The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COMMON 003654100 28,330 251,416 SH   SOLE   120,316 0 131,100
ACADIA HEALTHCARE COMMON 00404A109 29,340 886,405 SH   SOLE   449,305 0 437,100
ACADIA PHARMACEUTICALS COMMON 004225108 33,932 1,176,543 SH   SOLE   641,607 0 534,936
ACCELERON PHARMA COMMON 00434H108 8,810 345,225 SH   SOLE   84,125 0 261,100
ACCURAY INC COMMON 004397105 14,134 3,072,536 SH   SOLE   1,151,008 0 1,921,528
ADVAXIS INC COMMON 007624208 4,941 690,074 SH   SOLE   190,251 0 499,823
AERIE PHARMACEUTICALS COMMON 00771V108 8,906 235,298 SH   SOLE   67,998 0 167,300
AETNA INC COMMON 00817Y108 22,593 182,185 SH   SOLE   115,485 0 66,700
AGIOS PHARMACEUTICALS COMMON 00847X104 2,291 54,900 SH   SOLE   54,900 0 0
ALDER BIOPHARMACEUTICALS COMMON 014339105 13,923 669,351 SH   SOLE   288,151 0 381,200
ALNYLAM PHARMACEUTICALS COMMON 02043Q107 745 19,899 SH   SOLE   19,899 0 0
AMICUS THERAPEUTICS COMMON 03152W109 25,348 5,100,198 SH   SOLE   2,980,973 0 2,119,225
AVEXIS INC COMMON 05366U100 1,108 23,215 SH   SOLE   23,215 0 0
BIOGEN INC COMMON 09062X103 24,059 84,841 SH   SOLE   55,741 0 29,100
BIOMARIN PHARMACEUTICAL INC COMMON 09061G101 40,766 492,100 SH   SOLE   371,303 0 120,797
CELGENE CORP COMMON 151020104 50,233 433,981 SH   SOLE   315,081 0 118,900
CIGNA CORP COMMON 125509109 28,335 212,424 SH   SOLE   145,524 0 66,900
COLLEGIUM PHARMACEUTICAL COMMON 19459J104 32,771 2,104,756 SH   SOLE   1,120,251 0 984,505
DBV TECHNOLOGIES SP ADR 23306J101 1,349 38,401 SH   SOLE   38,401 0 0
DEXCOM INC COMMON 252131107 30,437 509,836 SH   SOLE   261,701 0 248,135
DR REDDYS LABS LTD ADR 256135203 1,456 32,155 SH   SOLE   32,155 0 0
ELI LILLY & CO COMMON 532457108 53,627 729,117 SH   SOLE   500,117 0 229,000
ENTELLUS MED INC COMMON 29363K105 2,476 130,496 SH   SOLE   0 0 130,496
ENVISION HEALTHCARE COMMON 29414D100 7,914 125,040 SH   SOLE   140 0 124,900
GLOBAL BLOOD THERAPEUTICS COMMON 37890U108 16,268 1,125,801 SH   SOLE   513,805 0 611,996
INCYTE CORPORATION COMMON 45337C102 3,447 34,374 SH   SOLE   34,374 0 0
INSMED INC COMMON 457669307 1,367 103,300 SH   SOLE   103,300 0 0
INTEGRA LIFESCIENCE COMMON 457985208 5,937 69,200 SH   SOLE   0 0 69,200
INTERCEPT PHARMACEUTICALS COMMON 45845P108 8,056 74,150 SH   SOLE   7,125 0 67,025
INTERSECT ENT INC COMMON 46071F103 6,473 534,937 SH   SOLE   342,097 0 192,840
INTUITIVE SURGIC INC COMMON 46120E602 26,899 42,416 SH   SOLE   29,858 0 12,558
K2M GROUP HOLDINGS COMMON 48273J107 3,115 155,450 SH   SOLE   250 0 155,200
KITE PHARMA INC COMMON 49803L109 16,690 372,223 SH   SOLE   176,503 0 195,720
MERCK & CO INC COMMON 58933Y105 57,329 973,832 SH   SOLE   673,932 0 299,900
MOLINA HEALTHCARE COMMON 60855R100 7,425 136,845 SH   SOLE   245 0 136,600
MOMENTA PHARMACEUTICALS COMMON 60877T100 5,711 379,500 SH   SOLE   800 0 378,700
NEUROCRINE BIOSCIENCES COMMON 64125C109 28,986 748,988 SH   SOLE   349,588 0 399,400
NEURODERM LTD ORD SHS M74231107 9,786 440,799 SH   SOLE   440,799 0 0
NOVO-NORDISK AS ADR 670100205 8,477 236,380 SH   SOLE   236,380 0 0
NUVASIVE INC COMMON 670704105 33,592 498,689 SH   SOLE   208,989 0 289,700
NXSTAGE MEDICAL COMMON 67072V103 23,361 891,313 SH   SOLE   346,057 0 545,256
PFIZER INC COMMON 717081103 57,306 1,764,343 SH   SOLE   1,215,343 0 549,000
PORTOLA PHARMACEUTICALS COMMON 737010108 31,851 1,419,404 SH   SOLE   692,362 0 727,042
PROFOUND MEDICAL COMMON 74319B106 414 495,900 SH   SOLE   495,900 0 0
PRONAI THERAPEUTICS COMMON 074346L10 367 201,660 SH   SOLE   201,660 0 0
PROTHENA CORP PLC SHS G72800108 6,082 123,646 SH   SOLE   23,646 0 100,000
PTC THERAPEUTICS I COMMON 69366J200 1,343 123,135 SH   SOLE   123,135 0 0
RA PHARMACEUTICALS COMMON 74933V108 3,842 252,940 SH   SOLE   105,500 0 147,440
SAGE THERAPEUTICS COMMON 78667J108 1,425 27,899 SH   SOLE   27,899 0 0
SAREPTA THERAPEUTICS COMMON 803607100 790 28,799 SH   SOLE   28,799 0 0
SHIRE PLC SP ADR 82481R106 26,947 158,158 SH   SOLE   158,158 0 0
SURGICAL CARE AFFILIATES COMMON 86881L106 4,548 98,300 SH   SOLE   0 0 98,300
TELADOC INC COMMON 87918A105 25,903 1,569,878 SH   SOLE   754,900 0 814,978
TRILLIUM THERAPEUTICS COMMON 89620X506 565 100,000 SH   SOLE   100,000 0 0
WRIGHT MED GROUP N V ORD SHS 0.03 PAR N96617118 10,547 458,977 SH   SOLE   305 0 458,672