Exhibit 99.1

Eyenovia Reports First Quarter 2018 Financial Results and Completion of EYN PG21 Study

New York, NY – May 9, 2018 – Eyenovia, Inc. (NASDAQ: EYEN), a clinical stage biopharmaceutical company developing a pipeline of ophthalmology products utilizing its patented piezo-print technology to deliver micro-therapeutics topically to the eye, today announced financial results for the first quarter ended March 31, 2018.

1Q 2018 Business Highlights

Dr. Sean Ianchulev, Eyenovia’s Chief Executive Officer and Chief Medical Officer commented, “We started 2018 with the successful completion of our initial public offering in January, which will help support our late stage clinical pipeline as we steadily advance 3 programs into Phase III development over the next 12 months. We also recently completed an ancillary clinical trial demonstrating the robust IOP lowering effect of our high-precision, piezo-print micro-dosing platform in 30 subjects (60 eyes). This clinical trial builds upon previously reported clinical data from our two Phase II studies in mydriasis and we intend to submit it for presentation to a major medical conference. We are preparing to submit two INDs by the end of 2018 as we move towards the initiation of the MicroStat Mydriasis Phase III program later this year and the MicroProst CACG Phase III program in the first half of 2019. Furthermore, we are encouraged by the FDA feedback to advance MicroPine for pediatric myopia into Phase III development, with the possibility of only one Phase III trial. With our robust pipeline and highly differentiated technology platform, we believe that our accomplished team is well positioned to execute on our outlined programs which have the potential to transform the field of ophthalmology and the way in which we treat front-of-the-eye conditions.”

First Quarter 2018 Financial Review

For the first quarter of 2018, net loss was approximately $(3.4) million, or $(0.45) per share, compared to a net loss of approximately $(1.1) million, or $(0.49) per share for the first quarter of 2017.

Research and development expenses totaled approximately $2.1 million for the first quarter of 2018, compared to approximately $0.9 million for the same period in 2017, an increase of 130%.

For the first quarter of 2018, general and administrative expenses were approximately $1.3 million, compared with approximately $0.2 million for the first quarter of 2017, an increase of 583%.

Total operating expenses for the first quarter of 2018 were approximately $3.4 million, compared to total operating expenses of approximately $1.1 million for the same period in 2017, an increase of 210%.

As of March 31, 2018, the Company’s cash balance was approximately $27.6 million compared to $5.2 million at December 31, 2017.

Completed initial public offering of 2,730,000 shares of common stock in January 2018. Eyenovia received $24.5 million in net proceeds after underwriting discounts and commissions and other estimated offering expenses.

The Company reiterated its anticipated 12-month key milestones:

Conference Call and Webcast

The conference call is scheduled to begin at 8:30 am ET on Wednesday, May 9, 2018. Participants should dial 1-866-916-2921 (United States) or 1-210-874-7771 (International) with the conference code 3097559. A live webcast of the conference call will also be available on the investor relations page of the Company's corporate website at www.eyenoviabio.com.

After the live webcast, the event will be archived on Eyenovia’s website for one year. In addition, a telephonic replay of the call will be available until May 16, 2018. The replay can be accessed by dialing 1-855-859-2056 (United States) or 1-404-537-3406 (International) with confirmation code 3097559.

About Eyenovia

Eyenovia, Inc. (NASDAQ: EYEN) is a specialty biopharmaceutical company building a portfolio of next generation topical eye treatments based on its proprietary delivery and formulation platform for micro-therapeutics. Eyenovia’s pipeline is currently focused on the late-stage development of micro-therapeutics for glaucoma and other eye diseases.

Forward Looking Statements

Except for historical information, all of the statements, expectations, and assumptions contained in this press release are forward-looking statements. Forward-looking statements include, but are not limited to, statements that express our intentions, beliefs, expectations, strategies, predictions or any other statements relating to our future activities or other future events or conditions. These statements are based on current expectations, estimates and projections about our business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Therefore, actual outcomes and results may, and are likely to, differ materially from what is expressed or forecasted in the forward-looking statements due to numerous factors discussed from time to time in documents which we file with the SEC. In addition, such statements could be affected by risks and uncertainties related to, among other things: risks involved in clinical trials, including, but not limited to, the initiation, timing, progress and results of such trials; the timing and our ability to submit applications for, obtain and maintain regulatory approvals for, our product candidates; our ability to implement our business plan to commercialize our product candidates; the potential advantages of our product candidates; the rate and degree of market acceptance and clinical utility of our product candidates; our estimates regarding the potential market opportunity for our product candidates; intellectual property risks; our current lack of commercialization, marketing and manufacturing capabilities and strategy; our ability to attract and retain key personnel; our ability to identify additional products, product candidates or technologies with significant commercial potential that are consistent with our commercial objectives; our expectations regarding our ability to fund our operating expenses and capital expenditure requirements; the impact of government laws and regulations; our competitive position; and general economic conditions. Any forward-looking statements speak only as of the date on which they are made, and except as may be required under applicable securities laws, we do not undertake any obligation to update any forward-looking statements.

Company Contact:

Eyenovia Inc.

John Gandolfo

Chief Financial Officer

jgandolfo@eyenoviabio.com

Investor Contact:

Tram Bui / Alexander Lobo

The Ruth Group

Phone: 646-536-7035/7037

E-mail: tbui@theruthgroup.com / alobo@theruthgroup.com

Media Contact:

The Ruth Group

Kirsten Thomas

508-280-6592

kthomas@theruthgroup.com

(Financial Statements to Follow)

EYENOVIA, INC.

Condensed Balance Sheets

EYENOVIA, INC.

Condensed Statements of Operations

(unaudited)