The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Adobe Systems Inc COM 00724F101 29,646 198,727 SH   SOLE 0 161,929 0 36,798
Adobe Systems Inc COM 00724F101 11,079 74,266 SH   DFND 1 74,266 0 0
Adobe Systems Inc COM 00724F101 90,038 603,550 SH   OTR 2 0 603,550 0
Alibaba Group Holding Ltd Sp A ADR 01609W102 105,614 611,512 SH   SOLE 0 493,036 0 118,476
Alibaba Group Holding Ltd Sp A ADR 01609W102 41,191 238,500 SH   DFND 1 238,500 0 0
Alibaba Group Holding Ltd Sp A ADR 01609W102 335,221 1,940,950 SH   OTR 2 0 1,940,950 0
Alphabet Inc Cl A COM 02079K305 102,230 104,989 SH   SOLE 0 85,243 0 19,746
Alphabet Inc Cl A COM 02079K305 39,478 40,543 SH   DFND 1 40,543 0 0
Alphabet Inc Cl A COM 02079K305 321,751 330,435 SH   OTR 2 0 330,435 0
Alphabet Inc Cl C COM 02079K107 109,781 114,461 SH   SOLE 0 92,615 0 21,846
Alphabet Inc Cl C COM 02079K107 42,633 44,451 SH   DFND 1 44,451 0 0
Alphabet Inc Cl C COM 02079K107 346,843 361,630 SH   OTR 2 0 361,630 0
Amazon Com Inc COM 023135106 187,171 194,696 SH   SOLE 0 157,508 0 37,188
Amazon Com Inc COM 023135106 71,996 74,890 SH   DFND 1 74,890 0 0
Amazon Com Inc COM 023135106 586,164 609,730 SH   OTR 2 0 609,730 0
Apple Inc COM 037833100 135,562 879,589 SH   SOLE 0 713,293 0 166,296
Apple Inc COM 037833100 51,699 335,444 SH   DFND 1 335,444 0 0
Apple Inc COM 037833100 419,717 2,723,310 SH   OTR 2 0 2,723,310 0
ASML Holding NV NY Registry COM N07059210 73,441 428,974 SH   SOLE 0 345,332 0 83,642
ASML Holding NV NY Registry COM N07059210 28,875 168,665 SH   DFND 1 168,665 0 0
ASML Holding NV NY Registry COM N07059210 234,595 1,370,300 SH   OTR 2 0 1,370,300 0
Automatic Data Process COM 053015103 27,130 248,165 SH   SOLE 0 201,754 0 46,411
Automatic Data Process COM 053015103 10,374 94,900 SH   DFND 1 94,900 0 0
Automatic Data Process COM 053015103 83,160 760,700 SH   OTR 2 0 760,700 0
Becton Dickinson & Co COM 075887109 54,193 276,565 SH   SOLE 0 223,813 0 52,752
Becton Dickinson & Co COM 075887109 21,427 109,350 SH   DFND 1 109,350 0 0
Becton Dickinson & Co COM 075887109 174,102 888,500 SH   OTR 2 0 888,500 0
Biogen Inc COM 09062X103 47,983 153,242 SH   SOLE 0 124,409 0 28,833
Biogen Inc COM 09062X103 18,145 57,950 SH   DFND 1 57,950 0 0
Biogen Inc COM 09062X103 147,630 471,480 SH   OTR 2 0 471,480 0
Boston Scientific Co COM 101137107 77,457 2,655,353 SH   SOLE 0 2,144,639 0 510,714
Boston Scientific Co COM 101137107 29,453 1,009,693 SH   DFND 1 1,009,693 0 0
Boston Scientific Co COM 101137107 239,088 8,196,350 SH   OTR 2 0 8,196,350 0
Broadcom Limited COM Y09827109 66,731 275,136 SH   SOLE 0 222,676 0 52,460
Broadcom Limited COM Y09827109 25,615 105,610 SH   DFND 1 105,610 0 0
Broadcom Limited COM Y09827109 208,330 858,950 SH   OTR 2 0 858,950 0
Celgene Corp COM 151020104 108,505 744,103 SH   SOLE 0 602,533 0 141,570
Celgene Corp COM 151020104 41,238 282,799 SH   DFND 1 282,799 0 0
Celgene Corp COM 151020104 335,603 2,301,490 SH   OTR 2 0 2,301,490 0
Charter Comm Inc COM 16119P108 73,303 201,703 SH   SOLE 0 161,662 0 40,041
Charter Comm Inc COM 16119P108 29,284 80,580 SH   DFND 1 80,580 0 0
Charter Comm Inc COM 16119P108 238,331 655,800 SH   OTR 2 0 655,800 0
Costar Group Inc COM 22160N109 43,755 163,113 SH   SOLE 0 132,244 0 30,869
Costar Group Inc COM 22160N109 16,616 61,942 SH   DFND 1 61,942 0 0
Costar Group Inc COM 22160N109 135,189 503,965 SH   OTR 2 0 503,965 0
Ctrip.com Intl Ltd American De ADR 22943F100 42,973 814,807 SH   SOLE 0 660,806 0 154,001
Ctrip.com Intl Ltd American De ADR 22943F100 16,362 310,240 SH   DFND 1 310,240 0 0
Ctrip.com Intl Ltd American De ADR 22943F100 133,139 2,524,450 SH   OTR 2 0 2,524,450 0
Ecolab Inc COM 278865100 54,536 424,044 SH   SOLE 0 341,313 0 82,731
Ecolab Inc COM 278865100 21,036 163,563 SH   DFND 1 163,563 0 0
Ecolab Inc COM 278865100 171,193 1,331,100 SH   OTR 2 0 1,331,100 0
Edwards Lifesciences COM 28176E108 39,918 365,180 SH   SOLE 0 295,481 0 69,699
Edwards Lifesciences COM 28176E108 15,142 138,525 SH   DFND 1 138,525 0 0
Edwards Lifesciences COM 28176E108 122,884 1,124,175 SH   OTR 2 0 1,124,175 0
Electronic Arts Inc COM 285512109 41,691 353,130 SH   SOLE 0 285,198 0 67,932
Electronic Arts Inc COM 285512109 16,172 136,980 SH   DFND 1 136,980 0 0
Electronic Arts Inc COM 285512109 131,596 1,114,650 SH   OTR 2 0 1,114,650 0
Expedia Inc COM 30212P303 81,173 563,935 SH   SOLE 0 455,827 0 108,108
Expedia Inc COM 30212P303 31,244 217,060 SH   DFND 1 217,060 0 0
Expedia Inc COM 30212P303 255,604 1,775,770 SH   OTR 2 0 1,775,770 0
Facebook Inc COM 30303M102 164,124 960,518 SH   SOLE 0 773,887 0 186,631
Facebook Inc COM 30303M102 64,162 375,500 SH   DFND 1 375,500 0 0
Facebook Inc COM 30303M102 522,093 3,055,500 SH   OTR 2 0 3,055,500 0
Fedex Corp COM 31428X106 49,282 218,469 SH   SOLE 0 174,308 0 44,161
Fedex Corp COM 31428X106 19,932 88,360 SH   DFND 1 88,360 0 0
Fedex Corp COM 31428X106 162,519 720,450 SH   OTR 2 0 720,450 0
Ferrari NV COM N3167Y103 41,199 372,905 SH   SOLE 0 301,786 0 71,119
Ferrari NV COM N3167Y103 15,846 143,430 SH   DFND 1 143,430 0 0
Ferrari NV COM N3167Y103 128,952 1,167,200 SH   OTR 2 0 1,167,200 0
Fidelity Natl Info Svcs COM 31620M106 46,151 494,175 SH   SOLE 0 400,093 0 94,082
Fidelity Natl Info Svcs COM 31620M106 17,685 189,370 SH   DFND 1 189,370 0 0
Fidelity Natl Info Svcs COM 31620M106 143,900 1,540,850 SH   OTR 2 0 1,540,850 0
Fiserv Inc COM 337738108 53,788 417,093 SH   SOLE 0 336,899 0 80,194
Fiserv Inc COM 337738108 20,870 161,830 SH   DFND 1 161,830 0 0
Fiserv Inc COM 337738108 169,537 1,314,650 SH   OTR 2 0 1,314,650 0
Fortive Corporation COM 34959J108 46,872 662,125 SH   SOLE 0 535,563 0 126,562
Fortive Corporation COM 34959J108 17,452 246,534 SH   DFND 1 246,534 0 0
Fortive Corporation COM 34959J108 142,040 2,006,500 SH   OTR 2 0 2,006,500 0
General Dynamics Corp COM 369550108 47,063 228,930 SH   SOLE 0 182,840 0 46,090
General Dynamics Corp COM 369550108 19,623 95,450 SH   DFND 1 95,450 0 0
General Dynamics Corp COM 369550108 159,725 776,950 SH   OTR 2 0 776,950 0
Hilton Worldwide Holding COM 43300A203 48,061 692,014 SH   SOLE 0 559,111 0 132,903
Hilton Worldwide Holding COM 43300A203 18,581 267,550 SH   DFND 1 267,550 0 0
Hilton Worldwide Holding COM 43300A203 151,186 2,176,900 SH   OTR 2 0 2,176,900 0
Home Depot Inc COM 437076102 69,644 425,801 SH   SOLE 0 344,269 0 81,532
Home Depot Inc COM 437076102 26,876 164,320 SH   DFND 1 164,320 0 0
Home Depot Inc COM 437076102 218,778 1,337,600 SH   OTR 2 0 1,337,600 0
Honeywell International COM 438516106 75,690 534,004 SH   SOLE 0 434,370 0 99,634
Honeywell International COM 438516106 29,231 206,230 SH   DFND 1 206,230 0 0
Honeywell International COM 438516106 237,921 1,678,575 SH   OTR 2 0 1,678,575 0
Illumina Inc COM 452327109 49,035 246,158 SH   SOLE 0 198,657 0 47,501
Illumina Inc COM 452327109 19,587 98,330 SH   DFND 1 98,330 0 0
Illumina Inc COM 452327109 159,360 800,000 SH   OTR 2 0 800,000 0
Intercontinental Exch COM 45866F104 52,760 767,981 SH   SOLE 0 619,071 0 148,910
Intercontinental Exch COM 45866F104 20,589 299,700 SH   DFND 1 299,700 0 0
Intercontinental Exch COM 45866F104 167,573 2,439,200 SH   OTR 2 0 2,439,200 0
Intuit COM 461202103 50,299 353,866 SH   SOLE 0 286,260 0 67,606
Intuit COM 461202103 19,351 136,140 SH   DFND 1 136,140 0 0
Intuit COM 461202103 157,512 1,108,150 SH   OTR 2 0 1,108,150 0
JD Com Inc Sp ADR Cl A ADR 47215P106 41,886 1,096,499 SH   SOLE 0 881,890 0 214,609
JD Com Inc Sp ADR Cl A ADR 47215P106 16,560 433,500 SH   DFND 1 433,500 0 0
JD Com Inc Sp ADR Cl A ADR 47215P106 134,506 3,521,100 SH   OTR 2 0 3,521,100 0
JPMorgan Chase & Co COM 46625H100 44,649 467,476 SH   SOLE 0 379,055 0 88,421
JPMorgan Chase & Co COM 46625H100 17,048 178,490 SH   DFND 1 178,490 0 0
JPMorgan Chase & Co COM 46625H100 138,404 1,449,100 SH   OTR 2 0 1,449,100 0
Lilly Eli & Co COM 532457108 70,195 820,612 SH   SOLE 0 663,449 0 157,163
Lilly Eli & Co COM 532457108 27,846 325,530 SH   DFND 1 325,530 0 0
Lilly Eli & Co COM 532457108 227,913 2,664,400 SH   OTR 2 0 2,664,400 0
Mastercard Inc COM 57636Q104 93,203 660,079 SH   SOLE 0 534,965 0 125,114
Mastercard Inc COM 57636Q104 35,551 251,780 SH   DFND 1 251,780 0 0
Mastercard Inc COM 57636Q104 289,340 2,049,150 SH   OTR 2 0 2,049,150 0
Microsoft Corp COM 594918104 146,870 1,971,683 SH   SOLE 0 1,593,963 0 377,720
Microsoft Corp COM 594918104 56,658 760,610 SH   DFND 1 760,610 0 0
Microsoft Corp COM 594918104 461,078 6,189,800 SH   OTR 2 0 6,189,800 0
Moodys Corp COM 615369105 45,979 330,287 SH   SOLE 0 267,100 0 63,187
Moodys Corp COM 615369105 17,696 127,120 SH   DFND 1 127,120 0 0
Moodys Corp COM 615369105 144,039 1,034,690 SH   OTR 2 0 1,034,690 0
Netflix Inc COM 64110L106 41,019 226,187 SH   SOLE 0 182,261 0 43,926
Netflix Inc COM 64110L106 16,073 88,630 SH   DFND 1 88,630 0 0
Netflix Inc COM 64110L106 130,790 721,200 SH   OTR 2 0 721,200 0
Nike Inc COM 654106103 48,890 942,903 SH   SOLE 0 763,830 0 179,073
Nike Inc COM 654106103 18,714 360,932 SH   DFND 1 360,932 0 0
Nike Inc COM 654106103 152,302 2,937,350 SH   OTR 2 0 2,937,350 0
Northrop Grumman Corp COM 666807102 38,204 132,783 SH   SOLE 0 105,463 0 27,320
Northrop Grumman Corp COM 666807102 16,354 56,840 SH   DFND 1 56,840 0 0
Northrop Grumman Corp COM 666807102 132,984 462,200 SH   OTR 2 0 462,200 0
Nvidia Corp COM 67066G104 47,741 267,053 SH   SOLE 0 216,526 0 50,527
Nvidia Corp COM 67066G104 18,217 101,900 SH   DFND 1 101,900 0 0
Nvidia Corp COM 67066G104 148,290 829,500 SH   OTR 2 0 829,500 0
Paypal Holdings Inc COM 70450Y103 55,882 872,734 SH   SOLE 0 704,001 0 168,733
Paypal Holdings Inc COM 70450Y103 21,774 340,060 SH   DFND 1 340,060 0 0
Paypal Holdings Inc COM 70450Y103 177,177 2,767,100 SH   OTR 2 0 2,767,100 0
Raytheon Co COM 755111507 51,215 274,496 SH   SOLE 0 219,894 0 54,602
Raytheon Co COM 755111507 21,125 113,220 SH   DFND 1 113,220 0 0
Raytheon Co COM 755111507 171,896 921,300 SH   OTR 2 0 921,300 0
Salesforce Com Inc COM 79466L302 135,986 1,455,635 SH   SOLE 0 1,172,667 0 282,968
Salesforce Com Inc COM 79466L302 53,313 570,685 SH   DFND 1 570,685 0 0
Salesforce Com Inc COM 79466L302 433,693 4,642,400 SH   OTR 2 0 4,642,400 0
Servicenow Inc COM 81762P102 61,069 519,606 SH   SOLE 0 420,679 0 98,927
Servicenow Inc COM 81762P102 23,388 198,996 SH   DFND 1 198,996 0 0
Servicenow Inc COM 81762P102 190,346 1,619,550 SH   OTR 2 0 1,619,550 0
Sherwin Williams Co COM 824348106 57,462 160,491 SH   SOLE 0 129,409 0 31,082
Sherwin Williams Co COM 824348106 22,288 62,250 SH   DFND 1 62,250 0 0
Sherwin Williams Co COM 824348106 181,234 506,185 SH   OTR 2 0 506,185 0
Skyworks Solutions Inc COM 83088M102 37,525 368,255 SH   SOLE 0 299,047 0 69,208
Skyworks Solutions Inc COM 83088M102 14,204 139,390 SH   DFND 1 139,390 0 0
Skyworks Solutions Inc COM 83088M102 115,590 1,134,350 SH   OTR 2 0 1,134,350 0
Splunk Inc COM 848637104 77,531 1,167,119 SH   SOLE 0 932,843 0 234,276
Splunk Inc COM 848637104 31,390 472,530 SH   DFND 1 472,530 0 0
Splunk Inc COM 848637104 254,816 3,835,850 SH   OTR 2 0 3,835,850 0
The Priceline Group Inc COM 741503403 93,401 51,016 SH   SOLE 0 43,350 0 7,666
The Priceline Group Inc COM 741503403 28,149 15,375 SH   DFND 1 15,375 0 0
The Priceline Group Inc COM 741503403 229,200 125,190 SH   OTR 2 0 125,190 0
Thermo Fisher Scientific COM 883556102 88,370 467,072 SH   SOLE 0 379,184 0 87,888
Thermo Fisher Scientific COM 883556102 34,459 182,130 SH   DFND 1 182,130 0 0
Thermo Fisher Scientific COM 883556102 280,366 1,481,850 SH   OTR 2 0 1,481,850 0
Union Pacific Corp COM 907818108 67,890 585,409 SH   SOLE 0 470,832 0 114,577
Union Pacific Corp COM 907818108 26,122 225,250 SH   DFND 1 225,250 0 0
Union Pacific Corp COM 907818108 212,214 1,829,900 SH   OTR 2 0 1,829,900 0
Unitedhealth Group Inc COM 91324P102 125,985 643,271 SH   SOLE 0 513,831 0 129,440
Unitedhealth Group Inc COM 91324P102 50,661 258,672 SH   DFND 1 258,672 0 0
Unitedhealth Group Inc COM 91324P102 412,225 2,104,800 SH   OTR 2 0 2,104,800 0
Visa Inc COM 92826C839 179,998 1,710,358 SH   SOLE 0 1,385,584 0 324,774
Visa Inc COM 92826C839 68,860 654,318 SH   DFND 1 654,318 0 0
Visa Inc COM 92826C839 560,329 5,324,300 SH   OTR 2 0 5,324,300 0
Zoetis Inc COM 98978V103 71,959 1,128,587 SH   SOLE 0 913,280 0 215,307
Zoetis Inc COM 98978V103 27,278 427,820 SH   DFND 1 427,820 0 0
Zoetis Inc COM 98978V103 222,003 3,481,850 SH   OTR 2 0 3,481,850 0
American Tower Corp REIT 03027X100 77,765 568,956 SH   SOLE 0 456,439 0 112,517
American Tower Corp REIT 03027X100 30,990 226,732 SH   DFND 1 226,732 0 0
American Tower Corp REIT 03027X100 251,430 1,839,550 SH   OTR 2 0 1,839,550 0
ABBVIE INC COM COM 00287Y109 1 6 SH   SOLE 0 6 0 0
ACTIVISION BLIZZARD INC COM 00507V109 2 29 SH   DFND 1 29 0 0
ADVANSIX INC COM COM 00773T101 2 41 SH   OTR 2 41 0 0
AIR PRODS & CHEMS INC COM COM 009158106 1 6 SH   SOLE 0 6 0 0
ALEXION PHARMACEUTICALS INC CO COM 015351109 2 17 SH   DFND 1 17 0 0
ALLERGAN PLC SHS COM G0177J108 5 25 SH   OTR 2 25 0 0
APPLIED MATLS INC COM COM 038222105 6 123 SH   SOLE 0 123 0 0
COMCAST CORP NEW CL A COM 20030N101 5 137 SH   DFND 1 137 0 0
COSTCO WHOLESALE CORP COM COM 22160K105 37 228 SH   OTR 2 228 0 0
CVS CORP COM COM 126650100 8 100 SH   SOLE 0 100 0 0
DANAHER CORP COM 235851102 35 410 SH   DFND 1 410 0 0
DELPHI AUTOMOTIVE PLC COM G27823106 7 75 SH   OTR 2 75 0 0
DELTA AIR LINES INC DEL COM NE COM 247361702 8 168 SH   SOLE 0 168 0 0
DEXCOM INC COM COM 252131107 40 811 SH   DFND 1 811 0 0
DIAMONDBACK ENERGY INC COM COM 25278X109 4 42 SH   OTR 2 42 0 0
DISNEY WALT CO COM DISNEY COM 254687106 8 84 SH   SOLE 0 84 0 0
DOLLAR TREE INC COM 256746108 2 20 SH   SOLE 0 20 0 0
EBAY INC COM COM 278642103 3 91 SH   SOLE 0 91 0 0
FLEETCOR TECHNOLOGIES INC COM COM 339041105 1 7 SH   SOLE 0 7 0 0
INTUITIVE SURGICAL INC COM NEW COM 46120E602 17 48 SH   SOLE 0 48 0 0
ISHARES TR RSSLL 1000 GRWT ETF-EQUITY 464287614 4,641 37,107 SH   SOLE 0 37,107 0 0
LOCKHEED MARTIN CORP COM COM 539830109 3 10 SH   SOLE 0 10 0 0
MEDTRONIC PLC COM G5960L103 18 235 SH   SOLE 0 235 0 0
MICRON TECHNOLOGY INC COM COM 595112103 10 265 SH   SOLE 0 265 0 0
MOBILEYE N V AMSTELVEEN ORD SH COM N51488117 0 255 SH   SOLE 0 255 0 0
NXP SEMICONDUCTORS N V COM COM N6596X109 3 23 SH   SOLE 0 23 0 0
O'REILLY AUTOMOTIVE INC NEW CO COM 67103H107 1 4 SH   SOLE 0 4 0 0
PEPSICO INC COM 713448108 11 103 SH   SOLE 0 103 0 0
QUINTILES TRANSNATIO HLDGS ICO COM 74876Y101 7 69 SH   SOLE 0 69 0 0
REGENERON PHARMACEUTICALS COM COM 75886F107 4 9 SH   SOLE 0 9 0 0
SOUTHWEST AIRLS CO COM COM 844741108 24 422 SH   SOLE 0 422 0 0
STARBUCKS CORP COM COM 855244109 31 574 SH   SOLE 0 574 0 0
STRYKER CORP COM COM 863667101 1 5 SH   SOLE 0 5 0 0
TIME WARNER INC COM COM 887317303 4 35 SH   SOLE 0 35 0 0
ULTA SALON COSMETCS & FRAG ICO COM 90384S303 2 10 SH   SOLE 0 10 0 0
UNDER ARMOUR INC CL C COM 904311206 0 2 SH   SOLE 0 2 0 0
VANGUARD INDEX TR GROWTH VIPER ETF-EQUITY 922908736 1 10 SH   SOLE 0 10 0 0
VERSUM MATLS INC COM COM 92532W103 0 3 SH   SOLE 0 3 0 0
XILINX INC COM COM 983919101 25 359 SH   SOLE 0 359 0 0