The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACLARIS THERAPEUTICS INC COM 00461U105 2,564 94,560 SH   SOLE   94,560 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 56 22,236 SH   SOLE   22,236 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 35,046 681,165 SH   SOLE   681,165 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 25,463 2,223,811 SH   SOLE   2,223,811 0 0
ALLERGAN PLC SHS G0177J108 292 1,200 SH   SOLE   1,200 0 0
AMEDISYS INC COM 023436108 211 3,356 SH   SOLE   3,356 0 0
AMICUS THERAPEUTICS INC COM 03152W109 121,282 12,043,932 SH   SOLE   12,043,932 0 0
ANTHEM INC COM 036752103 43,625 231,886 SH   SOLE   231,886 0 0
ARRAY BIOPHARMA INC COM 04269X105 134,705 16,093,786 SH   SOLE   16,093,786 0 0
ARRAY BIOPHARMA INC NOTE 3.000% 6/0 04269XAA3 25,656 19,000,000 PRN   SOLE   19,000,000 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 38,277 2,734,044 SH   SOLE   2,734,044 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 27,922 1,459,616 SH   SOLE   1,459,616 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 2,037 332,310 SH   SOLE   332,310 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 18,623 367,537 SH   SOLE   367,537 0 0
BOSTON SCIENTIFIC CORP COM 101137107 30,353 1,094,983 SH   SOLE   1,094,983 0 0
BROOKDALE SR LIVING INC COM 112463104 178 12,110 SH   SOLE   12,110 0 0
CASCADIAN THERAPEUTICS INC COM NEW 14740B606 13,879 3,735,994 SH   SOLE   3,735,994 0 0
CASTLIGHT HEALTH INC CL B 14862Q100 42 10,229 SH   SOLE   10,229 0 0
CATALENT INC COM 148806102 5,123 145,963 SH   SOLE   145,963 0 0
CENTENE CORP DEL COM 15135B101 31,808 398,200 SH   SOLE   398,200 0 0
CHIMERIX INC COM 16934W106 22,931 4,207,575 SH   SOLE   4,207,575 0 0
CLOVIS ONCOLOGY INC COM 189464100 14,232 152,000 SH Call SOLE   152,000 0 0
CLOVIS ONCOLOGY INC COM 189464100 71,570 764,389 SH   SOLE   764,389 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 10,825 698,392 SH   SOLE   698,392 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 25,776 218,000 SH   SOLE   218,000 0 0
EHEALTH INC COM 28238P109 22,999 1,223,334 SH   SOLE   1,223,334 0 0
ENDOLOGIX INC COM 29266S106 30,950 6,368,299 SH   SOLE   6,368,299 0 0
FATE THERAPEUTICS INC COM 31189P102 4,598 1,419,058 SH   SOLE   1,419,058 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 17,266 631,283 SH   SOLE   631,283 0 0
GLYCOMIMETICS INC COM 38000Q102 6,692 599,620 SH   SOLE   599,620 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 44,605 444,936 SH   SOLE   444,936 0 0
ICU MED INC COM 44930G107 22,857 132,505 SH   SOLE   132,505 0 0
IMMUNOGEN INC COM 45253H101 37,063 5,212,736 SH   SOLE   5,212,736 0 0
INC RESH HLDGS INC CL A 45329R109 49,223 841,418 SH   SOLE   841,418 0 0
INSMED INC COM PAR $.01 457669307 212 12,380 SH   SOLE   12,380 0 0
INVITAE CORP COM 46185L103 7,765 812,240 SH   SOLE   81,240 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 20,240 476,341 SH   SOLE   476,341 0 0
JOUNCE THERAPEUTICS INC COM 481116101 15,971 1,138,370 SH   SOLE   1,138,370 0 0
JUNO THERAPEUTICS INC COM 48205A109 66,344 2,219,616 SH   SOLE   2,219,616 0 0
LA JOLLA PHARMACEUTICAL CO COM PAR $.0001 2 503459604 21,234 713,280 SH   SOLE   713,280 0 0
LIVANOVA PLC SHS G5509L101 12,978 212,028 SH   SOLE   212,028 0 0
MEDPACE HLDGS INC COM 58506Q109 6,526 225,040 SH   SOLE   225,040 0 0
MODEL N INC COM 607525102 11,416 858,314 SH   SOLE   858,314 0 0
MOLINA HEALTHCARE INC COM 60855R100 57,321 828,574 SH   SOLE   828,574 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 14,337 866,819 SH   SOLE   866,819 0 0
NEKTAR THERAPEUTICS COM 640268108 285 14,580 SH   SOLE   14,580 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 305 6,640 SH   SOLE   6,640 0 0
NEURODERM LTD ORD SHS M74231107 16,597 555,096 SH   SOLE   555,096 0 0
NXSTAGE MEDICAL INC COM 67072V103 16,480 657,356 SH   SOLE   657,356 0 0
OVID THERAPEUTICS INC COM 690469101 4,237 448,781 SH   SOLE   448,781 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 36,263 2,155,949 SH   SOLE   2,155,949 0 0
PENUMBRA INC COM 70975L107 81,734 931,444 SH   SOLE   931,444 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109 8,301 1,596,275 SH   SOLE   1,596,275 0 0
PROTHENA CORP PLC SHS G72800108 27,585 509,698 SH   SOLE   509,698 0 0
PUMA BIOTECHNOLOGY INC CALL 74587V907 8,871 101,500 SH Call SOLE   101,500 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 75,204 860,456 SH   SOLE   860,456 0 0
REGENXBIO INC COM 75901B107 33,944 1,718,671 SH   SOLE   1,718,671 0 0
SEATTLE GENETICS INC COM 812578102 34,414 665,139 SH   SOLE   665,139 0 0
SPECTRANETICS CORP COM 84760C107 24,376 634,802 SH   SOLE   634,802 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 15,660 973,260 SH   SOLE   973,260 0 0
UNITEDHEALTH GROUP INC COM 91324P102 337 1,820 SH   SOLE   1,820 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 18,610 144,408 SH   SOLE   144,408 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 41,374 2,224,407 SH   SOLE   2,224,407 0 0
XENCOR INC COM 98401F105 25,068 1,187,494 SH   SOLE   1,187,494 0 0