The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2U INC COM USD0.001 COM 90214J101 127,331 3,210,563 SH   DFND   780,157 0 2,430,406
ABIOMED INC COM 003654100 1,866 14,901 SH   DFND   3,562 0 11,339
ABRAXAS PETE CORP COM 003830106 838 415,071 SH   DFND   48,644 0 366,427
ACACIA COMMUNICATIONS INC COM COM 00401C108 69,263 1,181,565 SH   DFND   238,248 0 943,317
ACADIA HEALTHCARE COMPANY INC COM COM 00404A109 6,280 144,027 SH   DFND   4,136 0 139,891
ACADIA PHARMACEUTICALS INC COM COM 004225108 308 8,946 SH   DFND   1,700 0 7,246
ACCENTURE PLC CLS A USD0.0000225 COM G1151C101 786 6,553 SH   DFND   1,118 0 5,435
ACTIVISION BLIZZARD INC COM COM 00507V109 89,258 1,790,171 SH   DFND   347,306 0 1,442,865
ADESTO TECHNOLOGIES CORP COM COM 00687D101 6,943 1,673,088 SH   DFND   97,291 0 1,575,797
ADIDAS AG NPV (REGD) ISIN #DE000A1EWWW0 SEDOL #4031976 COM D0066B185 26,735 140,247 SH   DFND   52,095 0 88,152
ADOBE SYS INC COM 00724F101 66,822 513,499 SH   DFND   173,034 0 340,465
ADVANCED DRAINAGE SYSTEM COM USD0.01 COM 00790R104 365 16,672 SH   DFND   494 0 16,178
ADVERUM BIOTECHNOLOGIES INC COM COM 00773U108 123 45,425 SH   DFND   20,510 0 24,915
ALIBABA GROUP HLDG LTD SPONSORED ADS COM 01609W102 36,117 334,945 SH   DFND   130,071 0 204,874
ALIGN TECHNOLOGY INC COM COM 016255101 80,247 699,560 SH   DFND   86,147 0 613,413
ALLEGIANT TRAVEL CO COM COM 01748X102 18,293 114,150 SH   DFND   8,119 0 106,031
ALLERGAN PLC. COM USD0.0001 COM G0177J108 396 1,657 SH   DFND   46 0 1,611
ALMOST FAMILY INC COM 020409108 18,095 372,329 SH   DFND   55,660 0 316,669
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 61,810 1,206,049 SH   DFND   292,798 0 913,251
ALPHABET INC CAP STK CL A COM 02079K305 41,061 48,432 SH   DFND   4,790 0 43,642
ALPHABET INC CAP STK CL C COM 02079K107 86,076 103,761 SH   DFND   19,408 0 84,353
ALTERYX INC COM CL A COM 02156B103 66 4,229 SH   DFND   0 0 4,229
AMAZON.COM INC COM 023135106 472,812 533,323 SH   DFND   198,513 0 334,810
AMBER ROAD INC COM USD0.001 COM 02318Y108 568 73,562 SH   DFND   7,099 0 66,463
AMEDISYS INC COM COM 023436108 42,492 831,707 SH   DFND   405,281 0 426,426
AMERICAN INTL GROUP INC COM NEW COM 026874784 206 3,303 SH   DFND   91 0 3,212
AMERICAN TOWER CORPORATION COM 03027X100 11,007 90,564 SH   DFND   8,593 0 81,971
APACHE CORP COM 037411105 70,745 1,376,630 SH   DFND   153,457 0 1,223,173
APPLE INC COM 037833100 3,826 26,630 SH   DFND   6,177 0 20,453
APPLIED OPTOELECTRONICS INC COM COM 03823U102 15,142 269,673 SH   DFND   28,948 0 240,725
ARISTA NETWORKS INC COM USD0.0001 COM 040413106 92,434 698,830 SH   DFND   36,231 0 662,599
AT HOME GROUP INC COM COM 04650Y100 1,372 90,521 SH   DFND   7,172 0 83,349
ATHENAHEALTH INC DELAWARE COM 04685W103 1,225 10,870 SH   DFND   2,194 0 8,676
ATKORE INTL GROUP INC COM COM 047649108 6,551 249,266 SH   DFND   48,229 0 201,037
ATLASSIAN CORPORATION PLC COM USD0.1 CL A COM G06242104 15,131 505,197 SH   DFND   65,068 0 440,129
AUTO TRADER GROUP PLC ORD GBP0.01 ISIN #GB00BVYVFW23 SEDOL #BVYV COM G06708104 8,819 1,797,807 SH   DFND   239,579 0 1,558,228
AUTODESK INC COM COM 052769106 70,063 810,263 SH   DFND   133,391 0 676,872
AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL # COM 05462W109 640 16,871 SH   DFND   16,275 0 596
AXOGEN INC COM COM 05463X106 5,847 559,516 SH   DFND   120,867 0 438,649
BAIDU INC SPONS ADR REPR 0.10 ORD CLS A COM 056752108 8,944 51,841 SH   DFND   11,641 0 40,200
BANK OF THE OZARKS INC COM COM 063904106 1,778 34,178 SH   DFND   2,683 0 31,495
BASIC ENERGY SVCS INC NEW COM NEW COM 06985P209 7,119 213,403 SH   DFND   13,681 0 199,722
BELLATRIX EXPLORATION LTD COM ISIN #CA0783141017 SEDOL #B580BW5 COM 078314101 509 640,749 SH   DFND   109,351 0 531,398
BERKLEY W R CORP COM 084423102 4,778 67,655 SH   DFND   17,947 0 49,708
BERKSHIRE HATHAWAY INC DEL CL B NEW COM 084670702 33 200 SH   DFND   0 0 200
BIOSCRIP INC COM 09069N108 7,422 4,365,726 SH   DFND   853,321 0 3,512,405
BLACKLINE INC COM COM 09239B109 183 6,154 SH   DFND   3,285 0 2,869
BMC STK HLDGS INC COM COM 05591B109 27,994 1,238,673 SH   DFND   144,780 0 1,093,893
BOINGO WIRELESS INC COM USD0.0001 COM 09739C102 26,363 2,029,475 SH   DFND   316,992 0 1,712,483
BOSTON SCIENTIFIC CORP COM 101137107 1,171 47,076 SH   DFND   20,722 0 26,354
BOX INC CL A COM 10316T104 266 16,315 SH   DFND   2,161 0 14,154
BRIGHTCOVE INC COM USD0.001 COM 10921T101 4,665 524,204 SH   DFND   99,361 0 424,843
C S X CORP COM 126408103 3,058 65,700 SH   DFND   11,931 0 53,769
C&J ENERGY SVCS INC NEW COM COM 12674R100 7,779 228,468 SH   DFND   42,317 0 186,151
CAESARS ENTMT CORP COM COM 127686103 2,754 288,385 SH   DFND   47,710 0 240,675
CANADA GOOSE HOLDINGS INC COM NPV SUB VTNG SHS ISIN #CA135086106 COM 135086106 650 40,755 SH   DFND   481 0 40,274
CARDIOVASCULAR SYS INC DEL COM COM 141619106 1,828 64,664 SH   DFND   13,801 0 50,863
CARROLS RESTAURANT GROUP INC COM COM 14574X104 12,201 862,233 SH   DFND   80,358 0 781,875
CATAPULT GROUP INTL LTD ISIN #AU000000CAT9 SEDOL #BTL0Y76 COM Q2159P101 18,168 10,584,823 SH   DFND   2,499,895 0 8,084,928
CAVIUM INC COM COM 14964U108 45,004 628,020 SH   DFND   37,968 0 590,052
CBS CORP NEW CL B COM 124857202 1,942 27,994 SH   DFND   5,616 0 22,378
CHARTER COMMUNICATIONS INC NEW CL A COM 16119P108 195 596 SH   DFND   26 0 570
CHIPOTLE MEXICAN GRILL INC COM COM 169656105 17 39 SH   DFND   11 0 28
CITIGROUP INC COM NEW COM 172967424 4,011 67,053 SH   DFND   11,376 0 55,677
COGENT COMMUNICATION HLDGS INC COM NEW COM 19239V302 308 7,148 SH   DFND   667 0 6,481
COGNEX CORP COM COM 192422103 25,794 307,255 SH   DFND   85,699 0 221,556
CONSTELLATION BRANDS INC CL A COM 21036P108 8,384 51,729 SH   DFND   4,650 0 47,079
COSTAR GROUP INC COM COM 22160N109 14,566 70,292 SH   DFND   10,207 0 60,085
COSTCO WHOLESALE CORP COM 22160K105 163 972 SH   DFND   26 0 946
CRIMSON WINE GROUP COM USD0.01 COM 22662X100 203 20,297 SH   DFND   525 0 19,772
CTRIP.COM INTERNATIONAL LTD ADS EACH REP 0.125 ORD USD0.01 COM 22943F100 41 835 SH   DFND   145 0 690
DECKERS OUTDOOR CORP COM COM 243537107 505 8,447 SH   DFND   3,994 0 4,453
DEERE & COMPANY COM 244199105 11 100 SH   DFND   0 0 100
DELTA AIR LINES INC DEL COM NEW COM 247361702 7,134 155,225 SH   DFND   4,627 0 150,598
DEXCOM INC COM 252131107 38,379 452,955 SH   DFND   143,864 0 309,091
DIRTT ENVIRONMENTAL SOLUT LTD COM ISIN #CA25490H1064 SEDOL #BH13 COM 25490H106 52,311 9,980,713 SH   DFND   604,663 0 9,376,050
DOMINOS PIZZA ENTERPRISES LIMITED NPV ISIN #AU000000DMP0 SEDOL # COM Q32503106 36,512 823,512 SH   DFND   246,146 0 577,366
DXP ENTERPRISES INC NEW COM 233377407 903 23,848 SH   DFND   21,962 0 1,886
E L F BEAUTY INC COM COM 26856L103 22,503 781,366 SH   DFND   282,096 0 499,270
ECO STIM ENERGY SOLUTIONS INC COM COM 27888D101 992 847,670 SH   DFND   70,475 0 777,195
ECOSYNTHETIX INC COM ISIN #CA27923D1087 SEDOL #B4XBZ35 COM 27923D108 110 62,312 SH   DFND   4,804 0 57,508
ELBIT SYSTEMS LTD ISIN #IL0010811243 SEDOL #6308913 COM M3760D101 31,500 277,165 SH   DFND   120,364 0 156,801
ELECTRONIC ARTS COM 285512109 29,529 329,858 SH   DFND   61,210 0 268,648
ENPHASE ENERGY INC COM USD0.00001 COM 29355A107 1,231 898,485 SH   DFND   41,929 0 856,556
ENZO BIOCHEM INC COM 294100102 6,958 831,354 SH   DFND   215,317 0 616,037
EPAM SYS INC COM USD0.001 COM 29414B104 46,699 618,362 SH   DFND   35,128 0 583,234
ESPERION THERAPEUTICS INC COM USD0.001 COM 29664W105 61 1,740 SH   DFND   204 0 1,536
ETSY INC COM COM 29786A106 175 16,442 SH   DFND   4,210 0 12,232
EVERBRIDGE INC COM COM 29978A104 12,912 628,926 SH   DFND   100,023 0 528,903
EVOLENT HEALTH INC CL A COM 30050B101 5,833 261,566 SH   DFND   51,738 0 209,828
EXACT SCIENCES CORP COM 30063P105 75,296 3,187,795 SH   DFND   632,528 0 2,555,267
EXTRACTION OIL AND GAS INC COM COM 30227M105 11,101 598,425 SH   DFND   79,644 0 518,781
FACEBOOK INC COM USD0.000006 CL A COM 30303M102 300,523 2,115,617 SH   DFND   580,171 0 1,535,446
FAIRFAX INDIA HOLDINGS CORPORATION COM SUB VTG SHS ISIN #CA30389 COM 303897102 532 40,285 SH   DFND   31,340 0 8,945
FARMER BROS CO COM COM 307675108 3,271 92,540 SH   DFND   21,645 0 70,895
FB FINL CORP COM COM 30257X104 349 9,877 SH   DFND   4,239 0 5,638
FEVERTREE DRINKS PLC ORD GBP0.0025 ISIN #GB00BRJ9BJ26 SEDOL #BRJ COM G33929103 1,023 54,380 SH   DFND   29,742 0 24,638
FIRST REP BK SAN FRANCISCO CAL COM COM 33616C100 33,212 354,036 SH   DFND   49,122 0 304,914
FLEXION THERAPEUTICS INC COM COM 33938J106 115,294 4,284,412 SH   DFND   784,340 0 3,500,072
FLIR SYS INC COM 302445101 23,825 656,698 SH   DFND   257,438 0 399,260
FORTUNE BRANDS HOME & SECURITY INC USD0.01 COM 34964C106 72 1,180 SH   DFND   23 0 1,157
FOUNDATION MEDICINE INC USD0.0001 COM 350465100 51,950 1,610,865 SH   DFND   496,053 0 1,114,812
FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31 COM 351858105 5,958 90,954 SH   DFND   2,715 0 88,239
FULGENT GENETICS INC COM COM 359664109 42 3,851 SH   DFND   0 0 3,851
GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5 COM B44170106 27,830 318,950 SH   DFND   101,795 0 217,155
GEOPARK LIMITED COM USD0.001 COM G38327105 1,907 265,573 SH   DFND   6,403 0 259,170
GIGAMON INC COM USD0.0001 COM 37518B102 33,777 950,113 SH   DFND   85,415 0 864,698
GILDAN ACTIVEWEAR INC COM ISIN #CA3759161035 SEDOL #2254645 COM 375916103 9,560 353,541 SH   DFND   38,295 0 315,246
GILEAD SCIENCES INC COM 375558103 288 4,240 SH   DFND   817 0 3,423
GLAUKOS CORP COM COM 377322102 76,761 1,496,311 SH   DFND   336,826 0 1,159,485
GLOBAL BLOOD THERAPEUTICS INC COM COM 37890U108 345 9,350 SH   DFND   3,527 0 5,823
GLOBANT SA USD1.20 COM L44385109 824 22,650 SH   DFND   14,769 0 7,881
GODADDY INC CL A COM 380237107 5,562 146,751 SH   DFND   24,157 0 122,594
GOLAR LNG LIMITED COM STK USD1.00 COM G9456A100 9,112 326,246 SH   DFND   26,955 0 299,291
GOLD STD VENTURES CORP COM ISIN #CA3807381049 SEDOL #B05J9S2 COM 380738104 2,271 1,051,478 SH   DFND   104,900 0 946,578
GOLDEN MINERALS CO COM ISIN #US3811191069 SEDOL #B3K4M51 COM 381119106 31 49,704 SH   DFND   5,744 0 43,960
GRACE W R & CO DEL NEW COM 38388F108 16,622 238,447 SH   DFND   39,293 0 199,154
GREEN BRICK PARTNERS INC COM 392709101 3,219 323,532 SH   DFND   4,082 0 319,450
GRUPO FINANCIERO GALICIA SA ADR EACH REPR 10 CLASS B ARS1 LVL11 COM 399909100 107 2,819 SH   DFND   540 0 2,279
GTT COMMUNICATIONS INC COM USD0.0001 COM 362393100 46,920 1,926,918 SH   DFND   350,925 0 1,575,993
GUIDEWIRE SOFTWARE INC COM USD0.0001 COM 40171V100 2,033 36,099 SH   DFND   8,071 0 28,028
H &E EQUIPMENT SERVICES INC COM COM 404030108 2,258 92,092 SH   DFND   13,483 0 78,609
HDFC BANK LTD ADS EACH REPR 3 INR10(MGT) COM 40415F101 43,133 573,429 SH   DFND   167,801 0 405,628
HEALTHEQUITY INC COM COM 42226A107 3,642 85,789 SH   DFND   6,628 0 79,161
HERC HLDGS INC COM COM 42704L104 414 8,460 SH   DFND   5,010 0 3,450
HUBSPOT INC COM COM 443573100 87,752 1,449,245 SH   DFND   238,130 0 1,211,115
ICICI BANK LIMITED ADR EACH REPR 2 ORD INR10(SPON) COM 45104G104 120 13,956 SH   DFND   9,047 0 4,909
ILLUMINA INC COM COM 452327109 455 2,666 SH   DFND   530 0 2,136
IMPINJ INC COM COM 453204109 59,380 1,961,678 SH   DFND   259,794 0 1,701,884
INCYTE CORP COM COM 45337C102 73,509 549,928 SH   DFND   229,098 0 320,830
INFINERA CORPORATION COM COM 45667G103 86 8,395 SH   DFND   1,024 0 7,371
INPHI CORPORATION COM USD0.001 COM 45772F107 8,145 166,845 SH   DFND   29,198 0 137,647
INSULET CORP COM COM 45784P101 644 14,937 SH   DFND   6,046 0 8,891
INTUITIVE SURGICAL INC COM NEW COM 46120E602 55,860 72,880 SH   DFND   5,109 0 67,771
IRHYTHM TECHNOLOGIES INC COM COM 450056106 3,659 97,305 SH   DFND   11,493 0 85,812
ITAU UNIBANCO HOLDINGS S.A. ADR EACH REPR 1 PRF NPV COM 465562106 3,756 311,195 SH   DFND   51,871 0 259,324
J JILL INC COM COM 46620W102 845 59,909 SH   DFND   3,498 0 56,411
JD COM INC SPONSORED ADR REPSTG COM CL A COM 47215P106 352 11,329 SH   DFND   2,958 0 8,371
JELD-WEN HLDG INC COM COM 47580P103 2,330 70,943 SH   DFND   4,220 0 66,723
KANSAS CITY SOUTHERN COM COM 485170302 6,827 79,603 SH   DFND   7,720 0 71,883
KB HOME COM COM 48666K109 14,605 734,681 SH   DFND   83,212 0 651,469
KITE PHARMA INC COM COM 49803L109 810 10,316 SH   DFND   3,724 0 6,592
KORNIT DIGITAL LTD ORD ILS0.01 COM M6372Q113 31,859 1,668,032 SH   DFND   425,396 0 1,242,636
KRAFT HEINZ CO COM COM 500754106 90 993 SH   DFND   27 0 966
LGI HOMES INC COM COM 50187T106 70,730 2,085,828 SH   DFND   379,651 0 1,706,177
LHC GROUP INC COM COM 50187A107 1,565 29,043 SH   DFND   8,625 0 20,418
LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP COM 531229706 4,877 203,713 SH   DFND   5,605 0 198,108
LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP COM 531229888 6,399 270,560 SH   DFND   7,181 0 263,379
LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA COM 531229854 110 3,231 SH   DFND   87 0 3,144
LIVEPERSON INC COM 538146101 8,043 1,174,111 SH   DFND   34,927 0 1,139,184
LUMBER LIQUIDATORS HLDGS INC COM COM 55003T107 38,643 1,841,021 SH   DFND   659,980 0 1,181,041
LUMENTUM HLDGS INC COM COM 55024U109 90,809 1,702,138 SH   DFND   325,935 0 1,376,203
MADISON SQUARE GARDEN CO NEW CL A COM 55825T103 3,444 17,246 SH   DFND   3,030 0 14,216
MAKEMYTRIP LTD USD0.0005 COM V5633W109 4,213 121,757 SH   DFND   25,269 0 96,488
MARTIN MARIETTA MATLS INC COM 573284106 63,567 291,260 SH   DFND   32,760 0 258,500
MASONITE INTERNATIONAL CORP COM NPV COM 575385109 17,146 216,352 SH   DFND   37,474 0 178,878
MASTERCARD INCORPORATED CL A COM 57636Q104 12,475 110,916 SH   DFND   21,147 0 89,769
MCDONALDS CORP COM 580135101 47,943 369,901 SH   DFND   25,808 0 344,093
MEG ENERGY CORP COM ISIN #CA5527041084 SEDOL #B4XF9J1 COM 552704108 72 14,200 SH   DFND   3,600 0 10,600
MERCADOLIBRE INC COM 58733R102 4,783 22,617 SH   DFND   2,751 0 19,866
MERCURY SYS INC COM COM 589378108 35,579 911,118 SH   DFND   267,005 0 644,113
METRO BANK PLC ORD GBP0.000001 ISIN #GB00BZ6STL67 SEDOL #BZ6STL6 COM G60640102 125,472 3,083,631 SH   DFND   607,895 0 2,475,736
MICRON TECHNOLOGY COM 595112103 793 27,433 SH   DFND   11,112 0 16,321
MICROSOFT CORP COM 594918104 10,212 155,059 SH   DFND   32,008 0 123,051
MOBILEYE NV EUR0.01 COM N51488117 5,797 94,420 SH   DFND   8,496 0 85,924
MOLSON COORS BREWING CO CL B COM 60871R209 241 2,513 SH   DFND   64 0 2,449
MONOLITHIC PWR SYS INC COM COM 609839105 10,025 108,847 SH   DFND   10,624 0 98,223
MORRISON(WM.)SUPERMA KETS ORD GBP0.10 ISIN #GB0006043169 SEDOL # COM G62748119 299 99,739 SH   DFND   23,334 0 76,405
MULESOFT INC CL A COM 625207105 30,691 1,261,452 SH   DFND   367,788 0 893,664
NETFLIX COM INC COM COM 64110L106 391,156 2,646,345 SH   DFND   611,431 0 2,034,914
NEVRO CORP COM USD0.001 COM 64157F103 14,931 159,354 SH   DFND   4,769 0 154,585
NEW HOME CO INC COM COM 645370107 332 31,707 SH   DFND   2,500 0 29,207
NEW RELIC INC COM COM 64829B100 5,349 144,282 SH   DFND   24,732 0 119,550
NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV COM 654445303 23,070 796,035 SH   DFND   75,582 0 720,453
NINTENDO CO LTD NPV ISIN #JP3756600007 SEDOL #6639550 COM J51699106 672 2,897 SH   DFND   648 0 2,249
NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST COM 65506L105 69 1,331 SH   DFND   0 0 1,331
NORTHERN DYNASTY MINS COM NPV ISIN #CA66510M2040 SEDOL #2637848 COM 66510M204 1,464 1,024,013 SH   DFND   52,042 0 971,971
NOVELION THERAPEUTICS INC COM NPV(POST REV SPLT) ISIN #CA67001K2 COM 67001K202 3,561 331,599 SH   DFND   66,226 0 265,373
NUTANIX INC CL A COM 67059N108 781 41,598 SH   DFND   9,412 0 32,186
NUTRI SYS INC NEW COM COM 67069D108 11,076 199,564 SH   DFND   34,019 0 165,545
NUVASIVE INC COM COM 670704105 2,155 28,863 SH   DFND   5,436 0 23,427
NUVECTRA CORP COM COM 67075N108 5,791 847,851 SH   DFND   139,814 0 708,037
NV5 GLOBAL INC COM COM 62945V109 6,766 179,943 SH   DFND   8,060 0 171,883
NVIDIA CORP COM 67066G104 7,329 67,284 SH   DFND   29,866 0 37,418
NXSTAGE MED INC COM COM 67072V103 132,960 4,955,630 SH   DFND   893,621 0 4,062,009
OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74 COM G6718L106 56,728 18,824,246 SH   DFND   3,508,358 0 15,315,888
OCEANAGOLD CORPORATION COM ISIN #CA6752221037 SEDOL #B1Z7L21 COM 675222103 2,790 944,550 SH   DFND   27,045 0 917,505
OCLARO INC COM NEW COM 67555N206 7,029 715,779 SH   DFND   130,366 0 585,413
OOMA INC COM COM 683416101 3,510 352,798 SH   DFND   55,084 0 297,714
ORBITAL ATK INC COM COM 68557N103 102 1,037 SH   DFND   204 0 833
PACIFIC BIOSCIENCES CALIFORNIA INC COM USD0.0001 COM 69404D108 18,710 3,618,977 SH   DFND   911,603 0 2,707,374
PACIFIC ETHANOL INC COM PAR $.001 COM 69423U305 15 2,218 SH   DFND   646 0 1,572
PACIRA PHARMACEUTICALS INC COM USD0.001 COM 695127100 55,852 1,224,814 SH   DFND   448,776 0 776,038
PANDORA MEDIA INC COM COM 698354107 160 13,525 SH   DFND   1,219 0 12,306
PDF SOLUTIONS INC COM 693282105 36,824 1,627,953 SH   DFND   166,169 0 1,461,784
PENSKE AUTOMOTIVE GROUP INC COM 70959W103 3,757 80,269 SH   DFND   18,724 0 61,545
POOL CORP COM COM 73278L105 52,176 437,245 SH   DFND   65,235 0 372,010
PROOFPOINT INC COM USD0.0001 COM 743424103 6,883 92,564 SH   DFND   6,048 0 86,516
PTC INC COM COM 69370C100 132 2,519 SH   DFND   1,560 0 959
PURE STORAGE INC CL A COM 74624M102 1,922 195,524 SH   DFND   20,043 0 175,481
PURPLEBRICKS GROUP PLC ORD GBP0.01 ISIN #GB00BYV2MV74 SEDOL #BYV COM G7S98A108 24,850 6,997,531 SH   DFND   2,234,657 0 4,762,874
Q2 HLDGS INC COM COM 74736L109 45,602 1,308,518 SH   DFND   236,401 0 1,072,117
RENAISSANCERE HOLDINGS LTD COM STK USD1 COM G7496G103 24 167 SH   DFND   0 0 167
REPUBLIC FIRST BANCORP INC COM COM 760416107 1,540 185,552 SH   DFND   4,553 0 180,999
RIGHTMOVE PLC WINTERHILL SHS ISIN #GB00B2987V85 SEDOL #B2987V8 COM G75657109 18,859 378,185 SH   DFND   51,660 0 326,525
RINGCENTRAL INC-CLASS A COM 76680R206 97,311 3,438,541 SH   DFND   565,347 0 2,873,194
SAFETY INS GROUP INC COM 78648T100 442 6,312 SH   DFND   1,170 0 5,142
SALESFORCE COM INC COM 79466L302 20,781 251,919 SH   DFND   49,872 0 202,047
SANGAMO THERAPEUTICS INC COM COM 800677106 154 29,576 SH   DFND   0 0 29,576
SAREPTA THERAPEUTICS INC COM COM 803607100 434 14,659 SH   DFND   5,806 0 8,853
SCIENTIFIC GAMES CRP CL A COM 80874P109 1,564 66,148 SH   DFND   15,345 0 50,803
SCOUT24 AG NPV 144A ISIN #DE000A12DM80 SEDOL #BYT9340 COM D345XT105 72 2,187 SH   DFND   422 0 1,765
SECTOR SPDR TR SHS BEN INT TECHNOLOGY COM 81369Y803 1,690 31,695 SH   DFND   6,296 0 25,399
SENESTECH INC COM COM 81720R109 8,304 1,049,790 SH   DFND   112,054 0 937,736
SEQUANS COMMUNICATIONS SPON ADR EA REPR 1 ORD SHS COM 817323108 191 69,277 SH   DFND   5,920 0 63,357
SERVICENOW INC COM USD0.001 COM 81762P102 12,525 143,193 SH   DFND   24,662 0 118,531
SHAKE SHACK INC CL A COM 819047101 73,173 2,190,807 SH   DFND   501,301 0 1,689,506
SHERWIN WILLIAMS CO COM 824348106 819 2,640 SH   DFND   75 0 2,565
SHOPIFY INC NPV SUBORDINATED A ISIN #CA82509L1076 SEDOL #BX865C7 COM 82509L107 17,674 259,564 SH   DFND   46,871 0 212,693
SIENTRA INC COM USD0.01 COM 82621J105 6,884 817,609 SH   DFND   113,671 0 703,938
SIGNATURE BK NEW YORK N Y COM COM 82669G104 3,825 25,774 SH   DFND   4,692 0 21,082
SILVER WHEATON CORPORATION COM NPV ISIN #CA8283361076 SEDOL #B05 COM 828336107 1,935 92,867 SH   DFND   635 0 92,232
SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2 COM 828363101 1,101 712,761 SH   DFND   105,682 0 607,079
SIRIUS XM HLDGS INC COM COM 82968B103 155 30,140 SH   DFND   5,808 0 24,332
SITEONE LANDSCAPE SUPPLY INC COM COM 82982L103 15,779 325,951 SH   DFND   36,089 0 289,862
SIX FLAGS ENTMT CORP NEW COM COM 83001A102 9,439 158,661 SH   DFND   51,370 0 107,291
SMART SAND INC COM COM 83191H107 6,227 383,190 SH   DFND   70,381 0 312,809
SNAP INC CL A COM 83304A106 48,425 2,149,349 SH   DFND   430,664 0 1,718,685
SPARK THERAPEUTICS INC COM COM 84652J103 367 6,887 SH   DFND   3,206 0 3,681
SPIRIT AIRLS INC COM COM 848577102 31,667 596,711 SH   DFND   63,252 0 533,459
SPLUNK INC COM USD0.001 COM 848637104 8,640 138,708 SH   DFND   22,067 0 116,641
SQUARE INC CL A COM 852234103 7,513 434,779 SH   DFND   54,899 0 379,880
SS&C TECHNOLOGIES HLDGS INC COM COM 78467J100 26,050 735,887 SH   DFND   119,833 0 616,054
STARBUCKS CORP COM USD0.001 COM 855244109 1,850 31,681 SH   DFND   4,752 0 26,929
STRAIGHT PATH COMMUNICATIONS INC COM USD0.01 CL B COM 862578101 26,784 744,617 SH   DFND   120,107 0 624,510
SUMMIT MATLS INC CL A COM 86614U100 8,478 343,092 SH   DFND   6,334 0 336,758
SUNRUN INC COM COM 86771W105 329 60,884 SH   DFND   6,332 0 54,552
SVB FINL GROUP COM 78486Q101 3,874 20,816 SH   DFND   3,749 0 17,067
T MOBILE US INC COM COM 872590104 322 4,992 SH   DFND   474 0 4,518
TAKE-TWO INTERACTIVE SOFTWARE COM COM 874054109 680 11,468 SH   DFND   6,272 0 5,196
TAL EDUCATION GROUP ADS EA REPR 2 CL A ORD SHS COM 874080104 81 756 SH   DFND   479 0 277
TALEND SA ADR EACH REP 1 ORD SHS COM 874224207 1,240 41,648 SH   DFND   7,387 0 34,261
TELADOC INC COM COM 87918A105 28 1,126 SH   DFND   193 0 933
TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM COM G87572163 50,351 1,756,297 SH   DFND   506,139 0 1,250,158
TESLA INC COM COM 88160R101 192,038 690,038 SH   DFND   242,193 0 447,845
THERAPEUTICSMD INC COM COM 88338N107 22,030 3,059,690 SH   DFND   1,083,355 0 1,976,335
TIME INC NEW COM COM 887228104 37 1,927 SH   DFND   0 0 1,927
TRACTOR SUPPLY CO COM 892356106 1,933 28,033 SH   DFND   6,049 0 21,984
TRANSDIGM GROUP INC COM COM 893641100 6,517 29,603 SH   DFND   786 0 28,817
TRIPADVISOR INC COM COM 896945201 135 3,133 SH   DFND   97 0 3,036
TSO3 INC COM ISIN #CA8730151013 SEDOL #2798518 COM 873015101 12,766 5,370,685 SH   DFND   478,396 0 4,892,289
TWILIO INC CL A COM 90138F102 2,430 84,158 SH   DFND   13,731 0 70,427
TWITTER INC COM USD0.000005 COM 90184L102 62 4,136 SH   DFND   4,136 0 0
ULTA BEAUTY INC COM COM 90384S303 82,486 289,190 SH   DFND   40,033 0 249,157
ULTIMATE SOFTWARE GROUP INC COM 90385D107 3,477 17,810 SH   DFND   2,693 0 15,117
UNDER ARMOUR INC COM STK USD0.000333 CLASS A COM 904311107 31 1,556 SH   DFND   1,500 0 56
UNIVERSAL DISPLAY CORP COM 91347P105 312 3,618 SH   DFND   2,734 0 884
VALIDUS HOLDING LTD COM STK USD0.175 COM G9319H102 6,064 107,531 SH   DFND   27,428 0 80,103
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VEEVA SYS INC CL A COM COM 922475108 46,482 906,439 SH   DFND   294,292 0 612,147
VIVENDI SA EUR5.50 ISIN #FR0000127771 SEDOL #4834777 COM F97982106 21,386 1,097,119 SH   DFND   75,418 0 1,021,701
VOCERA COMMUNICATIONS INC COM COM 92857F107 5,901 237,658 SH   DFND   43,998 0 193,660
VULCAN MATERIALS CO COM 929160109 105 869 SH   DFND   28 0 841
WAGEWORKS INC COM USD0.001 COM 930427109 47 656 SH   DFND   126 0 530
WEIBO CORP SPONSORED ADR COM 948596101 3,690 70,725 SH   DFND   10,511 0 60,214
WELLS FARGO &COMPANY COM USD1.666 COM 949746101 1,568 28,178 SH   DFND   2,770 0 25,408
WORKDAY INC CL A COM 98138H101 8,926 107,180 SH   DFND   20,085 0 87,095
XILINX INC COM 983919101 41,277 713,023 SH   DFND   51,460 0 661,563
XTREME DRILLING CORP ISIN #CA98419V1004 SEDOL #B7J8QB6 COM 98419V100 2,362 1,471,901 SH   DFND   158,429 0 1,313,472
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ZAYO GROUP HLDGS INC COM COM 98919V105 241 7,312 SH   DFND   617 0 6,695
ZENDESK INC COM USD0.01 COM 98936J101 6,465 230,572 SH   DFND   38,675 0 191,897
ZILLOW GROUP INC CL A COM 98954M101 22,497 665,409 SH   DFND   49,540 0 615,869
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