The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 12,382 200,000 SH Call DFND 1,2,3 0 200,000 0
ADVANCE AUTO PARTS INC COM 00751Y106 26,807 165,855 SH   DFND 1,2,3 0 165,855 0
ALLERGAN PLC PFD CONV SER A G0177J116 17,505 21,000 PRN   DFND 1,2,3 0 21,000 0
ALPHABET INC CAP STK CL A 02079K305 56,707 80,603 SH   DFND 1,2,3 0 80,603 0
AMERICAN AIRLS GROUP INC COM 02376R102 338 450,000 SH   DFND 1,2,3 0 450,000 0
ANACOR PHARMACEUTICALS INC COM 032420101 5,407 54,476 SH   DFND 1,2,3 0 54,476 0
ANTARES PHARMA INC COM 036642106 1,343 1,278,868 SH   DFND 1,2,3 0 1,278,868 0
ASTRAZENECA PLC SPONSORED ADR 046353108 1,549 51,300 SH Call DFND 1,2,3 0 51,300 0
BEACON ROOFING SUPPLY INC COM 073685109 8,152 179,278 SH   DFND 1,2,3 0 179,278 0
CDK GLOBAL INC COM 12508E101 40,032 721,427 SH   DFND 1,2,3 0 721,427 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 36,971 161,699 SH   DFND 1,2,3 0 161,699 0
CHUBB LIMITED COM H1467J104 24,231 185,383 SH   DFND 1,2,3 0 185,383 0
CITIGROUP INC COM NEW 172967424 1,261 29,740 SH   DFND 1,2,3 0 29,740 0
CITIGROUP INC COM NEW 172967424 40,271 950,000 SH Call DFND 1,2,3 0 950,000 0
COMERICA INC COM 200340107 20,808 505,919 SH   DFND 1,2,3 0 505,919 0
CYMABAY THERAPEUTICS INC COM 23257D103 1,668 958,822 SH   DFND 1,2,3 0 958,822 0
DANAHER CORP DEL COM 235851102 26,638 263,742 SH   DFND 1,2,3 0 263,742 0
DEVON ENERGY CORP NEW COM 25179M103 19,377 534,530 SH   DFND 1,2,3 0 534,530 0
DIPEXIUM PHARMACEUTICALS INC COM 25456J104 9,614 970,124 SH   DFND 1,2,3 0 970,124 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 12,324 845,300 SH   DFND 1,2,3 0 845,300 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 11,664 800,000 SH Call DFND 1,2,3 0 800,000 0
E M C CORP MASS COM 268648102 39,731 1,462,300 SH   DFND 1,2,3 0 1,462,300 0
ENDURANCE SPECIALTY HLDGS LT SHS G30397106 6,924 103,100 SH   DFND 1,2,3 0 103,100 0
ENTELLUS MED INC COM 29363K105 4,116 225,280 SH   DFND 1,2,3 0 225,280 0
EXELIXIS INC COM 30161Q104 7,920 1,014,130 SH   DFND 1,2,3 0 1,014,130 0
EXPRESS SCRIPTS HLDG CO COM 30219G108 7,580 100,000 SH Put DFND 1,2,3 0 100,000 0
FATE THERAPEUTICS INC COM 31189P102 3,838 2,257,920 SH   DFND 1,2,3 0 2,257,920 0
FIDELITY NATIONAL FINANCIAL FNF GROUP COM 31620R303 20,608 549,534 SH   DFND 1,2,3 0 549,534 0
FLAGSTAR BANCORP INC COM PAR .001 337930705 8,247 337,873 SH   DFND 1,2,3 0 337,873 0
FLEXION THERAPEUTICS INC COM 33938J106 16,424 1,097,463 SH   DFND 1,2,3 0 1,097,463 0
GAMING & LEISURE PPTYS INC COM 36467J108 9,924 287,808 SH   DFND 1,2,3 0 287,808 0
GIGAMON INC COM 37518B102 5,048 135,000 SH   DFND 1,2,3 0 135,000 0
GILEAD SCIENCES INC COM 375558103 12,513 150,000 SH Call DFND 1,2,3 0 150,000 0
GREAT ELM CAP GROUP INC COM 39036P100 3,592 545,020 SH   DFND 1,2,3 0 545,020 0
GW PHARMACEUTICALS PLC ADS 36197T103 3,754 41,000 SH Call DFND 1,2,3 0 41,000 0
HCA HOLDINGS INC COM 40412C101 1,983 25,752 SH   DFND 1,2,3 0 25,752 0
HAIN CELESTIAL GROUP INC COM 405217100 13,483 271,016 SH   DFND 1,2,3 0 271,016 0
HERBALIFE LTD COM USD SHS G4412G101 8,780 150,000 SH   DFND 1,2,3 0 150,000 0
HERON THERAPEUTICS INC COM 427746102 16,445 911,107 SH   DFND 1,2,3 0 911,107 0
HERON THERAPEUTICS INC COM 427746102 6,799 376,700 SH Call DFND 1,2,3 0 376,700 0
HORIZON PHARMA PLC SHS G4617B105 66,789 4,055,167 SH   DFND 1,2,3 0 4,055,167 0
HORIZON PHARMA PLC SHS G4617B105 32,240 1,957,500 SH Call DFND 1,2,3 0 1,957,500 0
HORIZON PHARMA INVT LTD NOTE 2.500% 3/1 44052TAB7 29,227 32,250,000 PRN   DFND 1,2,3 0 32,250,000 0
HUNTSMAN CORP COM 447011107 22,990 1,709,302 SH   DFND 1,2,3 0 1,709,302 0
INVUITY INC COM NEW 46187J205 2,088 219,150 SH   DFND 1,2,3 0 219,150 0
ISHARES MSCI BRZ CAP ETF 464286400 6,035 200,000 SH Put DFND 1,2,3 0 200,000 0
ISHARES TR RUSSELL 2000 ETF 464287655 68,988 600,000 SH Put DFND 1,2,3 0 600,000 0
JAGUAR ANIMAL HEALTH INC COM 47008L106 1,673 909,217 SH   DFND 1,2,3 0 909,217 0
KEMPHARM INC COM 488445107 1,035 259,967 SH   DFND 1,2,3 0 259,967 0
LEXICON PHARMACEUTICALS INC COM NEW 528872302 7,094 494,380 SH   DFND 1,2,3 0 494,380 0
LIBERTY MEDIA CORP DEB 4.000%11/1 530715AG6 6,930 12,000,000 PRN   DFND 1,2,3 0 12,000,000 0
LILLY ELI & CO COM 532457108 7,875 100,000 SH Call DFND 1,2,3 0 100,000 0
LOWES COS INC COM 548661107 36,239 457,740 SH   DFND 1,2,3 0 457,740 0
LUMENTUM HLDGS INC COM 55024U109 5,445 225,000 SH   DFND 1,2,3 0 225,000 0
MASTERCARD INC CL A 57636Q104 9,995 113,500 SH   DFND 1,2,3 0 113,500 0
MEDIVATION INC COM 58501N101 2,840 47,100 SH   DFND 1,2,3 0 47,100 0
MEDIVATION INC COM 58501N101 6,030 100,000 SH Call DFND 1,2,3 0 100,000 0
MEDIWOUND LTD ORD SHS M68830104 667 84,590 SH   DFND 1,2,3 0 84,590 0
MELLANOX TECHNOLOGIES LTD SHS M51363113 15,965 332,879 SH   DFND 1,2,3 0 332,879 0
MONDELEZ INTL INC CL A 609207105 13,653 300,000 SH Call DFND 1,2,3 0 300,000 0
MONSTER BEVERAGE CORP NEW COM 61174X109 7,473 46,500 SH   DFND 1,2,3 0 46,500 0
NEWELL BRANDS INC COM 651229106 150,458 3,097,756 SH   DFND 1,2,3 0 3,097,756 0
NEWFIELD EXPL CO COM 651290108 27,843 630,224 SH   DFND 1,2,3 0 630,224 0
NEXSTAR BROADCASTING GROUP I CL A 65336K103 32,519 683,469 SH   DFND 1,2,3 0 683,469 0
NIVALIS THERAPEUTICS INC COM 65481J109 2,492 541,700 SH   DFND 1,2,3 0 541,700 0
NOBLE ENERGY INC COM 655044105 45,889 1,279,308 SH   DFND 1,2,3 0 1,279,308 0
NOMAD HLDGS LTD USD ORD SHS G6564A105 10,204 1,278,750 SH   DFND 1,2,3 0 1,278,750 0
OTONOMY INC COM 68906L105 5,837 367,587 SH   DFND 1,2,3 0 367,587 0
PACIRA PHARMACEUTICALS INC COM 695127100 7,134 211,500 SH   DFND 1,2,3 0 211,500 0
PBF ENERGY INC CL A 69318G106 13,162 553,500 SH   DFND 1,2,3 0 553,500 0
PINNACLE FOODS INC DEL COM 72348P104 9,258 200,000 SH   DFND 1,2,3 0 200,000 0
PROOFPOINT INC COM 743424103 14,195 225,000 SH   DFND 1,2,3 0 225,000 0
REGENERON PHARMACEUTICALS COM 75886F107 8,731 25,000 SH Call DFND 1,2,3 0 25,000 0
RENAISSANCERE HOLDINGS LTD COM G7496G103 12,777 108,800 SH   DFND 1,2,3 0 108,800 0
SAGE THERAPEUTICS INC COM 78667J108 5,728 190,100 SH   DFND 1,2,3 0 190,100 0
SAGE THERAPEUTICS INC COM 78667J108 9,039 300,000 SH Put DFND 1,2,3 0 300,000 0
SINCLAIR BROADCAST GROUP INC CL A 829226109 19,508 653,310 SH   DFND 1,2,3 0 653,310 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 167,580 800,000 SH Call DFND 1,2,3 0 800,000 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 125,685 600,000 SH Put DFND 1,2,3 0 600,000 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 14,061 260,000 SH Put DFND 1,2,3 0 260,000 0
SELECT SECTOR SPDR TR SBI CONS STPLS 81369Y308 2,758 50,000 SH Put DFND 1,2,3 0 50,000 0
STANLEY BLACK & DECKER INC COM 854502101 10,566 95,000 SH   DFND 1,2,3 0 95,000 0
SYNERGY PHARMACEUTICALS DEL COM NEW 871639308 6,093 1,603,334 SH   DFND 1,2,3 0 1,603,334 0
TETRALOGIC PHARMACEUTICALS C NOTE 8.000% 6/1 88165UAB5 323 2,000,000 PRN   DFND 1,2,3 0 2,000,000 0
T MOBILE US INC COM 872590104 19,239 444,622 SH   DFND 1,2,3 0 444,622 0
TARGA RES CORP COM 87612G101 14,251 338,175 SH   DFND 1,2,3 0 338,175 0
TESARO INC COM 881569107 2,101 25,000 SH Call DFND 1,2,3 0 25,000 0
TESARO INC COM 881569107 19,390 230,700 SH Put DFND 1,2,3 0 230,700 0
TONIX PHARMACEUTICALS HLDG C COM NEW 890260201 4,174 2,097,248 SH   DFND 1,2,3 0 2,097,248 0
TREEHOUSE FOODS INC COM 89469A104 7,596 74,000 SH   DFND 1,2,3 0 74,000 0
TRINA SOLAR LIMITED DBCV 3.500% 6/1 89628EAC8 4,271 5,000,000 PRN   DFND 1,2,3 0 5,000,000 0
TYSON FOODS INC CL A 902494103 15,637 234,117 SH   DFND 1,2,3 0 234,117 0
U S SILICA HLDGS INC COM 90346E103 21,619 627,171 SH   DFND 1,2,3 0 627,171 0
UNITED TECHNOLOGIES CORP COM 913017109 22,949 223,783 SH   DFND 1,2,3 0 223,783 0
VANDA PHARMACEUTICALS INC COM 921659108 7,213 644,568 SH   DFND 1,2,3 0 644,568 0
VANDA PHARMACEUTICALS INC COM 921659108 3,357 300,000 SH Call DFND 1,2,3 0 300,000 0
VERSARTIS INC COM 92529L102 3,498 316,244 SH   DFND 1,2,3 0 316,244 0
VISA INC COM CL A 92826C839 14,599 196,833 SH   DFND 1,2,3 0 196,833 0
WPX ENERGY INC COM 98212B103 21,028 2,258,620 SH   DFND 1,2,3 0 2,258,620 0
WESTROCK CO COM 96145D105 11,790 303,331 SH   DFND 1,2,3 0 303,331 0