The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abbott Laboratories COM 002824100 5,107 115,000 SH   SOLE   0 0 115,000
AbbVie Inc COM 00287Y109 8,471 130,000 SH   SOLE   0 0 130,000
Abiomed Inc COM 003654100 14,654 117,048 SH   SOLE   0 0 117,048
Acadia Pharmaceuticals Inc COM 004225108 3,094 90,000 SH   SOLE   0 0 90,000
Achillion Pharmaceuticals Inc COM 00448Q201 699 166,000 SH   SOLE   0 0 166,000
Adamas Pharmaceuticals Inc COM 00548A106 2,713 155,000 SH   SOLE   0 0 155,000
Adverum Biotechnologies Inc COM 00773U108 416 154,006 SH   SOLE   0 0 154,006
Aerie Pharmaceuticals Inc COM 00771V108 3,855 85,000 SH   SOLE   0 0 85,000
Aetna Inc COM 00817Y108 6,633 52,000 SH   SOLE   0 0 52,000
Alexion Pharmaceuticals Inc COM 015351109 13,543 111,702 SH   SOLE   0 0 111,702
Alkermes Plc SHS G01767105 8,214 140,409 SH   SOLE   0 0 140,409
Allergan Plc SHS G0177J108 14,096 59,000 SH   SOLE   0 0 59,000
Alnylam Pharmaceuticals Inc COM 02043Q107 6,663 130,000 SH   SOLE   0 0 130,000
AmerisourceBergen Corp COM 03073E105 5,576 63,000 SH   SOLE   0 0 63,000
Amgen Inc COM 031162100 16,407 100,000 SH   SOLE   0 0 100,000
Anheuser-Busch InBev SA ADR spons repr 1 Share COM 03524A108 308 2,806 SH   SOLE   0 0 2,806
Anthem Inc COM 036752103 6,196 37,468 SH   SOLE   0 0 37,468
Anthera Pharmaceuticals Inc COM 03674U201 85 200,000 SH   SOLE   0 0 200,000
Array BioPharma Inc COM 04269X105 3,129 350,000 SH   SOLE   0 0 350,000
Becton Dickinson & Co COM 075887109 917 5,000 SH   SOLE   0 0 5,000
Biogen Inc COM 09062X103 18,593 68,000 SH   SOLE   0 0 68,000
BioMarin Pharmaceutical Inc COM 09061G101 10,973 125,000 SH   SOLE   0 0 125,000
Bioverativ Inc Reg S COM 09075E100 1,688 31,000 SH   SOLE   0 0 31,000
Bristol Myers Squibb Co COM 110122108 10,930 201,000 SH   SOLE   0 0 201,000
Cardinal Health Inc COM 14149Y108 6,116 75,000 SH   SOLE   0 0 75,000
Catabasis Pharmaceuticals Inc COM 14875P107 497 310,756 SH   SOLE   0 0 310,756
Celgene Corp COM 151020104 11,572 93,000 SH   SOLE   0 0 93,000
Centene Corp COM 15135B101 6,242 87,593 SH   SOLE   0 0 87,593
Chimerix Inc COM 16934W106 2,552 400,000 SH   SOLE   0 0 400,000
Cigna Corp COM 125509109 9,375 64,000 SH   SOLE   0 0 64,000
Coherus BioSciences Inc COM 19249H103 2,355 111,357 SH   SOLE   0 0 111,357
Concert Pharm Inc COM 206022105 513 30,099 SH   SOLE   0 0 30,099
CVS Health Corp COM 126650100 10,205 130,000 SH   SOLE   0 0 130,000
DaVita Inc COM 23918K108 3,738 55,000 SH   SOLE   0 0 55,000
Dexcom Inc COM 252131107 4,821 56,900 SH   SOLE   0 0 56,900
Dynavax Technologies Corp COM 268158201 5,859 984,696 SH   SOLE   0 0 984,696
Edwards Lifesciences Corp COM 28176E108 5,644 60,000 SH   SOLE   0 0 60,000
Eli Lilly & Co COM 532457108 14,299 170,000 SH   SOLE   0 0 170,000
Endo International Plc SHS G30401106 4,490 402,303 SH   SOLE   0 0 402,303
Endologix Inc COM 29266S106 11,584 1,600,000 SH   SOLE   0 0 1,600,000
Esperion Therapeutics Inc COM 29664W105 19,186 543,347 SH   SOLE   0 0 543,347
Exelixis Inc COM 30161Q104 13,652 630,000 SH   SOLE   0 0 630,000
Express Scripts Hg Co COM 30219G108 6,327 96,000 SH   SOLE   0 0 96,000
Exxon Mobil Corp COM 30231G102 396 4,823 SH   SOLE   0 0 4,823
FibroGen Inc COM 31572Q808 3,805 154,341 SH   SOLE   0 0 154,341
Ford Motor Co COM 345370860 262 22,511 SH   SOLE   0 0 22,511
Gilead Sciences Inc COM 375558103 14,054 206,916 SH   SOLE   0 0 206,916
Glaukos Corp COM 377322102 16,714 325,800 SH   SOLE   0 0 325,800
Halliburton Co (Hg Co) COM 406216101 380 7,718 SH   SOLE   0 0 7,718
Halozyme Therapeutics Inc COM 40637H109 2,203 170,000 SH   SOLE   0 0 170,000
HCA Holdings Inc COM 40412C101 9,318 104,707 SH   SOLE   0 0 104,707
Hologic Inc COM 436440101 6,383 150,000 SH   SOLE   0 0 150,000
Horizon Pharma Plc SHS G4617B105 25,885 1,751,322 SH   SOLE   0 0 1,751,322
Humana Inc COM 444859102 6,596 32,000 SH   SOLE   0 0 32,000
IBM Corp COM 459200101 308 1,766 SH   SOLE   0 0 1,766
Immunomedics Inc COM 452907108 3,103 479,610 SH   SOLE   0 0 479,610
Incyte Corp Ltd COM 45337C102 15,372 115,000 SH   SOLE   0 0 115,000
Insulet Corp COM 45784P101 1,508 35,000 SH   SOLE   0 0 35,000
Intercept Pharmaceuticals Inc COM 45845P108 3,393 30,000 SH   SOLE   0 0 30,000
Intra-Cellular Therapies Inc COM 46116X101 11,630 715,664 SH   SOLE   0 0 715,664
Intuitive Surgical Inc COM 46120E602 3,066 4,000 SH   SOLE   0 0 4,000
Jazz Pharmaceuticals Plc SHS G50871105 8,754 60,320 SH   SOLE   0 0 60,320
JPMorgan Chase & Co COM 46625H100 425 4,837 SH   SOLE   0 0 4,837
Keryx Biopharmaceuticals Inc COM 492515101 2,619 425,111 SH   SOLE   0 0 425,111
Kite Pharma Inc COM 49803L109 8,634 110,000 SH   SOLE   0 0 110,000
Laboratory Corp of America Hgs COM 50540R409 3,092 21,550 SH   SOLE   0 0 21,550
Lion Biotechnologies Inc COM 53619R102 4,843 650,000 SH   SOLE   0 0 650,000
Macrogenics Inc COM 556099109 3,255 175,000 SH   SOLE   0 0 175,000
Medtronic Plc SHS G5960L103 14,591 181,115 SH   SOLE   0 0 181,115
Merck & Co Inc COM 58933Y105 10,166 160,000 SH   SOLE   0 0 160,000
Microsoft Corp COM 594918104 316 4,793 SH   SOLE   0 0 4,793
Mirati Therapeutics Inc COM 60468T105 260 50,000 SH   SOLE   0 0 50,000
Mylan N.V. COM N59465109 3,509 90,000 SH   SOLE   0 0 90,000
Nektar Therapeutics COM 640268108 11,031 470,000 SH   SOLE   0 0 470,000
Neurocrine Biosciences Inc COM 64125C109 3,681 85,000 SH   SOLE   0 0 85,000
Nevro Corp COM 64157F103 10,552 112,614 SH   SOLE   0 0 112,614
NxStage Medical Inc COM 67072V103 4,129 153,901 SH   SOLE   0 0 153,901
Ocular Therapeutix Inc COM 67576A100 371 40,000 SH   SOLE   0 0 40,000
Omnicell Inc COM 68213N109 4,006 98,537 SH   SOLE   0 0 98,537
Ophthotech Corp COM 683745103 88 23,920 SH   SOLE   0 0 23,920
Orexigen Therapeutics Inc COM 686164302 413 120,000 SH   SOLE   0 0 120,000
Pfizer Inc COM 717081103 11,475 335,422 SH   SOLE   0 0 335,422
Portola Pharmaceuticals Inc COM 737010108 4,734 120,805 SH   SOLE   0 0 120,805
Qualcomm Inc COM 747525103 308 5,368 SH   SOLE   0 0 5,368
Radius Health Inc COM 750469207 2,899 75,000 SH   SOLE   0 0 75,000
Regeneron Pharmaceuticals Inc COM 75886F107 14,338 37,000 SH   SOLE   0 0 37,000
Regulus Therapeutic Inc COM 75915K101 979 593,629 SH   SOLE   0 0 593,629
Revance Therapeutics Inc COM 761330109 4,368 210,000 SH   SOLE   0 0 210,000
Rigel Pharmaceuticals Inc COM 766559603 4,243 1,282,000 SH   SOLE   0 0 1,282,000
Sage Therapeutics Inc COM 78667J108 5,164 72,659 SH   SOLE   0 0 72,659
Staar Surgical Co COM 852312305 281 28,711 SH   SOLE   0 0 28,711
Supernus Pharmaceuticals Inc COM 868459108 7,199 230,000 SH   SOLE   0 0 230,000
Tandem Diabetes Care Inc COM 875372104 281 234,000 SH   SOLE   0 0 234,000
Tesaro Inc COM 881569107 769 5,000 SH   SOLE   0 0 5,000
Tetraphase Pharmaceuticals Inc COM 88165N105 2,757 300,000 SH   SOLE   0 0 300,000
Thermo Fisher Scientific Inc COM 883556102 6,144 40,000 SH   SOLE   0 0 40,000
Threshold Pharmaceuticals COM 885807206 115 201,537 SH   SOLE   0 0 201,537
United Health Group Inc COM 91324P102 10,661 65,000 SH   SOLE   0 0 65,000
Universal Health Services Inc B COM 913903100 4,356 35,000 SH   SOLE   0 0 3,500
Walgreens Boots Alliance Inc COM 931427108 3,737 45,000 SH   SOLE   0 0 45,000
Wells Fargo & Co COM 949746101 407 7,305 SH   SOLE   0 0 7,305
Vertex Pharmaceuticals Inc COM 92532F100 10,390 95,013 SH   SOLE   0 0 95,013
Xencor Inc COM 98401F105 6,219 260,000 SH   SOLE   0 0 260,000
Zimmer Biomet Hgs Inc COM 98956P102 8,548 70,000 SH   SOLE   0 0 70,000