The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ADIENT PLC ORD SHS G0084W101 16,961 289,435 SH   DFND 1,2,3,4 0 289,435 0
ALCOBRA LTD SHS M2239P109 1,365 650,000 SH   DFND 1,2,3,4 0 650,000 0
ALEXION PHARMACEUTICALS INC COM 015351109 5,506 45,000 SH   DFND 1,2,3,4 0 45,000 0
ALLERGAN PLC PFD CONV SER A G0177J116 2,287 3,000 SH   DFND 1,2,3,4 0 3,000 0
ALTRIA GROUP INC COM 02209S103 17,749 262,483 SH   DFND 1,2,3,4 0 262,483 0
AMAG PHARMACEUTICALS INC COM 00163U106 5,062 145,474 SH   DFND 1,2,3,4 0 145,474 0
AMAZON COM INC COM 023135106 16,337 21,786 SH   DFND 1,2,3,4 0 21,786 0
AMERICAN AIRLS GROUP INC COM 02376R102 17,627 815,000 SH   DFND 1,2,3,4 0 815,000 0
ANTARES PHARMA INC COM 036642106 4,699 2,016,830 SH   DFND 1,2,3,4 0 2,016,830 0
APACHE CORP COM 037411105 50,182 790,644 SH   DFND 1,2,3,4 0 790,644 0
ARCHER DANIELS MIDLAND CO COM 039483102 2,283 50,000 SH   DFND 1,2,3,4 0 50,000 0
ARCHER DANIELS MIDLAND CO COM 039483102 18,260 400,000 SH Call DFND 1,2,3,4 0 400,000 0
ARCONIC INC COM 03965L100 4,375 236,000 SH   DFND 1,2,3,4 0 236,000 0
ARIAD PHARMACEUTICALS INC COM 04033A100 995 80,000 SH Put DFND 1,2,3,4 0 80,000 0
ASTRAZENECA PLC SPONSORED ADR 046353108 8,242 301,700 SH Call DFND 1,2,3,4 0 301,700 0
ATHENE HLDG LTD CL A G0684D107 8,537 192,308 SH   DFND 1,2,3,4 0 192,308 0
BLOOMIN BRANDS INC COM 094235108 3,155 175,000 SH   DFND 1,2,3,4 0 175,000 0
BRINKER INTL INC COM 109641100 2,972 60,000 SH   DFND 1,2,3,4 0 60,000 0
CALLON PETE CO DEL COM 13123X102 25,358 1,649,869 SH   DFND 1,2,3,4 0 1,649,869 0
CATALYST PHARMACEUTICALS INC COM 14888U101 794 756,311 SH   DFND 1,2,3,4 0 756,311 0
CHURCH & DWIGHT INC COM 171340102 8,396 190,000 SH   DFND 1,2,3,4 0 190,000 0
CITIGROUP INC COM NEW 172967424 29,715 500,000 SH Put DFND 1,2,3,4 0 500,000 0
CLOROX CO DEL COM 189054109 12,002 100,000 SH Call DFND 1,2,3,4 0 100,000 0
COLGATE PALMOLIVE CO COM 194162103 19,632 300,000 SH Call DFND 1,2,3,4 0 300,000 0
COLUCID PHARMACEUTICALS INC COM 19716T101 2,201 60,461 SH   DFND 1,2,3,4 0 60,461 0
CSRA INC COM 12650T104 6,368 200,000 SH   DFND 1,2,3,4 0 200,000 0
CSX CORP COM 126408103 15,342 426,989 SH   DFND 1,2,3,4 0 426,989 0
CYMABAY THERAPEUTICS INC COM 23257D103 1,629 941,348 SH   DFND 1,2,3,4 0 941,348 0
DANA INCORPORATED COM 235825205 4,955 261,040 SH   DFND 1,2,3,4 0 261,040 0
DAVE & BUSTERS ENTMT INC COM 238337109 7,087 125,884 SH   DFND 1,2,3,4 0 125,884 0
DELL TECHNOLOGIES INC COM CL V 24703L103 31,243 568,368 SH   DFND 1,2,3,4 0 568,368 0
DELTA AIR LINES INC DEL COM NEW 247361702 6,149 125,000 SH   DFND 1,2,3,4 0 125,000 0
DEVON ENERGY CORP NEW COM 25179M103 20,575 450,506 SH   DFND 1,2,3,4 0 450,506 0
DOW CHEM CO COM 260543103 15,730 274,912 SH   DFND 1,2,3,4 0 274,912 0
DR PEPPER SNAPPLE GROUP INC COM 26138E109 5,172 57,041 SH   DFND 1,2,3,4 0 57,041 0
DUNKIN BRANDS GROUP INC COM 265504100 20,976 400,000 SH Call DFND 1,2,3,4 0 400,000 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 257 65,100 SH Call DFND 1,2,3,4 0 65,100 0
E TRADE FINANCIAL CORP COM NEW 269246401 10,710 309,088 SH   DFND 1,2,3,4 0 309,088 0
ENTELLUS MED INC COM 29363K105 4,757 250,756 SH   DFND 1,2,3,4 0 250,756 0
FACEBOOK INC CL A 30303M102 23,777 206,668 SH   DFND 1,2,3,4 0 206,668 0
FATE THERAPEUTICS INC COM 31189P102 6,566 2,615,847 SH   DFND 1,2,3,4 0 2,615,847 0
FLEXION THERAPEUTICS INC COM 33938J106 26,238 1,379,486 SH   DFND 1,2,3,4 0 1,379,486 0
FORTIVE CORP COM 34959J108 22,757 424,342 SH   DFND 1,2,3,4 0 424,342 0
GAMING & LEISURE PPTYS INC COM 36467J108 5,480 178,954 SH   DFND 1,2,3,4 0 178,954 0
GENERAL DYNAMICS CORP COM 369550108 23,718 137,370 SH   DFND 1,2,3,4 0 137,370 0
GREAT ELM CAP GROUP INC COM NEW 39036P209 4,759 1,269,197 SH   DFND 1,2,3,4 0 1,269,197 0
GTY TECHNOLOGY HOLDINGS INC CL A G4182A102 12,600 1,200,000 SH   DFND 1,2,3,4 0 1,200,000 0
HERON THERAPEUTICS INC COM 427746102 36,852 2,813,161 SH   DFND 1,2,3,4 0 2,813,161 0
HERON THERAPEUTICS INC COM 427746102 13,559 1,035,000 SH Call DFND 1,2,3,4 0 1,035,000 0
HESS CORP COM 42809H107 62,290 1,000,000 SH Put DFND 1,2,3,4 0 1,000,000 0
HORIZON PHARMA INVT LTD NOTE 2.500% 3/1 44052TAB7 42,568 44,750,000 PRN   DFND 1,2,3,4 0 44,750,000 0
HORIZON PHARMA PLC SHS G4617B105 108,125 6,682,618 SH   DFND 1,2,3,4 0 6,682,618 0
HORIZON PHARMA PLC SHS G4617B105 72,873 4,503,900 SH Call DFND 1,2,3,4 0 4,503,900 0
INOTEK PHARMACEUTICALS CORP NOTE 5.750% 8/0 45780VAB8 5,928 5,700,000 PRN   DFND 1,2,3,4 0 5,700,000 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 9,789 173,500 SH   DFND 1,2,3,4 0 173,500 0
INTL PAPER CO COM 460146103 65,681 1,237,866 SH   DFND 1,2,3,4 0 1,237,866 0
INVUITY INC COM NEW 46187J205 4,160 723,432 SH   DFND 1,2,3,4 0 723,432 0
ISHARES TR RUSSELL 2000 ETF 464287655 40,455 300,000 SH Put DFND 1,2,3,4 0 300,000 0
JAGUAR ANIMAL HEALTH INC COM 47008L106 917 1,297,815 SH   DFND 1,2,3,4 0 1,297,815 0
KADMON HLDGS INC COM 48283N106 287 54,333 SH   DFND 1,2,3,4 0 54,333 0
KROGER CO COM 501044101 1,208 35,000 SH   DFND 1,2,3,4 0 35,000 0
LENNAR CORP CL A 526057104 15,761 367,125 SH   DFND 1,2,3,4 0 367,125 0
LEXICON PHARMACEUTICALS INC COM NEW 528872302 16,839 1,217,575 SH   DFND 1,2,3,4 0 1,217,575 0
LEXICON PHARMACEUTICALS INC COM NEW 528872302 4,149 300,000 SH Call DFND 1,2,3,4 0 300,000 0
LIBERTY MEDIA CORP DEB 4.000%11/1 530715AG6 8,330 14,000,000 PRN   DFND 1,2,3,4 0 14,000,000 0
LILLY ELI & CO COM 532457108 11,099 150,900 SH Call DFND 1,2,3,4 0 150,900 0
LINCOLN NATL CORP IND COM 534187109 30,290 457,070 SH   DFND 1,2,3,4 0 457,070 0
LOWES COS INC COM 548661107 37,323 524,786 SH   DFND 1,2,3,4 0 524,786 0
LOWES COS INC COM 548661107 21,336 300,000 SH Put DFND 1,2,3,4 0 300,000 0
LUMENTUM HLDGS INC COM 55024U109 15,772 408,064 SH   DFND 1,2,3,4 0 408,064 0
MELLANOX TECHNOLOGIES LTD SHS M51363113 3,781 92,443 SH   DFND 1,2,3,4 0 92,443 0
MONDELEZ INTL INC CL A 609207105 663 14,951 SH   DFND 1,2,3,4 0 14,951 0
MONDELEZ INTL INC CL A 609207105 28,815 650,000 SH Call DFND 1,2,3,4 0 650,000 0
MONSTER BEVERAGE CORP NEW COM 61174X109 13,863 312,645 SH   DFND 1,2,3,4 0 312,645 0
NAVIGATORS GROUP INC COM 638904102 6,806 57,798 SH   DFND 1,2,3,4 0 57,798 0
NEWELL BRANDS INC COM 651229106 43,682 978,314 SH   DFND 1,2,3,4 0 978,314 0
NEXSTAR BROADCASTING GROUP I CL A 65336K103 38,605 609,869 SH   DFND 1,2,3,4 0 609,869 0
NIVALIS THERAPEUTICS INC COM 65481J109 1,165 519,910 SH   DFND 1,2,3,4 0 519,910 0
NOBLE ENERGY INC COM 655044105 45,343 1,191,347 SH   DFND 1,2,3,4 0 1,191,347 0
NOMAD HLDGS LTD USD ORD SHS G6564A105 11,868 1,240,090 SH   DFND 1,2,3,4 0 1,240,090 0
NORTHERN TR CORP COM 665859104 33,079 371,462 SH   DFND 1,2,3,4 0 371,462 0
NOVAN INC COM 66988N106 7,096 262,625 SH   DFND 1,2,3,4 0 262,625 0
OPHTHOTECH CORP COM 683745103 97 20,000 SH Call DFND 1,2,3,4 0 20,000 0
OTONOMY INC COM 68906L105 9,617 604,860 SH   DFND 1,2,3,4 0 604,860 0
PINNACLE FOODS INC DEL COM 72348P104 11,656 218,077 SH   DFND 1,2,3,4 0 218,077 0
PINNACLE FOODS INC DEL COM 72348P104 34,743 650,000 SH Call DFND 1,2,3,4 0 650,000 0
POWERSHS DB US DOLLAR INDEX DOLL INDX BULL 73936D107 24,288 917,900 SH   DFND 1,2,3,4 0 917,900 0
PTC THERAPEUTICS INC COM 69366J200 6,601 605,000 SH   DFND 1,2,3,4 0 605,000 0
PTC THERAPEUTICS INC COM 69366J200 2,182 200,000 SH Call DFND 1,2,3,4 0 200,000 0
RECRO PHARMA INC COM 75629F109 2,507 311,072 SH   DFND 1,2,3,4 0 311,072 0
RETROPHIN INC COM 761299106 7,829 413,591 SH   DFND 1,2,3,4 0 413,591 0
SAGE THERAPEUTICS INC COM 78667J108 14,008 274,339 SH   DFND 1,2,3,4 0 274,339 0
SAGE THERAPEUTICS INC COM 78667J108 10,212 200,000 SH Put DFND 1,2,3,4 0 200,000 0
SALESFORCE COM INC COM 79466L302 14,455 211,140 SH   DFND 1,2,3,4 0 211,140 0
SELECT SECTOR SPDR TR SBI INT-ENERGY 81369Y506 7,532 100,000 SH   DFND 1,2,3,4 0 100,000 0
SELECT SECTOR SPDR TR SBI CONS DISCR 81369Y407 28,490 350,000 SH Put DFND 1,2,3,4 0 350,000 0
SHERWIN WILLIAMS CO COM 824348106 16,898 62,878 SH   DFND 1,2,3,4 0 62,878 0
SHIRE PLC SPONSORED ADR 82481R106 2,028 11,900 SH   DFND 1,2,3,4 0 11,900 0
SINCLAIR BROADCAST GROUP INC CL A 829226109 7,526 225,671 SH   DFND 1,2,3,4 0 225,671 0
SOUTHWEST AIRLS CO COM 844741108 12,919 259,200 SH   DFND 1,2,3,4 0 259,200 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 89,412 400,000 SH Put DFND 1,2,3,4 0 400,000 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 7,399 125,000 SH   DFND 1,2,3,4 0 125,000 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 11,838 200,000 SH Call DFND 1,2,3,4 0 200,000 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 17,757 300,000 SH Put DFND 1,2,3,4 0 300,000 0
SPDR SERIES TRUST S&P REGL BKG 78464A698 5,557 100,000 SH   DFND 1,2,3,4 0 100,000 0
SPDR SERIES TRUST S&P RETAIL ETF 78464A714 26,442 600,000 SH Put DFND 1,2,3,4 0 600,000 0
SUNPOWER CORP DBCV 4.000% 1/1 867652AL3 7,131 10,000,000 PRN   DFND 1,2,3,4 0 10,000,000 0
SYNERGY PHARMACEUTICALS DEL COM NEW 871639308 9,552 1,568,487 SH   DFND 1,2,3,4 0 1,568,487 0
T MOBILE US INC COM 872590104 12,068 209,845 SH   DFND 1,2,3,4 0 209,845 0
TARGA RES CORP COM 87612G101 4,861 86,694 SH   DFND 1,2,3,4 0 86,694 0
TEMPUR SEALY INTL INC COM 88023U101 17,492 256,174 SH   DFND 1,2,3,4 0 256,174 0
TJX COS INC NEW COM 872540109 5,515 73,400 SH   DFND 1,2,3,4 0 73,400 0
TONIX PHARMACEUTICALS HLDG C COM NEW 890260201 327 696,455 SH   DFND 1,2,3,4 0 696,455 0
TORCHMARK CORP COM 891027104 7,371 99,934 SH   DFND 1,2,3,4 0 99,934 0
TRINA SOLAR LIMITED DBCV 3.500% 6/1 89628EAC8 4,763 5,000,000 PRN   DFND 1,2,3,4 0 5,000,000 0
TYSON FOODS INC CL A 902494103 40,256 652,655 SH   DFND 1,2,3,4 0 652,655 0
ULTA SALON COSMETCS & FRAG I COM 90384S303 6,883 27,000 SH   DFND 1,2,3,4 0 27,000 0
UNION PAC CORP COM 907818108 65,579 632,510 SH   DFND 1,2,3,4 0 632,510 0
VANDA PHARMACEUTICALS INC COM 921659108 6,679 418,732 SH   DFND 1,2,3,4 0 418,732 0
VERSARTIS INC COM 92529L102 7,623 511,610 SH   DFND 1,2,3,4 0 511,610 0
VOYA FINL INC COM 929089100 9,636 245,700 SH   DFND 1,2,3,4 0 245,700 0
WAL-MART STORES INC COM 931142103 34,560 500,000 SH Put DFND 1,2,3,4 0 500,000 0
WPX ENERGY INC COM 98212B103 34,170 2,345,210 SH   DFND 1,2,3,4 0 2,345,210 0