The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2U INC COM 90214J101 19,895 308,401 SH   SOLE   308,401 0 0
8X8 INC NEW COM 282914100 31,921 2,263,884 SH   SOLE   2,263,884 0 0
ABBOTT LABS COM 002824100 48,950 857,500 SH   SOLE   857,500 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 1,506 50,000 SH   SOLE   50,000 0 0
ACCELERON PHARMA INC COM 00434H108 43,713 1,030,000 SH   SOLE   1,030,000 0 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 54,201 354,045 SH   SOLE   354,045 0 0
ACHAOGEN INC COM 004449104 20,206 1,881,380 SH   SOLE   1,881,380 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 33,043 1,339,931 SH   SOLE   1,339,931 0 0
ACTIVISION BLIZZARD INC COM 00507V109 40,813 644,552 SH   SOLE   644,552 0 0
ADOBE SYS INC COM 00724F101 47,395 270,414 SH   SOLE   270,414 0 0
ADVANCED MICRO DEVICES INC COM 007903107 65,410 6,362,792 SH   SOLE   6,362,792 0 0
ADVANCED MICRO DEVICES INC COM 007903107 64,147 6,240,000 SH Call SOLE   6,240,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 5,975 100,000 SH   SOLE   100,000 0 0
AETNA INC NEW COM 00817Y108 8,148 45,122 SH   SOLE   45,122 0 0
AFFILIATED MANAGERS GROUP COM 008252108 43,049 209,738 SH   SOLE   209,738 0 0
AFLAC INC COM 001055102 20,562 234,250 SH   SOLE   234,250 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 2,863 250,000 SH   SOLE   250,000 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 67,735 566,371 SH   SOLE   566,371 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 96,064 557,138 SH   SOLE   557,138 0 0
ALIGN TECHNOLOGY INC COM 016255101 17,216 76,227 SH   SOLE   76,227 0 0
ALLEGHANY CORP DEL COM 017175100 63,454 106,450 SH   SOLE   106,450 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 65,587 516,232 SH   SOLE   516,232 0 0
ALPHABET INC CAP STK CL C 02079K107 303,460 290,004 SH   SOLE   290,004 0 0
ALPHABET INC CAP STK CL A 02079K305 160,799 152,648 SH   SOLE   152,648 0 0
ALTABA INC COM 021346101 36,358 520,520 SH   SOLE   520,520 0 0
ALTERYX INC COM CL A 02156B103 6,415 253,954 SH   SOLE   253,954 0 0
AMAZON COM INC COM 023135106 172,596 147,585 SH   SOLE   147,585 0 0
AMDOCS LTD SHS G02602103 53,645 819,257 SH   SOLE   819,257 0 0
AMETEK INC NEW COM 031100100 85,055 1,173,662 SH   SOLE   1,173,662 0 0
ANALOG DEVICES INC COM 032654105 2,107 23,661 SH   SOLE   23,661 0 0
ANAPTYSBIO INC COM 032724106 2,518 25,000 SH   SOLE   25,000 0 0
ANSYS INC COM 03662Q105 35,030 237,346 SH   SOLE   237,346 0 0
ANTHEM INC COM 036752103 160,541 713,468 SH   SOLE   713,468 0 0
AON PLC SHS CL A G0408V102 40,307 300,800 SH   SOLE   300,800 0 0
APPLE INC COM 037833100 281,690 1,664,248 SH   SOLE   1,664,248 0 0
APPLE INC COM 037833100 101,538 600,000 SH Call SOLE   600,000 0 0
APPLIED MATLS INC COM 038222105 42,479 830,882 SH   SOLE   830,882 0 0
APTIV PLC SHS G6095L109 7,523 88,679 SH   SOLE   88,679 0 0
ARCH CAP GROUP LTD ORD G0450A105 133,671 1,472,624 SH   SOLE   1,472,624 0 0
ARES CAP CORP COM 04010L103 11,270 716,732 SH   SOLE   716,732 0 0
ARISTA NETWORKS INC COM 040413106 24,967 105,960 SH   SOLE   105,960 0 0
ARRAY BIOPHARMA INC COM 04269X105 3,200 250,000 SH   SOLE   250,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 3,005 75,000 SH   SOLE   75,000 0 0
ASPEN TECHNOLOGY INC COM 045327103 4,964 74,988 SH   SOLE   74,988 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 6,801 150,300 SH   SOLE   150,300 0 0
ATLASSIAN CORP PLC CL A G06242104 4,854 106,640 SH   SOLE   106,640 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 10,419 2,300,000 SH   SOLE   2,300,000 0 0
AUTODESK INC COM 052769106 3,976 37,935 SH   SOLE   37,935 0 0
AVEO PHARMACEUTICALS INC COM 053588109 22,536 8,077,429 SH   SOLE   8,077,429 0 0
AXIS CAPITAL HOLDINGS LTD SHS G0692U109 15,078 300,000 SH   SOLE   300,000 0 0
AXON ENTERPRISE INC COM 05464C101 20,622 778,326 SH   SOLE   778,326 0 0
BAIDU INC SPON ADR REP A 056752108 49,054 209,514 SH   SOLE   209,514 0 0
BANK AMER CORP COM 060505104 90,547 3,067,104 SH   SOLE   3,067,104 0 0
BECTON DICKINSON & CO COM 075887109 16,483 77,000 SH   SOLE   77,000 0 0
BEIGENE LTD SPONSORED ADR 07725L102 7,818 80,000 SH   SOLE   80,000 0 0
BERKLEY W R CORP COM 084423102 63,124 881,000 SH   SOLE   881,000 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 138,883 700,650 SH   SOLE   700,650 0 0
BIO RAD LABS INC CL A 090572207 55,611 233,000 SH   SOLE   233,000 0 0
BIOGEN INC COM 09062X103 39,316 123,413 SH   SOLE   123,413 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 22,719 254,800 SH   SOLE   254,800 0 0
BIOMARIN PHARMACEUTICAL INC NOTE 0.599% 8/0 09061GAH4 7,007 7,000,000 SH   SOLE   7,000,000 0 0
BLACKSTONE GROUP L P COM UNIT LTD 09253U108 10,227 319,380 SH   SOLE   319,380 0 0
BLUEBIRD BIO INC COM 09609G100 3,117 17,500 SH   SOLE   17,500 0 0
BOOZ ALLEN HAMILTON HLDG COR CL A 099502106 40,334 1,057,790 SH   SOLE   1,057,790 0 0
BOSTON SCIENTIFIC CORP COM 101137107 8,106 327,000 SH   SOLE   327,000 0 0
BOX INC CL A 10316T104 41,190 1,950,263 SH   SOLE   1,950,263 0 0
BROADCOM LTD SHS Y09827109 12,869 50,013 SH   SOLE   50,013 0 0
BROWN & BROWN INC COM 115236101 51,431 999,431 SH   SOLE   999,431 0 0
CANADIAN NAT RES LTD COM 136385101 93,729 2,338,951 SH   SOLE   2,338,951 0 0
CARNIVAL CORP UNIT 99/99/9999 143658300 25,554 385,020 SH   SOLE   385,020 0 0
CASCADIAN THERAPEUTICS INC COM NEW 14740B606 7,030 1,900,000 SH   SOLE   1,900,000 0 0
CELGENE CORP COM 151020104 23,481 225,000 SH   SOLE   225,000 0 0
CENTENE CORP DEL COM 15135B101 41,113 407,500 SH   SOLE   407,500 0 0
CHUBB LIMITED COM H1467J104 159,052 1,088,377 SH   SOLE   1,088,377 0 0
CIGNA CORPORATION COM 125509109 34,525 170,000 SH   SOLE   170,000 0 0
CITIGROUP INC COM NEW 172967424 125,663 1,688,768 SH   SOLE   1,688,768 0 0
CITIZENS FINL GROUP INC COM 174610105 6,517 155,244 SH   SOLE   155,244 0 0
CITRIX SYS INC NOTE 0.500% 4/1 177376AD2 8,740 6,750,000 SH   SOLE   6,750,000 0 0
CLOUDERA INC COM 18914U100 25,393 1,537,115 SH   SOLE   1,537,115 0 0
COGNEX CORP COM 192422103 31,438 514,072 SH   SOLE   514,072 0 0
COPA HOLDINGS SA CL A P31076105 30,829 229,967 SH   SOLE   229,967 0 0
CORNING INC COM 219350105 6,174 193,003 SH   SOLE   193,003 0 0
CREE INC COM 225447101 16,126 434,200 SH   SOLE   434,200 0 0
CSG SYS INTL INC NOTE 4.250% 3/1 126349AF6 5,472 5,000,000 SH   SOLE   5,000,000 0 0
CYBERARK SOFTWARE LTD SHS M2682V108 19,124 462,144 SH   SOLE   462,144 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 2,300 250,000 SH   SOLE   250,000 0 0
DANAHER CORP DEL COM 235851102 16,947 182,560 SH   SOLE   182,560 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 5,668 250,000 SH   SOLE   250,000 0 0
DESPEGAR COM CORP ORD SHS G27358103 605 22,000 SH   SOLE   22,000 0 0
DISH NETWORK CORP NOTE 3.375% 8/1 25470MAB5 20,457 18,750,000 SH   SOLE   18,750,000 0 0
DOLBY LABORATORIES INC COM 25659T107 113,701 1,833,830 SH   SOLE   1,833,830 0 0
DYCOM INDS INC NOTE 0.750% 9/1 267475AB7 19,391 14,800,000 SH   SOLE   14,800,000 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 32,725 1,750,000 SH   SOLE   1,750,000 0 0
EAST WEST BANCORP INC COM 27579R104 4,321 71,027 SH   SOLE   71,027 0 0
EBAY INC COM 278642103 6,287 166,576 SH   SOLE   166,576 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 43,393 385,000 SH   SOLE   385,000 0 0
ELECTRONIC ARTS INC COM 285512109 24,338 231,625 SH   SOLE   231,625 0 0
EMERSON ELEC CO COM 291011104 3,577 51,326 SH   SOLE   51,326 0 0
ENTERPRISE FINL SVCS CORP COM 293712105 824 18,243 SH   SOLE   18,243 0 0
ESSENT GROUP LTD COM G3198U102 53,797 1,239,000 SH   SOLE   1,239,000 0 0
EVERBRIDGE INC COM 29978A104 27,973 941,221 SH   SOLE   941,221 0 0
EXELIXIS INC COM 30161Q104 15,200 500,000 SH   SOLE   500,000 0 0
EXPEDIA INC DEL COM NEW 30212P303 48,200 402,437 SH   SOLE   402,437 0 0
FACEBOOK INC CL A 30303M102 314,375 1,781,334 SH   SOLE   1,781,334 0 0
FIRST REP BK SAN FRANCISCO C COM 33616C100 11,112 128,271 SH   SOLE   128,271 0 0
FIVE9 INC COM 338307101 26,100 1,049,247 SH   SOLE   1,049,247 0 0
FLEX LTD ORD Y2573F102 48,481 2,694,913 SH   SOLE   2,694,913 0 0
FREEPORT-MCMORAN INC CL B 35671D857 36,155 1,906,905 SH   SOLE   1,906,905 0 0
GLYCOMIMETICS INC COM 38000Q102 11,406 679,336 SH   SOLE   679,336 0 0
HDFC BANK LTD ADR REPS 3 SHS 40415F101 2,537 24,951 SH   SOLE   24,951 0 0
HERITAGE INS HLDGS INC COM 42727J102 23,426 1,300,000 SH   SOLE   1,300,000 0 0
HMS HLDGS CORP COM 40425J101 3,132 185,000 SH   SOLE   185,000 0 0
HONEYWELL INTL INC COM 438516106 7,069 46,091 SH   SOLE   46,091 0 0
HUBSPOT INC COM 443573100 41,656 471,223 SH   SOLE   471,223 0 0
HUMANA INC COM 444859102 59,649 240,436 SH   SOLE   240,436 0 0
HUTCHISON CHINA MEDITECH LTD SPONSORED ADR 44842L103 1,154 30,000 SH   SOLE   30,000 0 0
IAC INTERACTIVECORP COM 44919P508 10,791 88,287 SH   SOLE   88,287 0 0
ICON PLC SHS G4705A100 33,794 301,330 SH   SOLE   301,330 0 0
ICU MED INC COM 44930G107 27,001 125,006 SH   SOLE   125,006 0 0
ILLUMINA INC COM 452327109 32,831 150,263 SH   SOLE   150,263 0 0
INCYTE CORP COM 45337C102 4,025 42,500 SH   SOLE   42,500 0 0
INPHI CORP COM 45772F107 3,256 88,930 SH   SOLE   88,930 0 0
INTERPUBLIC GROUP COS INC COM 460690100 28,551 1,416,216 SH   SOLE   1,416,216 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 3,326 9,115 SH   SOLE   9,115 0 0
J2 GLOBAL INC COM 48123V102 3,208 42,754 SH   SOLE   42,754 0 0
JELD-WEN HLDG INC COM 47580P103 30,225 767,729 SH   SOLE   767,729 0 0
JOHNSON & JOHNSON COM 478160104 171,426 1,226,752 SH   SOLE   1,226,752 0 0
JPMORGAN CHASE & CO COM 46625H100 89,795 839,240 SH   SOLE   839,240 0 0
JUNO THERAPEUTICS INC COM 48205A109 1,714 37,500 SH   SOLE   37,500 0 0
KEYCORP NEW COM 493267108 10,208 506,109 SH   SOLE   506,109 0 0
KIRBY CORP COM 497266106 54,944 822,512 SH   SOLE   822,512 0 0
KIRKLAND LAKE GOLD LTD COM 49741E100 0 2,501,907 SH   SOLE   2,501,907 0 0
KVH INDS INC COM 482738101 1,889 182,497 SH   SOLE   182,497 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 32,616 204,471 SH   SOLE   204,471 0 0
LAM RESEARCH CORP COM 512807108 3,960 21,510 SH   SOLE   21,510 0 0
LIBERTY EXPEDIA HOLDINGS SER A COM 53046P109 32,337 729,453 SH   SOLE   729,453 0 0
LIBERTY INTERACTIVE CORP QVC GP COM SER A 53071M104 13,884 568,563 SH   SOLE   568,563 0 0
LIBERTY INTERACTIVE CORP LBT VEN COM A NE 53071M856 38,574 711,177 SH   SOLE   711,177 0 0
LITTELFUSE INC COM 537008104 5,760 29,119 SH   SOLE   29,119 0 0
LOXO ONCOLOGY INC COM 548862101 40,558 481,800 SH   SOLE   481,800 0 0
LUMENTUM HLDGS INC COM 55024U109 22,446 459,178 SH   SOLE   459,178 0 0
MACQUARIE INFRASTRUCTURE COR NOTE 2.875% 7/1 55608BAA3 5,161 5,000,000 SH   SOLE   5,000,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 16,522 180,000 SH   SOLE   180,000 0 0
MAIN STREET CAPITAL CORP COM 56035L104 3,970 99,914 SH   SOLE   99,914 0 0
MANCHESTER UTD PLC NEW ORD CL A G5784H106 13,441 666,196 SH   SOLE   666,196 0 0
MARKEL CORP COM 570535104 138,419 121,513 SH   SOLE   121,513 0 0
MARSH & MCLENNAN COS INC COM 571748102 95,535 1,173,778 SH   SOLE   1,173,778 0 0
MASTERCARD INCORPORATED CL A 57636Q104 10,144 66,854 SH   SOLE   66,854 0 0
MATERIALISE NV SPONSORED ADS 57667T100 1,779 141,662 SH   SOLE   141,662 0 0
MEDIDATA SOLUTIONS INC COM 58471A105 24,895 392,851 SH   SOLE   392,851 0 0
MEDTRONIC PLC SHS G5960L103 43,193 534,892 SH   SOLE   534,892 0 0
MERCK & CO INC COM 58933Y105 17,136 304,266 SH   SOLE   304,266 0 0
META FINL GROUP INC COM 59100U108 5,156 55,698 SH   SOLE   55,698 0 0
MICROCHIP TECHNOLOGY INC COM 595017104 2,159 24,569 SH   SOLE   24,569 0 0
MICRON TECHNOLOGY INC COM 595112103 28,999 705,223 SH   SOLE   705,223 0 0
MICROSOFT CORP COM 594918104 271,448 3,172,392 SH   SOLE   3,172,392 0 0
MIMECAST LTD ORD SHS G14838109 33,395 1,164,793 SH   SOLE   1,164,793 0 0
MIX TELEMATICS LTD SPONSORED ADR 60688N102 4,339 340,867 SH   SOLE   340,867 0 0
MOHAWK INDS INC COM 608190104 58,691 212,724 SH   SOLE   212,724 0 0
MONGODB INC CL A 60937P106 594 20,000 SH   SOLE   20,000 0 0
MULESOFT INC CL A 625207105 7,378 317,206 SH   SOLE   317,206 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 1,494 200,000 SH   SOLE   200,000 0 0
NEKTAR THERAPEUTICS COM 640268108 60,780 1,017,776 SH   SOLE   1,017,776 0 0
NETEASE INC SPONSORED ADR 64110W102 35,404 102,605 SH   SOLE   102,605 0 0
NEW MTN FIN CORP COM 647551100 3,726 275,000 SH   SOLE   275,000 0 0
NEW RELIC INC COM 64829B100 43,712 756,724 SH   SOLE   756,724 0 0
NVIDIA CORP COM 67066G104 48,222 249,194 SH   SOLE   249,194 0 0
NXP SEMICONDUCTORS N V DBCV 1.000%12/0 62952QAB6 9,350 7,500,000 SH   SOLE   7,500,000 0 0
OMNICELL INC COM 68213N109 26,235 540,938 SH   SOLE   540,938 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 34,435 2,465,022 SH   SOLE   2,465,022 0 0
PACIFIC PREMIER BANCORP COM 69478X105 8,196 204,904 SH   SOLE   204,904 0 0
PAYPAL HLDGS INC COM 70450Y103 29,938 406,650 SH   SOLE   406,650 0 0
PEGASYSTEMS INC COM 705573103 24,100 511,127 SH   SOLE   511,127 0 0
PENNANTPARK FLOATING RATE CA COM 70806A106 9,396 685,000 SH   SOLE   685,000 0 0
PENUMBRA INC COM 70975L107 32,501 345,385 SH   SOLE   345,385 0 0
PERKINELMER INC COM 714046109 10,376 141,887 SH   SOLE   141,887 0 0
PFIZER INC COM 717081103 66,054 1,823,675 SH   SOLE   1,823,675 0 0
PNC FINL SVCS GROUP INC COM 693475105 15,684 108,667 SH   SOLE   108,667 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 28,633 588,200 SH   SOLE   588,200 0 0
POWERSHARES QQQ TRUST UNIT SER 1 73935A104 771,012 4,950,000 SH Put SOLE   4,950,000 0 0
PRA HEALTH SCIENCES INC COM 69354M108 54,574 599,294 SH   SOLE   599,294 0 0
PRICELINE GRP INC COM NEW 741503403 5,872 3,379 SH   SOLE   3,379 0 0
PROASSURANCE CORP COM 74267C106 22,146 387,500 SH   SOLE   387,500 0 0
PROGRESSIVE CORP OHIO COM 743315103 50,237 892,000 SH   SOLE   892,000 0 0
PROOFPOINT INC COM 743424103 29,443 331,528 SH   SOLE   331,528 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 1,040 50,000 SH   SOLE   50,000 0 0
PROTO LABS INC COM 743713109 9,897 96,085 SH   SOLE   96,085 0 0
PTC INC COM 69370C100 4,220 69,444 SH   SOLE   69,444 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 43,988 445,000 SH   SOLE   445,000 0 0
QUDIAN INC ADR 747798106 324 25,846 SH   SOLE   25,846 0 0
QUOTIENT LTD SHS G73268107 22,410 4,527,294 SH   SOLE   4,527,294 0 0
RA PHARMACEUTICALS INC COM 74933V108 1,063 125,000 SH   SOLE   125,000 0 0
RAPID7 INC COM 753422104 5,071 272,069 SH   SOLE   272,069 0 0
RED HAT INC COM 756577102 49,692 413,752 SH   SOLE   413,752 0 0
RED HAT INC NOTE 0.250%10/0 756577AD4 3,715 2,250,000 SH   SOLE   2,250,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 15,038 40,000 SH   SOLE   40,000 0 0
REINSURANCE GROUP AMER INC COM NEW 759351604 43,395 278,300 SH   SOLE   278,300 0 0
RENAISSANCERE HOLDINGS LTD COM G7496G103 42,135 335,500 SH   SOLE   335,500 0 0
RINGCENTRAL INC CL A 76680R206 26,599 549,569 SH   SOLE   549,569 0 0
RLI CORP COM 749607107 18,617 306,900 SH   SOLE   306,900 0 0
ROCKWELL AUTOMATION INC COM 773903109 3,410 17,366 SH   SOLE   17,366 0 0
ROPER TECHNOLOGIES INC COM 776696106 3,494 13,492 SH   SOLE   13,492 0 0
S&P GLOBAL INC COM 78409V104 79,987 472,180 SH   SOLE   472,180 0 0
SALESFORCE COM INC COM 79466L302 47,774 467,243 SH   SOLE   467,243 0 0
SAREPTA THERAPEUTICS INC COM 803607100 1,391 25,000 SH   SOLE   25,000 0 0
SCHWAB CHARLES CORP NEW COM 808513105 47,081 916,513 SH   SOLE   916,513 0 0
SELECT MED HLDGS CORP COM 81619Q105 31,308 1,773,847 SH   SOLE   1,773,847 0 0
SERVICENOW INC COM 81762P102 43,778 335,713 SH   SOLE   335,713 0 0
SHIRE PLC SPONSORED ADR 82481R106 4,654 30,000 SH   SOLE   30,000 0 0
SOLAR CAP LTD COM 83413U100 9,972 493,278 SH   SOLE   493,278 0 0
SPIRIT AIRLS INC COM 848577102 65,370 1,457,536 SH   SOLE   1,457,536 0 0
SPLUNK INC COM 848637104 39,966 482,510 SH   SOLE   482,510 0 0
SQUARE INC CL A 852234103 6,284 181,313 SH   SOLE   181,313 0 0
STERIS PLC SHS USD G84720104 28,549 326,384 SH   SOLE   326,384 0 0
STRYKER CORP COM 863667101 57,173 369,200 SH   SOLE   369,200 0 0
SUMMIT THERAPEUTICS PLC SPONS ADS 86627R102 1,108 100,000 SH   SOLE   100,000 0 0
SUNCOR ENERGY INC NEW COM 867224107 58,248 1,414,809 SH   SOLE   1,414,809 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 7,970 200,000 SH   SOLE   200,000 0 0
SVB FINL GROUP COM 78486Q101 10,931 46,761 SH   SOLE   46,761 0 0
SYNOPSYS INC COM 871607107 4,593 53,885 SH   SOLE   53,885 0 0
TABLEAU SOFTWARE INC CL A 87336U105 14,677 212,100 SH   SOLE   212,100 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADR 874039100 2,388 60,228 SH   SOLE   60,228 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 8,528 77,691 SH   SOLE   77,691 0 0
TELADOC INC COM 87918A105 25,665 736,446 SH   SOLE   736,446 0 0
TESARO INC COM 881569107 11,602 140,000 SH   SOLE   140,000 0 0
TESLA INC COM 88160R101 11,404 36,629 SH   SOLE   36,629 0 0
TESLA INC NOTE 0.250% 3/0 88160RAB7 2,113 2,000,000 SH   SOLE   2,000,000 0 0
TESLA INC NOTE 2.375% 3/1 88160RAD3 11,675 10,000,000 SH   SOLE   10,000,000 0 0
TEXAS INSTRS INC COM 882508104 25,055 239,857 SH   SOLE   239,857 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 3,763 19,819 SH   SOLE   19,819 0 0
TORONTO DOMINION BK ONT COM NEW 891160509 15,408 234,510 SH   SOLE   234,510 0 0
TRAVELERS COMPANIES INC COM 89417E109 45,575 336,000 SH   SOLE   336,000 0 0
TWILIO INC CL A 90138F102 1,942 82,293 SH   SOLE   82,293 0 0
UBS GROUP AG SHS H42097107 19,396 1,032,414 SH   SOLE   1,032,414 0 0
UNION PAC CORP COM 907818108 95,141 709,477 SH   SOLE   709,477 0 0
UNITED TECHNOLOGIES CORP COM 913017109 65,437 512,952 SH   SOLE   512,952 0 0
UNITEDHEALTH GROUP INC COM 91324P102 80,777 366,300 SH   SOLE   366,300 0 0
UNIVERSAL DISPLAY CORP COM 91347P105 33,247 192,651 SH   SOLE   192,651 0 0
US BANCORP DEL COM NEW 902973304 7,203 134,356 SH   SOLE   134,356 0 0
VALIDUS HOLDINGS LTD COM SHS G9319H102 137,336 2,927,026 SH   SOLE   2,927,026 0 0
VARIAN MED SYS INC COM 92220P105 14,258 128,245 SH   SOLE   128,245 0 0
VARONIS SYS INC COM 922280102 3,715 76,514 SH   SOLE   76,514 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 1,134 95,149 SH   SOLE   95,149 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 32,595 217,500 SH   SOLE   217,500 0 0
VISA INC COM CL A 92826C839 115,294 1,010,872 SH   SOLE   1,010,872 0 0
WELLS FARGO CO NEW COM 949746101 70,786 1,166,462 SH   SOLE   1,166,462 0 0
WORLD WRESTLING ENTMT INC CL A 98156Q108 19,229 633,687 SH   SOLE   633,687 0 0
XILINX INC COM 983919101 46,091 683,640 SH   SOLE   683,640 0 0
YAHOO INC NOTE 12/0 984332AF3 10,121 7,500,000 SH   SOLE   7,500,000 0 0
ZENDESK INC COM 98936J101 54,126 1,599,480 SH   SOLE   1,599,480 0 0