The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abeona Therapeutics Inc COM 00289Y107 10,029 626,804 SH   SOLE   626,804 0 0
Acorda Therapeutics Inc COM 00484M106 4,259 148,380 SH   SOLE   148,380 0 0
Allergan PLC SHS G0177J108 37,031 222,113 SH   SOLE   222,113 0 0
Akorn Inc COM 009728106 4,471 269,503 SH   SOLE   269,503 0 0
Alexion Pharmaceuticals Inc COM 015351109 16,465 132,623 SH   SOLE   132,623 0 0
Aerpio Pharmaceuticals Inc COM 00810B105 1,240 298,873 SH   SOLE   298,873 0 0
Avrobio Inc COM 05455M100 286 10,000 SH   SOLE   10,000 0 0
AstraZeneca PLC SPONSORED ADR 046353108 18,267 520,279 SH   SOLE   520,279 0 0
BioMarin Pharmaceutical Inc COM 09061G101 28,260 300,000 SH Call SOLE   300,000 0 0
Audentes Therapeutics Inc COM 05070R104 9,228 241,500 SH   SOLE   241,500 0 0
Cara Therapeutics Inc COM 140755109 8,346 435,800 SH   SOLE   435,800 0 0
Cymabay Therapeutics Inc COM 23257D103 11,121 828,655 SH   SOLE   828,655 0 0
Catalyst Biosciences Inc COM NEW 14888D208 9,183 786,865 SH   SOLE   786,865 0 0
Cellectis SA SPONSORED ADS 15117K103 15,509 548,212 SH   SOLE   548,212 0 0
Corcept Therapeutics Inc COM 218352102 5,269 335,177 SH   SOLE   335,177 0 0
Corbus Pharmaceuticals Holding COM 21833P103 678 134,280 SH   SOLE   134,280 0 0
Deciphera Pharmaceuticals Inc COM 24344T101 5,108 129,800 SH   SOLE   129,800 0 0
Dova Pharmaceuticals Inc COM 25985T102 24,545 820,348 SH   SOLE   820,348 0 0
Endocyte Inc COM 29269A102 8,225 596,000 SH   SOLE   596,000 0 0
Esperion Therapeutics Inc COM 29664W105 11,259 287,300 SH   SOLE   287,300 0 0
Exelixis Inc COM 30161Q104 30,593 1,421,600 SH   SOLE   1,421,600 0 0
FibroGen Inc COM 31572Q808 8,487 135,583 SH   SOLE   135,583 0 0
Global Blood Therapeutics Inc COM 37890U108 18,265 404,092 SH   SOLE   404,092 0 0
Immunomedics Inc COM 452907108 31,460 1,329,104 SH   SOLE   1,329,104 0 0
Insmed Inc COM PAR $.01 457669307 15,298 646,863 SH   SOLE   646,863 0 0
Kiniksa Pharmaceuticals Ltd COM CL A G5269C101 680 39,180 SH   SOLE   39,180 0 0
Kura Oncology Inc COM 50127T109 6,943 381,459 SH   SOLE   381,459 0 0
MediWound Ltd ORD SHS M68830104 308 44,576 SH   SOLE   44,576 0 0
Magenta Therapeutics Inc COM 55910K108 2,025 150,000 SH   SOLE   150,000 0 0
Molecular Templates Inc COM 608550109 902 172,384 SH   SOLE   172,384 0 0
Mylan NV SHS EURO N59465109 15,613 432,009 SH   SOLE   432,009 0 0
Neos Therapeutics Inc COM 64052L106 2,369 378,961 SH   SOLE   378,961 0 0
OncoSec Medical Inc COM NEW 68234L207 3,608 2,614,297 SH   SOLE   2,614,297 0 0
Pacira Pharmaceuticals Inc/DE COM 695127100 18,157 566,508 SH   SOLE   566,508 0 0
Sage Therapeutics Inc COM 78667J108 12,378 79,080 SH   SOLE   79,080 0 0
Seattle Genetics Inc COM 812578102 6,784 102,187 SH   SOLE   102,187 0 0
Sangamo Therapeutics Inc COM 800677106 15,150 1,066,914 SH   SOLE   1,066,914 0 0
Sol-Gel Technologies Ltd SHS M8694L103 3,979 515,373 SH   SOLE   515,373 0 0
Stemline Therapeutics Inc COM 85858C107 8,980 559,517 SH   SOLE   559,517 0 0
TG Therapeutics Inc COM 88322Q108 949 72,200 SH   SOLE   72,200 0 0
TG Therapeutics Inc COM 88322Q108 658 50,000 SH Call SOLE   50,000 0 0
TESARO Inc COM 881569107 19,278 433,500 SH   SOLE   433,500 0 0
Versartis Inc COM 92529L102 1,013 500,000 SH   SOLE   500,000 0 0
SPDR S&P Biotech ETF S&P BIOTECH 78464A870 190,380 2,000,000 SH Put SOLE   2,000,000 0 0
Zosano Pharma Corp COM NEW 98979H202 2,856 700,000 SH   SOLE   700,000 0 0