450,000 0 0
LIBERTY TRIPADVISOR HLDGS IN COM SER A 531465102 371 25,000 SH   DFND 1 25,000 0 0
M D C HLDGS INC COM 552676108 2,958 100,000 SH Put DFND 1 100,000 0 0
MACROGENICS INC COM 556099109 7,196 335,634 SH   DFND 1 335,634 0 0
MAGNOLIA OIL & GAS CORP *W EXP 07/31/202 559663117 1,597 341,333 SH   DFND 1 341,333 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 11,000 1,100,000 SH   DFND 1 1,100,000 0 0
MATLIN & PARTNERS ACQUISITIO *W EXP 05/28/202 57682V114 600 800,000 SH   DFND 1 800,000 0 0
MEDICINES CO COM 584688105 5,003 167,252 SH   DFND 1 167,252 0 0
MEGALITH FINL ACQUISITION CO UNIT 09/30/2025 58518F208 4,040 400,000 SH   DFND 1 400,000 0 0
MEIRAGTX HOLDINGS PLC COM G59665102 952 70,000 SH   DFND 1 70,000 0 0
MICRON TECHNOLOGY INC COM 595112103 12,664 280,000 SH   DFND 1 280,000 0 0
MIRAGEN THERAPEUTICS INC COM 60463E111 2,790 500,000 SH   DFND 1 500,000 0 0
MODERN MEDIA ACQUISITION RIGHT 99/99/9999 60765P129 470 1,000,000 SH   DFND 1 1,000,000 0 0
MODERN MEDIA ACQUISITION *W EXP 05/17/202 60765P111 300 500,000 SH   DFND 1 500,000 0 0
MONDELEZ INTL INC CL A 609207105 4,996 100,000 SH Put DFND 1 100,000 0 0
MTECH ACQUISITION CORP *W EXP 08/01/202 55378W115 111 75,000 SH   DFND 1 75,000 0 0
MUDRICK CAP ACQUISITION CORP *W EXP 02/12/202 624745113 1,750 2,500,000 SH   DFND 1 2,500,000 0 0
MYRIAD GENETICS INC COM 62855J104 4,600 100,000 SH Put DFND 1 100,000 0 0
NATIONAL ENERGY SERVICES REU *W EXP 05/05/202 G6375R115 1,624 725,000 SH   DFND 1 725,000 0 0
NATIONAL OILWELL VARCO INC COM 637071101 12,709 295,000 SH   DFND 1 295,000 0 0
NAVIOS MARITIME HLDGS INC COM Y62196103 213 300,000 SH   DFND 1 300,000 0 0
NETFLIX INC COM 64110L106 74,826 200,000 SH Put DFND 1 200,000 0 0
NEW FRONTIER CORP *W EXP 99/99/999 G6485P124 59 50,000 SH   DFND 1 50,000 0 0
NEW YORK REIT INC COM NEW 64976L208 15,535 856,394 SH   DFND 1 856,394 0 0
NEXEO SOLUTIONS INC *W EXP 06/09/202 65342H110 1,463 1,423,900 SH   DFND 1 1,423,900 0 0
NII HOLDINGS INC COM PAR 62913F508 82,307 14,045,499 SH   DFND 1 14,045,499 0 0
NORDIC AMERICAN TANKERS LIMI COM G65773106 575 275,000 SH   DFND 1 275,000 0 0
NVIDIA CORP COM 67066G104 14,051 50,000 SH Put DFND 1 50,000 0 0
ON DECK CAP INC COM 682163100 23,089 3,050,000 SH   DFND 1 3,050,000 0 0
ONCONOVA THERAPEUTICS INC COM PAR 68232V405 7,097 966,877 SH   DFND 1 966,877 0 0
ONCONOVA THERAPEUTICS INC *W EXP 07/11/202 68232V116 1,373 922,550 SH   DFND 1 922,550 0 0
ONCOSEC MED INC COM NEW 68234L207 420 300,000 SH   DFND 1 300,000 0 0
ONE MADISON CORP *W EXP 99/99/999 G6772P126 145 125,000 SH   DFND 1 125,000 0 0
OPES ACQUISITION CORP *W EXP 03/13/202 68373P118 60 150,000 SH   DFND 1 150,000 0 0
ORACLE CORP COM 68389X105 10,312 200,000 SH Put DFND 1 200,000 0 0
OTONOMY INC COM 68906L105 2,200 800,000 SH   DFND 1 800,000 0 0
PENSARE ACQUISITION CORP RIGHT 99/99/9999 70957E125 272 605,000 SH   DFND 1 605,000 0 0
PENSARE ACQUISITION CORP *W EXP 07/27/202 70957E117 60 115,000 SH   DFND 1 115,000 0 0
PG&E CORP COM 69331C108 23,553 511,910 SH   DFND 1 511,910 0 0
POLARITYTE INC COM 731094108 3,113 163,000 SH   DFND 1 163,000 0 0
REDHILL BIOPHARMA LTD SPONSORED ADS 757468103 32,062 3,631,019 SH   DFND 1 3,631,019 0 0
SCORPIO TANKERS INC SHS Y7542C106 5,563 2,767,440 SH   DFND 1 2,767,440 0 0
SELECT SECTOR SPDR TR SBI CONS STPLS 81369Y308 24,269 450,000 SH Put DFND 1 450,000 0 0
SELLAS LIFE SCIENCES GROUP I COM 81642T100 1,556 1,275,000 SH   DFND 1 1,275,000 0 0
SEQUENTIAL BRNDS GROUP INC N COM 81734P107 5,605 3,356,200 SH   DFND 1 3,356,200 0 0
SIERRA ONCOLOGY INC COM 82640U107 3,060 1,800,000 SH   DFND 1 1,800,000 0 0
SOLENO THERAPEUTICS INC COM NEW 834203200 1,823 844,112 SH   DFND 1 844,112 0 0
SPDR SERIES TRUST S&P REGL BKG 78464A698 2,971 50,000 SH Put DFND 1 50,000 0 0
SPDR SERIES TRUST S&P RETAIL ETF 78464A714 17,857 350,000 SH Put DFND 1 350,000 0 0
STRONGBRIDGE BIOPHARMA PLC SHS USD G85347105 1,454 299,700 SH   DFND 1 299,700 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 4,210 521,000 SH   DFND 1 521,000 0 0
SYNTHETIC BIOLOGICS INC COM NEW 87164U201 111 42,858 SH   DFND 1 42,858 0 0
TAPIMMUNE INC COM PAR 876033408 905 100,000 SH   DFND 1 100,000 0 0
TARGET CORP COM 87612E110 4,411 50,000 SH Put DFND 1 50,000 0 0
TENZING ACQUISITION CORP UNIT 08/24/2024 G8708A124 2,013 200,000 SH   DFND 1 200,000 0 0
TESLA INC COM 88160R101 358,763 1,355,000 SH Put DFND 1 1,355,000 0 0
TETRAPHASE PHARMACEUTICALS I COM 88165N105 1,974 715,097 SH   DFND 1 715,097 0 0
TG THERAPEUTICS INC COM 88322Q108 2,800 500,000 SH   DFND 1 500,000 0 0
TIBERIUS ACQUISITION CORP *W EXP 02/28/202 88633A115 266 450,000 SH   DFND 1 450,000 0 0
TKK SYMPHONY ACQUISITION COR ORD SHS G88950103 2,138 225,000 SH   DFND 1 225,000 0 0
TKK SYMPHONY ACQUISITION COR RIGHT 02/20/2020 G88950137 102 225,000 SH   DFND 1 225,000 0 0
TKK SYMPHONY ACQUISITION COR *W EXP 02/20/202 G88950129 54 225,000 SH   DFND 1 225,000 0 0
TOCAGEN INC COM 888846102 780 50,000 SH   DFND 1 50,000 0 0
TOTTENHAM ACQUISITION I LTD RIGHT 06/05/2020 G8959N122 50 134,000 SH   DFND 1 134,000 0 0
TOTTENHAM ACQUISITION I LTD *W EXP 05/06/202 G8959N114 108 542,000 SH   DFND 1 542,000 0 0
TRACON PHARMACEUTICALS INC COM 89237H100 5,615 2,738,938 SH   DFND 1 2,738,938 0 0
TRIDENT ACQUISITIONS CORP *W EXP 05/09/202 89615T114 578 1,993,750 SH   DFND 1 1,993,750 0 0
TRINITY MERGER CORP *W EXP 05/11/202 89653L114 350 700,000 SH   DFND 1 700,000 0 0
TRIVAGO N V SPON ADS A SHS 89686D105 34,496 5,600,000 SH   DFND 1 5,600,000 0 0
TRUECAR INC COM 89785L107 47,705 3,383,358 SH   DFND 1 3,383,358 0 0
TWELVE SEAS INVESTMENT COMPA RIGHT 12/22/2019 G9145A131 74 175,000 SH   DFND 1 175,000 0 0
TWELVE SEAS INVESTMENT COMPA *W EXP 12/22/202 G9145A115 209 581,850 SH   DFND 1 581,850 0 0
UNION ACQUISITION CORP RIGHT 12/02/2019 G9366W135 80 200,000 SH   DFND 1 200,000 0 0
UNION ACQUISITION CORP *W EXP 07/01/202 G9366W127 70 200,000 SH   DFND 1 200,000 0 0
UNIQURE NV SHS N90064101 35,811 984,100 SH   DFND 1 984,100 0 0
VECTOIQ ACQUISITION CORP *W EXP 05/11/202 92243N111 305 500,000 SH   DFND 1 500,000 0 0
WALMART INC COM 931142103 9,391 100,000 SH Put DFND 1 100,000 0 0
WILLSCOT CORP *W EXP 09/10/202 971375118 7,420 2,489,958 SH   DFND 1 2,489,958 0 0
WRIGHT MED GROUP N V RIGHT 03/01/2019 N96617126 555 396,531 SH   DFND 1 396,531 0 0
ZAFGEN INC COM 98885E107 15,197 1,300,000 SH   DFND 1 1,300,000 0 0
ZOGENIX INC COM NEW 98978L204 2,480 50,000 SH   DFND 1 50,000 0 0