The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 105,345 1,840,732 SH   OTR   1,840,732 0 0
AETNA INC NEW COM 00817Y108 1,506,161 7,425,000 SH   OTR   7,425,000 0 0
AKORN INC COM 009728106 909 70,000 SH   OTR   70,000 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 61,455 373,000 SH   OTR   373,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 24,204 276,551 SH   OTR   276,551 0 0
ALPHABET INC CAP STK CL C 02079K107 375,591 314,705 SH   OTR   314,705 0 0
ALTABA INC COM 021346101 1,446,686 21,237,317 SH   OTR   21,237,317 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 53,898 3,312,700 SH   OTR   3,312,700 0 0
ANHEUSER BUSCH INBEV SA/NV SPONSORED ADR 03524A108 25,668 293,109 SH   OTR   293,109 0 0
ANTHEM INC COM 036752103 283,642 1,035,000 SH   OTR   1,035,000 0 0
APTINYX INC COM 03836N103 19,403 670,000 SH   OTR   670,000 0 0
ARQULE INC COM 04269E107 2,830 500,000 SH   OTR   500,000 0 0
ARRAY BIOPHARMA INC COM 04269X105 77,900 5,125,000 SH   OTR   5,125,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 103,264 1,457,297 SH   OTR   1,457,297 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 11,142 300,000 SH   OTR   300,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 135,329 3,420,000 SH   OTR   3,420,000 0 0
AVISTA CORP COM 05379B107 74,323 1,470,000 SH   OTR   1,470,000 0 0
AVROBIO INC COM 05455M100 24,120 465,000 SH   OTR   465,000 0 0
BELLICUM PHARMACEUTICALS INC COM 079481107 13,162 2,136,629 SH   OTR   2,136,629 0 0
BEMIS INC COM 081437105 10,044 206,660 SH   OTR   206,660 0 0
BOOKING HLDGS INC COM 09857L108 254,488 128,270 SH   OTR   128,270 0 0
BROOKFIELD PPTY PARTNERS L P UNIT LTD PARTN G16249107 16,595 794,382 SH   OTR   794,382 0 0
BROOKFIELD PROPERTY REIT INC CL A 11282X103 168,575 8,054,215 SH   OTR   8,054,215 0 0
CA INC COM 12673P105 61,031 1,382,361 SH   OTR   1,382,361 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 385,510 1,182,980 SH   OTR   1,182,980 0 0
CHEMOCENTRYX INC COM 16383L106 14,536 1,150,000 SH   OTR   1,150,000 0 0
CITRIX SYS INC COM 177376100 201,516 1,812,849 SH   OTR   1,812,849 0 0
CODEXIS INC COM 192005106 17,150 1,000,000 SH   OTR   1,000,000 0 0
COHERUS BIOSCIENCES INC COM 19249H103 11,550 700,000 SH   OTR   700,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 4,063 141,815 SH   OTR   141,815 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 45,175 1,018,594 SH   OTR   1,018,594 0 0
DELL TECHNOLOGIES INC COM CL V 24703L103 620,500 6,389,000 SH   OTR   6,389,000 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 13,268 1,070,000 SH   OTR   1,070,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 74,137 867,500 SH   OTR   867,500 0 0
ENDOCYTE INC COM 29269A102 7,104 400,000 SH   OTR   400,000 0 0
ENVISION HEALTHCARE CORP COM 29414D100 256,774 5,615,000 SH   OTR   5,615,000 0 0
EQUIFAX INC COM 294429105 106,521 815,817 SH   OTR   815,817 0 0
EQUINIX INC COM PAR $0.001 29444U700 263,457 608,600 SH   OTR   608,600 0 0
EXELIXIS INC COM 30161Q104 19,138 1,080,000 SH   OTR   1,080,000 0 0
EXPRESS SCRIPTS HLDG CO COM 30219G108 1,130,144 11,895,000 SH   OTR   11,895,000 0 0
FACEBOOK INC CL A 30303M102 408,838 2,485,943 SH   OTR   2,485,943 0 0
FATE THERAPEUTICS INC COM 31189P102 8,634 530,000 SH   OTR   530,000 0 0
FIBROGEN INC COM 31572Q808 84,746 1,395,000 SH   OTR   1,395,000 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 213,995 1,961,994 SH   OTR   1,961,994 0 0
GENERAL DYNAMICS CORP COM 369550108 362,502 1,770,722 SH   OTR   1,770,722 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 52,060 1,370,000 SH   OTR   1,370,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 38,252 1,790,000 SH   OTR 1 1,790,000 0 0
IHS MARKIT LTD SHS G47567105 272,781 5,055,245 SH   OTR   5,055,245 0 0
INTEGRATED DEVICE TECHNOLOGY COM 458118106 30,086 640,000 SH   OTR   640,000 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 15,741 550,000 SH   OTR   550,000 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 5,425 250,000 SH   OTR   250,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 53,156 4,725,000 SH   OTR   4,725,000 0 0
IQVIA HLDGS INC COM 46266C105 394,330 3,039,386 SH   OTR   3,039,386 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 4,422 200,000 SH   OTR   200,000 0 0
LIBERTY GLOBAL PLC SHS CL A G5480U104 191,794 6,629,602 SH   OTR   6,629,602 0 0
LIBERTY GLOBAL PLC SHS CL C G5480U120 196,885 6,991,640 SH   OTR   6,991,640 0 0
MICROSOFT CORP COM 594918104 246,949 2,159,213 SH   OTR   2,159,213 0 0
MIRATI THERAPEUTICS INC COM 60468T105 41,213 875,000 SH   OTR   875,000 0 0
MYOKARDIA INC COM 62857M105 99,839 1,531,278 SH   OTR   1,531,278 0 0
NOVOCURE LTD ORD SHS G6674U108 70,740 1,350,000 SH   OTR   1,350,000 0 0
NXP SEMICONDUCTORS N V COM N6596X109 141,075 1,650,000 SH   OTR   1,650,000 0 0
ORBOTECH LTD ORD M75253100 13,671 230,000 SH   OTR   230,000 0 0
PFENEX INC COM 717071104 3,066 600,000 SH   OTR   600,000 0 0
PLAYA HOTELS & RESORTS NV SHS N70544106 294,745 30,606,930 SH   OTR   30,606,930 0 0
PRINCIPIA BIOPHARMA INC COM 74257L108 3,653 125,000 SH   OTR   125,000 0 0
PROGENICS PHARMACEUTICALS IN COM 743187106 22,652 3,612,820 SH   OTR   3,612,820 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 23,083 2,243,202 SH   OTR   2,243,202 0 0
PTC THERAPEUTICS INC COM 69366J200 19,740 420,000 SH   OTR   420,000 0 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 21,114 18,350,000 PRN   OTR   18,350,000 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 18,799 410,000 SH   OTR   410,000 0 0
RA MED SYS INC COM 74933X104 2,730 150,000 SH   OTR   150,000 0 0
RADIUS HEALTH INC COM NEW 750469207 36,368 2,043,149 SH   OTR   2,043,149 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 55,065 673,500 SH   OTR   673,500 0 0
ROCKWELL COLLINS INC COM 774341101 583,653 4,155,000 SH   OTR   4,155,000 0 0
SAGE THERAPEUTICS INC COM 78667J108 88,281 625,000 SH   OTR   625,000 0 0
SANOFI RIGHT 12/31/2020 80105N113 3,823 6,827,805 SH   OTR   6,827,805 0 0
SAREPTA THERAPEUTICS INC COM 803607100 31,494 195,000 SH   OTR   195,000 0 0
SAVARA INC COM 805111101 26,985 2,418,009 SH   OTR   2,418,009 0 0
SHIRE PLC SPONSORED ADR 82481R106 15,770 87,000 SH   OTR   87,000 0 0
SINA CORP ORD G81477104 78,111 1,124,224 SH   OTR   1,124,224 0 0
SOLARCITY CORP NOTE 2.750%11/0 83416TAA8 4,932 5,000,000 PRN   OTR   5,000,000 0 0
SOLID BIOSCIENCES INC COM 83422E105 13,918 295,000 SH   OTR   295,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 2,700,934 9,290,500 SH Put OTR   9,290,500 0 0
SPECTRUM PHARMACEUTICALS INC COM 84763A108 4,200 250,000 SH   OTR   250,000 0 0
SUTHERLAND ASSET MGMT CORP M COM 86933G105 36,684 2,203,239 SH   OTR   2,203,239 0 0
SUTRO BIOPHARMA INC COM 869367102 2,250 150,000 SH   OTR   150,000 0 0
TILRAY INC COM CL 2 88688T100 285,494 2,479,515 SH   OTR   2,479,515 0 0
TRANSLATE BIO INC COM 89374L104 4,500 450,000 SH   OTR   450,000 0 0
TRANSUNION COM 89400J107 252,204 3,427,611 SH   OTR   3,427,611 0 0
TWENTY FIRST CENTY FOX INC CL A 90130A101 66,484 1,435,000 SH   OTR   1,435,000 0 0
TWENTY FIRST CENTY FOX INC CL B 90130A200 245,595 5,360,000 SH   OTR   5,360,000 0 0
TYME TECHNOLOGIES INC COM 90238J103 1,128 405,857 SH   OTR   405,857 0 0
VERISK ANALYTICS INC COM 92345Y106 171,730 1,424,553 SH   OTR   1,424,553 0 0
VISA INC COM CL A 92826C839 296,156 1,973,191 SH   OTR   1,973,191 0 0
VOYA FINL INC COM 929089100 9,189 185,000 SH   OTR   185,000 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 17,201 909,158 SH   OTR   909,158 0 0
WABTEC CORP COM 929740108 367,143 3,500,600 SH   OTR   3,500,600 0 0
Y MABS THERAPEUTICS INC COM 984241109 3,320 125,000 SH   OTR   125,000 0 0
ZAFGEN INC COM 98885E103 18,996 1,625,000 SH   OTR   1,625,000 0 0
ZEALAND PHARMA A S SPONSORED ADR 98920Y304 14,868 900,000 SH   OTR   900,000 0 0
ZOGENIX INC COM NEW 98978L204 89,057 1,795,500 SH   OTR   1,795,500 0 0
ZYMEWORKS INC COM 98985W102 20,960 1,335,000 SH   OTR   1,335,000 0 0