The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U INC COM USD0.001 | COM | 90214J101 | 178,889 | 2,140,839 | SH | DFND | 368,137 | 0 | 1,772,702 | ||
| ABIOMED INC | COM | 003654100 | 80,562 | 196,950 | SH | DFND | 49,972 | 0 | 146,978 | ||
| ABRAXAS PETE CORP | COM | 003830106 | 973 | 336,693 | SH | DFND | 5,587 | 0 | 331,106 | ||
| ACACIA COMMUNICATIONS INC COM | COM | 00401C108 | 16,915 | 485,915 | SH | DFND | 136,012 | 0 | 349,903 | ||
| ACTIVISION BLIZZARD INC COM | COM | 00507V109 | 53,982 | 707,310 | SH | DFND | 189,507 | 0 | 517,803 | ||
| ADESTO TECHNOLOGIES CORP COM | COM | 00687D101 | 13,625 | 1,622,083 | SH | DFND | 31,507 | 0 | 1,590,576 | ||
| ADOBE SYS INC | COM | 00724F101 | 91,351 | 374,683 | SH | DFND | 85,998 | 0 | 288,685 | ||
| ADVANCED MICRO DEVICES INC COM | COM | 007903107 | 521 | 34,738 | SH | DFND | 10,952 | 0 | 23,786 | ||
| ADYEN NV 144A | COM | N3501V104 | 47,002 | 85,336 | SH | DFND | 7,936 | 0 | 77,400 | ||
| ALASKA COMM SYS GRP INC | COM | 01167P101 | 4,205 | 2,375,968 | SH | DFND | 385,340 | 0 | 1,990,628 | ||
| ALIBABA GROUP HLDG LTD SPONSORED ADS | COM | 01609W102 | 77,853 | 419,626 | SH | DFND | 106,826 | 0 | 312,800 | ||
| ALIGN TECHNOLOGY INC COM | COM | 016255101 | 148,907 | 435,223 | SH | DFND | 39,418 | 0 | 395,805 | ||
| ALLEGIANT TRAVEL CO COM | COM | 01748X102 | 14,196 | 102,166 | SH | DFND | 1,838 | 0 | 100,328 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 107,819 | 1,094,716 | SH | DFND | 191,788 | 0 | 902,928 | ||
| ALPHABET INC CAP STK CL A | COM | 02079K305 | 52,632 | 46,610 | SH | DFND | 3,158 | 0 | 43,452 | ||
| ALPHABET INC CAP STK CL C | COM | 02079K107 | 76,324 | 68,412 | SH | DFND | 8,285 | 0 | 60,127 | ||
| AMAZON.COM INC | COM | 023135106 | 504,223 | 296,637 | SH | DFND | 57,020 | 0 | 239,617 | ||
| AMBER ROAD INC COM USD0.001 | COM | 02318Y108 | 718 | 76,302 | SH | DFND | 10,369 | 0 | 65,933 | ||
| AMERICAN TOWER CORPORATION | COM | 03027X100 | 12,224 | 84,791 | SH | DFND | 8,109 | 0 | 76,682 | ||
| APACHE CORP | COM | 037411105 | 10,345 | 221,277 | SH | DFND | 15,527 | 0 | 205,750 | ||
| APPIAN CORP CL A | COM | 03782L101 | 6,666 | 184,357 | SH | DFND | 25,431 | 0 | 158,926 | ||
| APPLE INC | COM | 037833100 | 4,954 | 26,762 | SH | DFND | 6,607 | 0 | 20,155 | ||
| APPLIED OPTOELECTRONICS INC COM | COM | 03823U102 | 740 | 16,475 | SH | DFND | 1,197 | 0 | 15,278 | ||
| AQUANTIA CORP COM | COM | 03842Q108 | 19,692 | 1,700,497 | SH | DFND | 433,228 | 0 | 1,267,269 | ||
| ARISTA NETWORKS INC COM USD0.0001 | COM | 040413106 | 128,013 | 497,159 | SH | DFND | 26,172 | 0 | 470,987 | ||
| ASV HLDGS INC COM | COM | 00215L104 | 6,829 | 1,179,514 | SH | DFND | 77,315 | 0 | 1,102,199 | ||
| AT HOME GROUP INC COM | COM | 04650Y100 | 20,488 | 523,311 | SH | DFND | 60,046 | 0 | 463,265 | ||
| ATHENAHEALTH INC DELAWARE | COM | 04685W103 | 439 | 2,760 | SH | DFND | 281 | 0 | 2,479 | ||
| ATHENEX INC COM | COM | 04685N103 | 2,236 | 119,854 | SH | DFND | 8,862 | 0 | 110,992 | ||
| ATLASSIAN CORPORATION PLC COM USD0.1 CL A | COM | G06242104 | 19,366 | 309,751 | SH | DFND | 35,446 | 0 | 274,305 | ||
| AUTO TRADER GROUP PLC ORD GBP0.01 ISIN #GB00BVYVFW23 SEDOL #BVYV | COM | G06708104 | 5,315 | 945,184 | SH | DFND | 179,580 | 0 | 765,604 | ||
| AUTODESK INC COM | COM | 052769106 | 107,109 | 817,063 | SH | DFND | 109,675 | 0 | 707,388 | ||
| AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL # | COM | 05462W109 | 563 | 15,085 | SH | DFND | 15,000 | 0 | 85 | ||
| AXOGEN INC COM | COM | 05463X106 | 29,952 | 596,065 | SH | DFND | 96,569 | 0 | 499,496 | ||
| AZUL SA SPON ADR EACH REP 3 PFD SHS | COM | 05501U106 | 97,457 | 5,957,009 | SH | DFND | 874,278 | 0 | 5,082,731 | ||
| AZURRX BIOPHARMA INC COM | COM | 05502L105 | 1,782 | 555,196 | SH | DFND | 81,085 | 0 | 474,111 | ||
| BANDWIDTH INC COM CL A | COM | 05988J103 | 18,223 | 479,811 | SH | DFND | 83,731 | 0 | 396,080 | ||
| BIOSCRIP INC | COM | 09069N108 | 45,212 | 15,430,807 | SH | DFND | 3,482,589 | 0 | 11,948,218 | ||
| BLACK KNIGHT INC COM | COM | 09215C105 | 7,588 | 141,705 | SH | DFND | 1,880 | 0 | 139,825 | ||
| BLUEBIRD BIO INC COM | COM | 09609G100 | 21,717 | 138,366 | SH | DFND | 61,335 | 0 | 77,031 | ||
| BOSTON SCIENTIFIC CORP | COM | 101137107 | 1,413 | 43,205 | SH | DFND | 19,919 | 0 | 23,286 | ||
| BOX INC CL A | COM | 10316T104 | 8,193 | 327,867 | SH | DFND | 57,687 | 0 | 270,180 | ||
| BRIGHTCOVE INC COM USD0.001 | COM | 10921T101 | 288 | 29,872 | SH | DFND | 3,656 | 0 | 26,216 | ||
| C S X CORP | COM | 126408103 | 217 | 3,402 | SH | DFND | 75 | 0 | 3,327 | ||
| CALAMP CORP | COM | 128126109 | 4,228 | 180,472 | SH | DFND | 24,760 | 0 | 155,712 | ||
| CANNAE HLDGS INC COM | COM | 13765N107 | 4,470 | 240,985 | SH | DFND | 43,508 | 0 | 197,477 | ||
| CARBON BLACK INC COM | COM | 14081R103 | 914 | 35,136 | SH | DFND | 699 | 0 | 34,437 | ||
| CARL ZEISS MEDITEC AG NPV ISIN #DE0005313704 SEDOL #5922961 | COM | D14895102 | 1,197 | 17,705 | SH | DFND | 6,430 | 0 | 11,275 | ||
| CARROLS RESTAURANT GROUP INC COM | COM | 14574X104 | 7,614 | 512,727 | SH | DFND | 49,159 | 0 | 463,568 | ||
| CARVANA CO CL A | COM | 146869102 | 26,843 | 645,271 | SH | DFND | 79,122 | 0 | 566,149 | ||
| CASA SYS INC COM | COM | 14713L102 | 10,357 | 634,207 | SH | DFND | 53,238 | 0 | 580,969 | ||
| CATAPULT GROUP INTERNATIONAL ISIN #AU000000CAT9 SEDOL #BTL0Y76 | COM | Q2159P101 | 203 | 224,024 | SH | DFND | 17,428 | 0 | 206,596 | ||
| CAVCO INDS INC DEL | COM | 149568107 | 88 | 422 | SH | DFND | 66 | 0 | 356 | ||
| CD PROJEKT SA PLN1.00 ISIN #PLOPTTC00011 SEDOL #7302215 | COM | X0957E106 | 1,525 | 35,285 | SH | DFND | 18,265 | 0 | 17,020 | ||
| CHEGG INC COM USD0.001 | COM | 163092109 | 162,327 | 5,841,208 | SH | DFND | 1,064,566 | 0 | 4,776,642 | ||
| CHURCHILL DOWNS INC COM | COM | 171484108 | 1,438 | 4,850 | SH | DFND | 469 | 0 | 4,381 | ||
| CITIGROUP INC COM NEW | COM | 172967424 | 7,778 | 116,233 | SH | DFND | 24,806 | 0 | 91,427 | ||
| CLOUDERA INC COM | COM | 18914U100 | 1,495 | 109,579 | SH | DFND | 22,993 | 0 | 86,586 | ||
| CODEXIS INC COM USD0.0001 | COM | 192005106 | 3,160 | 219,435 | SH | DFND | 32,051 | 0 | 187,384 | ||
| COGNEX CORP COM | COM | 192422103 | 43 | 962 | SH | DFND | 0 | 0 | 962 | ||
| CONSTELLATION BRANDS INC CL A | COM | 21036P108 | 10,516 | 48,045 | SH | DFND | 4,151 | 0 | 43,894 | ||
| CONSTRUCTION PARTNERS INC COM CL A | COM | 21044C107 | 7,804 | 592,580 | SH | DFND | 38,010 | 0 | 554,570 | ||
| CORIUM INTL INC COM | COM | 21887L107 | 5,239 | 654,055 | SH | DFND | 96,653 | 0 | 557,402 | ||
| COSTAMARE INC COM USD0.0001 | COM | Y1771G102 | 565 | 70,799 | SH | DFND | 0 | 0 | 70,799 | ||
| COUPA SOFTWARE INC COM | COM | 22266L106 | 13,731 | 220,608 | SH | DFND | 43,178 | 0 | 177,430 | ||
| COVANTA HLDG CORP COM | COM | 22282E102 | 8,492 | 514,653 | SH | DFND | 92,056 | 0 | 422,597 | ||
| CRIMSON WINE GROUP COM USD0.01 | COM | 22662X100 | 527 | 57,002 | SH | DFND | 1,260 | 0 | 55,742 | ||
| DEERE & COMPANY | COM | 244199105 | 14 | 100 | SH | DFND | 0 | 0 | 100 | ||
| DELIVERY HERO AG NPV 144A ISIN #DE000A2E4K43 SEDOL #BZCNB42 | COM | D1T0KZ103 | 529 | 9,918 | SH | DFND | 8,013 | 0 | 1,905 | ||
| DELTA AIR LINES INC DEL COM NEW | COM | 247361702 | 6,287 | 126,911 | SH | DFND | 2,520 | 0 | 124,391 | ||
| DENALI THERAPEUTICS INC COM | COM | 24823R105 | 208 | 13,616 | SH | DFND | 27 | 0 | 13,589 | ||
| DEXCOM INC | COM | 252131107 | 56,677 | 596,730 | SH | DFND | 46,064 | 0 | 550,666 | ||
| DIGI INTL INC COM | COM | 253798102 | 13,411 | 1,015,964 | SH | DFND | 175,066 | 0 | 840,898 | ||
| DOCUSIGN INC COM | COM | 256163106 | 8,816 | 166,502 | SH | DFND | 26,669 | 0 | 139,833 | ||
| DOMO INC COM CL B | COM | 257554105 | 8,969 | 328,517 | SH | DFND | 6,236 | 0 | 322,281 | ||
| ECO STIM ENERGY SOLUTIONS INC COM | COM | 27888D101 | 268 | 412,167 | SH | DFND | 29,667 | 0 | 382,500 | ||
| ECOSYNTHETIX INC COM ISIN #CA27923D1087 SEDOL #B4XBZ35 | COM | 27923D108 | 80 | 62,942 | SH | DFND | 7,325 | 0 | 55,617 | ||
| EHEALTH INC COM | COM | 28238P109 | 2,084 | 94,307 | SH | DFND | 14,068 | 0 | 80,239 | ||
| ELBIT SYSTEMS LTD | COM | M3760D101 | 31,986 | 269,380 | SH | DFND | 75,451 | 0 | 193,929 | ||
| ELECTRONIC ARTS | COM | 285512109 | 2,851 | 20,217 | SH | DFND | 2,453 | 0 | 17,764 | ||
| ENPHASE ENERGY INC COM USD0.00001 | COM | 29355A107 | 21,223 | 3,153,516 | SH | DFND | 359,869 | 0 | 2,793,647 | ||
| ENTERCOM COMMUNICATIONS CORP CL A | COM | 293639100 | 15,043 | 1,992,390 | SH | DFND | 279,630 | 0 | 1,712,760 | ||
| ENZO BIOCHEM INC | COM | 294100102 | 3,961 | 763,219 | SH | DFND | 165,378 | 0 | 597,841 | ||
| EPAM SYS INC COM USD0.001 | COM | 29414B104 | 74,228 | 597,026 | SH | DFND | 35,036 | 0 | 561,990 | ||
| EROS INTERNATIONAL COM GBP0.30 | COM | G3788M114 | 46,182 | 3,552,426 | SH | DFND | 889,472 | 0 | 2,662,954 | ||
| ESPERION THERAPEUTICS INC COM USD0.001 | COM | 29664W105 | 66 | 1,674 | SH | DFND | 204 | 0 | 1,470 | ||
| ETSY INC COM | COM | 29786A106 | 190,132 | 4,506,559 | SH | DFND | 892,149 | 0 | 3,614,410 | ||
| EVERBRIDGE INC COM | COM | 29978A104 | 23,491 | 495,382 | SH | DFND | 86,103 | 0 | 409,279 | ||
| EXACT SCIENCES CORP | COM | 30063P105 | 117,786 | 1,969,989 | SH | DFND | 334,503 | 0 | 1,635,486 | ||
| EXTRACTION OIL AND GAS INC COM | COM | 30227M105 | 18,190 | 1,238,224 | SH | DFND | 202,090 | 0 | 1,036,134 | ||
| EXXON MOBIL CORP | COM | 30231G102 | 116 | 1,400 | SH | DFND | 1,400 | 0 | 0 | ||
| FACEBOOK INC COM USD0.000006 CL A | COM | 30303M102 | 238,765 | 1,228,719 | SH | DFND | 208,321 | 0 | 1,020,398 | ||
| FIVE BELOW INC COM | COM | 33829M101 | 103,667 | 1,060,970 | SH | DFND | 71,800 | 0 | 989,170 | ||
| FLEXION THERAPEUTICS INC COM | COM | 33938J106 | 89,197 | 3,450,547 | SH | DFND | 550,146 | 0 | 2,900,401 | ||
| FLOOR &DECOR HLDGS INC CL A | COM | 339750101 | 123,643 | 2,506,445 | SH | DFND | 381,253 | 0 | 2,125,192 | ||
| FORESCOUT TECHNOLOGIES INC COM | COM | 34553D101 | 30,495 | 890,093 | SH | DFND | 137,704 | 0 | 752,389 | ||
| FOUNDATION MEDICINE INC USD0.0001 | COM | 350465100 | 182,713 | 1,336,595 | SH | DFND | 350,470 | 0 | 986,125 | ||
| FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31 | COM | 351858105 | 6,255 | 85,658 | SH | DFND | 2,715 | 0 | 82,943 | ||
| FRESHPET INC COM | COM | 358039105 | 73,325 | 2,671,203 | SH | DFND | 236,954 | 0 | 2,434,249 | ||
| FRONTIER DEVELOPMENTS PLC GBP0.005 ISIN #GB00BBT32N39 SEDOL #BBT | COM | G36793100 | 599 | 33,881 | SH | DFND | 18,595 | 0 | 15,286 | ||
| FUSION CONNECT INC COM | COM | 36116X102 | 2,362 | 599,416 | SH | DFND | 176,599 | 0 | 422,817 | ||
| GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5 | COM | B44170106 | 19,210 | 208,422 | SH | DFND | 99,871 | 0 | 108,551 | ||
| GASLOG LTD COM USD0.01 | COM | G37585109 | 4,203 | 220,044 | SH | DFND | 41,252 | 0 | 178,792 | ||
| GENERAL MTRS CO COM | COM | 37045V100 | 169 | 4,288 | SH | DFND | 1,233 | 0 | 3,055 | ||
| GEOPARK LIMITED COM USD0.001 | COM | G38327105 | 3,535 | 171,283 | SH | DFND | 458 | 0 | 170,825 | ||
| GLAUKOS CORP COM | COM | 377322102 | 52,625 | 1,294,902 | SH | DFND | 257,819 | 0 | 1,037,083 | ||
| GLOBANT SA USD1.20 | COM | L44385109 | 45,082 | 793,840 | SH | DFND | 212,195 | 0 | 581,645 | ||
| GLOBUS MED INC CL A NEW | COM | 379577208 | 10,386 | 205,818 | SH | DFND | 37,030 | 0 | 168,788 | ||
| GOLAR LNG LIMITED COM STK USD1.00 | COM | G9456A100 | 19,863 | 674,220 | SH | DFND | 119,482 | 0 | 554,738 | ||
| GOLD STD VENTURES CORP COM ISIN #CA3807381049 SEDOL #B05J9S2 | COM | 380738104 | 1,221 | 894,270 | SH | DFND | 9,110 | 0 | 885,160 | ||
| GOOSEHEAD INS INC COM CL A | COM | 38267D109 | 55,822 | 2,236,470 | SH | DFND | 41,618 | 0 | 2,194,852 | ||
| GRACE W R & CO DEL NEW | COM | 38388F108 | 19,622 | 267,657 | SH | DFND | 49,392 | 0 | 218,265 | ||
| GREENSKY INC CL A | COM | 39572G100 | 229 | 10,839 | SH | DFND | 0 | 0 | 10,839 | ||
| GRUBHUB INC COM USD0.0001 | COM | 400110102 | 4,518 | 43,069 | SH | DFND | 11,942 | 0 | 31,127 | ||
| GRUPO FINANCIERO GALICIA SA ADR EACH REPR 10 CLASS B ARS1 LVL11 | COM | 399909100 | 4,026 | 122,073 | SH | DFND | 3,813 | 0 | 118,260 | ||
| GRUPO SUPERVIELLE S.A. SPON ADS EACH REP 5 ORD SHS CL B | COM | 40054A108 | 565 | 53,433 | SH | DFND | 28,135 | 0 | 25,298 | ||
| GTT COMMUNICATIONS INC COM USD0.0001 | COM | 362393100 | 86,193 | 1,915,389 | SH | DFND | 324,255 | 0 | 1,591,134 | ||
| GUIDEWIRE SOFTWARE INC COM USD0.0001 | COM | 40171V100 | 253 | 2,849 | SH | DFND | 2,060 | 0 | 789 | ||
| H &E EQUIPMENT SERVICES INC COM | COM | 404030108 | 3,207 | 85,266 | SH | DFND | 381 | 0 | 84,885 | ||
| HDFC BANK LTD ADS EACH REPR 3 INR10(MGT) | COM | 40415F101 | 49,324 | 469,662 | SH | DFND | 124,461 | 0 | 345,201 | ||
| HEALTHEQUITY INC COM | COM | 42226A107 | 5,880 | 78,302 | SH | DFND | 5,220 | 0 | 73,082 | ||
| HERC HLDGS INC COM | COM | 42704L104 | 202 | 3,581 | SH | DFND | 2,550 | 0 | 1,031 | ||
| HOMOLOGY MEDICINES INC COM | COM | 438083107 | 20 | 1,000 | SH | DFND | 0 | 0 | 1,000 | ||
| HUBSPOT INC COM | COM | 443573100 | 115,736 | 922,934 | SH | DFND | 70,518 | 0 | 852,416 | ||
| ICICI BANK LIMITED ADR EACH REPR 2 ORD INR10(SPON) | COM | 45104G104 | 3,612 | 449,751 | SH | DFND | 28,802 | 0 | 420,949 | ||
| ILLUMINA INC COM | COM | 452327109 | 27,235 | 97,515 | SH | DFND | 8,564 | 0 | 88,951 | ||
| IMPINJ INC COM | COM | 453204109 | 20,121 | 910,053 | SH | DFND | 284,275 | 0 | 625,778 | ||
| INFINERA CORPORATION COM | COM | 45667G103 | 377 | 38,016 | SH | DFND | 2,352 | 0 | 35,664 | ||
| INPHI CORPORATION COM USD0.001 | COM | 45772F107 | 3,937 | 120,730 | SH | DFND | 31,007 | 0 | 89,723 | ||
| INSPIRE MED SYS INC COM | COM | 457730109 | 5,010 | 140,485 | SH | DFND | 6,332 | 0 | 134,153 | ||
| INSULET CORP COM | COM | 45784P101 | 1,844 | 21,513 | SH | DFND | 7,827 | 0 | 13,686 | ||
| INTERSECT ENT INC COM | COM | 46071F103 | 3,123 | 83,391 | SH | DFND | 19,802 | 0 | 63,589 | ||
| INTUITIVE SURGICAL INC COM NEW | COM | 46120E602 | 102,283 | 213,767 | SH | DFND | 16,371 | 0 | 197,396 | ||
| IRHYTHM TECHNOLOGIES INC COM | COM | 450056106 | 10,368 | 127,793 | SH | DFND | 16,815 | 0 | 110,978 | ||
| IROBOT CORP COM | COM | 462726100 | 6,927 | 91,423 | SH | DFND | 14,035 | 0 | 77,388 | ||
| JD COM INC SPONSORED ADR REPSTG COM CL A | COM | 47215P106 | 48,191 | 1,237,244 | SH | DFND | 358,113 | 0 | 879,131 | ||
| KANSAS CITY SOUTHERN COM | COM | 485170302 | 6,170 | 58,232 | SH | DFND | 3,263 | 0 | 54,969 | ||
| KB HOME COM | COM | 48666K109 | 6,606 | 242,511 | SH | DFND | 13,888 | 0 | 228,623 | ||
| KORNIT DIGITAL LTD ORD ILS0.01 | COM | M6372Q113 | 19,601 | 1,101,161 | SH | DFND | 64,214 | 0 | 1,036,947 | ||
| LENNAR CORP CL B | COM | 526057302 | 176 | 4,134 | SH | DFND | 94 | 0 | 4,040 | ||
| LGI HOMES INC COM | COM | 50187T106 | 97,914 | 1,696,073 | SH | DFND | 212,347 | 0 | 1,483,726 | ||
| LHC GROUP INC COM | COM | 50187A107 | 19,464 | 227,414 | SH | DFND | 39,112 | 0 | 188,302 | ||
| LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP | COM | 531229706 | 5,437 | 211,467 | SH | DFND | 2,013 | 0 | 209,454 | ||
| LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP | COM | 531229888 | 17,274 | 667,988 | SH | DFND | 98,492 | 0 | 569,496 | ||
| LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA | COM | 531229854 | 47,083 | 1,268,063 | SH | DFND | 90,746 | 0 | 1,177,317 | ||
| LILIS ENERGY INC COM NEW | COM | 532403201 | 3,840 | 738,507 | SH | DFND | 232,504 | 0 | 506,003 | ||
| LIVEPERSON INC | COM | 538146101 | 65,375 | 3,098,337 | SH | DFND | 214,223 | 0 | 2,884,114 | ||
| LONZA GROUP AG-REG ISIN #CH0013841017 SEDOL #7333378 | COM | H50524133 | 29,839 | 112,441 | SH | DFND | 45,696 | 0 | 66,745 | ||
| LOVESAC COMPANY COM | COM | 54738L109 | 7,761 | 374,046 | SH | DFND | 0 | 0 | 374,046 | ||
| LULULEMON ATHLETICA INC COM | COM | 550021109 | 228 | 1,829 | SH | DFND | 466 | 0 | 1,363 | ||
| LUMBER LIQUIDATORS HLDGS INC COM | COM | 55003T107 | 4,434 | 182,081 | SH | DFND | 32,058 | 0 | 150,023 | ||
| LUMENTUM HLDGS INC COM | COM | 55024U109 | 64,624 | 1,116,139 | SH | DFND | 233,339 | 0 | 882,800 | ||
| MADISON SQUARE GARDEN CO NEW CL A | COM | 55825T103 | 8,306 | 26,778 | SH | DFND | 5,265 | 0 | 21,513 | ||
| MAKEMYTRIP LTD USD0.0005 | COM | V5633W109 | 3,810 | 105,392 | SH | DFND | 25,162 | 0 | 80,230 | ||
| MARTIN MARIETTA MATLS INC | COM | 573284106 | 61,938 | 277,339 | SH | DFND | 15,835 | 0 | 261,504 | ||
| MASTERCARD INCORPORATED CL A | COM | 57636Q104 | 19,411 | 98,771 | SH | DFND | 20,386 | 0 | 78,385 | ||
| MATCH GROUP INC COM | COM | 57665R106 | 5,295 | 136,688 | SH | DFND | 19,909 | 0 | 116,779 | ||
| MEDMEN ENTERPRISES INC COM NPV ISIN #CA58507M1077 SEDOL #BYVPJP9 | COM | 58507M107 | 619 | 187,261 | SH | DFND | 38,662 | 0 | 148,599 | ||
| MERCADOLIBRE INC | COM | 58733R102 | 40,479 | 135,414 | SH | DFND | 31,945 | 0 | 103,469 | ||
| MERCURY SYS INC COM | COM | 589378108 | 154 | 4,049 | SH | DFND | 723 | 0 | 3,326 | ||
| METRO BANK PLC ORD GBP0.000001 ISIN #GB00BZ6STL67 SEDOL #BZ6STL6 | COM | G60640102 | 134,934 | 3,158,315 | SH | DFND | 525,421 | 0 | 2,632,894 | ||
| MICRON TECHNOLOGY | COM | 595112103 | 1,780 | 33,946 | SH | DFND | 12,873 | 0 | 21,073 | ||
| MICROSOFT CORP | COM | 594918104 | 56,883 | 576,849 | SH | DFND | 143,628 | 0 | 433,221 | ||
| MIMECAST LIMITED COM USD0.012 | COM | G14838109 | 1,403 | 34,048 | SH | DFND | 3,063 | 0 | 30,985 | ||
| MONGODB INC CL A | COM | 60937P106 | 72,666 | 1,464,148 | SH | DFND | 162,214 | 0 | 1,301,934 | ||
| MONOLITHIC PWR SYS INC COM | COM | 609839105 | 14,171 | 106,018 | SH | DFND | 6,090 | 0 | 99,928 | ||
| NEOPHOTONICS CORP COM | COM | 64051T100 | 55 | 8,890 | SH | DFND | 2,658 | 0 | 6,232 | ||
| NETFLIX COM INC COM | COM | 64110L106 | 698,975 | 1,785,695 | SH | DFND | 312,851 | 0 | 1,472,844 | ||
| NETSHOES CAYMAN LTD COM USD0.0033 | COM | G6455X107 | 1,659 | 699,951 | SH | DFND | 339,201 | 0 | 360,750 | ||
| NEW RELIC INC COM | COM | 64829B100 | 10,620 | 105,577 | SH | DFND | 19,992 | 0 | 85,585 | ||
| NEW YORK TIMES CO CL A | COM | 650111107 | 109,429 | 4,225,072 | SH | DFND | 1,056,100 | 0 | 3,168,972 | ||
| NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV | COM | 654445303 | 24,362 | 596,337 | SH | DFND | 29,711 | 0 | 566,626 | ||
| NINTENDO CO LTD NPV ISIN #JP3756600007 SEDOL #6639550 | COM | J51699106 | 475 | 1,452 | SH | DFND | 378 | 0 | 1,074 | ||
| NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST | COM | 65506L105 | 59 | 1,159 | SH | DFND | 0 | 0 | 1,159 | ||
| NRG ENERGY INC COM NEW | COM | 629377508 | 484 | 15,762 | SH | DFND | 342 | 0 | 15,420 | ||
| NUTANIX INC CL A | COM | 67059N108 | 1,695 | 32,865 | SH | DFND | 1,644 | 0 | 31,221 | ||
| NUVECTRA CORP COM | COM | 67075N108 | 23,987 | 1,168,412 | SH | DFND | 201,711 | 0 | 966,701 | ||
| NV5 GLOBAL INC COM | COM | 62945V109 | 11,656 | 168,199 | SH | DFND | 4,116 | 0 | 164,083 | ||
| NVIDIA CORP | COM | 67066G104 | 52,516 | 221,679 | SH | DFND | 70,863 | 0 | 150,816 | ||
| NXSTAGE MED INC COM | COM | 67072V103 | 369 | 13,237 | SH | DFND | 1,491 | 0 | 11,746 | ||
| OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74 | COM | G6718L106 | 200,524 | 14,781,795 | SH | DFND | 2,452,667 | 0 | 12,329,128 | ||
| OKTA INC CL A | COM | 679295105 | 81,948 | 1,626,913 | SH | DFND | 154,226 | 0 | 1,472,687 | ||
| OVERSTOCK COM INC DEL COM | COM | 690370101 | 13,855 | 411,729 | SH | DFND | 39,237 | 0 | 372,492 | ||
| PALO ALTO NETWORKS INC COM USD0.0001 | COM | 697435105 | 1,922 | 9,353 | SH | DFND | 1,975 | 0 | 7,378 | ||
| PARAMOUNT RESOURCES LIMITED COM NPV CLASS A ISIN #CA6993202069 S | COM | 699320206 | 8,547 | 755,107 | SH | DFND | 45,356 | 0 | 709,751 | ||
| PAYPAL HLDGS INC COM | COM | 70450Y103 | 21,736 | 261,034 | SH | DFND | 29,336 | 0 | 231,698 | ||
| PDF SOLUTIONS INC | COM | 693282105 | 14,243 | 1,188,886 | SH | DFND | 78,777 | 0 | 1,110,109 | ||
| PENSKE AUTOMOTIVE GROUP INC | COM | 70959W103 | 3,410 | 72,792 | SH | DFND | 15,902 | 0 | 56,890 | ||
| PENUMBRA INC COM | COM | 70975L107 | 1,064 | 7,701 | SH | DFND | 1,901 | 0 | 5,800 | ||
| PIVOTAL SOFTWARE INC COM CL A | COM | 72582H107 | 82,195 | 3,386,677 | SH | DFND | 296,559 | 0 | 3,090,118 | ||
| PLANET FITNESS INC CL A | COM | 72703H101 | 1,463 | 33,305 | SH | DFND | 6,574 | 0 | 26,731 | ||
| PLURALSIGHT INC COM CL A | COM | 72941B106 | 6,554 | 268,039 | SH | DFND | 48,894 | 0 | 219,145 | ||
| POLARITYTE INC COM | COM | 731094108 | 20,229 | 859,354 | SH | DFND | 55,822 | 0 | 803,532 | ||
| POOL CORP COM | COM | 73278L105 | 61,210 | 404,026 | SH | DFND | 60,160 | 0 | 343,866 | ||
| PROOFPOINT INC COM USD0.0001 | COM | 743424103 | 6,035 | 52,336 | SH | DFND | 3,827 | 0 | 48,509 | ||
| PTC INC COM | COM | 69370C100 | 186 | 1,988 | SH | DFND | 1,149 | 0 | 839 | ||
| Q2 HLDGS INC COM | COM | 74736L109 | 18,713 | 328,015 | SH | DFND | 47,654 | 0 | 280,361 | ||
| QUANTERIX CORP COM | COM | 74766Q101 | 15,665 | 1,090,893 | SH | DFND | 183,893 | 0 | 907,000 | ||
| QUOTIENT LTD COM NPV | COM | G73268107 | 1,702 | 211,990 | SH | DFND | 16,049 | 0 | 195,941 | ||
| R1 RCM INC COM | COM | 749397105 | 4,417 | 508,831 | SH | DFND | 80,995 | 0 | 427,836 | ||
| REPUBLIC FIRST BANCORP INC COM | COM | 760416107 | 1,900 | 242,003 | SH | DFND | 64,278 | 0 | 177,725 | ||
| RIGHTMOVE PLC WINTERHILL SHS ISIN #GB00B2987V85 SEDOL #B2987V8 | COM | G75657109 | 23,558 | 336,040 | SH | DFND | 32,180 | 0 | 303,860 | ||
| RINGCENTRAL INC-CLASS A | COM | 76680R206 | 185,712 | 2,639,824 | SH | DFND | 509,467 | 0 | 2,130,357 | ||
| ROKU INC COM CL A | COM | 77543R102 | 126,177 | 2,960,515 | SH | DFND | 667,443 | 0 | 2,293,072 | ||
| ROYAL GOLD INC COM ISIN #US7802871084 SEDOL #2430553 | COM | 780287108 | 18 | 198 | SH | DFND | 0 | 0 | 198 | ||
| SAFETY INS GROUP INC | COM | 78648T100 | 418 | 4,893 | SH | DFND | 1,075 | 0 | 3,818 | ||
| SAILPOINT TECHNLGIES HLDGS INC COM | COM | 78781P105 | 21,860 | 890,778 | SH | DFND | 90,286 | 0 | 800,492 | ||
| SALESFORCE COM INC | COM | 79466L302 | 87,391 | 640,694 | SH | DFND | 193,760 | 0 | 446,934 | ||
| SANGAMO THERAPEUTICS INC COM | COM | 800677106 | 396 | 27,882 | SH | DFND | 7,213 | 0 | 20,669 | ||
| SAREPTA THERAPEUTICS INC COM | COM | 803607100 | 130,313 | 985,874 | SH | DFND | 228,665 | 0 | 757,209 | ||
| SCIENTIFIC GAMES CORP COM | COM | 80874P109 | 4,004 | 81,463 | SH | DFND | 12,413 | 0 | 69,050 | ||
| SEASPINE HLDGS CORP COM | COM | 81255T108 | 4,120 | 326,437 | SH | DFND | 60,422 | 0 | 266,015 | ||
| SENESTECH INC COM | COM | 81720R109 | 2,181 | 1,338,017 | SH | DFND | 109,081 | 0 | 1,228,936 | ||
| SENSEONICS HLDGS INC COM | COM | 81727U105 | 74,936 | 18,232,633 | SH | DFND | 3,936,351 | 0 | 14,296,282 | ||
| SEQUANS COMMUNICATIONS SPON ADR EA REPR 1 ORD SHS | COM | 817323108 | 192 | 94,294 | SH | DFND | 11,651 | 0 | 82,643 | ||
| SERVICENOW INC COM USD0.001 | COM | 81762P102 | 25,662 | 148,791 | SH | DFND | 28,175 | 0 | 120,616 | ||
| SHAKE SHACK INC CL A | COM | 819047101 | 113,558 | 1,715,896 | SH | DFND | 152,333 | 0 | 1,563,563 | ||
| SHERWIN WILLIAMS CO | COM | 824348106 | 1,145 | 2,809 | SH | DFND | 59 | 0 | 2,750 | ||
| SHOPIFY INC COM NPV CL A ISIN #CA82509L1076 SEDOL #BX865C7 | COM | 82509L107 | 29,730 | 203,787 | SH | DFND | 87,845 | 0 | 115,942 | ||
| SHOTSPOTTER INC COM | COM | 82536T107 | 84,241 | 2,220,947 | SH | DFND | 511,788 | 0 | 1,709,159 | ||
| SIENTRA INC COM USD0.01 | COM | 82621J105 | 26,787 | 1,373,007 | SH | DFND | 278,042 | 0 | 1,094,965 | ||
| SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2 | COM | 828363101 | 8,296 | 3,983,035 | SH | DFND | 180,482 | 0 | 3,802,553 | ||
| SITEONE LANDSCAPE SUPPLY INC COM | COM | 82982L103 | 32,733 | 389,817 | SH | DFND | 47,130 | 0 | 342,687 | ||
| SIX FLAGS ENTMT CORP NEW COM | COM | 83001A102 | 7,782 | 111,099 | SH | DFND | 42,430 | 0 | 68,669 | ||
| SMARTSHEET INC COM CL A | COM | 83200N103 | 13,242 | 509,907 | SH | DFND | 2,342 | 0 | 507,565 | ||
| SNAP INC CL A | COM | 83304A106 | 255 | 19,491 | SH | DFND | 19,491 | 0 | 0 | ||
| SOCIAL CAP HEDOSOPHIA HLDGS CORP UNIT 1 CL A & 1/3 WT EXP ISIN # | COM | G8250R111 | 2,020 | 184,152 | SH | DFND | 33,557 | 0 | 150,595 | ||
| SOLARIS OILFIELD INFRSTR INC COM CL A | COM | 83418M103 | 19,485 | 1,363,562 | SH | DFND | 122,015 | 0 | 1,241,547 | ||
| SONY CORP SPON ADR EACH REPR 1 ORD | COM | 835699307 | 31 | 600 | SH | DFND | 0 | 0 | 600 | ||
| SPARK THERAPEUTICS INC COM | COM | 84652J103 | 43,535 | 526,044 | SH | DFND | 188,537 | 0 | 337,507 | ||
| SPIRIT AIRLS INC COM | COM | 848577102 | 8,463 | 232,818 | SH | DFND | 7,908 | 0 | 224,910 | ||
| SPLUNK INC COM USD0.001 | COM | 848637104 | 5,082 | 51,279 | SH | DFND | 5,245 | 0 | 46,034 | ||
| SQUARE INC CL A | COM | 852234103 | 94,466 | 1,532,546 | SH | DFND | 140,435 | 0 | 1,392,111 | ||
| SS&C TECHNOLOGIES HLDGS INC COM | COM | 78467J100 | 51,620 | 994,613 | SH | DFND | 149,755 | 0 | 844,858 | ||
| STAMPS COM INC COM NEW | COM | 852857200 | 72 | 284 | SH | DFND | 88 | 0 | 196 | ||
| STAR BULK CARRIERS CORP COM USD0.01(POST REV SPLIT) | COM | Y8162K204 | 10,187 | 792,113 | SH | DFND | 133,560 | 0 | 658,553 | ||
| STARS GROUP INC(THE) COM NPV ISIN #CA85570W1005 SEDOL #BDG1MJ0 | COM | 85570W100 | 5,739 | 158,106 | SH | DFND | 2,486 | 0 | 155,620 | ||
| STITCH FIX INC COM CL A | COM | 860897107 | 19,719 | 718,617 | SH | DFND | 0 | 0 | 718,617 | ||
| SUMMIT MATLS INC CL A | COM | 86614U100 | 9,071 | 345,564 | SH | DFND | 6,591 | 0 | 338,973 | ||
| SUNOPTA INC COM ISIN #CA8676EP1086 SEDOL #2817510 | COM | 8676EP108 | 7,393 | 880,173 | SH | DFND | 162,721 | 0 | 717,452 | ||
| SUNRUN INC COM | COM | 86771W105 | 575 | 43,744 | SH | DFND | 4,346 | 0 | 39,398 | ||
| SVB FINL GROUP | COM | 78486Q101 | 7,756 | 26,858 | SH | DFND | 5,457 | 0 | 21,401 | ||
| T MOBILE US INC COM | COM | 872590104 | 726 | 12,143 | SH | DFND | 1,550 | 0 | 10,593 | ||
| TACTILE SYS TECHNOLOGY INC COM | COM | 87357P100 | 13,766 | 264,737 | SH | DFND | 47,122 | 0 | 217,615 | ||
| TAKE-TWO INTERACTIVE SOFTWARE COM | COM | 874054109 | 43,151 | 364,575 | SH | DFND | 128,613 | 0 | 235,962 | ||
| TAL EDUCATION GROUP SPON ADS EACH REP 0.3333 CL A ORD SHS | COM | 874080104 | 88,097 | 2,393,944 | SH | DFND | 445,269 | 0 | 1,948,675 | ||
| TALEND SA ADR EACH REP 1 ORD SHS | COM | 874224207 | 2,393 | 38,424 | SH | DFND | 7,769 | 0 | 30,655 | ||
| TELADOC INC COM | COM | 87918A105 | 85,756 | 1,477,276 | SH | DFND | 460,534 | 0 | 1,016,742 | ||
| TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM | COM | G87572163 | 78,611 | 1,566,115 | SH | DFND | 412,855 | 0 | 1,153,260 | ||
| TESLA INC COM | COM | 88160R101 | 176,401 | 514,365 | SH | DFND | 117,961 | 0 | 396,404 | ||
| TRANSDIGM GROUP INC COM | COM | 893641100 | 5,942 | 17,216 | SH | DFND | 151 | 0 | 17,065 | ||
| TSO3 INC COM ISIN #CA8730151013 SEDOL #2798518 | COM | 873015101 | 3,096 | 4,378,796 | SH | DFND | 298,367 | 0 | 4,080,429 | ||
| TWITTER INC COM USD0.000005 | COM | 90184L102 | 66,236 | 1,516,745 | SH | DFND | 132,367 | 0 | 1,384,378 | ||
| UBIQUITI NETWORKS INC COM USD0.001 | COM | 90347A100 | 134 | 1,577 | SH | DFND | 206 | 0 | 1,371 | ||
| ULTIMATE SOFTWARE GROUP INC | COM | 90385D107 | 237 | 923 | SH | DFND | 555 | 0 | 368 | ||
| UNDER ARMOUR INC CL C | COM | 904311206 | 5,220 | 247,648 | SH | DFND | 52,058 | 0 | 195,590 | ||
| UNDER ARMOUR INC COM STK USD0.000333 CLASS A | COM | 904311107 | 218 | 9,685 | SH | DFND | 1,799 | 0 | 7,886 | ||
| UNITY BIOTECHNOLOGY INC COM | COM | 91381U101 | 301 | 20,000 | SH | DFND | 5,644 | 0 | 14,356 | ||
| USA TECHNOLOGIES INC COM NO PAR | COM | 90328S500 | 22,894 | 1,635,291 | SH | DFND | 389,696 | 0 | 1,245,595 | ||
| VALERITAS HLDGS INC COM NEW | COM | 91914N202 | 92 | 68,338 | SH | DFND | 7,961 | 0 | 60,377 | ||
| VANECK VECTORS ETF TR GOLD MINERS ETF | COM | 92189F106 | 15,605 | 699,463 | SH | DFND | 20,650 | 0 | 678,813 | ||
| VEEVA SYS INC CL A COM | COM | 922475108 | 11,634 | 151,370 | SH | DFND | 31,436 | 0 | 119,934 | ||
| VERRICA PHARMACEUTICALS INC COM | COM | 92511W108 | 2,941 | 149,044 | SH | DFND | 0 | 0 | 149,044 | ||
| VOCERA COMMUNICATIONS INC COM | COM | 92857F107 | 6,785 | 227,004 | SH | DFND | 38,917 | 0 | 188,087 | ||
| W R BERKLEY CORPORATION COM | COM | 084423102 | 4,433 | 61,225 | SH | DFND | 15,535 | 0 | 45,690 | ||
| WEIGHT WATCHERS INTL INC NEW | COM | 948626106 | 184,031 | 1,820,283 | SH | DFND | 247,382 | 0 | 1,572,901 | ||
| WHEATON PRECIOUS METALS CORP COM NPV ISIN #CA9628791027 SEDOL #B | COM | 962879102 | 1,936 | 87,739 | SH | DFND | 635 | 0 | 87,104 | ||
| WORKDAY INC COM USD0.001 CL A | COM | 98138H101 | 17,197 | 141,980 | SH | DFND | 30,321 | 0 | 111,659 | ||
| WORLD WRESTLING ENTERTAINMENT INC CL A | COM | 98156Q108 | 135,144 | 1,855,865 | SH | DFND | 306,357 | 0 | 1,549,508 | ||
| ZAI LAB LTD-ADR | COM | 98887Q104 | 20,038 | 861,871 | SH | DFND | 339,325 | 0 | 522,546 | ||
| ZEBRA TECHNOLOGIES CORP CL A | COM | 989207105 | 180 | 1,260 | SH | DFND | 27 | 0 | 1,233 | ||
| ZENDESK INC COM USD0.01 | COM | 98936J101 | 8,086 | 148,387 | SH | DFND | 29,177 | 0 | 119,210 | ||
| ZILLOW GROUP INC CL A | COM | 98954M101 | 24,203 | 405,075 | SH | DFND | 26,875 | 0 | 378,200 | ||
| ZILLOW GROUP INC CL C CAP STK | COM | 98954M200 | 55,893 | 946,371 | SH | DFND | 72,507 | 0 | 873,864 | ||
| ZOETIS INC COM USD0.01 CL A | COM | 98978V103 | 267 | 3,139 | SH | DFND | 68 | 0 | 3,071 | ||
| ZUORA INC COM CL A | COM | 98983V106 | 21,901 | 805,194 | SH | DFND | 82,947 | 0 | 722,247 | ||
| ZYNGA INC COM USD0.00000625 CLASS A | COM | 98986T108 | 11,420 | 2,806,005 | SH | DFND | 458,065 | 0 | 2,347,940 | ||