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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 32,710 903,833 SH   SOLE   903,833 0 0
COLUCID PHARMACEUTICALS INC COM 19716T101 120,423 3,156,563 SH   SOLE   3,156,563 0 0
CORVUS PHARMACEUTICALS INC COM 221015100 53,036 3,224,046 SH   SOLE   3,224,046 0 0
FLEXION THERAPEUTICS INC COM 33938J106 21,449 1,097,718 SH   SOLE   1,097,718 0 0
HTG MOLECULAR DIAGNOSTICS INC COM 40434H104 2,906 1,280,185 SH   SOLE   1,280,185 0 0
INOGEN INC COM 45780L104 212,604 3,549,320 SH   SOLE   3,549,320 0 0
INVUITY INC COM 46187J205 17,636 1,285,448 SH   SOLE   1,285,448 0 0
MERUS N V COM N5749R100 23,624 1,410,417 SH   SOLE   1,410,417 0 0
NABRIVA THERAPEUTICS AG COM 62957M104 7,872 1,116,660 SH   SOLE   1,116,660 0 0
OPHTHOTECH CORP COM 683745103 166,552 3,610,487 SH   SOLE   3,610,487 0 0
OPKO HEALTH INC COM 68375N103 3 259 SH   SOLE   259 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 88,774 3,367,763 SH   SOLE   3,367,763 0 0
SPECTRANETICS CORP COM 84760C107 28,997 1,155,722 SH   SOLE   1,155,722 0 0
VANGUARD INDEX FDS TOTAL STK MKT 922908769 239,927 2,155,100 SH   SOLE   2,155,100 0 0
VANGUARD INTL EQUITY INDEX F FTSE EUROPE ETF 922042874 102,382 2,101,000 SH   SOLE   2,101,000 0 0
WRIGHT MED GROUP N V RIGHT 03/01/2019 N96617126 6,055 4,622,032 PRN   SOLE   0 0 4,622,032
XENON PHARMACEUTICALS INC COM 98420N105 1,033 127,563 SH   SOLE   127,563 0 0