The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COMMON 003654100 32,855 229,272 SH   SOLE   130,573 0 98,699
ACADIA HEALTHCARE COMMON 00404A109 29,787 603,210 SH   SOLE   356,810 0 246,400
ACADIA PHARMACEUTICALS COMMON 004225108 30,646 1,098,809 SH   SOLE   633,073 0 465,736
ACCELERON PHARMA COMMON 00434H108 18,371 604,499 SH   SOLE   294,560 0 309,939
ACCURAY INC COMMON 004397105 2,795 588,347 SH   SOLE   1,200 0 587,147
AERIE PHARMACEUTICALS COMMON 00771V108 21,161 402,674 SH   SOLE   208,474 0 194,200
AGIOS PHARMACEUTICALS COMMON 00847X104 6,359 123,599 SH   SOLE   40,100 0 83,499
ALBIREO PHARMA INC COMMON 01345P106 3,887 188,712 SH   SOLE   188,712 0 0
AMICUS THERAPEUTICS COMMON 03152W109 35,084 3,483,990 SH   SOLE   1,878,016 0 1,605,974
BIOMARIN PHARMAC INC COMMON 09061G101 28,461 313,382 SH   SOLE   313,382 0 0
CELGENE CORP COMMON 151020104 30,359 233,768 SH   SOLE   233,768 0 0
CIGNA CORP COMMON 125509109 2,596 15,510 SH   SOLE   15,510 0 0
CLOVIS ONCOLOGY COMMON 189464100 2,987 31,900 SH   SOLE   31,900 0 0
COLLEGIUM PHARMACEUTICAL COMMON 19459J104 22,627 1,808,750 SH   SOLE   1,242,258 0 566,492
DBV TECHNOLOGIES SP ADR 23306J101 6,398 179,152 SH   SOLE   70,399 0 108,753
DEXCOM INC COMMON 252131107 24,384 333,341 SH   SOLE   166,830 0 166,511
DR REDDYS LABS LTD ADR 256135203 803 19,065 SH   SOLE   19,065 0 0
EDWARDS LIFESCIENCE COMMON 28176E108 18,963 160,380 SH   SOLE   160,380 0 0
ENDO INTL PLC SHS G30401106 9,167 820,699 SH   SOLE   820,699 0 0
ENVISION HEALTHCARE COMMON 29414D100 8,349 133,220 SH   SOLE   220 0 133,000
EVOLENT HEALTH INC COMMON 30050B101 13,507 532,812 SH   SOLE   291,560 0 241,252
GLOBAL BLOOD THERAPEUTICS COMMON 37890U108 12,384 452,781 SH   SOLE   281,681 0 171,100
ILLUMINA INC COMMON 452327109 2,924 16,850 SH   SOLE   16,850 0 0
IMMUNE DESIGN CORP COMMON 45252L103 1,641 168,300 SH   SOLE   168,300 0 0
INCYTE CORPORATION COMMON 45337C102 2,751 21,845 SH   SOLE   21,845 0 0
INSMED INC COMMON 457669307 2,502 145,799 SH   SOLE   145,799 0 0
INTEGRA LIFESCIENCE COMMON 457985208 13,300 243,998 SH   SOLE   0 0 243,998
INTUITIVE SURGIC INC COMMON 46120E602 15,403 16,467 SH   SOLE   16,467 0 0
IRHYTHM TECHNOLOGIES COMMON 450056106 7,868 185,170 SH   SOLE   70 0 185,100
JOHNSON & JOHNSON COMMON 478160104 46,837 354,048 SH   SOLE   354,048 0 0
K2M GROUP HOLDINGS COMMON 48273J107 25,047 1,028,219 SH   SOLE   576,719 0 451,500
LA JOLLA PHARMACEUTICAL COMMON 503459604 17,563 589,959 SH   SOLE   352,335 0 237,624
LOXO ONCOLOGY INC COMMON 548862101 17,786 221,795 SH   SOLE   103,196 0 118,599
MASIMO CORP COMMON 574795100 6,683 73,300 SH   SOLE   0 0 73,300
MEDTRONIC PLC SHS G5960L103 35,354 398,360 SH   SOLE   398,360 0 0
MERCK & CO INC COMMON 58933Y105 46,753 729,483 SH   SOLE   729,483 0 0
MOMENTA PHARMACEUTICALS COMMON 60877T100 5,060 299,400 SH   SOLE   0 0 299,400
MYLAN N V SHS EURO N59465109 19,247 495,804 SH   SOLE   495,804 0 0
NEUROCRINE BIOSCIENCES COMMON 64125C109 10,981 238,707 SH   SOLE   56,395 0 182,312
NEURODERM LTD ORD SHS M74231107 10,468 350,085 SH   SOLE   350,085 0 0
NOVARTIS AG SP ADR 66987V109 46,684 559,296 SH   SOLE   559,296 0 0
NUVASIVE INC COMMON 670704105 30,252 393,289 SH   SOLE   219,389 0 173,900
NXSTAGE MEDICAL COMMON 67072V103 8,767 349,709 SH   SOLE   265 0 349,444
OBSEVA SA COMMON H5861P103 1,820 212,831 SH   SOLE   212,831 0 0
PFIZER INC COMMON 717081103 47,227 1,405,970 SH   SOLE   1,405,970 0 0
PORTOLA PHARMACEUTICALS COMMON 737010108 23,712 422,143 SH   SOLE   240,401 0 181,742
PROTHENA CORP PLC SHS G72800108 8,175 151,046 SH   SOLE   33,646 0 117,400
PTC THERAPEUTICS I COMMON 69366J200 1,113 60,735 SH   SOLE   60,735 0 0
RA PHARMACEUTICALS COMMON 74933V108 3,350 178,750 SH   SOLE   57,510 0 121,240
REGENERON PHARMACEUTICALS COMMON 75886F107 30,892 62,898 SH   SOLE   62,898 0 0
SAGE THERAPEUTICS COMMON 78667J108 972 12,199 SH   SOLE   12,199 0 0
SAREPTA THERAPEUTICS COMMON 803607100 971 28,799 SH   SOLE   28,799 0 0
SIERRA ONCOLOGY INC COMMON 82640U107 236 201,660 SH   SOLE   201,660 0 0
SPARK THERAPEUTICS COMMON 84652J103 6,052 101,300 SH   SOLE   57,400 0 43,900
SPRING BK PHARMACEUTICALS COMMON 849431101 1,523 112,500 SH   SOLE   112,500 0 0
TELADOC INC COMMON 87918A105 18,845 543,073 SH   SOLE   314,165 0 228,908
TEVA PHARMACEUTICAL SP ADR 881624209 20,008 602,279 SH   SOLE   602,279 0 0
TG THERAPEUTICS COMMON 88322Q108 817 81,266 SH   SOLE   81,266 0 0
TRILLIUM THERAPEUTICS COMMON 89620X506 806 183,272 SH   SOLE   183,272 0 0
VERSARTIS INC COMMON 92529L102 1,828 104,757 SH   SOLE   104,757 0 0
WRIGHT MED GROUP N V ORD SHS N96617118 10,271 373,622 SH   SOLE   250 0 373,372