The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abbott Laboratories COM 002824100 4,618 95,000 SH   SOLE   0 0 95,000
AbbVie Inc COM 00287Y109 9,789 135,000 SH   SOLE   0 0 135,000
Abiomed Inc COM 003654100 15,211 106,150 SH   SOLE   0 0 106,150
Acadia Pharmaceuticals Inc COM 004225108 837 30,000 SH   SOLE   0 0 30,000
Achillion Pharmaceuticals Inc COM 00448Q201 762 166,000 SH   SOLE   0 0 166,000
Adamas Pharmaceuticals Inc COM 00548A106 6,439 368,166 SH   SOLE   0 0 368,166
Adverum Biotechnologies Inc COM 00773U108 385 154,006 SH   SOLE   0 0 154,006
Aerie Pharmaceuticals Inc COM 00771V108 3,941 75,000 SH   SOLE   0 0 75,000
Aetna Inc COM 00817Y108 5,618 37,000 SH   SOLE   0 0 37,000
Alexion Pharmaceuticals Inc COM 015351109 18,737 154,000 SH   SOLE   0 0 154,000
Alkermes Plc SHS G01767105 7,850 135,409 SH   SOLE   0 0 135,409
Allergan Plc SHS G0177J108 12,641 52,000 SH   SOLE   0 0 52,000
Alnylam Pharmaceuticals Inc COM 02043Q107 6,396 80,190 SH   SOLE   0 0 80,190
AmerisourceBergen Corp COM 03073E105 4,254 45,000 SH   SOLE   0 0 45,000
Amgen Inc COM 031162100 6,028 35,000 SH   SOLE   0 0 35,000
Anheuser-Busch InBev SA ADR spons repr 1 Share COM 03524A108 310 2,806 SH   SOLE   0 0 2,806
Anthem Inc COM 036752103 4,979 26,468 SH   SOLE   0 0 26,468
Anthera Pharmaceuticals Inc Reg COM 03674U300 41 25,000 SH   SOLE   0 0 25,000
Array BioPharma Inc COM 04269X105 3,557 425,000 SH   SOLE   0 0 425,000
Biogen Inc COM 09062X103 13,161 48,500 SH   SOLE   0 0 48,500
BioMarin Pharmaceutical Inc COM 09061G101 17,192 189,300 SH   SOLE   0 0 189,300
Bioverativ Inc Reg S COM 09075E100 1,865 31,000 SH   SOLE   0 0 31,000
Bristol Myers Squibb Co COM 110122108 6,330 113,595 SH   SOLE   0 0 113,595
Cardinal Health Inc COM 14149Y108 4,286 55,000 SH   SOLE   0 0 55,000
Catabasis Pharmaceuticals Inc COM 14875P107 441 310,756 SH   SOLE   0 0 310,756
Celgene Corp COM 151020104 18,442 142,000 SH   SOLE   0 0 142,000
Centene Corp COM 15135B101 7,988 100,000 SH   SOLE   0 0 100,000
Chimerix Inc COM 16934W106 2,180 400,000 SH   SOLE   0 0 400,000
Cigna Corp COM 125509109 7,533 45,000 SH   SOLE   0 0 45,000
Coherus BioSciences Inc COM 19249H103 2,423 168,872 SH   SOLE   0 0 168,872
Concert Pharm Inc COM 206022105 420 30,099 SH   SOLE   0 0 30,099
CVS Health Corp COM 126650100 6,839 85,000 SH   SOLE   0 0 85,000
DaVita Inc COM 23918K108 3,562 55,000 SH   SOLE   0 0 55,000
Dexcom Inc COM 252131107 7,635 104,380 SH   SOLE   0 0 104,380
Dynavax Technologies Corp COM 268158201 5,668 587,330 SH   SOLE   0 0 587,330
Edwards Lifesciences Corp COM 28176E108 3,902 33,000 SH   SOLE   0 0 33,000
Eli Lilly & Co COM 532457108 12,345 150,000 SH   SOLE   0 0 150,000
Endo International Plc SHS G30401106 3,097 277,303 SH   SOLE   0 0 277,303
Endologix Inc COM 29266S106 7,655 1,575,000 SH   SOLE   0 0 1,575,000
Epizyme Inc COM 29428V104 3,807 252,136 SH   SOLE   0 0 252,136
Esperion Therapeutics Inc COM 29664W105 16,816 363,347 SH   SOLE   0 0 363,347
Exelixis Inc COM 30161Q104 25,862 1,050,000 SH   SOLE   0 0 1,050,000
Express Scripts Hg Co COM 30219G108 9,959 156,000 SH   SOLE   0 0 156,000
Exxon Mobil Corp COM 30231G102 389 4,823 SH   SOLE   0 0 4,823
FibroGen Inc COM 31572Q808 4,985 154,341 SH   SOLE   0 0 154,341
Ford Motor Co COM 345370860 318 28,404 SH   SOLE   0 0 28,404
Forward Pharma A/S spons ADS Level III repr 1 Share COM 34986J105 744 36,584 SH   SOLE   0 0 36,584
Gilead Sciences Inc COM 375558103 18,185 256,916 SH   SOLE   0 0 256,916
Glaukos Corp COM 377322102 14,326 345,450 SH   SOLE   0 0 345,450
Halliburton Co (Hg Co) COM 406216101 330 7,718 SH   SOLE   0 0 7,718
Halozyme Therapeutics Inc COM 40637H109 1,538 120,000 SH   SOLE   0 0 120,000
HCA Healthcare Inc COM 40412C101 8,258 94,707 SH   SOLE   0 0 94,707
Hologic Inc COM 436440101 3,177 70,000 SH   SOLE   0 0 70,000
Horizon Pharma Plc SHS G4617B105 28,750 2,422,090 SH   SOLE   0 0 2,422,090
Humana Inc COM 444859102 8,422 35,000 SH   SOLE   0 0 35,000
IBM Corp COM 459200101 272 1,766 SH   SOLE   0 0 1,766
Immunomedics Inc COM 452907108 4,676 529,610 SH   SOLE   0 0 529,610
Incyte Corp Ltd COM 45337C102 17,633 140,046 SH   SOLE   0 0 140,046
Insulet Corp COM 45784P101 1,796 35,000 SH   SOLE   0 0 35,000
Intercept Pharmaceuticals Inc COM 45845P108 364 3,008 SH   SOLE   0 0 3,008
Intra-Cellular Therapies Inc COM 46116X101 10,348 833,154 SH   SOLE   0 0 833,154
Iovance Biotherapeutics Inc Reg COM 462260100 4,778 650,000 SH   SOLE   0 0 650,000
Jazz Pharmaceuticals Plc SHS G50871105 13,221 85,020 SH   SOLE   0 0 85,020
JPMorgan Chase & Co COM 46625H100 442 4,837 SH   SOLE   0 0 4,837
Keryx Biopharmaceuticals Inc COM 492515101 3,074 425,111 SH   SOLE   0 0 425,111
Kite Pharma Inc COM 49803L109 6,220 60,000 SH   SOLE   0 0 60,000
Laboratory Corp of America Hgs COM 50540R409 3,083 20,000 SH   SOLE   0 0 20,000
Livanova Plc SHS G5509L101 6,234 101,854 SH   SOLE   0 0 101,854
Macrogenics Inc COM 556099109 3,064 175,000 SH   SOLE   0 0 175,000
Medtronic Plc SHS G5960L103 16,961 191,115 SH   SOLE   0 0 191,115
Merck & Co Inc COM 58933Y105 8,973 140,000 SH   SOLE   0 0 140,000
Microsoft Corp COM 594918104 330 4,793 SH   SOLE   0 0 4,793
Mirati Therapeutics Inc COM 60468T105 183 50,000 SH   SOLE   0 0 50,000
Nektar Therapeutics COM 640268108 15,542 795,000 SH   SOLE   0 0 795,000
Neurocrine Biosciences Inc COM 64125C109 5,520 120,000 SH   SOLE   0 0 120,000
NeuroDerm Ltd SHS M74231107 13,803 461,654 SH   SOLE   0 0 461,654
Nevro Corp COM 64157F103 11,545 155,118 SH   SOLE   0 0 155,118
NovoCure Ltd Reg SHS G6674U108 21,042 1,216,314 SH   SOLE   0 0 1,216,314
NxStage Medical Inc COM 67072V103 5,362 213,901 SH   SOLE   0 0 213,901
Ocular Therapeutix Inc COM 67576A100 371 40,000 SH   SOLE   0 0 40,000
Omnicell Inc COM 68213N109 4,061 94,231 SH   SOLE   0 0 94,231
Ophthotech Corp COM 683745103 61 23,920 SH   SOLE   0 0 23,920
Orexigen Therapeutics Inc COM 686164302 348 120,000 SH   SOLE   0 0 120,000
Pfizer Inc COM 717081103 14,458 430,422 SH   SOLE   0 0 430,422
Portola Pharmaceuticals Inc COM 737010108 6,224 110,805 SH   SOLE   0 0 110,805
Qualcomm Inc COM 747525103 296 5,368 SH   SOLE   0 0 5,368
Radius Health Inc COM 750469207 3,392 75,000 SH   SOLE   0 0 75,000
Regeneron Pharmaceuticals Inc COM 75886F107 7,416 15,100 SH   SOLE   0 0 15,100
Regulus Therapeutic Inc COM 75915K101 585 593,629 SH   SOLE   0 0 593,629
Revance Therapeutics Inc COM 761330109 5,808 220,000 SH   SOLE   0 0 220,000
Rigel Pharmaceuticals Inc COM 766559603 3,756 1,375,900 SH   SOLE   0 0 1,375,900
Rite Aid Corp COM 767754104 1,033 350,000 SH   SOLE   0 0 350,000
Sage Therapeutics Inc COM 78667J108 3,982 50,000 SH   SOLE   0 0 50,000
Sanofi spons ADR repr 0.5 Share COM 80105N105 7,666 160,000 SH   SOLE   0 0 160,000
Staar Surgical Co COM 852312305 755 69,950 SH   SOLE   0 0 69,950
Supernus Pharmaceuticals Inc COM 868459108 1,293 30,000 SH   SOLE   0 0 30,000
Tandem Diabetes Care Inc COM 875372104 187 234,000 SH   SOLE   0 0 234,000
Tetraphase Pharmaceuticals Inc COM 88165N105 2,139 300,000 SH   SOLE   0 0 300,000
Thermo Fisher Scientific Inc COM 883556102 4,362 25,000 SH   SOLE   0 0 25,000
Threshold Pharmaceuticals COM 885807206 79 201,537 SH   SOLE   0 0 201,537
Ultragenyx Pharmaceutical Inc COM 90400D108 2,209 35,573 SH   SOLE   0 0 35,573
United Health Group Inc COM 91324P102 16,688 90,000 SH   SOLE   0 0 90,000
Universal Health Services Inc B COM 913903100 6,104 50,000 SH   SOLE   0 0 50,000
Walgreens Boots Alliance Inc COM 931427108 7,831 100,000 SH   SOLE   0 0 100,000
Wells Fargo & Co COM 949746101 405 7,305 SH   SOLE   0 0 7,305
Vertex Pharmaceuticals Inc COM 92532F100 12,244 95,013 SH   SOLE   0 0 95,013
Xencor Inc COM 98401F105 5,479 259,556 SH   SOLE   0 0 259,556
Zimmer Biomet Hgs Inc COM 98956P102 11,556 90,000 SH   SOLE   0 0 90,000