The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U INC COM USD0.001 | COM | 90214J101 | 217,314 | 2,586,147 | SH | DFND | 706,361 | 0 | 1,879,786 | ||
| ABIOMED INC | COM | 003654100 | 46,727 | 160,579 | SH | DFND | 55,708 | 0 | 104,871 | ||
| ABRAXAS PETE CORP | COM | 003830106 | 757 | 341,123 | SH | DFND | 48,374 | 0 | 292,749 | ||
| ACACIA COMMUNICATIONS INC COM | COM | 00401C108 | 19,900 | 517,418 | SH | DFND | 150,388 | 0 | 367,030 | ||
| ACADIA PHARMACEUTICALS INC COM | COM | 004225108 | 135 | 6,022 | SH | DFND | 3,286 | 0 | 2,736 | ||
| ACCELERATE DIAGNOSTICS INC COM USD0.001 | COM | 00430H102 | 1,977 | 86,532 | SH | DFND | 42,210 | 0 | 44,322 | ||
| ACM RESEARCH INC COM CL A | COM | 00108J109 | 693 | 56,350 | SH | DFND | 5,675 | 0 | 50,675 | ||
| ACTIVISION BLIZZARD INC COM | COM | 00507V109 | 51,041 | 756,609 | SH | DFND | 211,037 | 0 | 545,572 | ||
| ADESTO TECHNOLOGIES CORP COM | COM | 00687D101 | 12,150 | 1,641,930 | SH | DFND | 101,904 | 0 | 1,540,026 | ||
| ADOBE SYS INC | COM | 00724F101 | 91,684 | 424,304 | SH | DFND | 147,789 | 0 | 276,515 | ||
| ADVANCED MICRO DEVICES INC COM | COM | 007903107 | 261 | 26,004 | SH | DFND | 5,802 | 0 | 20,202 | ||
| ALASKA COMM SYS GRP INC | COM | 01167P101 | 4,376 | 2,430,882 | SH | DFND | 468,986 | 0 | 1,961,896 | ||
| ALIBABA GROUP HLDG LTD SPONSORED ADS | COM | 01609W102 | 82,780 | 451,018 | SH | DFND | 144,691 | 0 | 306,327 | ||
| ALIGN TECHNOLOGY INC COM | COM | 016255101 | 114,757 | 456,961 | SH | DFND | 54,221 | 0 | 402,740 | ||
| ALLEGIANT TRAVEL CO COM | COM | 01748X102 | 18,021 | 104,440 | SH | DFND | 8,077 | 0 | 96,363 | ||
| ALMOST FAMILY INC | COM | 020409108 | 11,665 | 208,307 | SH | DFND | 35,240 | 0 | 173,067 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 144,161 | 1,210,422 | SH | DFND | 322,000 | 0 | 888,422 | ||
| ALPHABET INC CAP STK CL A | COM | 02079K305 | 49,138 | 47,378 | SH | DFND | 4,882 | 0 | 42,496 | ||
| ALPHABET INC CAP STK CL C | COM | 02079K107 | 74,807 | 72,502 | SH | DFND | 8,730 | 0 | 63,772 | ||
| AMAZON.COM INC | COM | 023135106 | 438,186 | 302,753 | SH | DFND | 69,163 | 0 | 233,590 | ||
| AMBER ROAD INC COM USD0.001 | COM | 02318Y108 | 682 | 76,662 | SH | DFND | 10,369 | 0 | 66,293 | ||
| AMERICAN TOWER CORPORATION | COM | 03027X100 | 12,649 | 87,032 | SH | DFND | 8,357 | 0 | 78,675 | ||
| APACHE CORP | COM | 037411105 | 8,828 | 229,427 | SH | DFND | 27,365 | 0 | 202,062 | ||
| APPIAN CORP CL A | COM | 03782L101 | 6,203 | 246,340 | SH | DFND | 31,609 | 0 | 214,731 | ||
| APPLE INC | COM | 037833100 | 4,465 | 26,613 | SH | DFND | 7,025 | 0 | 19,588 | ||
| APPLIED MATERIALS INC | COM | 038222105 | 1,072 | 19,285 | SH | DFND | 7,434 | 0 | 11,851 | ||
| APPLIED OPTOELECTRONICS INC COM | COM | 03823U102 | 272 | 10,859 | SH | DFND | 845 | 0 | 10,014 | ||
| AQUANTIA CORP COM | COM | 03842Q108 | 27,311 | 1,739,583 | SH | DFND | 468,179 | 0 | 1,271,404 | ||
| ARISTA NETWORKS INC COM USD0.0001 | COM | 040413106 | 128,146 | 501,941 | SH | DFND | 30,313 | 0 | 471,628 | ||
| ASV HLDGS INC COM | COM | 00215L104 | 8,737 | 1,203,418 | SH | DFND | 126,486 | 0 | 1,076,932 | ||
| AT HOME GROUP INC COM | COM | 04650Y100 | 17,128 | 534,581 | SH | DFND | 60,098 | 0 | 474,483 | ||
| ATHENAHEALTH INC DELAWARE | COM | 04685W103 | 398 | 2,782 | SH | DFND | 281 | 0 | 2,501 | ||
| ATHENEX INC COM | COM | 04685N103 | 552 | 32,451 | SH | DFND | 17,659 | 0 | 14,792 | ||
| ATLASSIAN CORPORATION PLC COM USD0.1 CL A | COM | G06242104 | 21,292 | 394,887 | SH | DFND | 51,274 | 0 | 343,613 | ||
| AUTO TRADER GROUP PLC ORD GBP0.01 ISIN #GB00BVYVFW23 SEDOL #BVYV | COM | G06708104 | 4,875 | 991,170 | SH | DFND | 204,840 | 0 | 786,330 | ||
| AUTODESK INC COM | COM | 052769106 | 103,911 | 827,446 | SH | DFND | 134,161 | 0 | 693,285 | ||
| AVEXIS INC COM | COM | 05366U100 | 642 | 5,192 | SH | DFND | 1,767 | 0 | 3,425 | ||
| AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL # | COM | 05462W109 | 599 | 15,085 | SH | DFND | 15,000 | 0 | 85 | ||
| AXOGEN INC COM | COM | 05463X106 | 21,733 | 595,415 | SH | DFND | 122,861 | 0 | 472,554 | ||
| AZUL SA SPON ADR EACH REP 3 PFD SHS | COM | 05501U106 | 177,034 | 5,094,508 | SH | DFND | 951,617 | 0 | 4,142,891 | ||
| BANDWIDTH INC COM CL A | COM | 05988J103 | 2,450 | 75,018 | SH | DFND | 2,133 | 0 | 72,885 | ||
| BELLATRIX EXPLORATION LTD COM NPV ISIN #CA0783145075 SEDOL #BF23 | COM | 078314507 | 122 | 112,719 | SH | DFND | 21,794 | 0 | 90,925 | ||
| BIOSCRIP INC | COM | 09069N108 | 38,500 | 15,650,368 | SH | DFND | 3,910,773 | 0 | 11,739,595 | ||
| BLACK KNIGHT INC COM | COM | 09215C105 | 7,015 | 148,948 | SH | DFND | 3,622 | 0 | 145,326 | ||
| BLUEBIRD BIO INC COM | COM | 09609G100 | 26,106 | 152,893 | SH | DFND | 66,237 | 0 | 86,656 | ||
| BOINGO WIRELESS INC COM USD0.0001 | COM | 09739C102 | 3,815 | 154,003 | SH | DFND | 24,227 | 0 | 129,776 | ||
| BOSTON SCIENTIFIC CORP | COM | 101137107 | 1,185 | 43,359 | SH | DFND | 19,919 | 0 | 23,440 | ||
| BOX INC CL A | COM | 10316T104 | 7,299 | 355,173 | SH | DFND | 57,687 | 0 | 297,486 | ||
| BRIGHTCOVE INC COM USD0.001 | COM | 10921T101 | 208 | 29,872 | SH | DFND | 3,656 | 0 | 26,216 | ||
| BYD COMPANY LIMITED H CNY1 ISIN #CNE100000296 SEDOL #6536651 | COM | Y1023R104 | 32,270 | 4,138,366 | SH | DFND | 1,230,500 | 0 | 2,907,866 | ||
| C S X CORP | COM | 126408103 | 298 | 5,345 | SH | DFND | 123 | 0 | 5,222 | ||
| CAESARS ENTMT CORP COM | COM | 127686103 | 566 | 50,275 | SH | DFND | 37,590 | 0 | 12,685 | ||
| CALAMP CORP | COM | 128126109 | 5,530 | 241,702 | SH | DFND | 39,546 | 0 | 202,156 | ||
| CAMPING WORLD HLDGS INC CL A | COM | 13462K109 | 749 | 23,224 | SH | DFND | 9,076 | 0 | 14,148 | ||
| CANNAE HLDGS INC COM | COM | 13765N107 | 4,722 | 250,355 | SH | DFND | 65,331 | 0 | 185,024 | ||
| CARL ZEISS MEDITEC AG NPV ISIN #DE0005313704 SEDOL #5922961 | COM | D14895102 | 1,117 | 17,567 | SH | DFND | 6,430 | 0 | 11,137 | ||
| CARROLS RESTAURANT GROUP INC COM | COM | 14574X104 | 6,218 | 555,183 | SH | DFND | 79,095 | 0 | 476,088 | ||
| CARVANA CO CL A | COM | 146869102 | 8,398 | 366,249 | SH | DFND | 63,438 | 0 | 302,811 | ||
| CASA SYS INC COM | COM | 14713L102 | 662 | 22,552 | SH | DFND | 2,746 | 0 | 19,806 | ||
| CATAPULT GROUP INTERNATIONAL ISIN #AU000000CAT9 SEDOL #BTL0Y76 | COM | Q2159P101 | 206 | 225,166 | SH | DFND | 17,428 | 0 | 207,738 | ||
| CBS CORP NEW CL B | COM | 124857202 | 964 | 18,752 | SH | DFND | 4,556 | 0 | 14,196 | ||
| CD PROJEKT SA PLN1.00 ISIN #PLOPTTC00011 SEDOL #7302215 | COM | X0957E106 | 913 | 28,586 | SH | DFND | 15,241 | 0 | 13,345 | ||
| CHARTER COMMUNICATIONS INC NEW CL A | COM | 16119P108 | 618 | 1,986 | SH | DFND | 43 | 0 | 1,943 | ||
| CHEGG INC COM USD0.001 | COM | 163092109 | 142,656 | 6,904,917 | SH | DFND | 1,500,550 | 0 | 5,404,367 | ||
| CISION LTD COM USD0.0001 | COM | G1992S109 | 1,473 | 127,290 | SH | DFND | 51,043 | 0 | 76,247 | ||
| CITIGROUP INC COM NEW | COM | 172967424 | 7,947 | 117,738 | SH | DFND | 25,306 | 0 | 92,432 | ||
| CLOUDERA INC COM | COM | 18914U100 | 2,428 | 112,506 | SH | DFND | 25,949 | 0 | 86,557 | ||
| CODEXIS INC COM USD0.0001 | COM | 192005106 | 2,287 | 207,873 | SH | DFND | 106,435 | 0 | 101,438 | ||
| COGNEX CORP COM | COM | 192422103 | 30,835 | 593,090 | SH | DFND | 191,936 | 0 | 401,154 | ||
| CONSTELLATION BRANDS INC CL A | COM | 21036P108 | 11,182 | 49,062 | SH | DFND | 4,570 | 0 | 44,492 | ||
| CORIUM INTL INC COM | COM | 21887L107 | 7,146 | 622,986 | SH | DFND | 190,028 | 0 | 432,958 | ||
| COSTAMARE INC COM USD0.0001 | COM | Y1771G102 | 1,441 | 230,995 | SH | DFND | 0 | 0 | 230,995 | ||
| COUPA SOFTWARE INC COM | COM | 22266L106 | 8,774 | 192,324 | SH | DFND | 39,724 | 0 | 152,600 | ||
| COVANTA HLDG CORP COM | COM | 22282E102 | 7,700 | 531,056 | SH | DFND | 92,056 | 0 | 439,000 | ||
| CRIMSON WINE GROUP COM USD0.01 | COM | 22662X100 | 339 | 34,317 | SH | DFND | 772 | 0 | 33,545 | ||
| DEERE & COMPANY | COM | 244199105 | 16 | 100 | SH | DFND | 0 | 0 | 100 | ||
| DELIVERY HERO AG NPV 144A ISIN #DE000A2E4K43 SEDOL #BZCNB42 | COM | D1T0KZ103 | 601 | 12,510 | SH | DFND | 9,650 | 0 | 2,860 | ||
| DELTA AIR LINES INC DEL COM NEW | COM | 247361702 | 4,146 | 75,637 | SH | DFND | 1,043 | 0 | 74,594 | ||
| DENALI THERAPEUTICS INC COM | COM | 24823R105 | 269 | 13,683 | SH | DFND | 27 | 0 | 13,656 | ||
| DEXCOM INC | COM | 252131107 | 43,518 | 586,811 | SH | DFND | 82,505 | 0 | 504,306 | ||
| DIGI INTL INC COM | COM | 253798102 | 8,966 | 870,510 | SH | DFND | 148,777 | 0 | 721,733 | ||
| DOMINO S PIZZA ENTERPRISES L ISIN #AU000000DMP0 SEDOL #B07SFG7 | COM | Q32503106 | 20 | 616 | SH | DFND | 0 | 0 | 616 | ||
| ECO STIM ENERGY SOLUTIONS INC COM | COM | 27888D101 | 599 | 630,847 | SH | DFND | 61,513 | 0 | 569,334 | ||
| ECOSYNTHETIX INC COM ISIN #CA27923D1087 SEDOL #B4XBZ35 | COM | 27923D108 | 94 | 62,892 | SH | DFND | 7,325 | 0 | 55,567 | ||
| ELBIT SYSTEMS LTD ISIN #IL0010811243 SEDOL #6308913 | COM | M3760D101 | 42,965 | 353,419 | SH | DFND | 128,096 | 0 | 225,323 | ||
| ELECTRONIC ARTS | COM | 285512109 | 7,535 | 62,146 | SH | DFND | 3,134 | 0 | 59,012 | ||
| ENPHASE ENERGY INC COM USD0.00001 | COM | 29355A107 | 7,563 | 1,654,925 | SH | DFND | 296,329 | 0 | 1,358,596 | ||
| ENTERCOM COMMUNICATIONS CORP CL A | COM | 293639100 | 11,280 | 1,168,899 | SH | DFND | 374,441 | 0 | 794,458 | ||
| ENZO BIOCHEM INC | COM | 294100102 | 5,789 | 1,056,400 | SH | DFND | 308,856 | 0 | 747,544 | ||
| EPAM SYS INC COM USD0.001 | COM | 29414B104 | 69,217 | 604,407 | SH | DFND | 48,361 | 0 | 556,046 | ||
| EROS INTERNATIONAL COM GBP0.30 | COM | G3788M114 | 39,405 | 3,615,139 | SH | DFND | 949,873 | 0 | 2,665,266 | ||
| ESPERION THERAPEUTICS INC COM USD0.001 | COM | 29664W105 | 122 | 1,687 | SH | DFND | 204 | 0 | 1,483 | ||
| ETSY INC COM | COM | 29786A106 | 52,894 | 1,885,038 | SH | DFND | 196,394 | 0 | 1,688,644 | ||
| EVERBRIDGE INC COM | COM | 29978A104 | 17,619 | 481,396 | SH | DFND | 88,523 | 0 | 392,873 | ||
| EVOQUA WATER TECHNOLOGIES CORP COM | COM | 30057T105 | 1,642 | 77,143 | SH | DFND | 7,266 | 0 | 69,877 | ||
| EXACT SCIENCES CORP | COM | 30063P105 | 80,661 | 2,000,037 | SH | DFND | 367,982 | 0 | 1,632,055 | ||
| EXTRACTION OIL AND GAS INC COM | COM | 30227M105 | 8,620 | 752,224 | SH | DFND | 126,808 | 0 | 625,416 | ||
| EXXON MOBIL CORP | COM | 30231G102 | 104 | 1,400 | SH | DFND | 1,400 | 0 | 0 | ||
| FACEBOOK INC COM USD0.000006 CL A | COM | 30303M102 | 234,647 | 1,468,473 | SH | DFND | 468,233 | 0 | 1,000,240 | ||
| FANUC CORPORATION NPV ISIN #JP3802400006 SEDOL #6356934 | COM | J13440102 | 88 | 352 | SH | DFND | 227 | 0 | 125 | ||
| FB FINL CORP COM | COM | 30257X104 | 3,732 | 91,934 | SH | DFND | 19,262 | 0 | 72,672 | ||
| FIRST REP BK SAN FRANCISCO CAL COM | COM | 33616C100 | 30 | 319 | SH | DFND | 0 | 0 | 319 | ||
| FIVE BELOW INC COM | COM | 33829M101 | 78,489 | 1,070,202 | SH | DFND | 95,558 | 0 | 974,644 | ||
| FLEX LTD COM USD0.01 | COM | Y2573F102 | 2,860 | 175,111 | SH | DFND | 53,579 | 0 | 121,532 | ||
| FLEXION THERAPEUTICS INC COM | COM | 33938J106 | 82,900 | 3,699,242 | SH | DFND | 791,658 | 0 | 2,907,584 | ||
| FLOOR &DECOR HLDGS INC CL A | COM | 339750101 | 136,634 | 2,621,519 | SH | DFND | 471,848 | 0 | 2,149,671 | ||
| FORESCOUT TECHNOLOGIES INC COM | COM | 34553D101 | 28,676 | 883,983 | SH | DFND | 191,112 | 0 | 692,871 | ||
| FOUNDATION MEDICINE INC USD0.0001 | COM | 350465100 | 108,907 | 1,382,942 | SH | DFND | 398,669 | 0 | 984,273 | ||
| FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31 | COM | 351858105 | 5,901 | 86,288 | SH | DFND | 2,715 | 0 | 83,573 | ||
| FRESHPET INC COM | COM | 358039105 | 43,905 | 2,668,970 | SH | DFND | 305,637 | 0 | 2,363,333 | ||
| FRONTIER DEVELOPMENTS PLC GBP0.005 ISIN #GB00BBT32N39 SEDOL #BBT | COM | G36793100 | 2,910 | 157,763 | SH | DFND | 73,306 | 0 | 84,457 | ||
| FUSION TELECOMMUNICATIONS INTL INC COM NEW | COM | 36113B400 | 4,458 | 1,380,222 | SH | DFND | 404,030 | 0 | 976,192 | ||
| GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5 | COM | B44170106 | 20,856 | 208,592 | SH | DFND | 99,871 | 0 | 108,721 | ||
| GASLOG LTD COM USD0.01 | COM | G37585109 | 4,424 | 268,920 | SH | DFND | 47,052 | 0 | 221,868 | ||
| GEOPARK LIMITED COM USD0.001 | COM | G38327105 | 2,642 | 213,068 | SH | DFND | 458 | 0 | 212,610 | ||
| GILDAN ACTIVEWEAR INC COM ISIN #CA3759161035 SEDOL #2254645 | COM | 375916103 | 21 | 724 | SH | DFND | 0 | 0 | 724 | ||
| GLAUKOS CORP COM | COM | 377322102 | 40,372 | 1,309,491 | SH | DFND | 302,416 | 0 | 1,007,075 | ||
| GLOBANT SA USD1.20 | COM | L44385109 | 41,559 | 806,349 | SH | DFND | 236,768 | 0 | 569,581 | ||
| GLOBUS MED INC CL A NEW | COM | 379577208 | 8,552 | 171,661 | SH | DFND | 27,398 | 0 | 144,263 | ||
| GOLAR LNG LIMITED COM STK USD1.00 | COM | G9456A100 | 21,740 | 794,578 | SH | DFND | 202,332 | 0 | 592,246 | ||
| GOLD STD VENTURES CORP COM ISIN #CA3807381049 SEDOL #B05J9S2 | COM | 380738104 | 1,566 | 961,010 | SH | DFND | 104,700 | 0 | 856,310 | ||
| GRACE W R & CO DEL NEW | COM | 38388F108 | 15,029 | 245,451 | SH | DFND | 48,760 | 0 | 196,691 | ||
| GRUBHUB INC COM USD0.0001 | COM | 400110102 | 2,771 | 27,307 | SH | DFND | 5,214 | 0 | 22,093 | ||
| GRUPO FINANCIERO GALICIA SA ADR EACH REPR 10 CLASS B ARS1 LVL11 | COM | 399909100 | 27,227 | 414,033 | SH | DFND | 70,100 | 0 | 343,933 | ||
| GRUPO SUPERVIELLE S.A. SPON ADS EACH REP 5 ORD SHS CL B | COM | 40054A108 | 4,867 | 160,402 | SH | DFND | 29,508 | 0 | 130,894 | ||
| GTT COMMUNICATIONS INC COM USD0.0001 | COM | 362393100 | 109,227 | 1,926,397 | SH | DFND | 397,084 | 0 | 1,529,313 | ||
| GUIDEWIRE SOFTWARE INC COM USD0.0001 | COM | 40171V100 | 231 | 2,852 | SH | DFND | 2,060 | 0 | 792 | ||
| H &E EQUIPMENT SERVICES INC COM | COM | 404030108 | 3,287 | 85,402 | SH | DFND | 13,467 | 0 | 71,935 | ||
| HDFC BANK LTD ADS EACH REPR 3 INR10(MGT) | COM | 40415F101 | 47,098 | 476,849 | SH | DFND | 138,333 | 0 | 338,516 | ||
| HEALTHEQUITY INC COM | COM | 42226A107 | 4,767 | 78,740 | SH | DFND | 5,275 | 0 | 73,465 | ||
| HERC HLDGS INC COM | COM | 42704L104 | 97 | 1,500 | SH | DFND | 928 | 0 | 572 | ||
| HOMOLOGY MEDICINES INC COM | COM | 438083107 | 19 | 1,000 | SH | DFND | 0 | 0 | 1,000 | ||
| HUBSPOT INC COM | COM | 443573100 | 106,456 | 982,974 | SH | DFND | 103,151 | 0 | 879,823 | ||
| HUDSON LTD COM USD0.001 CL A | COM | G46408103 | 668 | 41,956 | SH | DFND | 30,171 | 0 | 11,785 | ||
| ICICI BANK LIMITED ADR EACH REPR 2 ORD INR10(SPON) | COM | 45104G104 | 2,904 | 328,115 | SH | DFND | 27,195 | 0 | 300,920 | ||
| IDORSIA LTD CHF0.05 ISIN #CH0363463438 SEDOL #BF0YK62 | COM | H3879B109 | 3,812 | 159,283 | SH | DFND | 27,940 | 0 | 131,343 | ||
| ILLUMINA INC COM | COM | 452327109 | 13,869 | 58,663 | SH | DFND | 6,123 | 0 | 52,540 | ||
| IMPINJ INC COM | COM | 453204109 | 12,492 | 959,462 | SH | DFND | 309,997 | 0 | 649,465 | ||
| INCYTE CORP COM | COM | 45337C102 | 132 | 1,588 | SH | DFND | 0 | 0 | 1,588 | ||
| INFINERA CORPORATION COM | COM | 45667G103 | 8,765 | 807,088 | SH | DFND | 135,002 | 0 | 672,086 | ||
| INPHI CORPORATION COM USD0.001 | COM | 45772F107 | 3,721 | 123,624 | SH | DFND | 31,007 | 0 | 92,617 | ||
| INSULET CORP COM | COM | 45784P101 | 1,121 | 12,927 | SH | DFND | 5,794 | 0 | 7,133 | ||
| INTERSECT ENT INC COM | COM | 46071F103 | 2,616 | 66,557 | SH | DFND | 18,236 | 0 | 48,321 | ||
| INTUITIVE SURGICAL INC COM NEW | COM | 46120E602 | 89,340 | 216,408 | SH | DFND | 20,042 | 0 | 196,366 | ||
| IPG PHOTONICS CORP COM | COM | 44980X109 | 1,694 | 7,258 | SH | DFND | 847 | 0 | 6,411 | ||
| IRHYTHM TECHNOLOGIES INC COM | COM | 450056106 | 8,411 | 133,610 | SH | DFND | 20,121 | 0 | 113,489 | ||
| JD COM INC SPONSORED ADR REPSTG COM CL A | COM | 47215P106 | 53,234 | 1,314,750 | SH | DFND | 412,476 | 0 | 902,274 | ||
| KANSAS CITY SOUTHERN COM | COM | 485170302 | 7,994 | 72,768 | SH | DFND | 7,815 | 0 | 64,953 | ||
| KORNIT DIGITAL LTD ORD ILS0.01 | COM | M6372Q113 | 14,324 | 1,110,367 | SH | DFND | 137,268 | 0 | 973,099 | ||
| LARSEN AND TOUBRO LTD GDR RP 1SH REG S ISIN #USY5217N1183 SEDOL | COM | ZZZ9952A4 | 2,913 | 144,923 | SH | DFND | 0 | 0 | 144,923 | ||
| LENDINGCLUB CORP COM | COM | 52603A109 | 399 | 114,094 | SH | DFND | 59,941 | 0 | 54,153 | ||
| LGI HOMES INC COM | COM | 50187T106 | 122,971 | 1,742,539 | SH | DFND | 301,591 | 0 | 1,440,948 | ||
| LHC GROUP INC COM | COM | 50187A107 | 2,750 | 44,674 | SH | DFND | 21,705 | 0 | 22,969 | ||
| LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP | COM | 531229706 | 5,108 | 224,743 | SH | DFND | 2,013 | 0 | 222,730 | ||
| LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP | COM | 531229888 | 16,846 | 738,227 | SH | DFND | 108,097 | 0 | 630,130 | ||
| LIBERTY MEDIA CORP DELAWARE COM C SIRIUSXM | COM | 531229607 | 167 | 4,085 | SH | DFND | 84 | 0 | 4,001 | ||
| LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA | COM | 531229854 | 26,321 | 853,196 | SH | DFND | 76,907 | 0 | 776,289 | ||
| LILIS ENERGY INC COM NEW | COM | 532403201 | 4,265 | 1,074,240 | SH | DFND | 269,107 | 0 | 805,133 | ||
| LIVEPERSON INC | COM | 538146101 | 51,231 | 3,133,383 | SH | DFND | 255,896 | 0 | 2,877,487 | ||
| LONZA GROUP AG-REG ISIN #CH0013841017 SEDOL #7333378 | COM | H50524133 | 26,985 | 114,746 | SH | DFND | 50,308 | 0 | 64,438 | ||
| LULULEMON ATHLETICA INC COM | COM | 550021109 | 193 | 2,165 | SH | DFND | 466 | 0 | 1,699 | ||
| LUMBER LIQUIDATORS HLDGS INC COM | COM | 55003T107 | 34,238 | 1,431,342 | SH | DFND | 511,380 | 0 | 919,962 | ||
| LUMENTUM HLDGS INC COM | COM | 55024U109 | 115,752 | 1,814,294 | SH | DFND | 318,810 | 0 | 1,495,484 | ||
| MADISON SQUARE GARDEN CO NEW CL A | COM | 55825T103 | 6,645 | 27,036 | SH | DFND | 5,265 | 0 | 21,771 | ||
| MAKEMYTRIP LTD USD0.0005 | COM | V5633W109 | 3,701 | 106,658 | SH | DFND | 25,162 | 0 | 81,496 | ||
| MARTIN MARIETTA MATLS INC | COM | 573284106 | 78,496 | 378,657 | SH | DFND | 38,409 | 0 | 340,248 | ||
| MASTERCARD INCORPORATED CL A | COM | 57636Q104 | 17,697 | 101,031 | SH | DFND | 21,362 | 0 | 79,669 | ||
| MATCH GROUP INC COM | COM | 57665R106 | 12,262 | 275,931 | SH | DFND | 46,186 | 0 | 229,745 | ||
| MEG ENERGY CORP COM ISIN #CA5527041084 SEDOL #B4XF9J1 | COM | 552704108 | 46 | 13,090 | SH | DFND | 3,600 | 0 | 9,490 | ||
| MERCADOLIBRE INC | COM | 58733R102 | 48,573 | 136,291 | SH | DFND | 34,357 | 0 | 101,934 | ||
| MERCURY SYS INC COM | COM | 589378108 | 25,982 | 537,715 | SH | DFND | 210,621 | 0 | 327,094 | ||
| METRO BANK PLC ORD GBP0.000001 ISIN #GB00BZ6STL67 SEDOL #BZ6STL6 | COM | G60640102 | 161,999 | 3,286,367 | SH | DFND | 641,993 | 0 | 2,644,374 | ||
| MICRON TECHNOLOGY | COM | 595112103 | 1,777 | 34,083 | SH | DFND | 12,873 | 0 | 21,210 | ||
| MICROSOFT CORP | COM | 594918104 | 53,069 | 581,448 | SH | DFND | 145,640 | 0 | 435,808 | ||
| MIMECAST LIMITED COM USD0.012 | COM | G14838109 | 1,200 | 33,866 | SH | DFND | 3,063 | 0 | 30,803 | ||
| MOHAWK INDS INC | COM | 608190104 | 310 | 1,337 | SH | DFND | 27 | 0 | 1,310 | ||
| MONGODB INC CL A | COM | 60937P106 | 62,184 | 1,432,808 | SH | DFND | 176,670 | 0 | 1,256,138 | ||
| MONOLITHIC PWR SYS INC COM | COM | 609839105 | 12,353 | 106,701 | SH | DFND | 10,788 | 0 | 95,913 | ||
| NEOPHOTONICS CORP COM | COM | 64051T100 | 61 | 8,890 | SH | DFND | 2,658 | 0 | 6,232 | ||
| NETFLIX COM INC COM | COM | 64110L106 | 589,905 | 1,997,308 | SH | DFND | 429,596 | 0 | 1,567,712 | ||
| NETGEAR INC | COM | 64111Q104 | 697 | 12,193 | SH | DFND | 790 | 0 | 11,403 | ||
| NETSHOES CAYMAN LTD COM USD0.0033 | COM | G6455X107 | 5,504 | 929,729 | SH | DFND | 344,201 | 0 | 585,528 | ||
| NEW HOME CO INC COM | COM | 645370107 | 342 | 30,911 | SH | DFND | 1,273 | 0 | 29,638 | ||
| NEW RELIC INC COM | COM | 64829B100 | 9,688 | 130,713 | SH | DFND | 24,327 | 0 | 106,386 | ||
| NEW YORK TIMES CO CL A | COM | 650111107 | 4,335 | 179,887 | SH | DFND | 43,737 | 0 | 136,150 | ||
| NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV | COM | 654445303 | 8,107 | 147,821 | SH | DFND | 26,347 | 0 | 121,474 | ||
| NINTENDO CO LTD NPV ISIN #JP3756600007 SEDOL #6639550 | COM | J51699106 | 643 | 1,466 | SH | DFND | 378 | 0 | 1,088 | ||
| NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST | COM | 65506L105 | 56 | 1,192 | SH | DFND | 0 | 0 | 1,192 | ||
| NRG ENERGY INC COM NEW | COM | 629377508 | 571 | 18,697 | SH | DFND | 407 | 0 | 18,290 | ||
| NUTANIX INC CL A | COM | 67059N108 | 1,775 | 36,140 | SH | DFND | 3,025 | 0 | 33,115 | ||
| NUVECTRA CORP COM | COM | 67075N108 | 15,616 | 1,199,416 | SH | DFND | 244,102 | 0 | 955,314 | ||
| NV5 GLOBAL INC COM | COM | 62945V109 | 9,543 | 171,172 | SH | DFND | 8,738 | 0 | 162,434 | ||
| NVIDIA CORP | COM | 67066G104 | 52,060 | 224,795 | SH | DFND | 83,428 | 0 | 141,367 | ||
| NXSTAGE MED INC COM | COM | 67072V103 | 329 | 13,237 | SH | DFND | 1,491 | 0 | 11,746 | ||
| OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74 | COM | G6718L106 | 126,824 | 17,032,324 | SH | DFND | 3,175,238 | 0 | 13,857,086 | ||
| OKTA INC CL A | COM | 679295105 | 30,365 | 761,980 | SH | DFND | 117,619 | 0 | 644,361 | ||
| ORASURE TECHNOLOGIES INC COM | COM | 68554V108 | 471 | 27,912 | SH | DFND | 2,880 | 0 | 25,032 | ||
| OVERSTOCK COM INC DEL COM | COM | 690370101 | 27,528 | 759,398 | SH | DFND | 163,180 | 0 | 596,218 | ||
| PALO ALTO NETWORKS INC COM USD0.0001 | COM | 697435105 | 1,702 | 9,378 | SH | DFND | 2,139 | 0 | 7,239 | ||
| PARAMOUNT RESOURCES LIMITED COM NPV CLASS A ISIN #CA6993202069 S | COM | 699320206 | 8,912 | 774,798 | SH | DFND | 88,581 | 0 | 686,217 | ||
| PAYPAL HLDGS INC COM | COM | 70450Y103 | 44,845 | 591,073 | SH | DFND | 172,208 | 0 | 418,865 | ||
| PDF SOLUTIONS INC | COM | 693282105 | 14,014 | 1,201,853 | SH | DFND | 106,854 | 0 | 1,094,999 | ||
| PENSKE AUTOMOTIVE GROUP INC | COM | 70959W103 | 3,355 | 75,688 | SH | DFND | 18,162 | 0 | 57,526 | ||
| PENUMBRA INC COM | COM | 70975L107 | 699 | 6,042 | SH | DFND | 1,596 | 0 | 4,446 | ||
| POLARITYTE INC COM | COM | 731094108 | 2,669 | 147,203 | SH | DFND | 80,917 | 0 | 66,286 | ||
| POOL CORP COM | COM | 73278L105 | 60,789 | 415,737 | SH | DFND | 65,859 | 0 | 349,878 | ||
| PROOFPOINT INC COM USD0.0001 | COM | 743424103 | 5,914 | 52,038 | SH | DFND | 3,797 | 0 | 48,241 | ||
| Q2 HLDGS INC COM | COM | 74736L109 | 15,875 | 348,525 | SH | DFND | 56,384 | 0 | 292,141 | ||
| QUANTERIX CORP COM | COM | 74766Q101 | 12,052 | 707,291 | SH | DFND | 207,518 | 0 | 499,773 | ||
| R1 RCM INC COM | COM | 749397105 | 3,647 | 510,761 | SH | DFND | 233,385 | 0 | 277,376 | ||
| REPUBLIC FIRST BANCORP INC COM | COM | 760416107 | 13,766 | 1,582,337 | SH | DFND | 723,414 | 0 | 858,923 | ||
| RIGHTMOVE PLC WINTERHILL SHS ISIN #GB00B2987V85 SEDOL #B2987V8 | COM | G75657109 | 21,485 | 352,332 | SH | DFND | 50,427 | 0 | 301,905 | ||
| RINGCENTRAL INC-CLASS A | COM | 76680R206 | 186,650 | 2,939,375 | SH | DFND | 591,546 | 0 | 2,347,829 | ||
| ROKU INC COM CL A | COM | 77543R102 | 56,471 | 1,815,788 | SH | DFND | 207,872 | 0 | 1,607,916 | ||
| ROYAL GOLD INC COM ISIN #US7802871084 SEDOL #2430553 | COM | 780287108 | 17 | 198 | SH | DFND | 0 | 0 | 198 | ||
| SAFETY INS GROUP INC | COM | 78648T100 | 390 | 5,074 | SH | DFND | 1,075 | 0 | 3,999 | ||
| SAILPOINT TECHNLGIES HLDGS INC COM | COM | 78781P105 | 30,318 | 1,465,345 | SH | DFND | 193,160 | 0 | 1,272,185 | ||
| SALESFORCE COM INC | COM | 79466L302 | 75,581 | 649,878 | SH | DFND | 195,272 | 0 | 454,606 | ||
| SANGAMO THERAPEUTICS INC COM | COM | 800677106 | 530 | 27,916 | SH | DFND | 7,213 | 0 | 20,703 | ||
| SAREPTA THERAPEUTICS INC COM | COM | 803607100 | 73,972 | 998,404 | SH | DFND | 255,808 | 0 | 742,596 | ||
| SCHNEIDER NATIONAL INC CL B | COM | 80689H102 | 2,284 | 87,635 | SH | DFND | 21,034 | 0 | 66,601 | ||
| SCIENTIFIC GAMES CORP COM | COM | 80874P109 | 3,592 | 86,339 | SH | DFND | 33,988 | 0 | 52,351 | ||
| SEA LIMITED ADS EACH REP ONE CLASS A ORD SHS | COM | 81141R100 | 27 | 2,424 | SH | DFND | 452 | 0 | 1,972 | ||
| SEASPAN CORPORATION COM STK USD0.01 | COM | Y75638109 | 2,002 | 299,628 | SH | DFND | 106,159 | 0 | 193,469 | ||
| SEASPINE HLDGS CORP COM | COM | 81255T108 | 3,454 | 340,610 | SH | DFND | 60,422 | 0 | 280,188 | ||
| SENESTECH INC COM | COM | 81720R109 | 699 | 1,370,911 | SH | DFND | 196,491 | 0 | 1,174,420 | ||
| SEQUANS COMMUNICATIONS SPON ADR EA REPR 1 ORD SHS | COM | 817323108 | 138 | 82,093 | SH | DFND | 11,651 | 0 | 70,442 | ||
| SERVICENOW INC COM USD0.001 | COM | 81762P102 | 24,894 | 150,460 | SH | DFND | 29,097 | 0 | 121,363 | ||
| SHAKE SHACK INC CL A | COM | 819047101 | 75,902 | 1,823,262 | SH | DFND | 289,634 | 0 | 1,533,628 | ||
| SHERWIN WILLIAMS CO | COM | 824348106 | 1,082 | 2,759 | SH | DFND | 59 | 0 | 2,700 | ||
| SHOPIFY INC COM NPV CL A ISIN #CA82509L1076 SEDOL #BX865C7 | COM | 82509L107 | 5,611 | 45,033 | SH | DFND | 11,968 | 0 | 33,065 | ||
| SHOTSPOTTER INC COM | COM | 82536T107 | 59,802 | 2,256,664 | SH | DFND | 534,815 | 0 | 1,721,849 | ||
| SIENTRA INC COM USD0.01 | COM | 82621J105 | 10,216 | 1,057,599 | SH | DFND | 187,452 | 0 | 870,147 | ||
| SIGNATURE BK NEW YORK N Y COM | COM | 82669G104 | 3,168 | 22,320 | SH | DFND | 4,150 | 0 | 18,170 | ||
| SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2 | COM | 828363101 | 5,700 | 3,167,300 | SH | DFND | 404,918 | 0 | 2,762,382 | ||
| SIMPLY GOOD FOODS CO COM | COM | 82900L102 | 275 | 20,006 | SH | DFND | 446 | 0 | 19,560 | ||
| SITEONE LANDSCAPE SUPPLY INC COM | COM | 82982L103 | 28,467 | 369,511 | SH | DFND | 48,480 | 0 | 321,031 | ||
| SIX FLAGS ENTMT CORP NEW COM | COM | 83001A102 | 7,195 | 115,568 | SH | DFND | 48,808 | 0 | 66,760 | ||
| SNAP INC CL A | COM | 83304A106 | 12,935 | 815,054 | SH | DFND | 290,581 | 0 | 524,473 | ||
| SOCIAL CAP HEDOSOPHIA HLDGS CORP UNIT 1 CL A & 1/3 WT EXP ISIN # | COM | G8250R111 | 1,981 | 187,415 | SH | DFND | 33,557 | 0 | 153,858 | ||
| SOLARIS OILFIELD INFRSTR INC COM CL A | COM | 83418M103 | 27,753 | 1,675,923 | SH | DFND | 199,384 | 0 | 1,476,539 | ||
| SONY CORP SPON ADR EACH REPR 1 ORD | COM | 835699307 | 67,365 | 1,393,557 | SH | DFND | 389,059 | 0 | 1,004,498 | ||
| SPARK THERAPEUTICS INC COM | COM | 84652J103 | 35,443 | 532,259 | SH | DFND | 203,532 | 0 | 328,727 | ||
| SPIRIT AIRLS INC COM | COM | 848577102 | 12,422 | 328,810 | SH | DFND | 35,849 | 0 | 292,961 | ||
| SPLUNK INC COM USD0.001 | COM | 848637104 | 5,235 | 53,204 | SH | DFND | 5,336 | 0 | 47,868 | ||
| SQUARE INC CL A | COM | 852234103 | 60,340 | 1,226,427 | SH | DFND | 147,164 | 0 | 1,079,263 | ||
| SS&C TECHNOLOGIES HLDGS INC COM | COM | 78467J100 | 47,682 | 888,922 | SH | DFND | 192,531 | 0 | 696,391 | ||
| STAMPS COM INC COM NEW | COM | 852857200 | 23 | 112 | SH | DFND | 88 | 0 | 24 | ||
| STAR BULK CARRIERS CORP COM USD0.01(POST REV SPLIT) | COM | Y8162K204 | 4,614 | 396,716 | SH | DFND | 75,438 | 0 | 321,278 | ||
| STITCH FIX INC COM CL A | COM | 860897107 | 18,361 | 905,384 | SH | DFND | 484 | 0 | 904,900 | ||
| SUMMIT MATLS INC CL A | COM | 86614U100 | 13,985 | 461,840 | SH | DFND | 49,671 | 0 | 412,169 | ||
| SUNOPTA INC COM ISIN #CA8676EP1086 SEDOL #2817510 | COM | 8676EP108 | 6,275 | 883,831 | SH | DFND | 158,311 | 0 | 725,520 | ||
| SUNRUN INC COM | COM | 86771W105 | 403 | 45,126 | SH | DFND | 4,882 | 0 | 40,244 | ||
| SVB FINL GROUP | COM | 78486Q101 | 6,471 | 26,962 | SH | DFND | 5,579 | 0 | 21,383 | ||
| T MOBILE US INC COM | COM | 872590104 | 51,106 | 837,257 | SH | DFND | 82,857 | 0 | 754,400 | ||
| TACTILE SYS TECHNOLOGY INC COM | COM | 87357P100 | 8,728 | 274,459 | SH | DFND | 47,122 | 0 | 227,337 | ||
| TAKE-TWO INTERACTIVE SOFTWARE COM | COM | 874054109 | 40,598 | 415,199 | SH | DFND | 133,337 | 0 | 281,862 | ||
| TAL EDUCATION GROUP SPON ADS EACH REP 0.3333 CL A ORD SHS | COM | 874080104 | 89,913 | 2,424,181 | SH | DFND | 487,472 | 0 | 1,936,709 | ||
| TALEND SA ADR EACH REP 1 ORD SHS | COM | 874224207 | 1,853 | 38,506 | SH | DFND | 8,021 | 0 | 30,485 | ||
| TELADOC INC COM | COM | 87918A105 | 56,176 | 1,393,957 | SH | DFND | 504,367 | 0 | 889,590 | ||
| TELESITES SAB DE CV COM NPV SER B-1 ISIN #MX01SI080038 SEDOL #BD | COM | P90355135 | 45 | 62,158 | SH | DFND | 23,883 | 0 | 38,275 | ||
| TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM | COM | G87572163 | 86,370 | 1,654,927 | SH | DFND | 500,432 | 0 | 1,154,495 | ||
| TERADYNE INC | COM | 880770102 | 6,620 | 144,834 | SH | DFND | 0 | 0 | 144,834 | ||
| TESLA INC COM | COM | 88160R101 | 175,994 | 661,307 | SH | DFND | 225,346 | 0 | 435,961 | ||
| TRANSDIGM GROUP INC COM | COM | 893641100 | 5,369 | 17,491 | SH | DFND | 154 | 0 | 17,337 | ||
| TSO3 INC COM ISIN #CA8730151013 SEDOL #2798518 | COM | 873015101 | 4,200 | 5,157,459 | SH | DFND | 486,121 | 0 | 4,671,338 | ||
| TWITTER INC COM USD0.000005 | COM | 90184L102 | 26,408 | 910,324 | SH | DFND | 107,206 | 0 | 803,118 | ||
| UBIQUITI NETWORKS INC COM USD0.001 | COM | 90347A100 | 108 | 1,577 | SH | DFND | 206 | 0 | 1,371 | ||
| ULTIMATE SOFTWARE GROUP INC | COM | 90385D107 | 2,856 | 11,719 | SH | DFND | 2,413 | 0 | 9,306 | ||
| UNITEDHEALTH GROUP | COM | 91324P102 | 101 | 470 | SH | DFND | 59 | 0 | 411 | ||
| USA TECHNOLOGIES INC COM NO PAR | COM | 90328S500 | 3,168 | 352,013 | SH | DFND | 184,192 | 0 | 167,821 | ||
| VANECK VECTORS ETF TR GOLD MINERS ETF | COM | 92189F106 | 15,472 | 703,935 | SH | DFND | 20,650 | 0 | 683,285 | ||
| VEEVA SYS INC CL A COM | COM | 922475108 | 9,869 | 135,161 | SH | DFND | 29,096 | 0 | 106,065 | ||
| VERIZON COMMUNICATIONS | COM | 92343V104 | 30,264 | 632,878 | SH | DFND | 213,677 | 0 | 419,201 | ||
| VOCERA COMMUNICATIONS INC COM | COM | 92857F107 | 6,887 | 294,057 | SH | DFND | 49,647 | 0 | 244,410 | ||
| W R BERKLEY CORPORATION COM | COM | 084423102 | 4,753 | 65,378 | SH | DFND | 17,940 | 0 | 47,438 | ||
| WALMART INC COM | COM | 931142103 | 108,216 | 1,216,316 | SH | DFND | 217,572 | 0 | 998,744 | ||
| WEIGHT WATCHERS INTL INC NEW | COM | 948626106 | 71,931 | 1,128,865 | SH | DFND | 113,427 | 0 | 1,015,438 | ||
| WHEATON PRECIOUS METALS CORP COM NPV ISIN #CA9628791027 SEDOL #B | COM | 962879102 | 1,798 | 88,273 | SH | DFND | 635 | 0 | 87,638 | ||
| WORKDAY INC COM USD0.001 CL A | COM | 98138H101 | 16,891 | 132,885 | SH | DFND | 27,925 | 0 | 104,960 | ||
| WORLD WRESTLING ENTERTAINMENT INC CL A | COM | 98156Q108 | 38,851 | 1,078,886 | SH | DFND | 109,534 | 0 | 969,352 | ||
| YANDEX N.V. COM USD0.01 CL A | COM | N97284108 | 297 | 7,522 | SH | DFND | 2,125 | 0 | 5,397 | ||
| ZAI LAB LTD-ADR | COM | 98887Q104 | 19,297 | 903,855 | SH | DFND | 339,325 | 0 | 564,530 | ||
| ZENDESK INC COM USD0.01 | COM | 98936J101 | 7,187 | 150,133 | SH | DFND | 29,177 | 0 | 120,956 | ||
| ZILLOW GROUP INC CL A | COM | 98954M101 | 22,234 | 411,732 | SH | DFND | 27,549 | 0 | 384,183 | ||
| ZILLOW GROUP INC CL C CAP STK | COM | 98954M200 | 51,311 | 953,745 | SH | DFND | 95,750 | 0 | 857,995 | ||
| ZOETIS INC COM USD0.01 CL A | COM | 98978V103 | 449 | 5,371 | SH | DFND | 117 | 0 | 5,254 | ||
| ZSCALER INC COM | COM | 98980G102 | 1,111 | 39,591 | SH | DFND | 95 | 0 | 39,496 | ||
| ZYNGA INC COM USD0.00000625 CLASS A | COM | 98986T108 | 10,600 | 2,896,140 | SH | DFND | 458,065 | 0 | 2,438,075 | ||