The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COMMON 002824100 17,634 294,299 SH   SOLE   294,299 0 0
ABIOMED INC COMMON 003654100 22,353 76,817 SH   SOLE   28,217 0 48,600
ACADIA PHARMACEUTICALS COMMON 004225108 17,604 783,424 SH   SOLE   429,329 0 354,095
ACCELERON PHARMA COMMON 00434H108 8,767 224,226 SH   SOLE   152,129 0 72,097
ACCURAY INC COMMON 004397105 1,923 384,547 SH   SOLE   0 0 384,547
ADAMAS PHARMACEUTI COMMON 00548A106 8,397 351,320 SH   SOLE   351,320 0 0
AERIE PHARMACEUTICALS COMMON 00771V108 29,220 538,618 SH   SOLE   319,518 0 219,100
ALBIREO PHARMA INC COMMON 01345P106 5,628 172,803 SH   SOLE   85,014 0 87,789
ALDER BIOPHARMACEUTICAL COMMON 014339105 10,968 863,600 SH   SOLE   541,500 0 322,100
ALEXION PHARM INC COMMON 015351109 10,700 96,000 SH   SOLE   96,000 0 0
AMICUS THERAPEUTICS COMMON 03152W109 51,219 3,405,541 SH   SOLE   1,962,984 0 1,442,557
APELLIS PHARMACEUTIC COMMON 03753U106 36,430 1,647,692 SH   SOLE   1,414,592 0 233,100
ARRAY BIOPHARMA INC COMMON 04269X105 16,837 1,031,650 SH   SOLE   584,450 0 447,200
AVEXIS INC COMMON 05366U100 2,734 22,120 SH   SOLE   22,120 0 0
BIOMARIN PHARMAC INC COMMON 09061G101 32,258 397,903 SH   SOLE   397,903 0 0
BRISTOL MYERS SQUIBB COMMON 110122108 9,690 153,200 SH   SOLE   153,200 0 0
CELGENE CORP COMMON 151020104 27,310 306,130 SH   SOLE   306,130 0 0
CIGNA CORP COMMON 125509109 9,936 59,237 SH   SOLE   59,237 0 0
CLEMENTIA PHARMACEUTICALS COMMON 185575107 1,700 112,213 SH   SOLE   112,213 0 0
CLOVIS ONCOLOGY COMMON 189464100 16,938 320,799 SH   SOLE   171,399 0 149,400
COLLEGIUM PHARMACEUTICAL COMMON 19459J104 31,593 1,236,534 SH   SOLE   785,366 0 451,168
DR REDDYS LABS LTD ADR 256135203 833 25,496 SH   SOLE   25,496 0 0
EDWARDS LIFESCIENCE COMMON 28176E108 18,132 129,959 SH   SOLE   129,959 0 0
ELI LILLY & CO COMMON 532457108 14,089 182,100 SH   SOLE   182,100 0 0
ESPERION THERAPEUTICS COMMON 29664W105 9,581 132,468 SH   SOLE   72,168 0 60,300
EVOLENT HEALTH INC COMMON 30050B101 6,035 423,482 SH   SOLE   1,030 0 422,452
EXACT SCIENCES CORP COMMON 30063P105 23,151 574,049 SH   SOLE   305,849 0 268,200
GILEAD SCIENCES INC COMMON 375558103 15,455 205,000 SH   SOLE   205,000 0 0
GLAUKOS CORP COMMON 377322102 10,149 329,199 SH   SOLE   155,299 0 173,900
GLOBAL BLOOD THERAPEUTICS COMMON 37890U108 9,032 186,994 SH   SOLE   104,541 0 82,453
HILL-ROM HLDS INC COMMON 431475102 7,673 88,200 SH   SOLE   0 0 88,200
HOMOLOGY MEDICINES COMMON 438083107 4,208 225,000 SH   SOLE   144,000 0 81,000
INCYTE CORPORATION COMMON 45337C102 6,603 79,245 SH   SOLE   79,245 0 0
INSULET CORP COMMON 45784P101 8,192 94,509 SH   SOLE   0 0 94,509
INTEC PHARMA LTD JER SHS M53644106 2,854 451,252 SH   SOLE   451,252 0 0
INTEGRA LIFESCIENCE COMMON 457985208 6,818 123,198 SH   SOLE   0 0 123,198
IRHYTHM TECHNOLOGIES COMMON 450056106 9,921 157,600 SH   SOLE   0 0 157,600
JOHNSON & JOHNSON COMMON 478160104 28,314 220,948 SH   SOLE   220,948 0 0
K2M GROUP HOLDINGS COMMON 48273J107 23,141 1,221,160 SH   SOLE   623,860 0 597,300
LA JOLLA PHARMACEUTICAL COMMON 503459604 33,598 1,128,219 SH   SOLE   748,075 0 380,144
MADRIGAL PHARMACEUTICALS COMMON 558868105 5,915 50,649 SH   SOLE   24,763 0 25,886
MASIMO CORP COMMON 574795100 6,403 72,800 SH   SOLE   0 0 72,800
MEDTRONIC PLC SHS G5960L103 18,017 224,600 SH   SOLE   224,600 0 0
MOLINA HEALTHCARE COMMON 60855R100 8,773 108,070 SH   SOLE   70 0 108,000
MOMENTA PHARMACEUTICALS COMMON 60877T100 4,804 264,699 SH   SOLE   0 0 264,699
NEKTAR THERAPEUTICS COMMON 640268108 10,511 98,914 SH   SOLE   65,114 0 33,800
NEUROCRINE BIOSCIENCES COMMON 64125C109 9,239 111,402 SH   SOLE   41,595 0 69,807
NEVRO CORP COMMON 64157F103 8,442 97,400 SH   SOLE   0 0 97,400
NOVARTIS AG SP ADR 66987V109 28,726 355,296 SH   SOLE   355,296 0 0
OBSEVA SA COMMON H5861P103 3,907 289,507 SH   SOLE   289,507 0 0
PFIZER INC COMMON 717081103 28,544 804,274 SH   SOLE   804,274 0 0
PORTOLA PHARMACEUTICALS COMMON 737010108 16,278 498,412 SH   SOLE   276,070 0 222,342
PRA HEALTH SCIENCE COMMON 69354M108 12,490 150,560 SH   SOLE   52,060 0 98,500
PTC THERAPEUTICS COMMON 69366J200 11,850 437,934 SH   SOLE   198,235 0 239,699
ROCKET PHARMACEUTICA COMMON 77313F106 4,053 216,158 SH   SOLE   216,158 0 0
SAGE THERAPEUTICS COMMON 78667J108 5,251 32,600 SH   SOLE   32,600 0 0
SAREPTA THERAPEUTICS COMMON 803607100 24,279 327,698 SH   SOLE   181,798 0 145,900
SAVARA INC COMMON 805111101 2,512 273,000 SH   SOLE   273,000 0 0
SIERRA ONCOLOGY INC COMMON 82640U107 417 201,660 SH   SOLE   201,660 0 0
SPRING BK PHARMACEUTICALS COMMON 849431101 2,025 131,656 SH   SOLE   131,656 0 0
TELADOC INC COMMON 87918A105 26,067 646,828 SH   SOLE   317,820 0 329,008
TESARO INC COMMON 881569107 12,871 225,260 SH   SOLE   124,560 0 100,700
UNITEDHEALTH GRP INC COMMON 91324P102 19,731 92,203 SH   SOLE   92,203 0 0
UNUM THERAPEUTICS COM USD 903214104 12,016 1,081,545 SH   SOLE   844,145 0 237,400
VERTEX PHARMACEUTICALS COMMON 92532F100 6,831 41,915 SH   SOLE   41,915 0 0
VIEWRAY INC COMMON 92672L107 7,329 1,139,863 SH   SOLE   545,368 0 594,495
WRIGHT MED GROUP N V ORD SHS N96617118 6,104 307,672 SH   SOLE   0 0 307,672
ZAI LAB LTD ADR 98887Q104 1,059 49,584 SH   SOLE   49,584 0 0