The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ASSEMBLY BIOSCIENCES INC COM 045396908 5,807 148,100 SH Call SOLE   148,100 0 0
ASCENDIS PHARMA A S COM 04351P901 17,096 257,000 SH Call SOLE   257,000 0 0
ASCENDIS PHARMA A S COM 04351P901 12,639 190,000 SH Call SOLE   190,000 0 0
CELGENE CORP COM 151020904 15,884 200,000 SH Call SOLE   200,000 0 0
CELGENE CORP COM 151020904 30,577 385,000 SH Call SOLE   385,000 0 0
FIBROGEN INC COM 31572Q908 21,910 350,000 SH Call SOLE   350,000 0 0
GILEAD SCIENCES INC COM 375558903 20,728 292,600 SH Call SOLE   292,600 0 0
IRONWOOD PHARMACEUTICALS INC COM 46333X908 11,044 577,600 SH Call SOLE   577,600 0 0
ACHILLION PHARMACEUTICALS INC COM 00448Q201 11,001 3,887,407 SH   SOLE   3,887,407 0 0
AQUINOX PHARMACEUTICALS INC COM 03842B101 3,048 1,150,000 SH   SOLE   1,150,000 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 115,401 2,943,164 SH   SOLE   2,943,164 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 36,274 2,961,147 SH   SOLE   2,961,147 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 12,682 1,039,500 SH   SOLE   1,039,500 0 0
FIBROGEN INC COM 31572Q808 126,280 2,017,250 SH   SOLE   2,017,250 0 0
IMMUNE DESIGN CORP COM 45252L103 20,191 4,437,600 SH   SOLE   4,437,600 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 787 412,000 SH   SOLE   412,000 0 0
IRONWOOD PHARMACEUTICALS INC COM 46333X108 119,501 6,250,073 SH   SOLE   6,250,073 0 0
KADMON HLDGS INC COM 48283N106 9,975 2,500,000 SH   SOLE   2,500,000 0 0
KURA ONCOLOGY INC COM 50127T109 71,065 3,904,675 SH   SOLE   3,904,675 0 0
MACROGENICS INC COM 556099109 29,955 1,450,606 SH   SOLE   1,450,606 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 55,798 199,500 SH   SOLE   199,500 0 0
ONCONOVA THERAPEUTICS INC COM 68232V306 3,034 7,500,000 SH   SOLE   7,500,000 0 0
SANGAMO THERAPEUTICS INC COM 800677106 21,437 1,509,671 SH   SOLE   1,509,671 0 0
WAVE LIFE SCIENCES LTD COM Y95308105 15,792 412,871 SH   SOLE   412,871 0 0
APTINYX INC COM 03836N103 992 41,037 SH   SOLE   41,037 0 0
ARCUS BIOSCIENCES INC COM 03969F109 27,373 2,236,387 SH   SOLE   2,236,387 0 0
CORVUS PHARMACEUTICALS INC COM 221015100 4,945 450,400 SH   SOLE   450,400 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 22,009 1,272,198 SH   SOLE   1,272,198 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 20,764 1,538,088 SH   SOLE   1,538,088 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 41,670 2,671,161 SH   SOLE   2,671,161 0 0
SURFACE ONCOLOGY INC COM 86877M209 14,529 890,808 SH   SOLE   890,808 0 0
UNITY BIOTECHNOLOGY INC COM 91381U101 25,310 1,680,644 SH   SOLE   1,680,644 0 0
ERYTECH PHARMA SPONSORED ADR 29604W108 1,734 153,964 SH   SOLE   153,964 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 97,390 1,464,067 SH   SOLE   1,464,067 0 0
DBV TECHNOLOGIES S A SPONSORED ADR 23306J101 5,750 298,100 SH   SOLE   298,100 0 0