The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLION PHARMACEUTICALS COM 00448Q201 3,221 868,272 SH   SOLE 868,272 0 0
ADVAXIS INC COM NEW 007624208 1,178 697,000 SH   SOLE 697,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 7,203 132,770 SH   SOLE 132,770 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 5,820 610,738 SH   SOLE 610,738 0 0
ALDER BIOPHARMACEUTICALS INC NOTE 2.500% 2/0 014339AA3 227 250,000 PRN   SOLE 250,000 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 5,029 396,013 SH   SOLE 396,013 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 1,621 421,000 SH   SOLE 421,000 0 0
AQUINOX PHARMACEUTICALS INC COM 03842B101 1,520 107,928 SH   SOLE 107,928 0 0
ARCUS BIOSCIENCES INC COM 03969F109 116 7,500 SH   SOLE 7,500 0 0
ARDELYX INC COM 039697107 1,252 247,859 SH   SOLE 247,859 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 5,006 126,742 SH   SOLE 126,742 0 0
ARGENX SE SPONSORED ADR 04016X101 4,676 58,130 SH   SOLE 58,130 0 0
ARQULE INC COM 04269E107 1,397 484,984 SH   SOLE 484,984 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 5,183 79,245 SH   SOLE 79,245 0 0
ATRICURE INC COM 04963C209 7,985 389,145 SH   SOLE 389,145 0 0
BEIGENE LTD SPONSORED ADR 07725L102 1,231 7,330 SH   SOLE 7,330 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 4,649 974,652 SH   SOLE 974,652 0 0
BIONDVAX PHARMACEUTICALS LTD SPOND ADS 09073Q105 18 3,399 SH   SOLE 3,399 0 0
BIOTELEMETRY INC COM 090672106 2,158 69,500 SH   SOLE 69,500 0 0
BIOTIME INC COM 09066L105 489 181,600 SH   SOLE 181,600 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 8,133 88,691 SH   SOLE 88,691 0 0
CARA THERAPEUTICS INC COM 140755109 1,161 93,800 SH   SOLE 93,800 0 0
CIDARA THERAPEUTICS INC COM 171757107 93 23,132 SH   SOLE 23,132 0 0
CLEARSIDE BIOMEDICAL INC COM 185063104 54 5,000 SH   SOLE 5,000 0 0
CLEMENTIA PHARMACEUTICALS IN COM 185575107 1,591 105,000 SH   SOLE 105,000 0 0
COGENTIX MEDICAL INC COM 19243A104 1,195 310,382 SH   SOLE 310,382 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 4,207 323,843 SH   SOLE 323,843 0 0
DERMIRA INC COM 24983L104 607 76,000 SH   SOLE 76,000 0 0
DERMIRA INC NOTE 3.000% 5/1 24983LAA2 1,192 1,500,000 PRN   SOLE 1,500,000 0 0
DEXCOM INC COM 252131107 5,562 75,000 SH   SOLE 75,000 0 0
DEXCOM INC DBCV 0.750% 5/1 252131AE7 256 250,000 PRN   SOLE 250,000 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 1,721 335,500 SH   SOLE 335,500 0 0
GALAPAGOS NV SPON ADR 36315X101 3,951 39,609 SH   SOLE 39,609 0 0
GEMPHIRE THERAPEUTICS INC COM 36870A108 651 100,000 SH   SOLE 100,000 0 0
IMMUNE DESIGN CORP COM 45252L103 1,084 328,500 SH   SOLE 328,500 0 0
IMMUNOMEDICS INC COM 452907108 4,104 280,900 SH   SOLE 280,900 0 0
INCYTE CORP COM 45337C102 1,250 15,000 SH   SOLE 15,000 0 0
INOTEK PHARMACEUTICALS CORP NOTE 5.750% 8/0 45780VAB8 578 600,000 PRN   SOLE 600,000 0 0
INSULET CORP COM 45784P101 2,816 32,484 SH   SOLE 32,484 0 0
INSULET CORP NOTE 1.375% 45784PAG6 1,711 1,500,000 PRN   SOLE 1,500,000 0 0
IRONWOOD PHARMACEUTICALS INC DBCV 2.250% 6/1 46333XAD0 676 573,000 PRN   SOLE 573,000 0 0
ISHARES TR NASDAQ BIOTECH ETF 464287556 2,786 26,100 SH   SOLE 26,100 0 0
JOHNSON AND JOHNSON COM 478160104 1,205 9,400 SH   SOLE 9,400 0 0
KURA ONCOLOGY INC COM 50127T109 2,381 127,000 SH   SOLE 127,000 0 0
LEAP THERPEUTICS INC COM 52187K101 1,660 200,000 SH   SOLE 200,000 0 0
LOXO ONCOLOGY INC COM 548862101 20,944 181,537 SH   SOLE 181,537 0 0
LUMINEX CORP COM 55027E102 4,793 227,500 SH   SOLE 227,500 0 0
MACROGENICS INC COM 556099109 2,091 83,105 SH   SOLE 83,105 0 0
MASIMO CORPORATION COM 574795100 440 5,000 SH   SOLE 5,000 0 0
MINERVA NEUROSCIENCES INC COM 603380106 1,069 171,094 SH   SOLE 171,094 0 0
NATUS MEDICAL INC COM 639050103 1,275 37,900 SH   SOLE 37,900 0 0
NEOS THERAPEUTICS INC COM 64052L106 228 27,500 SH   SOLE 27,500 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 4,520 54,508 SH   SOLE 54,508 0 0
NXSTAGE MEDICAL INC COM 67072V103 7,610 306,119 SH   SOLE 306,119 0 0
OBSEVA SA COM H5861P103 92 6,785 SH   SOLE 6,785 0 0
PROQR THERAPEUTICS N V SHS EURO N71542109 710 230,770 SH   SOLE 230,770 0 0
PROTALIX BIOTHERAPEUTICS INC NOTE 4.500% 9/1 74365AAB7 2,125 2,500,000 PRN   SOLE 2,500,000 0 0
PROTEOSTASIS THERAPEUTICS IN COM 74373B109 1,269 267,100 SH   SOLE 267,100 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 4,000 4,000,000 PRN   SOLE 4,000,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 3,193 901,933 SH   SOLE 901,933 0 0
SAGE THERAPEUTICS INC COM 78667J108 15,141 94,000 SH   SOLE 94,000 0 0
SCPHARMACEUTICALS INC COM 810648105 692 55,844 SH   SOLE 55,844 0 0
SCYNEXIS INC COM 811292101 2,193 1,636,900 SH   SOLE 1,636,900 0 0
SIERRA ONCOLOGY INC COM 82640U107 166 79,969 SH   SOLE 79,969 0 0
SOL GEL TECHNOLOGIES LTD SHS M8694L103 361 35,000 SH   SOLE 35,000 0 0
SPERO THERAPEUTICS INC COM 84833T103 421 29,544 SH   SOLE 29,544 0 0
STEREOTAXIS INC COM 85916J409 9,096 13,680,554 SH   SOLE 13,680,554 0 0
SUNESIS PHARMACEUTICALS INC COM PAR 867328700 1,016 373,702 SH   SOLE 373,702 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 298 60,000 SH   SOLE 60,000 0 0
UNUM THERAPEUTICS INC COM 903214104 88 7,900 SH   SOLE 7,900 0 0
UROGEN PHARMA LTD COM M96088105 224 4,500 SH   SOLE 4,500 0 0
VBI VACCINES INC COM NEW 91822J103 3,493 998,000 SH   SOLE 998,000 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 1,780 44,400 SH   SOLE 44,400 0 0
XENON PHARMACEUTICALS INC COM 98420N105 1,851 377,695 SH   SOLE 377,695 0 0
ZOGENIX INC COM NEW 98978L204 3,775 94,264 SH   SOLE 94,264 0 0