The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| AEROHIVE NETWORKS INC | COM | 007786106 | 27,995 | 4,681,455 | SH | DFND | 4,681,455 | 0 | 0 | ||
| AGILE THERAPEUTICS INC | COM | 00847L100 | 900 | 133,488 | SH | DFND | 133,488 | 0 | 0 | ||
| AKARI THERAPEUTICS PLC | ADR | 00972G108 | 645 | 26,894 | SH | DFND | 26,894 | 0 | 0 | ||
| ARCA BIOPHARMA INC | COM PAR $.001 | 00211Y407 | 7,243 | 1,460,209 | SH | DFND | 1,460,209 | 0 | 0 | ||
| ARDELYX INC | COM | 039697107 | 177,882 | 10,294,096 | SH | DFND | 10,294,096 | 0 | 0 | ||
| ARQULE INC | COM | 04269E107 | 4,713 | 2,520,316 | SH | DFND | 2,520,316 | 0 | 0 | ||
| AURINIA PHARMACEUTICALS INC | COM | 05156V102 | 7,233 | 2,546,843 | SH | DFND | 2,546,843 | 0 | 0 | ||
| CARE COM INC | COM | 141633107 | 16,761 | 3,260,989 | SH | DFND | 3,260,989 | 0 | 0 | ||
| CATALYST BIOSCIENCES INC | COM | 14888D109 | 3,040 | 652,380 | SH | DFND | 652,380 | 0 | 0 | ||
| CHAMPIONS ONCOLOGY INC | COM | 15870P307 | 8,359 | 1,562,500 | SH | DFND | 1,562,500 | 0 | 0 | ||
| CHANNELADVISOR CORP | COM | 159179100 | 5,534 | 556,692 | SH | DFND | 556,692 | 0 | 0 | ||
| CLOVIS ONCOLOGY INC | COM | 189464100 | 104,824 | 1,139,890 | SH | DFND | 1,139,890 | 0 | 0 | ||
| CVENT INC | COM | 23247G109 | 8,217 | 244,106 | SH | DFND | 244,106 | 0 | 0 | ||
| DERMIRA INC | COM | 24983L104 | 81,845 | 3,506,649 | SH | DFND | 3,506,649 | 0 | 0 | ||
| EPIZYME INC | COM | 29428V104 | 66,226 | 5,149,740 | SH | DFND | 5,149,740 | 0 | 0 | ||
| EXELIXIS INC | COM | 30161Q104 | 12,381 | 2,207,000 | SH | DFND | 2,207,000 | 0 | 0 | ||
| GLYCOMIMETICS INC | COM | 38000Q102 | 48,021 | 8,575,135 | SH | DFND | 8,575,135 | 0 | 0 | ||
| GROUPON INC | COM CL A | 399473107 | 144,004 | 44,172,953 | SH | DFND | 44,172,953 | 0 | 0 | ||
| LEXICON PHARMACEUTICALS INC | COM | 528872104 | 25,586 | 2,382,286 | SH | DFND | 2,382,286 | 0 | 0 | ||
| LOXO ONCOLOGY INC | COM | 548862101 | 31,328 | 1,792,207 | SH | DFND | 1,792,207 | 0 | 0 | ||
| MILLENNIAL MEDIA INC | COM | 60040N105 | 14,393 | 8,224,752 | SH | DFND | 8,224,752 | 0 | 0 | ||
| NEVRO CORP | COM | 64157F103 | 46,085 | 993,428 | SH | DFND | 993,428 | 0 | 0 | ||
| OPOWER INC | COM | 68375Y109 | 80,166 | 8,997,290 | SH | DFND | 8,997,290 | 0 | 0 | ||
| OREXIGEN THERAPEUTICS INC | COM | 686164104 | 7,826 | 3,709,000 | SH | DFND | 3,709,000 | 0 | 0 | ||
| PARATEK PHARMACEUTICALS INC | COM | 699374302 | 2,375 | 125,004 | SH | DFND | 125,004 | 0 | 0 | ||
| RIGEL PHARMACEUTICALS INC | COM | 766559603 | 8,011 | 3,243,150 | SH | DFND | 3,243,150 | 0 | 0 | ||
| ROKA BIOSCIENCE INC | COM | 775431109 | 6,280 | 3,220,433 | SH | DFND | 3,220,433 | 0 | 0 | ||
| SUNESIS PHARMACEUTICALS INC | COM | 867328601 | 4,609 | 5,689,644 | SH | DFND | 5,689,644 | 0 | 0 | ||
| SUPERNUS PHARMACEUTICALS INC | COM | 868459108 | 107,207 | 7,641,250 | SH | DFND | 7,641,250 | 0 | 0 | ||
| TESARO INC | COM | 881569107 | 355,056 | 8,854,255 | SH | DFND | 8,854,255 | 0 | 0 | ||
| TRACON PHARMACEUTICALS INC | COM | 89237H100 | 18,462 | 1,889,652 | SH | DFND | 1,889,652 | 0 | 0 | ||
| TREVENA INC | COM | 89532E109 | 49,801 | 4,811,691 | SH | DFND | 4,811,691 | 0 | 0 | ||
| TRIVASCULAR TECHNOLOGIES INC | COM | 89685A102 | 19,726 | 3,945,191 | SH | DFND | 3,945,191 | 0 | 0 | ||
| ZHONE TECHNOLOGIES INC | COM | 98950P884 | 6,550 | 4,781,290 | SH | DFND | 4,781,290 | 0 | 0 | ||
| ZOSANO PHARMA CORP | COM | 98979H103 | 8,548 | 2,158,543 | SH | DFND | 2,158,543 | 0 | 0 | ||