The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 364,181 890,309 SH   SOLE   890,309 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 25,207 1,650,780 SH   SOLE   1,650,780 0 0
AIMMUNE THERAPEUTICS INC COM 00900T107 37,155 1,381,759 SH   SOLE   1,381,759 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 29,279 1,853,101 SH   SOLE   1,853,101 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 147,295 1,186,427 SH   SOLE   1,186,427 0 0
ALIGN TECHNOLOGY INC COM 016255101 63,161 184,607 SH   SOLE   184,607 0 0
ALIMERA SCIENCES INC COM 016259103 2,948 3,013,793 SH   SOLE   3,013,793 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 65,146 3,340,806 SH   SOLE   3,340,806 0 0
AMICUS THERAPEUTICS INC COM 03152W109 96,350 6,168,347 SH   SOLE   6,168,347 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 240,156 2,549,431 SH   SOLE   2,549,431 0 0
CELGENE CORP COM 151020104 31,358 394,840 SH   SOLE   394,840 0 0
CLOVIS ONCOLOGY INC COM 189464100 226,168 4,974,007 SH   SOLE   4,974,007 0 0
CYTOKINETICS INC COM NEW 23282W605 1,027 123,686 SH   SOLE   123,686 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 6,136 500,913 SH   SOLE   500,913 0 0
EPIZYME INC COM 29428V104 93,578 6,906,158 SH   SOLE   6,906,158 0 0
EXACT SCIENCES CORP COM 30063P105 18,733 313,320 SH   SOLE   313,320 0 0
GILEAD SCIENCES INC COM 375558103 12,461 175,900 SH   SOLE   175,900 0 0
HISTOGENICS CORP COM 43358V109 757 302,922 SH   SOLE   302,922 0 0
IDERA PHARMACEUTICALS INC COM NEW 45168K306 814 616,355 SH   SOLE   616,355 0 0
IMMUNOMEDICS INC COM 452907108 113,696 4,803,364 SH   SOLE   4,803,364 0 0
INSMED INC COM PAR $.01 457669307 171,145 7,236,583 SH   SOLE   7,236,583 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 79,230 4,663,324 SH   SOLE   4,663,324 0 0
MELINTA THERAPEUTICS INC COM 58549G100 322 50,689 SH   SOLE   50,689 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 37,496 1,833,532 SH   SOLE   1,833,532 0 0
PROTHENA CORP PLC SHS G72800108 16,086 1,103,325 SH   SOLE   1,103,325 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 11,224 3,966,087 SH   SOLE   3,966,087 0 0
SAGE THERAPEUTICS INC COM 78667J108 130,317 832,536 SH   SOLE   832,536 0 0
SHIRE PLC SPONSORED ADR 82481R106 32,275 191,200 SH   SOLE   191,200 0 0
SOPHIRIS BIO INC COM NEW 83578Q209 694 247,000 SH   SOLE   247,000 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 109,169 3,521,565 SH   SOLE   3,521,565 0 0
SUNESIS PHARMACEUTICALS INC COM PAR 867328700 2,464 1,162,473 SH   SOLE   1,162,473 0 0
TREVENA INC COM 89532E109 491 341,300 SH   SOLE   341,300 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 183,895 1,625,234 SH   SOLE   1,625,234 0 0
VANDA PHARMACEUTICALS INC COM 921659108 79,166 4,155,670 SH   SOLE   4,155,670 0 0
WRIGHT MED GROUP N V ORD SHS 0.03 PAR N96617118 71,587 2,757,587 SH   SOLE   2,757,587 0 0
ZOGENIX INC COM NEW 98978L204 1,304 29,500 SH   SOLE   29,500 0 0