The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| AEROHIVE NETWORKS INC | COM | 007786106 | 32,677 | 4,681,455 | SH | DFND | 4,681,455 | 0 | 0 | ||
| AGILE THERAPEUTICS INC | COM | 00847L100 | 1,147 | 133,488 | SH | DFND | 133,488 | 0 | 0 | ||
| ARCA BIOPHARMA INC | COM | 00211Y209 | 11,755 | 10,221,465 | SH | DFND | 10,221,465 | 0 | 0 | ||
| ARDELYX INC | COM | 039697107 | 164,397 | 10,294,096 | SH | DFND | 10,294,096 | 0 | 0 | ||
| ARQULE INC | COM | 04269E107 | 4,033 | 2,520,316 | SH | DFND | 2,520,316 | 0 | 0 | ||
| AURINIA PHARMACEUTICALS INC | COM | 05156V102 | 7,691 | 2,546,843 | SH | DFND | 2,546,843 | 0 | 0 | ||
| CARE COM INC | COM | 141633107 | 19,305 | 3,260,989 | SH | DFND | 3,260,989 | 0 | 0 | ||
| CHANNELADVISOR CORP | COM | 159179100 | 6,652 | 556,692 | SH | DFND | 556,692 | 0 | 0 | ||
| CLOVIS ONCOLOGY INC | COM | 189464100 | 100,174 | 1,139,890 | SH | DFND | 1,139,890 | 0 | 0 | ||
| CVENT INC | COM | 23247G109 | 6,293 | 244,106 | SH | DFND | 244,106 | 0 | 0 | ||
| DERMIRA INC | COM | 24983L104 | 61,542 | 3,506,649 | SH | DFND | 3,506,649 | 0 | 0 | ||
| EPIZYME INC | COM | 29428V104 | 123,594 | 5,149,740 | SH | DFND | 5,149,740 | 0 | 0 | ||
| EXELIXIS INC | COM | 30161Q104 | 8,298 | 2,207,000 | SH | DFND | 2,207,000 | 0 | 0 | ||
| GLYCOMIMETICS INC | COM | 38000Q102 | 68,172 | 8,575,135 | SH | DFND | 8,575,135 | 0 | 0 | ||
| GROUPON INC | COM CL A | 399473107 | 222,190 | 44,172,953 | SH | DFND | 44,172,953 | 0 | 0 | ||
| LEXICON PHARMACEUTICALS INC | COM | 528872104 | 19,177 | 2,382,286 | SH | DFND | 2,382,286 | 0 | 0 | ||
| LOXO ONCOLOGY INC | COM | 548862101 | 32,313 | 1,792,207 | SH | DFND | 1,792,207 | 0 | 0 | ||
| MILLENNIAL MEDIA INC | COM | 60040N105 | 13,324 | 8,224,752 | SH | DFND | 8,224,752 | 0 | 0 | ||
| NEVRO CORP | COM | 64157F103 | 53,397 | 993,428 | SH | DFND | 993,428 | 0 | 0 | ||
| OPOWER INC | COM | 68375Y109 | 103,559 | 8,997,290 | SH | DFND | 8,997,290 | 0 | 0 | ||
| OREXIGEN THERAPEUTICS INC | COM | 686164104 | 18,360 | 3,709,000 | SH | DFND | 3,709,000 | 0 | 0 | ||
| PARATEK PHARMACEUTICALS INC | COM | 699374302 | 4,481 | 173,892 | SH | DFND | 173,892 | 0 | 0 | ||
| RIGEL PHARMACEUTICALS INC | COM | 766559603 | 10,411 | 3,243,150 | SH | DFND | 3,243,150 | 0 | 0 | ||
| ROKA BIOSCIENCE INC | COM | 775431109 | 8,373 | 3,220,433 | SH | DFND | 3,220,433 | 0 | 0 | ||
| SUNESIS PHARMACEUTICALS INC | COM | 867328502 | 14,025 | 4,659,333 | SH | DFND | 4,659,333 | 0 | 0 | ||
| SUPERNUS PHARMACEUTICALS INC | COM | 868459108 | 129,748 | 7,641,250 | SH | DFND | 7,641,250 | 0 | 0 | ||
| TARGACEPT INC | COM | 87611R306 | 12,741 | 4,566,666 | SH | DFND | 4,566,666 | 0 | 0 | ||
| TESARO INC | COM | 881569107 | 520,542 | 8,854,255 | SH | DFND | 8,854,255 | 0 | 0 | ||
| TRACON PHARMACEUTICALS INC | COM | 89237H100 | 21,410 | 1,889,652 | SH | DFND | 1,889,652 | 0 | 0 | ||
| TREVENA INC | COM | 89532E109 | 30,121 | 4,811,691 | SH | DFND | 4,811,691 | 0 | 0 | ||
| TRIVASCULAR TECHNOLOGIES INC | COM | 89685A102 | 21,107 | 3,945,191 | SH | DFND | 3,945,191 | 0 | 0 | ||
| VITAE PHARMACEUTICALS INC | COM | 92847N103 | 37,630 | 2,613,199 | SH | DFND | 2,613,199 | 0 | 0 | ||
| ZHONE TECHNOLOGIES INC | COM | 98950P884 | 10,710 | 4,781,290 | SH | DFND | 4,781,290 | 0 | 0 | ||
| ZOSANO PHARMA CORP | COM | 98979H103 | 15,649 | 2,158,543 | SH | DFND | 2,158,543 | 0 | 0 | ||