The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COMMON 003654100 21,694 128,671 SH   SOLE   59,272 0 69,399
ACADIA HEALTHCARE COMMON 00404A109 15,737 329,510 SH   SOLE   89,710 0 239,800
ACADIA PHARMACEUTICALS COMMON 004225108 30,980 822,392 SH   SOLE   369,356 0 453,036
ACCELERON PHARMA COMMON 00434H108 22,577 604,957 SH   SOLE   265,018 0 339,939
ACCURAY INC COMMON 004397105 2,750 687,547 SH   SOLE   900 0 686,647
AERIE PHARMACEUTICALS COMMON 00771V108 18,147 373,396 SH   SOLE   187,096 0 186,300
AGIOS PHARMACEUTICALS COMMON 00847X104 3,191 47,799 SH   SOLE   0 0 47,799
ALBIREO PHARMA INC COMMON 01345P106 3,311 158,027 SH   SOLE   158,027 0 0
AMICUS THERAPEUTICS COMMON 03152W109 36,386 2,412,870 SH   SOLE   1,194,496 0 1,218,374
BIOMARIN PHARMAC INC COMMON 09061G101 22,189 238,413 SH   SOLE   238,413 0 0
CELGENE CORP COMMON 151020104 18,801 128,932 SH   SOLE   128,932 0 0
CIGNA CORP COMMON 125509109 8,527 45,615 SH   SOLE   45,615 0 0
CLEMENTIA PHARMACEUT COMMON 185575107 512 30,313 SH   SOLE   30,313 0 0
CLOVIS ONCOLOGY COMMON 189464100 20,740 251,699 SH   SOLE   161,199 0 90,500
COLLEGIUM PHARMACEUTICAL COMMON 19459J104 18,352 1,749,457 SH   SOLE   1,102,980 0 646,477
DBV TECHNOLOGIES SPNS ADR 23306J101 2,241 52,799 SH   SOLE   52,799 0 0
DR REDDYS LABS LTD ADR 256135203 1,634 45,796 SH   SOLE   45,796 0 0
EDWARDS LIFESCIENCE COMMON 28176E108 14,492 132,580 SH   SOLE   132,580 0 0
ENVISION HEALTHCARE COMMON 29414D100 5,106 113,600 SH   SOLE   0 0 113,600
EVOLENT HEALTH INC COMMON 30050B101 11,618 652,680 SH   SOLE   256,828 0 395,852
EXACT SCIENCES CORP COMMON 30063P105 5,539 117,550 SH   SOLE   43,950 0 73,600
GILEAD SCIENCES INC COMMON 375558103 19,032 234,900 SH   SOLE   234,900 0 0
GLOBAL BLOOD THERAPEUTICS COMMON 37890U108 16,572 533,708 SH   SOLE   294,009 0 239,699
ILLUMINA INC COMMON 452327109 1,863 9,350 SH   SOLE   9,350 0 0
INCYTE CORPORATION COMMON 45337C102 3,939 33,745 SH   SOLE   33,745 0 0
INSMED INC COMMON 457669307 1,947 62,399 SH   SOLE   62,399 0 0
INTEC PHARMA LTD JER SHS M53644106 3,177 355,000 SH   SOLE   355,000 0 0
INTEGRA LIFESCIENCE COMMON 457985208 7,106 140,778 SH   SOLE   80 0 140,698
IRHYTHM TECHNOLOGIES COMMON 450056106 9,608 185,200 SH   SOLE   100 0 185,100
JOHNSON & JOHNSON COMMON 478160104 30,598 235,349 SH   SOLE   235,349 0 0
K2M GROUP HOLDINGS COMMON 48273J107 19,019 896,714 SH   SOLE   403,814 0 492,900
LA JOLLA PHARMACEUTICAL COMMON 503459604 20,920 601,500 SH   SOLE   352,276 0 249,224
LOXO ONCOLOGY INC COMMON 548862101 22,590 245,226 SH   SOLE   97,727 0 147,499
MASIMO CORP COMMON 574795100 6,302 72,800 SH   SOLE   0 0 72,800
MEDTRONIC PLC SHS G5960L103 21,866 281,160 SH   SOLE   281,160 0 0
MERCK & CO INC COMMON 58933Y105 20,828 325,280 SH   SOLE   325,280 0 0
MOLINA HEALTHCARE COMMON 60855R100 15,152 220,359 SH   SOLE   132,759 0 87,600
MOMENTA PHARMACEUTICALS COMMON 60877T100 6,891 372,499 SH   SOLE   0 0 372,499
NEUROCRINE BIOSCIENCES COMMON 64125C109 14,254 232,602 SH   SOLE   40,695 0 191,907
NEURODERM LTD ORD SHS M74231107 5,748 147,756 SH   SOLE   147,756 0 0
NOVARTIS AG SPNS ADR 66987V109 32,949 383,796 SH   SOLE   383,796 0 0
NUVASIVE INC COMMON 670704105 7,337 132,290 SH   SOLE   90 0 132,200
NXSTAGE MEDICAL COMMON 67072V103 2,721 98,579 SH   SOLE   335 0 98,244
OBSEVA SA COMMON H5861P103 1,732 212,831 SH   SOLE   212,831 0 0
PFIZER INC COMMON 717081103 34,189 957,673 SH   SOLE   957,673 0 0
PORTOLA PHARMACEUTICALS COMMON 737010108 27,362 506,414 SH   SOLE   274,372 0 232,042
PROTHENA CORP PLC SHS G72800108 12,689 195,909 SH   SOLE   102,709 0 93,200
PTC THERAPEUTICS I COMMON 69366J200 3,412 170,535 SH   SOLE   76,735 0 93,800
RA PHARMACEUTICALS COMMON 74933V108 4,060 278,082 SH   SOLE   87,200 0 190,882
REGENERON PHARMACEUTICALS COMMON 75886F107 14,718 32,917 SH   SOLE   32,917 0 0
SAREPTA THERAPEUTICS COMMON 803607100 3,134 69,099 SH   SOLE   69,099 0 0
SIERRA ONCOLOGY INC COMMON 82640U107 313 201,660 SH   SOLE   201,660 0 0
SPARK THERAPEUTICS COMMON 84652J103 10,396 116,599 SH   SOLE   49,900 0 66,699
SPRING BK PHARMACEUTICALS COMMON 849431101 2,078 123,383 SH   SOLE   123,383 0 0
TELADOC INC COMMON 87918A105 24,312 733,379 SH   SOLE   406,871 0 326,508
TESARO INC COMMON 881569107 19,339 149,799 SH   SOLE   92,100 0 57,699
TG THERAPEUTICS COMMON 88322Q108 1,189 100,366 SH   SOLE   100,366 0 0
TRILLIUM THERAPEUTCS COMMON 89620X506 1,206 234,248 SH   SOLE   234,248 0 0
UNITEDHEALTH GRP INC COMMON 91324P102 19,233 98,205 SH   SOLE   98,205 0 0
VERTEX PHARMACEUTICL COMMON 92532F100 5,169 34,000 SH   SOLE   34,000 0 0
WRIGHT MED GROUP N V ORD SHS N96617118 9,667 373,672 SH   SOLE   300 0 373,372
ZAI LAB LTD ADR 98887Q104 7,171 265,600 SH   SOLE   265,600 0 0