The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100 27,403 449,300 SH   SOLE   449,300 0 0
ACCURAY INC COM 004397105 119 29,000 SH   SOLE   29,000 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 2,133 106,820 SH   SOLE   106,820 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 118 22,236 SH   SOLE   22,236 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 102,791 6,505,766 SH   SOLE   6,505,766 0 0
ALDER BIOPHARMACEUTICALS INC NOTE 2.500% 2/0 014339AA3 26,083 25,000,000 PRN   SOLE   25,000,000 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 60,747 489,300 SH   SOLE   489,300 0 0
AMEDISYS INC COM 023436108 233 2,725 SH   SOLE   2,725 0 0
AMICUS THERAPEUTICS INC COM 03152W109 164,193 10,511,732 SH   SOLE   10,511,732 0 0
ANAPTYSBIO INC COM 032724106 36,888 519,250 SH   SOLE   519,250 0 0
ANTHEM INC COM 036752103 34,752 146,000 SH   SOLE   146,000 0 0
ARGENX SE SPONSORED ADR 04016X101 55,790 673,300 SH   SOLE   673,300 0 0
ARRAY BIOPHARMA INC COM 04269X105 268,121 15,978,580 SH   SOLE   15,978,580 0 0
ARRAY BIOPHARMA INC NOTE 2.625%12/0 04269XAB1 25,524 19,000,000 PRN   SOLE   19,000,000 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 151,653 4,126,617 SH   SOLE   4,126,617 0 0
ATYR PHARMA INC COM 002120103 1,715 1,884,992 SH   SOLE   1,884,992 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 85,157 2,228,656 SH   SOLE   2,228,656 0 0
BEIGENE LTD SPONSORED ADR 07725L102 6,195 40,300 SH   SOLE   40,300 0 0
BLUEBIRD BIO INC COM 09609G100 42,141 268,500 SH   SOLE   268,500 0 0
CASTLIGHT HEALTH INC CL B 14862Q100 43 10,229 SH   SOLE   10,229 0 0
CATALENT INC COM 148806102 27,725 661,850 SH   SOLE   661,850 0 0
CENTENE CORP DEL COM 15135B101 62,589 507,985 SH   SOLE   507,985 0 0
CHIMERIX INC COM 16934W106 17,086 3,589,490 SH   SOLE   3,589,490 0 0
CLOVIS ONCOLOGY INC COM 189464100 79,964 1,758,600 SH   SOLE   1,758,600 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 39,693 2,957,765 SH   SOLE   2,957,765 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 5,998 262,400 SH   SOLE   262,400 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 58,123 1,477,080 SH   SOLE   1,477,080 0 0
EHEALTH INC COM 28238P109 30,451 1,377,895 SH   SOLE   1,377,895 0 0
EIDOS THERAPEUTICS INC COM 28249H104 3,885 191,000 SH   SOLE   191,000 0 0
ENDOLOGIX INC COM 29266S106 24,487 4,326,389 SH   SOLE   4,326,389 0 0
EPIZYME INC COM 29428V104 27,390 2,021,389 SH   SOLE   2,021,389 0 0
FATE THERAPEUTICS INC COM 31189P102 75,479 6,655,962 SH   SOLE   6,655,962 0 0
FLEXION THERAPEUTICS INC COM 33938J106 343 13,260 SH   SOLE   13,260 0 0
GLYCOMIMETICS INC COM 38000Q102 32,733 2,029,347 SH   SOLE   2,029,347 0 0
HESKA CORP COM RESTRC NEW 42805E306 36,822 354,776 SH   SOLE   354,776 0 0
HORIZON PHARMA PLC SHS G4617B105 427 25,800 SH   SOLE   25,800 0 0
ICU MED INC COM 44930G107 54,082 184,172 SH   SOLE   184,172 0 0
IMMUNOGEN INC COM 45253H101 119,834 12,315,942 SH   SOLE   12,315,942 0 0
INFLARX NV COM N44821101 65,393 2,027,700 SH   SOLE   2,027,700 0 0
INSMED INC COM PAR $.01 457669307 48,092 2,033,492 SH   SOLE   2,033,492 0 0
INSPIRE MED SYS INC COM 457730109 7,132 200,000 SH   SOLE   200,000 0 0
INVITAE CORP COM 46185L103 5,970 812,240 SH   SOLE   812,240 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 32,558 401,303 SH   SOLE   401,303 0 0
ISHARES TR US HLTHCR PR ETF 464288828 367 2,087 SH   SOLE   2,087 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 274 1,590 SH   SOLE   1,590 0 0
JOUNCE THERAPEUTICS INC COM 481116101 9,304 1,214,593 SH   SOLE   1,214,593 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 51,776 288,400 SH   SOLE   288,400 0 0
LIVANOVA PLC SHS G5509L101 59,871 599,788 SH   SOLE   599,788 0 0
MORPHOSYS AG SPONSORED ADS 617760202 38,526 1,269,800 SH   SOLE   1,269,800 0 0
MYOKARDIA INC COM 62857M105 356 7,170 SH   SOLE   7,170 0 0
NEURONETICS INC COM 64131A105 7,983 300,000 SH   SOLE   300,000 0 0
NEVRO CORP COM 64157F103 271 3,400 SH   SOLE   3,400 0 0
NEWLINK GENETICS CORP COM 651511107 7,672 1,611,746 SH   SOLE   1,611,746 0 0
NIGHTSTAR THERAPEUTICS PLC ADR 65413A101 28,567 1,785,446 SH   SOLE   1,785,446 0 0
ODONATE THERAPEUTICS INC COM 676079106 13,482 610,600 SH   SOLE   610,600 0 0
OVID THERAPEUTICS INC COM 690469101 951 121,950 SH   SOLE   121,950 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 28,812 2,235,207 SH   SOLE   2,235,207 0 0
PENUMBRA INC COM 70975L107 9,970 72,170 SH   SOLE   72,170 0 0
REGENXBIO INC COM 75901B107 112,014 1,561,175 SH   SOLE   1,561,175 0 0
SAGE THERAPEUTICS INC COM 78667J108 340 2,170 SH   SOLE   2,170 0 0
SAREPTA THERAPEUTICS INC COM 803607100 4,111 31,100 SH   SOLE   31,100 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 27,306 1,750,408 SH   SOLE   1,750,408 0 0
SENSEONICS HLDGS INC COM 81727U105 5,417 1,317,924 SH   SOLE   1,317,924 0 0
SURGERY PARTNERS INC COM 86881A100 9,257 621,300 SH   SOLE   621,300 0 0
SYNEOS HEALTH INC CL A 87166B102 46,040 981,673 SH   SOLE   981,673 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 16,655 1,631,237 SH   SOLE   1,631,237 0 0
TELADOC INC COM 87918A105 13,410 231,000 SH   SOLE   231,000 0 0
TELEFLEX INC COM 879369106 21,426 79,886 SH   SOLE   79,886 0 0
TRICIDA INC COM 89610F101 14,950 500,000 SH   SOLE   500,000 0 0
UNIQURE NV SHS N90064101 61,402 1,624,400 SH   SOLE   1,624,400 0 0
UNITEDHEALTH GROUP INC COM 91324P102 35,089 143,020 SH   SOLE   143,020 0 0
UNITY BIOTECHNOLOGY INC COM 91381U101 3,771 250,400 SH   SOLE   250,400 0 0
VALEANT PHARMACEUTICALS INTL COM 91911K102 208 8,930 SH   SOLE   8,930 0 0
VERICEL CORP COM 92346J108 1,754 180,873 SH   SOLE   180,873 0 0
VIEWRAY INC COM 92672L107 168 24,330 SH   SOLE   24,330 0 0
VITAL THERAPIES INC COM 92847R104 7,502 1,095,111 SH   SOLE   1,095,111 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 85,852 2,244,507 SH   SOLE   2,244,507 0 0
WELLCARE HEALTH PLANS INC COM 94946T106 87,417 355,009 SH   SOLE   355,009 0 0
XENCOR INC COM 98401F105 116,472 3,147,043 SH   SOLE   3,147,043 0 0
XERIS PHARMACEUTICALS INC COM 98422L107 45,792 2,412,642 SH   SOLE   2,412,642 0 0
ZOETIS INC CL A 98978V103 21,221 249,100 SH   SOLE   249,100 0 0